phenoxybenzamine has been researched along with Muscle Relaxation in 25 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In phenoxybenzamine-pretreated preparations, Sgd 101/75 (400 microM) did not antagonise NA (maximal effect and EC50 values not changed significantly), so it was concluded that Sgd 101/75 and NA interact with different alpha 1-adrenoceptor subtypes in this tissue." | 2.36 | Sgd 101/75: a sympathomimetic that can be used to identify a new subtype of alpha-adrenoceptor, the alpha 1s-adrenoceptor. ( Chadwick, MA; Coates, J; Ismail, S; Jahn, U; Lawson, K; Thiele, K; Turner, N; Weetman, DF, 1983) |
| "A review of the management of neurogenic bladder dysfunction in the adult is presented." | 2.35 | Management of neurogenic bladder dysfunction in the adult. ( Benson, GS; Raezer, DM; Wein, AJ, 1976) |
| " Propranolol also shifted the dose-response curves to the right, but was apparently more potent in preparations with basal tone than in tissues where high tone was induced by carbachol or K+." | 1.27 | Noradrenergic and non-noradrenergic relaxation at basal and high tone levels in the guinea-pig tracheal smooth muscle. ( Abe, M; Furukawa, T, 1986) |
| " The dose-response curves for isoprenaline were shifted to the right on treatment with practolol." | 1.26 | Distribution and characterization of the adrenoceptors in dog coronary arteries. ( Morishita, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (84.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Woodman, OL | 1 |
| Missen, MA | 1 |
| Boujaoude, M | 1 |
| Weetman, DF | 1 |
| Jahn, U | 1 |
| Ismail, S | 1 |
| Chadwick, MA | 1 |
| Coates, J | 1 |
| Lawson, K | 1 |
| Turner, N | 1 |
| Thiele, K | 1 |
| Ohlstein, EH | 1 |
| Zabko-Potapovich, B | 1 |
| Berkowitz, BA | 1 |
| Zaagsma, J | 1 |
| van der Heijden, PJ | 1 |
| van der Schaar, MW | 1 |
| Bank, CM | 1 |
| Forster, C | 1 |
| Drew, GM | 1 |
| Hilditch, A | 1 |
| Whalley, ET | 1 |
| Prancan, A | 1 |
| Lefort, J | 1 |
| Barton, M | 1 |
| Vargaftig, BB | 1 |
| Tomita, R | 1 |
| Munakata, K | 1 |
| Aoki, N | 1 |
| Tanjoh, K | 1 |
| Kurosu, Y | 1 |
| Norel, X | 1 |
| Walch, L | 1 |
| Costantino, M | 1 |
| Labat, C | 1 |
| Gorenne, I | 1 |
| Dulmet, E | 1 |
| Rossi, F | 1 |
| Brink, C | 1 |
| Takewaki, T | 1 |
| Ohashi, H | 1 |
| Okada, T | 1 |
| Eccles, R | 1 |
| MacLean, AG | 1 |
| Tonoue, T | 1 |
| Furukawa, K | 1 |
| Nomoto, T | 1 |
| Baysal, F | 1 |
| Onder, S | 1 |
| Ozgül, M | 1 |
| Toygar, A | 1 |
| Morishita, H | 1 |
| Ueda, S | 1 |
| Ikegami, K | 1 |
| Sakanashi, M | 1 |
| Yonemura, KI | 1 |
| Wein, AJ | 1 |
| Raezer, DM | 1 |
| Benson, GS | 1 |
| Jacob, LS | 1 |
| Tallarida, RJ | 1 |
| Mawby, DI | 1 |
| Meric, SM | 1 |
| Crichlow, EC | 1 |
| Papich, MG | 1 |
| Asano, M | 1 |
| Masuzawa, K | 1 |
| Matsuda, T | 1 |
| Shibata, S | 1 |
| Satake, N | 1 |
| Hester, RK | 1 |
| Ramagopal, MV | 1 |
| Leighton, HJ | 1 |
| Naline, E | 1 |
| Advenier, C | 1 |
| Matran, R | 1 |
| Bakdach, H | 1 |
| Toty, L | 1 |
| Nakamura, S | 1 |
| Kohli, JD | 1 |
| Rajfer, SI | 1 |
| Ikezono, K | 1 |
| Zerkowski, HR | 1 |
| Beckeringh, JJ | 1 |
| Michel, MC | 1 |
| Brodde, OE | 1 |
| Kubota, E | 1 |
| Sata, T | 1 |
| Soas, AH | 1 |
| Paul, S | 1 |
| Said, SI | 1 |
| Abe, M | 1 |
| Furukawa, T | 1 |
2 reviews available for phenoxybenzamine and Muscle Relaxation
| Article | Year |
|---|---|
Sgd 101/75: a sympathomimetic that can be used to identify a new subtype of alpha-adrenoceptor, the alpha 1s-adrenoceptor.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Electric Stimulation; Hemodynamics; Humans; Muscle Co | 1983 |
Management of neurogenic bladder dysfunction in the adult.
Topics: Autonomic Nerve Block; Bethanechol Compounds; Dilatation; Electric Stimulation; Humans; Male; Muscle | 1976 |
23 other studies available for phenoxybenzamine and Muscle Relaxation
| Article | Year |
|---|---|
Daidzein and 17 beta-estradiol enhance nitric oxide synthase activity associated with an increase in calmodulin and a decrease in caveolin-1.
Topics: Acetylcholine; Animals; Aorta; Body Weight; Calmodulin; Caveolin 1; Caveolins; Cyclic GMP; Drug Syne | 2004 |
Studies on vascular dopamine receptors with the dopamine receptor agonist: SK&F 82526.
Topics: Animals; Benzazepines; Dinoprost; Endothelium; Fenoldopam; In Vitro Techniques; Male; Muscle Relaxat | 1984 |
Differentiation of functional adrenoceptors in human and guinea pig airways.
Topics: Anaphylaxis; Animals; Bronchi; Corticosterone; Guinea Pigs; Histamine Release; Humans; Immunization; | 1984 |
Dopamine receptors in human basilar arteries.
Topics: Basilar Artery; Dinoprost; Dopamine; Drug Interactions; Humans; In Vitro Techniques; Muscle Relaxati | 1983 |
Relaxation of the guinea-pig trachea induced by platelet-activating factor and by serotonin.
Topics: Acetylcholine; Animals; Aspirin; Blood Platelets; Female; Guinea Pigs; Histamine; In Vitro Technique | 1982 |
A study on the peptidergic nerves (VIP, substance P) in the colon of patients with diverticular disease.
Topics: Atropine; Colon; Diverticulitis, Colonic; Electric Stimulation; Humans; In Vitro Techniques; Muscle | 1993 |
M1 and M3 muscarinic receptors in human pulmonary arteries.
Topics: Acetylcholine; Cholinergic Agonists; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Humans; In Vitro | 1996 |
Non-cholinergic and non-adrenergic mechanisms in the contraction and relaxation of the chicken rectum.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Chicken | 1977 |
Relaxation of smooth muscle following contraction elicited by sympathetic nerve stimulation in vivo.
Topics: Animals; Cats; Cocaine; Desipramine; Electric Stimulation; Female; Male; Methods; Muscle Contraction | 1977 |
The direct influence of thyrotropin-releasing hormone (TRH) on the smooth muscle of rat duodenum.
Topics: Animals; Bucladesine; Duodenum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle | 1979 |
The effect of potassium on frog stomach muscle.
Topics: Animals; Anura; Biological Transport, Active; Muscle Contraction; Muscle Relaxation; Ouabain; Papave | 1979 |
Distribution and characterization of the adrenoceptors in dog coronary arteries.
Topics: Animals; Coronary Vessels; Dogs; Epinephrine; Female; Isoproterenol; Male; Muscle Relaxation; Muscle | 1979 |
Effects of prostaglandin E1 on isolated dog renal artery.
Topics: Animals; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproteren | 1979 |
Further studies on the action of ultraviolet light on vascular smooth muscle: effect of partial irreversible receptor blockade.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Calcium; Female; In Vitro Techniques; Muscle Contraction; | 1977 |
Pharmacological relaxation of the urethra in male cats: a study of the effects of phenoxybenzamine, diazepam, nifedipine and xylazine.
Topics: Administration, Oral; Animals; Cats; Diazepam; Injections, Intravenous; Male; Muscle Relaxation; Mus | 1991 |
Evidence for reduced beta-adrenoceptor coupling to adenylate cyclase in femoral arteries from spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bucladesine; Colforsin; Femoral Artery; Hyp | 1988 |
Differential inhibitory effects of nitroglycerin on contractile responses to the alpha-adrenoceptor agonists, methoxamine and clonidine, in rabbit aorta.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Radioisotopes; Clonidine; Egtazic Acid; In Vitr | 1989 |
Analysis of the presence of postjunctional alpha-2 adrenoceptors in the rat anococcygeus muscle.
Topics: Animals; Clonidine; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Muscle Cont | 1989 |
Effects of noradrenaline on the isolated human bronchus. Comparison with the isolated guinea pig trachea.
Topics: Animals; Bronchi; Cocaine; Guinea Pigs; Humans; In Vitro Techniques; Male; Muscle Relaxation; Norepi | 1988 |
Alpha-adrenoceptor blocking activity of fenoldopam (SK&F 82526), a selective DA1 agonist.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Benzazepines; Dinoprost; Dogs; Female; Fenol | 1986 |
Beta-2 adrenoceptor-mediated relaxation of the isolated human saphenous vein.
Topics: Bisoprolol; Ethanolamines; Female; Humans; In Vitro Techniques; Male; Mathematics; Muscle Relaxation | 1987 |
Vasoactive intestinal peptide as a possible transmitter of nonadrenergic, noncholinergic relaxation of pulmonary artery.
Topics: Acetylcholine; Animals; Electric Stimulation; Epinephrine; Female; Guinea Pigs; In Vitro Techniques; | 1985 |
Noradrenergic and non-noradrenergic relaxation at basal and high tone levels in the guinea-pig tracheal smooth muscle.
Topics: Animals; Carbachol; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Isometric Contra | 1986 |