phenoxybenzamine has been researched along with Mydriasis in 4 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Mydriasis: Dilation of pupils to greater than 6 mm combined with failure of the pupils to constrict when stimulated with light. This condition may occur due to injury of the pupillary fibers in the oculomotor nerve, in acute angle-closure glaucoma, and in ADIE SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The clonidine mydriasis model in rats has been widely applied in preclinical research to characterize alpha(2)-adrenoceptor antagonistic properties of drugs." | 7.73 | Rat clonidine mydriasis model: imidazoline receptors are not involved. ( Koss, MC; Yu, Y, 2005) |
| "The clonidine mydriasis model in rats has been widely applied in preclinical research to characterize alpha(2)-adrenoceptor antagonistic properties of drugs." | 3.73 | Rat clonidine mydriasis model: imidazoline receptors are not involved. ( Koss, MC; Yu, Y, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, Y | 4 |
| Koss, MC | 4 |
4 other studies available for phenoxybenzamine and Mydriasis
| Article | Year |
|---|---|
Functional characterization of alpha-adrenoceptors mediating pupillary dilation in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Animals; Dioxanes; Dose-Response Relationship, Drug | 2003 |
Studies of alpha-adrenoceptor antagonists on sympathetic mydriasis in rabbits.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-A | 2003 |
Rat clonidine mydriasis model: imidazoline receptors are not involved.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Disease Models, Animal; | 2005 |
Alpha2-adrenoceptors do not mediate reflex mydriasis in rabbits.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Dopamine | 2004 |