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phenoxybenzamine and Pyrexia

phenoxybenzamine has been researched along with Pyrexia in 17 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Research Excerpts

ExcerptRelevanceReference
"In the rabbit, intracerebroventricular administration of dibutyryl cyclic AMP (DBC) produces fever which is selectively antagonised by phenoxybenzamine."3.66Central effect of dibutyryl cyclic AMP on the temperature in the conscious rabbit. ( Kandasamy, SB, 1980)
"Fever was continuously recorded and 24 h after induction acute phase reactant (APR) response was measured as indicated by the rise of alpha-macrofetoprotein (alpha M FP, alpha 2 macroglobulin of the rat)."1.27Fever and acute phase reactants in the rat. ( Deutz, NE; van Gool, J; van Vugt, H, 1988)
" After adrenalectomy, neither 5 mg/kg nor chronic administration of 20 mg/kg morphine produced previously demonstrated hyperthermia."1.26Bole of adrenals in morphine-induced hyperthermia in restrained rats. ( Wallenstein, MC, 1982)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199016 (94.12)18.7374
1990's1 (5.88)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WOLF, HH1
GEORGE, DJ1
Kandasamy, SB3
Williams, BA1
Wallenstein, MC1
Duncan, AW1
Tibballs, J1
Sutherland, SK1
Shimomura, K1
Tomoi, M1
Mori, J1
Brick, J1
Pohorecky, LA1
Saxena, PN1
Raza, SS1
Attri, A1
Agarwal, R1
Gupta, S1
Saksena, M1
van Vugt, H1
van Gool, J1
Deutz, NE1
Junnarkar, AY1
Singh, PP1
Vezina, P1
Stewart, J1
Simmons, AV1
Carr, D1
Ross, EJ1
Tokumaru, T1
Jori, A1
Paglialunga, S1
Garattini, S1
Dixit, KS2
Dhasmana, KM2
Sinha, JN2
Bhargava, KP2

Other Studies

17 other studies available for phenoxybenzamine and Pyrexia

ArticleYear
DRUG-INDUCED HYPERTHERMIA AND AMPHETAMINE TOXICITY.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Amphetamine; Amphetamines; Aspirin; Chlorpromazine; Fever; Hyperthermia, Induced; Mice; Pharmacology

1964
Central effect of dibutyryl cyclic AMP on the temperature in the conscious rabbit.
    Pharmacology, 1980, Volume: 20, Issue:6

    Topics: Animals; Body Temperature; Brain; Bucladesine; Cyproheptadine; Drug Interactions; Fever; Hydroxydopa

1980
Hyperthermic responses to central injections of some peptide and non-peptide opioids in the guinea-pig.
    Neuropharmacology, 1983, Volume: 22, Issue:5

    Topics: Animals; Body Temperature; Endorphins; Fever; Guinea Pigs; Indomethacin; Iodipamide; Naloxone; Narco

1983
Bole of adrenals in morphine-induced hyperthermia in restrained rats.
    Life sciences, 1982, Apr-12, Volume: 30, Issue:15

    Topics: Adrenal Glands; Animals; Body Temperature; Female; Fever; Guanethidine; Male; Morphine; Pentolinium

1982
Effects of Sydney funnel-web spider envenomation in monkeys, and their clinical implications.
    The Medical journal of Australia, 1980, Oct-18, Volume: 2, Issue:8

    Topics: Acidosis; Acute Disease; Animals; Arrhythmias, Cardiac; Catecholamines; Cats; Dogs; Fever; Hypertens

1980
The role of caudate nucleus dopamine and cyclic AMP in the hyperpyrexia induced by LiCl plus tranylcypromine in rats.
    Japanese journal of pharmacology, 1979, Volume: 29, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Body Temperature; Caudate Nucleus; Chlorpromazine; Cyclic AMP

1979
Ethanol withdrawal: altered ambient temperature selection in rats.
    Alcoholism, clinical and experimental research, 1977, Volume: 1, Issue:3

    Topics: Amphetamine; Animals; Behavior, Animal; Body Temperature; Choice Behavior; Decision Making; Ethanol;

1977
Central effect of 5,8,11,14-eicosatetraenoic acid (arachidonic acid) on the temperature in the conscious rabbit.
    Experientia, 1977, Dec-15, Volume: 33, Issue:12

    Topics: Animals; Arachidonic Acids; Body Temperature; Cyproheptadine; Fever; Hydroxydopamines; Indomethacin;

1977
Central hyperthermic effect of arsenic in rabbits.
    The Indian journal of medical research, 1991, Volume: 94

    Topics: Animals; Arsenic; Arsenic Trioxide; Arsenicals; Aspirin; Body Temperature; Cerebral Ventricles; Dime

1991
Fever and acute phase reactants in the rat.
    British journal of experimental pathology, 1988, Volume: 69, Issue:4

    Topics: Acute-Phase Proteins; Acute-Phase Reaction; Adrenalectomy; Animals; Atenolol; Autonomic Nerve Block;

1988
Antagonism of clonidine-induced hypothermia by alpha adrenoceptor antagonists in electrically stimulated mice.
    Pharmacological research communications, 1988, Volume: 20, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Body Temperature; Clonidine; Electroshock; Fever; Male; Mice;

1988
Hyperthermia induced by morphine administration to the VTA of the rat brain: an effect dissociable from morphine-induced reward and hyperactivity.
    Life sciences, 1985, Mar-18, Volume: 36, Issue:11

    Topics: Animals; Body Temperature Regulation; Fever; Male; Metergoline; Morphine; Motor Activity; Naloxone;

1985
Case of self-poisoning with multiple antidepressant drugs.
    Lancet (London, England), 1970, Jan-31, Volume: 1, Issue:7640

    Topics: Adult; Antidepressive Agents; Blood Pressure; Cheese; Dibenzocycloheptenes; Fever; Humans; Intubatio

1970
Production of epinephrine-induced skin lesions and fever following local and systemic injections of herpes simplex and vesicular stomatitis viruses in the rabbit.
    Archiv fur die gesamte Virusforschung, 1971, Volume: 34, Issue:3

    Topics: Animals; Body Temperature; Culture Techniques; Endotoxins; Epinephrine; Escherichia coli; Female; Fe

1971
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpro

1967
Role of catecholamines in fatal hyperpyrexia induced by imipramine in MAOI treated rabbits.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 188, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Catecholamines; Chlorisondamine; Chlorpromazine; Drug Antagoni

1970
Antagonism of imipramine induced fatal hyperpyrexia in MAO inhibitor treated rabbits.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:4

    Topics: Amino Alcohols; Animals; Body Temperature; Drug Antagonism; Female; Fever; Imipramine; Male; Monoami

1969