phenoxybenzamine has been researched along with Parkinson Disease in 6 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marsden, CD | 2 |
| Foley, TH | 1 |
| Owen, DA | 1 |
| McAllister, RG | 1 |
| Nelson, SR | 1 |
| Walaszek, EJ | 1 |
| Andrews, CJ | 2 |
| Neilson, P | 1 |
| Knowles, L | 1 |
| Burke, D | 1 |
| Duvoisin, RC | 1 |
| Steg, G | 1 |
| Roos, BE | 1 |
1 review available for phenoxybenzamine and Parkinson Disease
| Article | Year |
|---|---|
Pharmacology of the central nervous system.
Topics: Abnormalities, Drug-Induced; Acetylcholine; Adrenocorticotropic Hormone; Amphetamine; Anger; Angiote | 1968 |
2 trials available for phenoxybenzamine and Parkinson Disease
| Article | Year |
|---|---|
Peripheral beta-adrenergic receptors concerned with tremor.
Topics: Adult; Arteries; Blood Circulation; Bradykinin; Catecholamines; Epinephrine; Fingers; Forearm; Human | 1967 |
Electromyographic study of the rigidospasticity of athetosis.
Topics: Adult; Athetosis; Clinical Trials as Topic; Electromyography; Evaluation Studies as Topic; Female; H | 1973 |
3 other studies available for phenoxybenzamine and Parkinson Disease
| Article | Year |
|---|---|
Quantitative study of the effect of L-dopa and phenoxybenzamine on the rigidity of Parkinson's disease.
Topics: Aged; Dihydroxyphenylalanine; Electromyography; Female; Humans; Male; Middle Aged; Muscle Contractio | 1973 |
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose | 1974 |
The effect of drugs inducing Parkinson's syndrome on muscle reflex mechanisms. A summary.
Topics: Animals; Chlorpromazine; Electrophysiology; Motor Neurons; Muscles; Parkinson Disease; Phenoxybenzam | 1965 |