phenoxybenzamine has been researched along with Necrosis in 28 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of treatment with chlorpromazine (4 mg/kg) and phenoxybenzamine (1 and 5 mg/kg) on renal function and morphology after warm ischemia and contralateral nephrectomy were studied." | 7.66 | Recovery of renal function after warm ischemia. I. The effect of chlorpromazine and phenoxybenzamine. ( Birrell, C; Howden, B; Jablonski, P; Leslie, E; Marshall, VC; Rae, D; Tange, J, 1983) |
| "Intracerebral injections of kainic acid produce gross hematuria, renal cortical necrosis, and an associated high mortality." | 3.68 | Phenoxybenzamine reduces mortality associated with intracerebral injections of excitatory neurotoxins. ( Cooley, RK; Vanderwolf, CH, 1991) |
| "The effects of treatment with chlorpromazine (4 mg/kg) and phenoxybenzamine (1 and 5 mg/kg) on renal function and morphology after warm ischemia and contralateral nephrectomy were studied." | 3.66 | Recovery of renal function after warm ischemia. I. The effect of chlorpromazine and phenoxybenzamine. ( Birrell, C; Howden, B; Jablonski, P; Leslie, E; Marshall, VC; Rae, D; Tange, J, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (89.29) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FLINN, RB | 1 |
| RUBENSTEIN, B | 1 |
| RUBINSTEIN, D | 1 |
| Crook, LE | 1 |
| Rees, KR | 1 |
| Varcoe, JS | 1 |
| Müller-Berghaus, G | 2 |
| McKay, DG | 2 |
| Selye, H | 2 |
| Häggendal, J | 1 |
| Johansson, G | 1 |
| Jönsson, L | 1 |
| Thorén-Tolling, K | 1 |
| Jablonski, P | 1 |
| Howden, B | 1 |
| Leslie, E | 1 |
| Rae, D | 1 |
| Birrell, C | 1 |
| Marshall, VC | 1 |
| Tange, J | 1 |
| Wexler, MR | 1 |
| Kalisman, M | 1 |
| Yeschua, R | 1 |
| Neuman, Z | 1 |
| Finseth, F | 2 |
| Adelberg, MG | 2 |
| Rawe, SE | 1 |
| Roth, RH | 1 |
| Collins, WF | 1 |
| Fleming, JS | 1 |
| Buchanan, JO | 1 |
| Buyniski, JP | 1 |
| Zhang, C | 1 |
| Hsueh, W | 1 |
| Vanderwolf, CH | 1 |
| Cooley, RK | 1 |
| Forrest, CR | 1 |
| Pang, CY | 1 |
| Zhong, AG | 1 |
| Neligan, PC | 1 |
| Osterholm, JL | 2 |
| Tokumaru, T | 1 |
| Rohan, P | 2 |
| Lis, M | 1 |
| Kovacs, K | 1 |
| Linder, MM | 1 |
| Mathews, GJ | 1 |
| Irvin, JD | 1 |
| Calesnick, B | 1 |
| Hedeman, LS | 1 |
| Sil, R | 1 |
| Myers, MB | 1 |
| Cherry, G | 1 |
| Ho, EC | 1 |
| Moss, AJ | 1 |
| Savoie, LL | 1 |
| Delaney, JP | 1 |
| Paritzky, AZ | 1 |
2 reviews available for phenoxybenzamine and Necrosis
| Article | Year |
|---|---|
Noradrenergic mediation of traumatic spinal cord autodestruction.
Topics: Animals; Apomorphine; Carboxy-Lyases; Cats; Disulfides; Dopamine beta-Hydroxylase; Hemorrhage; Imida | 1974 |
[On the physiopathology of the consumption coagulopathy].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antigen-Antibody Reactions; Blood Coagulation | 1969 |
26 other studies available for phenoxybenzamine and Necrosis
| Article | Year |
|---|---|
THE PREVENTION OF ACTIVE TUBULAR NECROSIS IN HEMORRHAGIC SHOCK.
Topics: Dextrans; Kidney Function Tests; Kidney Tubules; Lidocaine; Mannitol; Necrosis; Phenoxybenzamine; Pr | 1964 |
THE EFFECT OF CARBON TETRACHLORIDE ON HEPATIC LIPID METABOLISM.
Topics: Acetates; Alanine Transaminase; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisonin | 1964 |
The effect of adrenalectomy on thioacetamide-induced hepatic necrosis.
Topics: Adrenal Glands; Adrenalectomy; Amides; Animals; Chemical and Drug Induced Liver Injury; Ergotamine; | 1967 |
Prevention of the generalized Shwartzman reaction in pregnant rats by alpha-adrenergic blocking agents.
Topics: Animals; Catecholamines; Dibenzylchlorethamine; Endotoxins; Female; Hemorrhage; Kidney Glomerulus; L | 1967 |
Acute cutaneous necrosis following sensitization by heterologous blood.
Topics: Acetates; Animals; Blood Group Incompatibility; Blood Transfusion; Cats; Cattle; Chlorpromazine; Cri | 1967 |
Effect of phenoxybenzamine on myocardial cell necroses and blood levels of catecholamines in pigs subjected to stress.
Topics: Animals; Cardiomyopathies; Catecholamines; Coronary Vessels; Female; Humans; Male; Necrosis; Phenoxy | 1984 |
Recovery of renal function after warm ischemia. I. The effect of chlorpromazine and phenoxybenzamine.
Topics: Animals; Chlorpromazine; Creatinine; Dose-Response Relationship, Drug; Glomerular Filtration Rate; I | 1983 |
The effect of phenoxybenzamine, phentolamine and 6-hydroxydopamine on skin flap survival in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arteriovenous Shunt, Surgical; E | 1975 |
Prevention of skin flap necrosis by a course of treatment with vasodilator drugs.
Topics: Animals; Guanethidine; Hydralazine; Isoxsuprine; Necrosis; Phenoxybenzamine; Rats; Skin; Skin Transp | 1978 |
Experimental work with isoxuprine for prevention of skin flap necrosis and for treatment of the failing flap.
Topics: Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Graft Rejection; Injections, I | 1979 |
Norepinephrine levels in experimental spinal cord trauma. Part 2: Histopathological study of hemorrhagic necrosis.
Topics: Animals; Blood Pressure; Cats; Hemorrhage; Methyltyrosines; Necrosis; Norepinephrine; Phenoxybenzami | 1977 |
The effect of a potent inhibitor of platelet aggregation, BL-3459, on adrenaline-induced myocardial necrosis in beagle dogs.
Topics: Animals; Aspirin; Blood Pressure; Disease Models, Animal; Dogs; Epinephrine; Female; Imidazoles; Mal | 1976 |
PAF-induced bowel necrosis. Effects of vasodilators.
Topics: Alprostadil; Animals; Hydralazine; Hypotension; Indazoles; Intestinal Diseases; Leukopenia; Male; Me | 1991 |
Phenoxybenzamine reduces mortality associated with intracerebral injections of excitatory neurotoxins.
Topics: Animals; Diencephalon; Hematuria; Injections; Kainic Acid; Kidney Cortex; Necrosis; Neurotoxins; Phe | 1991 |
Role of noradrenaline in the pathogenesis of skin flap ischemic necrosis in the pig.
Topics: Animals; Ischemia; Necrosis; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Skin; Surg | 1990 |
Production of epinephrine-induced skin lesions and fever following local and systemic injections of herpes simplex and vesicular stomatitis viruses in the rabbit.
Topics: Animals; Body Temperature; Culture Techniques; Endotoxins; Epinephrine; Escherichia coli; Female; Fe | 1971 |
Protection against ethanol-induced conditioned necrosis.
Topics: Animals; Cyproheptadine; Ethanol; Female; Histamine H1 Antagonists; Injections, Intraperitoneal; Inj | 1968 |
Inhibition by adrenergic blockers of hemorrhagic necrosis in the rat's heart.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Female; Heart Diseases; Hemorrha | 1970 |
An experimental study of thrombotic ulceration of the gastrointestinal mucosa.
Topics: Adrenergic alpha-Antagonists; Aminocaproates; Animals; Disseminated Intravascular Coagulation; Duode | 1971 |
Chapter 29. Anti-norepinephrine therapy against traumatic hemorrhagic necrosis of the spinal cord: preliminary report.
Topics: Animals; Bretylium Compounds; Cats; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Guan | 1973 |
Studies in experimental spinal cord trauma. 2. Comparison of treatment with steroids, low molecular weight dextran, and catecholamine blockade.
Topics: Animals; Dextrans; Disease Models, Animal; Dogs; Edema; Glucocorticoids; Haloperidol; Hypoxia; Methy | 1974 |
Enhancement of survival in devascularized pediclexs by the use of phenoxybenzamine.
Topics: Angiography; Animals; Collateral Circulation; Coloring Agents; Dimethyl Sulfoxide; Fluoresceins; Inj | 1968 |
The syndrome of "mesenteric arteritis" following surgical repair of aortic coarctation. Report of nine cases and review of the literature.
Topics: Antihypertensive Agents; Aortic Coarctation; Arteritis; Child; Child, Preschool; Female; Humans; Hyd | 1972 |
[Role of antikaliuretics and catecholamines in the prevention of cardiac necroses of metabolic origin].
Topics: Adrenal Cortex Hormones; Amiloride; Animals; Catecholamines; Digitoxin; Diuretics; Epinephrine; Hear | 1971 |
Prevention of the acute conditioned necrosis phenomenon.
Topics: Animals; Conditioning, Classical; Cyproheptadine; Histamine; Necrosis; Phenoxybenzamine; Polysacchar | 1966 |
Necrosis of a pheochromocytoma with shock.
Topics: Adrenal Gland Neoplasms; Adult; Catecholamines; Female; Humans; Hypertension; Hypotension; Necrosis; | 1969 |