phenoxybenzamine has been researched along with Urinary Incontinence in 22 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Urinary Incontinence: Involuntary loss of URINE, such as leaking of urine. It is a symptom of various underlying pathological processes. Major types of incontinence include URINARY URGE INCONTINENCE and URINARY STRESS INCONTINENCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our results indicate the therapeutic value of ephedrine sulfate and propranolol in stress urinary incontinence; phenoxybenzamine in neurogenic vesical dysfunction and functional outlet obstruction; phenoxybenzamine plus bethanechol in atonic neurogenic bladder; and imipramine in enuresis." | 3.65 | Cholinergic and adrenergic neuroreceptors in urinary tract of female dogs. Evaluation of function with pharmacodynamics. ( Gonick, P; Heber, D; Khanna, OP, 1975) |
| "Forty-three children with overt neurological disease and neuropathic vesicourethral dysfunction were entered into a trial comparing clean intermittent catheterisation (CIC) with manual expression combined with drug treatment (non-CIC)." | 2.65 | Neuropathic vesicourethral dysfunction in children. A trial comparing clean intermittent catheterisation with manual expression combined with drug treatment. ( Borzyskowski, M; Chantler, C; Haycock, GB; Joyce, MR; Kinder, CH; Mundy, AR; Neville, BG; Park, L, 1982) |
| "Imipramine was occasionally of benefit." | 1.26 | The results of conservative management of neurogenic vesical dysfunction in children. ( Johnston, JH; Shapiro, SR, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (95.45) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schütz, W | 1 |
| Koyanagi, T | 1 |
| Lindholm, P | 2 |
| Lose, G | 2 |
| Kiruluta, HG | 2 |
| Andrews, K | 1 |
| Borzyskowski, M | 1 |
| Mundy, AR | 1 |
| Neville, BG | 1 |
| Park, L | 1 |
| Kinder, CH | 1 |
| Joyce, MR | 1 |
| Chantler, C | 1 |
| Haycock, GB | 1 |
| Watanabe, Y | 1 |
| Sokabe, H | 1 |
| Watanabe, TX | 1 |
| Fernandez, PG | 1 |
| Sahni, S | 1 |
| Galway, BA | 1 |
| Granter, S | 1 |
| McDonald, J | 1 |
| Stockamp, K | 1 |
| Herrmann, H | 1 |
| Schreiter, F | 1 |
| Khanna, OP | 3 |
| Awad, SA | 1 |
| Downie, JW | 1 |
| Heber, D | 2 |
| Gonick, P | 2 |
| Elkouss, G | 1 |
| Shapiro, SR | 1 |
| Johnston, JH | 2 |
| Westmore, DD | 1 |
| Low, JA | 1 |
| Stanton, SL | 1 |
| Cardozo, LD | 1 |
| Kerr-Wilson, R | 1 |
| Harrison, NW | 1 |
| Whitfield, HN | 1 |
| Williams, DI | 1 |
| Farkas, A | 1 |
| Castro-Gago, M | 1 |
| Novo, I | 1 |
| Cimadevila, A | 1 |
| Peña, J | 1 |
| Rodriguez-Núñez, A | 1 |
| Marqués'-Queimadelos, A | 1 |
| Perrigot, M | 1 |
| Vannier, A | 1 |
| Bor, Y | 1 |
| Kleeman, FJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prophylactic Tamsulosin in Prevention of Post-operative Urinary Retention in Men After Transanal Endoscopic Microsurgery: A Multicenter Randomized, Double-blind, Placebo-controlled Clinical Trial[NCT03314025] | Phase 2 | 158 participants (Anticipated) | Interventional | 2017-10-06 | Recruiting | ||
| Evaluating the Effect of Tamsulosin on Postoperative Urinary Retention in Women Undergoing Same Day Hospital Discharge Following Pelvic Reconstructive Surgery: A Randomized Trial[NCT04682366] | Phase 4 | 4 participants (Actual) | Interventional | 2021-10-19 | Terminated (stopped due to Challenges in enrollment led to decission for termination) | ||
| The Impact of Tamsulosin on Duration of Post-Operative Urinary Retention in Women Undergoing Pelvic Reconstructive Surgery- A Double Blind, Randomized, Placebo-Controlled Study[NCT04597372] | Phase 2 | 154 participants (Anticipated) | Interventional | 2021-11-03 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for phenoxybenzamine and Urinary Incontinence
| Article | Year |
|---|---|
Disorders of micturition: neuropharmacologic basis and results of drug therapy.
Topics: Adult; Aged; Animals; Cats; Child; Dogs; Enuresis; Female; Humans; Imipramine; Male; Neurotransmitte | 1976 |
Pharmacologic treatment of disorders of bladder and urethra: a review.
Topics: Adrenergic alpha-Agonists; Bethanechol Compounds; Female; Humans; Male; Parasympatholytics; Phenoxyb | 1979 |
2 trials available for phenoxybenzamine and Urinary Incontinence
| Article | Year |
|---|---|
Neuropathic vesicourethral dysfunction in children. A trial comparing clean intermittent catheterisation with manual expression combined with drug treatment.
Topics: Bethanechol Compounds; Child; Clinical Trials as Topic; Ephedrine; Follow-Up Studies; Humans; Phenox | 1982 |
Prophylactic phenoxybenzamine in the prevention of postoperative retention of urine after vaginal repair: a prospective randomized double-blind trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Middle Aged; Phenoxybenzamine; Postoperative Compl | 1985 |
Prophylactic phenoxybenzamine in the prevention of postoperative retention of urine after vaginal repair: a prospective randomized double-blind trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Middle Aged; Phenoxybenzamine; Postoperative Compl | 1985 |
Prophylactic phenoxybenzamine in the prevention of postoperative retention of urine after vaginal repair: a prospective randomized double-blind trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Middle Aged; Phenoxybenzamine; Postoperative Compl | 1985 |
Prophylactic phenoxybenzamine in the prevention of postoperative retention of urine after vaginal repair: a prospective randomized double-blind trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Middle Aged; Phenoxybenzamine; Postoperative Compl | 1985 |
Prophylactic phenoxybenzamine in the prevention of postoperative retention of urine after vaginal repair: a prospective randomized double-blind trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Middle Aged; Phenoxybenzamine; Postoperative Compl | 1985 |
Prophylactic phenoxybenzamine in the prevention of postoperative retention of urine after vaginal repair: a prospective randomized double-blind trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Middle Aged; Phenoxybenzamine; Postoperative Compl | 1985 |
Prophylactic phenoxybenzamine in the prevention of postoperative retention of urine after vaginal repair: a prospective randomized double-blind trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Middle Aged; Phenoxybenzamine; Postoperative Compl | 1985 |
Prophylactic phenoxybenzamine in the prevention of postoperative retention of urine after vaginal repair: a prospective randomized double-blind trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Middle Aged; Phenoxybenzamine; Postoperative Compl | 1985 |
Prophylactic phenoxybenzamine in the prevention of postoperative retention of urine after vaginal repair: a prospective randomized double-blind trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Middle Aged; Phenoxybenzamine; Postoperative Compl | 1985 |
18 other studies available for phenoxybenzamine and Urinary Incontinence
| Article | Year |
|---|---|
[Drug therapy of urinary incontinence].
Topics: Adrenergic alpha-Antagonists; Baclofen; Benzilates; Etilefrine; Humans; Parasympatholytics; Phenoxyb | 1980 |
Studies on the sphincteric system located distally in the urethra: the external urethral sphincter revisited.
Topics: Electromyography; Etilefrine; Humans; Male; Muscles; Phenoxybenzamine; Phentolamine; Pressure; Prost | 1980 |
[Laughter incontinence treated with alpha receptor blockaders].
Topics: Adrenergic alpha-Antagonists; Adult; Female; Humans; Laughter; Phenoxybenzamine; Urinary Incontinenc | 1982 |
Urinary incontinence secondary to drugs.
Topics: Antihypertensive Agents; Antipsychotic Agents; Humans; Methyldopa; Phenoxybenzamine; Phentolamine; P | 1983 |
Combined effects of phenoxybenzamine and propranolol in hypertensive rats.
Topics: Animals; Antihypertensive Agents; Body Weight; Heart Rate; Hypertension; Male; Phenoxybenzamine; Pro | 1980 |
Urinary incontinence due to interaction of phenoxybenzamine and alpha-methyldopa.
Topics: Drug Interactions; Female; Humans; Methyldopa; Middle Aged; Phenoxybenzamine; Sympathectomy; Urinary | 1981 |
Conservative bladder treatment in myelodysplasia. Differentiation of patients by cystomanometry.
Topics: Adolescent; Child; Child, Preschool; Colon; Diazepam; Dilatation, Pathologic; Female; Humans; Imipra | 1976 |
Cholinergic and adrenergic neuroreceptors in urinary tract of female dogs. Evaluation of function with pharmacodynamics.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bethanechol Compounds; Dogs; Enu | 1975 |
Imipramine hydrochloride: pharmacodynamic effects on lower urinary tract of female dogs.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Blood Pressure; Dogs; Female; Imipramine; Male; Phenox | 1975 |
The results of conservative management of neurogenic vesical dysfunction in children.
Topics: Child; Follow-Up Studies; Humans; Imipramine; Kidney Diseases; Methods; Phenoxybenzamine; Postoperat | 1977 |
Urinary incontinence: which drugs to use.
Topics: Bethanechol Compounds; Ephedrine; Humans; Imipramine; Parasympatholytics; Phenoxybenzamine; Urinary | 1979 |
Urethral behavior during the involuntary detrusor contraction.
Topics: Humans; Male; Muscle Contraction; Parasympathetic Nervous System; Phenoxybenzamine; Phentolamine; Pr | 1977 |
Treatment of delayed onset of spontaneous voiding after surgery for incontinence.
Topics: Adult; Anxiety; Bethanechol Compounds; Diazepam; Female; Humans; Male; Phenoxybenzamine; Postoperati | 1979 |
The place of alpha-blocking drugs in the treatment of children with neuropathic bladders.
Topics: Child; Child, Preschool; Female; Humans; Male; Phenoxybenzamine; Urinary Bladder, Neurogenic; Urinar | 1977 |
Congenital neuropathic bladder: practicalities and possibilities of conservational management.
Topics: Adolescent; Child; Child, Preschool; Dilatation; Female; Humans; Hydronephrosis; Male; Phenoxybenzam | 1975 |
Management of neurogenic bladder dysfunction secondary to myelomeningocele.
Topics: Adolescent; Atropine; Child; Child, Preschool; Ephedrine; Female; Humans; Imipramine; Longitudinal S | 1990 |
[Alpha adrenergic blocking agents in disorders of the bladder sphincter].
Topics: Adrenergic alpha-Antagonists; Adult; Female; Humans; Male; Moxisylyte; Nicergoline; Phenoxybenzamine | 1986 |
The physiology of the internal urinary sphincter.
Topics: Aged; Autonomic Agents; Autonomic Nervous System; Child; Electric Stimulation; Female; Humans; Male; | 1970 |