phenoxybenzamine has been researched along with Neoplasms in 6 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propranolol treatment produced slight and similar effects in both normal and tumour-bearing rats." | 5.26 | Effect of phenoxybenzamine, propranolol, phenylephrine and isoproterenol on the circulation of rats bearing Guérin carcinoma. ( Debreczeni, LA; Farsang, C; Takács, L, 1980) |
| "Phenoxybenzamine was also found to have histone deacetylase inhibitory activity; histone deacetylase isoforms 5, 6, and 9 were the most sensitive to inhibition by phenoxybenzamine." | 1.48 | Anti-tumor activity of phenoxybenzamine and its inhibition of histone deacetylases. ( Inchiosa, MA, 2018) |
| "Propranolol treatment produced slight and similar effects in both normal and tumour-bearing rats." | 1.26 | Effect of phenoxybenzamine, propranolol, phenylephrine and isoproterenol on the circulation of rats bearing Guérin carcinoma. ( Debreczeni, LA; Farsang, C; Takács, L, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inchiosa, MA | 1 |
| OLSZEWSKI, A | 1 |
| HOWARD, JM | 1 |
| STRAWITZ, JG | 1 |
| ENGELMAN, K | 1 |
| MUELLER, PS | 1 |
| SJOERDSMA, A | 1 |
| DAY, M | 1 |
| STOCKBRIDGE, A | 1 |
| Debreczeni, LA | 1 |
| Farsang, C | 1 |
| Takács, L | 1 |
6 other studies available for phenoxybenzamine and Neoplasms
| Article | Year |
|---|---|
Anti-tumor activity of phenoxybenzamine and its inhibition of histone deacetylases.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Databases, Factual; Histone Deacetylase | 2018 |
Phenoxybenzamine hydrochloride.
Topics: Animals; Antihypertensive Agents; Carcinogens; Humans; Neoplasms; Phenoxybenzamine; Vasodilator Agen | 2011 |
THE USE OF SEROTONIN, CHLORPROMAZINE AND OTHER AGENTS FOR CONDITIONING HOSTS FOR TUMOR HETEROTRANSPLANTATION.
Topics: Chlorpromazine; Cortisone; Neoplasms; Neoplasms, Experimental; Phenoxybenzamine; Radiation Effects; | 1963 |
ELEVATED PLASMA FREE FATTY ACID CONCENTRATIONS IN PATIENTS WITH PHEOCHROMOCYTOMA. CHANGES WITH THERAPY AND CORRELATIONS WITH THE BASAL METABOLIC RATE.
Topics: Adolescent; Basal Metabolism; Blood Chemical Analysis; Catecholamines; Child; Fatty Acids; Fatty Aci | 1964 |
THE EFFECTS OF DRUGS ON THE UPTAKE OF AMINES BY MAST CELLS.
Topics: Amines; Animals; Chlorpromazine; Cocaine; Ethanolamines; Guanethidine; Hallucinogens; Histamine; Imi | 1964 |
Effect of phenoxybenzamine, propranolol, phenylephrine and isoproterenol on the circulation of rats bearing Guérin carcinoma.
Topics: Animals; Axilla; Blood Circulation; Blood Pressure; Carcinoma; Cardiac Output; Humans; Hyperkinesis; | 1980 |