Page last updated: 2024-11-02

phenoxybenzamine and Urethral Diseases

phenoxybenzamine has been researched along with Urethral Diseases in 7 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Urethral Diseases: Pathological processes involving the URETHRA.

Research Excerpts

ExcerptRelevanceReference
"Treatment of patients with suspected bladder neck obstruction with this agent provides a reversible method of decreasing urethral resistance without the potentially harmful effects of surgical bladder neck revision."5.25Secondary bladder neck obstruction in patients with urethral valves: Treatment with phenoxybenzamine ( McGuire, EJ; Weiss, RM, 1975)
"Forty-three children with overt neurological disease and neuropathic vesicourethral dysfunction were entered into a trial comparing clean intermittent catheterisation (CIC) with manual expression combined with drug treatment (non-CIC)."2.65Neuropathic vesicourethral dysfunction in children. A trial comparing clean intermittent catheterisation with manual expression combined with drug treatment. ( Borzyskowski, M; Chantler, C; Haycock, GB; Joyce, MR; Kinder, CH; Mundy, AR; Neville, BG; Park, L, 1982)
"Dicyclomine hydrochloride was the drug of choice for detrusor hyperreflexia, bethanechol chloride for hypotonicity, dantrolene sodium for somatic dyssynergia and phenoxybenzamine hydrochloride for sympathetic dyssynergia."1.26Dysfunction of the detrusor and urethra in multiple sclerosis: the role of drug therapy. ( Awad, SA; Fenemore, J; Kiruluta, HG; Wilson, JW, 1982)
"Treatment of patients with suspected bladder neck obstruction with this agent provides a reversible method of decreasing urethral resistance without the potentially harmful effects of surgical bladder neck revision."1.25Secondary bladder neck obstruction in patients with urethral valves: Treatment with phenoxybenzamine ( McGuire, EJ; Weiss, RM, 1975)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Awad, SA2
Wilson, JW1
Fenemore, J1
Kiruluta, HG2
Borzyskowski, M1
Mundy, AR1
Neville, BG1
Park, L1
Kinder, CH1
Joyce, MR1
Chantler, C1
Haycock, GB1
Downie, JW1
Raz, S1
Smith, RB1
McGuire, EJ1
Weiss, RM1
Khanna, OP1
Gonick, P1
Stephenson, TP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Botulinum Toxin Urethral Sphincter Injection for Dysfunctional Voiding - A Multicenter Study, Randomized, Double-Blind, Placebo Control[NCT01733290]Phase 270 participants (Actual)Interventional2012-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phenoxybenzamine and Urethral Diseases

ArticleYear
Pharmacologic treatment of disorders of bladder and urethra: a review.
    Canadian journal of surgery. Journal canadien de chirurgie, 1979, Volume: 22, Issue:6

    Topics: Adrenergic alpha-Agonists; Bethanechol Compounds; Female; Humans; Male; Parasympatholytics; Phenoxyb

1979

Trials

1 trial available for phenoxybenzamine and Urethral Diseases

ArticleYear
Neuropathic vesicourethral dysfunction in children. A trial comparing clean intermittent catheterisation with manual expression combined with drug treatment.
    British journal of urology, 1982, Volume: 54, Issue:6

    Topics: Bethanechol Compounds; Child; Clinical Trials as Topic; Ephedrine; Follow-Up Studies; Humans; Phenox

1982

Other Studies

5 other studies available for phenoxybenzamine and Urethral Diseases

ArticleYear
Dysfunction of the detrusor and urethra in multiple sclerosis: the role of drug therapy.
    Canadian journal of surgery. Journal canadien de chirurgie, 1982, Volume: 25, Issue:3

    Topics: Adult; Bethanechol; Bethanechol Compounds; Dantrolene; Dicyclomine; Drug Evaluation; Female; Humans;

1982
External sphincter spasticity syndrome in female patients.
    The Journal of urology, 1976, Volume: 115, Issue:4

    Topics: Adult; Diazepam; Female; Humans; Male; Methyldopa; Phenoxybenzamine; Spasm; Syndrome; Urethra; Ureth

1976
Secondary bladder neck obstruction in patients with urethral valves: Treatment with phenoxybenzamine
    Urology, 1975, Volume: 5, Issue:6

    Topics: Dilatation; Electrocoagulation; Electrosurgery; Humans; Infant; Male; Phenoxybenzamine; Postoperativ

1975
Effects of phenoxybenzamine hydrochloride on canine lower urinary tract: clinical implications.
    Urology, 1975, Volume: 6, Issue:3

    Topics: Adult; Animals; Atropine; Bethanechol Compounds; Blood Pressure; Dogs; Drug Interactions; Drug Thera

1975
Urethral dysfunction in upper motor neurone lesions.
    Clinical science (London, England : 1979), 1986, Volume: 70 Suppl 14

    Topics: Electromyography; Humans; Male; Motor Neurons; Neuromuscular Diseases; Phenoxybenzamine; Spinal Cord

1986