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phenoxybenzamine and Ischemic Attack, Transient

phenoxybenzamine has been researched along with Ischemic Attack, Transient in 25 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
"Interestingly, transient ischemic attacks have not been documented to occur synchronously with timolol-related arrhythmias."5.27Transient ischemic attacks and amaurosis fugax from timolol. ( Coppeto, JR, 1985)
"Prazosin was given intravenously."1.27[Experimental cerebral vasospasm induced by oxyhemoglobin and the sympathetic nervous system (Part 1): Effect of alpha-adrenergic receptor blockers]. ( Endo, S; Iwai, R; Kamiyama, K; Otsuji, T; Sugita, T; Takaku, A, 1988)
"Interestingly, transient ischemic attacks have not been documented to occur synchronously with timolol-related arrhythmias."1.27Transient ischemic attacks and amaurosis fugax from timolol. ( Coppeto, JR, 1985)
" Intravenous use, however, was ineffective in the dosage with which total systemic alpha adrenergic blockade was obtained."1.25Effect of phenoxybenzamine on experimental cerebral arterial spasm in cats. ( Handa, H; Handa, J; Koyama, T; Matsuda, M; Yoneda, S, 1975)
"Phenoxybenzamine was found to be effective in reversing and preventing these contractions."1.25Chronic cerebral arterial spasm. The role of intracranial pressure. ( Farrar, JK, 1975)
" Intravenous administration of PBZ in the dosage with which the pressor response to phenylephrine was completely blocked, or three times that dosage, failed to show any preventive effect on the vasospasm."1.25[Effect of phenoxybenzamine on the experimental cerebral vasospasm in cats (author's transl)]. ( Handa, H; Handa, J; Koyama, T; Matsuda, M; Yoneda, S, 1975)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199025 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, TJ1
McIlhany, MP1
Sarwinski, S1
Kostron, H1
Twerdy, K1
Mohsenipour, I1
Fischer, J1
Cameron, MM1
Haas, RH1
Morooka, H1
White, RP3
Huang, SP1
Hagen, AA1
Robertson, JT2
Handa, J3
Yoneda, S2
Matsuda, M4
Koyama, T2
Handa, H3
Farrar, JK1
Odom, GL1
Iwai, R2
Kamiyama, K2
Nagahori, T1
Ohtsuji, T1
Endo, S2
Takaku, A2
Otsuji, T1
Sugita, T1
Coppeto, JR1
Martins, AN1
Wiley, JK1
Fraser, RA1
Stein, BM1
Barrett, RE1
Pool, JL1
Flamm, ES1
Yasargil, MG1
Ransohoff, J1
Smigiel, MR1
Sundt, TM1
Hashi, K1
Meyer, JS2
Shinmaru, S1
Welch, KM1
Teraura, T1
Otsubo, K1
Shimazu, K1
Okamoto, S1
Koto, A1
Ito, Y1
Sari, A1
Ericsson, AD1
Dawson, WN1
Allen, GS2
Henderson, LM1
Chou, SN2
French, LA2
Gold, LH1
Heaton, JA1
Denton, IC1

Reviews

1 review available for phenoxybenzamine and Ischemic Attack, Transient

ArticleYear
Cerebral vasodilators.
    British medical journal, 1971, Jun-19, Volume: 2, Issue:5763

    Topics: Aged; Alcohols; Blood Pressure; Carbon Dioxide; Cerebral Arterial Diseases; Cerebrovascular Circulat

1971

Trials

1 trial available for phenoxybenzamine and Ischemic Attack, Transient

ArticleYear
Adrenergic blockade in subarachnoid haemorrhage.
    Acta neurochirurgica, 1976, Volume: 34, Issue:1-4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Humans; Ischemic Attack, Transient; Pheno

1976

Other Studies

23 other studies available for phenoxybenzamine and Ischemic Attack, Transient

ArticleYear
Erythrocyte extracts enhance neurogenic vasoconstriction of dog cerebral arteries in vitro.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1984, Volume: 4, Issue:3

    Topics: Animals; Cerebral Arteries; Dogs; Electric Stimulation; Erythrocytes; Female; In Vitro Techniques; I

1984
[Cerebral vasospasm: clinical and biochemical aspects and treatment (author's transl)].
    Neurochirurgia, 1981, Volume: 24, Issue:1

    Topics: Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Norepinephrine; Papaverine; Phenoxybenzam

1981
Cerebral arterial spasm. II. Etiology and treatment of experimental cerebral vasospasm.
    Acta medica Okayama, 1978, Volume: 32, Issue:1

    Topics: Albuterol; Animals; Ascorbic Acid; Basilar Artery; Catalase; Cats; Dopamine; Dopamine beta-Hydroxyla

1978
Experimental assessment of phenoxybenzamine in cerebral vasospasm.
    Journal of neurosurgery, 1979, Volume: 50, Issue:2

    Topics: Animals; Basilar Artery; Cerebral Angiography; Cisterna Magna; Dogs; Female; Ischemic Attack, Transi

1979
Effect of phenoxybenzamine on experimental cerebral arterial spasm in cats.
    Surgical neurology, 1975, Volume: 3, Issue:2

    Topics: Administration, Topical; Animals; Blood Pressure; Cats; Disease Models, Animal; Female; Injections,

1975
Chronic cerebral arterial spasm. The role of intracranial pressure.
    Journal of neurosurgery, 1975, Volume: 43, Issue:4

    Topics: Animals; Cerebrovascular Circulation; Chronic Disease; Constriction, Pathologic; Epinephrine; Intrac

1975
Cerebral vasospasm.
    Clinical neurosurgery, 1975, Volume: 22

    Topics: Adolescent; Adult; Brain; Cerebrovascular Circulation; Female; Humans; Intracranial Aneurysm; Ischem

1975
[Effect of phenoxybenzamine on the experimental cerebral vasospasm in cats (author's transl)].
    No shinkei geka. Neurological surgery, 1975, Volume: 3, Issue:7

    Topics: Animals; Basilar Artery; Blood Pressure; Blood Transfusion, Autologous; Cats; Female; Ischemic Attac

1975
Relation of supersensitivity to cerebral vasospasm induced by oxyhaemoglobin.
    Neurological research, 1988, Volume: 10, Issue:3

    Topics: Animals; Basilar Artery; Cats; Ganglia, Sympathetic; Ischemic Attack, Transient; Oxyhemoglobins; Phe

1988
[Experimental cerebral vasospasm induced by oxyhemoglobin and the sympathetic nervous system (Part 1): Effect of alpha-adrenergic receptor blockers].
    No to shinkei = Brain and nerve, 1988, Volume: 40, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Cats; Cerebrovascular Circulation; Dinoprost; Ischemic Attack

1988
Transient ischemic attacks and amaurosis fugax from timolol.
    Annals of ophthalmology, 1985, Volume: 17, Issue:1

    Topics: Aged; Arrhythmias, Cardiac; Blindness; Humans; Ischemic Attack, Transient; Male; Phenoxybenzamine; T

1985
Side effects of spasmolytic agents in the monkey. Intracisternal phenoxybenzamine and phentolamine.
    Journal of neurosurgery, 1973, Volume: 39, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Electroencephalography; Haplorhini; Hypotension; Injectio

1973
Noradrenergic mediation of experimental cerebrovascular spasm.
    Transactions of the American Neurological Association, 1970, Volume: 95

    Topics: Adrenergic alpha-Antagonists; Animals; Basilar Artery; Bretylium Compounds; Haplorhini; Ischemic Att

1970
Alteration of experimental cerebral vasospasm by adrenergic blockade.
    Journal of neurosurgery, 1972, Volume: 37, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Basilar Artery; Blood Flow Velocity; Blood Pressure; Cats; Di

1972
Comparative effectiveness of alpha-blockade and beta-stimulation in modifying experimental basilar arterial spasm.
    Journal of neurosurgery, 1974, Volume: 41, Issue:3

    Topics: Animals; Basilar Artery; Cats; Drug Evaluation, Preclinical; Ischemic Attack, Transient; Isoproteren

1974
Effect of glycerol and intracarotid phenoxybenzamine on cerebral hemodynamics and metabolism after experimental subarachnoid hemorrhage.
    Journal of the neurological sciences, 1972, Volume: 17, Issue:1

    Topics: Animals; Blood Pressure; Brain Edema; Cerebrovascular Circulation; Glycerol; Haplorhini; Ischemic At

1972
Effect of intracarotid phenoxybenzamine on cerebral blood flow and vasospasm: a clinical study.
    Surgical neurology, 1973, Volume: 1, Issue:4

    Topics: Blood Pressure; Carbon Dioxide; Cerebral Angiography; Cerebrovascular Circulation; Cerebrovascular D

1973
[Experimental cerebral vasospasm].
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1973, Jan-01, Volume: 42, Issue:1

    Topics: Animals; Blood Pressure; Cats; Dibenzazepines; Electrocardiography; Electroencephalography; Female;

1973
Two separate mechanisms controlling cerebral blood flow: effect of alpha adrenergic blockade on cerebral autoregulation and chemical vasomotor control.
    Transactions of the American Neurological Association, 1973, Volume: 98

    Topics: Adult; Aged; Basilar Artery; Blood Pressure; Carbon Dioxide; Carotid Arteries; Cerebral Arteries; Ce

1973
Pharmacologic determination of the role of autonomic receptor sites in cerebral vasospasm.
    Surgical forum, 1973, Volume: 24

    Topics: Angiography; Animals; Atropine; Basilar Artery; Brain Stem; Catecholamines; Dogs; Ganglia, Autonomic

1973
Cerebral arterial spasm. 2. In vitro contractile activity of serotonin in human serum and CSF on the canine basilar artery, and its blockage by methylsergide and phenoxybenzamine.
    Journal of neurosurgery, 1974, Volume: 40, Issue:4

    Topics: Animals; Basilar Artery; Dogs; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; In Vit

1974
Cerebral arterial spasm. 3. In vivo intracisternal production of spasm by serotonin and blood and its reversal by phenoxybenzamine.
    Journal of neurosurgery, 1974, Volume: 40, Issue:4

    Topics: Animals; Basilar Artery; Cerebral Angiography; Disease Models, Animal; Dogs; Female; Ischemic Attack

1974
Pharmacological comparison of prostaglandin F 2a' serotonin and norepinephrine on cerebrovascular tone of monkey.
    European journal of pharmacology, 1971, Volume: 15, Issue:3

    Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Female; Haplorhini; Ischemic Attack, Transient

1971