phenoxybenzamine has been researched along with Ischemia in 59 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
Excerpt | Relevance | Reference |
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"The effects of treatment with chlorpromazine (4 mg/kg) and phenoxybenzamine (1 and 5 mg/kg) on renal function and morphology after warm ischemia and contralateral nephrectomy were studied." | 7.66 | Recovery of renal function after warm ischemia. I. The effect of chlorpromazine and phenoxybenzamine. ( Birrell, C; Howden, B; Jablonski, P; Leslie, E; Marshall, VC; Rae, D; Tange, J, 1983) |
", or the same dosage of phenoxybenzamine plus plasma infusion (16 ml." | 5.26 | Hemodynamic effects of phenoxybenzamine and volume replacement in segmental ischemia of the rat small intestine. ( Norlén, K; Rentzhog, L; Wikström, S, 1978) |
"The effects of treatment with chlorpromazine (4 mg/kg) and phenoxybenzamine (1 and 5 mg/kg) on renal function and morphology after warm ischemia and contralateral nephrectomy were studied." | 3.66 | Recovery of renal function after warm ischemia. I. The effect of chlorpromazine and phenoxybenzamine. ( Birrell, C; Howden, B; Jablonski, P; Leslie, E; Marshall, VC; Rae, D; Tange, J, 1983) |
"A patient with a clinical and angiographic diagnosis of nonocclusive mesenteric ischemia had phenoxybenzamine directly infused into the superior mesenteric artery to counteract the existing splanchnic vasoconstriction." | 3.65 | Vasodilatory drugs in the management of nonocclusive bowel ischemia. ( Athanasoulis, CA; Bernstein, R; Williams, LF; Wittenberg, J, 1975) |
"Cardiogenic shock was induced by pericardial tamponade." | 1.30 | Hemodynamics of pancreatic ischemia in cardiogenic shock in pigs. ( Bulkley, GB; Miyachi, M; Reilly, PM; Schiller, HJ; Toung, TJ, 1997) |
"adenosine was better (P less than 0-05) than no treatment, i." | 1.26 | Enhanced preservation of the ischaemic kidney with inosine. ( Armstrong, DM; Fernando, AR; Griffiths, JR; Hendry, WF; O'Donoghue, EP; Perrett, D; Ward, JP; Wickham, JE, 1976) |
"Pretreatment with allopurinol, dibenzyline, methylprednisolone, glucagon, ATP-MgCl2 and aspartic acid reduced the overall mortality of ischemic liver injury." | 1.26 | Ischemic damage of the liver. Part II: In vivo investigation of the prevention of the ischemic lesion of the liver. ( Kokas, P; Kupcsulik, P, 1979) |
", or the same dosage of phenoxybenzamine plus plasma infusion (16 ml." | 1.26 | Hemodynamic effects of phenoxybenzamine and volume replacement in segmental ischemia of the rat small intestine. ( Norlén, K; Rentzhog, L; Wikström, S, 1978) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 56 (94.92) | 18.7374 |
1990's | 2 (3.39) | 18.2507 |
2000's | 1 (1.69) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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FRIEND, DG | 1 |
EDWARDS, EA | 1 |
HERSHEY, SG | 1 |
BAEZ, S | 1 |
ROVENSTINE, EA | 1 |
MARTIN, K | 1 |
LILLEHEI, RC | 2 |
LONGERBEAM, JK | 1 |
BLOCH, JH | 1 |
MANAX, WG | 1 |
Swan, KG | 2 |
Jacobson, ED | 1 |
Schuldt, HH | 1 |
Oesterwitz, H | 1 |
Schröder, K | 1 |
Jablonski, P | 1 |
Howden, B | 1 |
Leslie, E | 1 |
Rae, D | 1 |
Birrell, C | 1 |
Marshall, VC | 1 |
Tange, J | 1 |
Kerrigan, CL | 1 |
Daniel, RK | 1 |
Reilly, PM | 1 |
Toung, TJ | 1 |
Miyachi, M | 1 |
Schiller, HJ | 1 |
Bulkley, GB | 2 |
Eckert, RE | 1 |
Karsten, AJ | 1 |
Utz, J | 1 |
Ziegler, M | 1 |
Welch, KM | 1 |
Meyer, JS | 1 |
Chabi, E | 1 |
Miyakawa, Y | 1 |
Itoh, Y | 1 |
Ishihara, N | 1 |
Chee, AN | 1 |
Sterling, WA | 2 |
Kirk, KA | 1 |
Turner, ME | 1 |
Fernando, AR | 1 |
Armstrong, DM | 1 |
Griffiths, JR | 1 |
Hendry, WF | 1 |
O'Donoghue, EP | 1 |
Perrett, D | 1 |
Ward, JP | 1 |
Wickham, JE | 1 |
Chatterjee, SN | 1 |
Dhabuwala, CB | 1 |
Bird, M | 1 |
Salaman, JR | 1 |
Green, RD | 1 |
Boyer, D | 1 |
Halasz, NA | 1 |
Collins, GM | 1 |
Kupcsulik, P | 1 |
Kokas, P | 1 |
Mattson, J | 1 |
Appelgren, L | 1 |
Karlsson, L | 1 |
Peterson, HI | 1 |
Spielman, WS | 1 |
Osswald, H | 1 |
Norlén, K | 1 |
Rentzhog, L | 1 |
Wikström, S | 1 |
Baur, GM | 1 |
Porter, JM | 1 |
Bardana, EJ | 1 |
Wesche, DH | 1 |
Rösch, J | 1 |
Harders, H | 1 |
Athanasoulis, CA | 1 |
Wittenberg, J | 1 |
Bernstein, R | 1 |
Williams, LF | 2 |
Wright, CB | 1 |
Hobson, RW | 1 |
Rich, NM | 1 |
Peart, WS | 1 |
Pessina, AC | 1 |
Forrest, CR | 1 |
Pang, CY | 1 |
Zhong, AG | 1 |
Neligan, PC | 1 |
Feller, SR | 1 |
Dockery, GL | 1 |
Bailey, RW | 1 |
Hamilton, SR | 1 |
Morris, JB | 1 |
Haglund, UH | 1 |
Russo, A | 2 |
Giovinetto, A | 1 |
Ippolito, O | 1 |
Di Benedetto, L | 1 |
Sanfilippo, G | 1 |
Murabito, R | 1 |
Hinshaw, LB | 1 |
Page, BB | 1 |
Brake, CM | 1 |
Emerson, TE | 1 |
Somogyi, A | 1 |
Selye, H | 1 |
Grandchamp, A | 2 |
Ayer, G | 1 |
Truniger, B | 1 |
Dempster, WJ | 1 |
Greenway, CV | 1 |
Murthy, VS | 1 |
Needleman, P | 1 |
Douglas, JR | 1 |
Jakschik, B | 1 |
Stoecklein, PB | 1 |
Johnson, EM | 1 |
Veroux, G | 1 |
Cirino, E | 1 |
Di Benedetto, A | 1 |
Russo, S | 1 |
Biondi, M | 1 |
Nicolosi, M | 1 |
Kontos, HA | 1 |
Richardson, DW | 1 |
Raper, AJ | 1 |
Patterson, JL | 1 |
Váczy, L | 1 |
Lenner, A | 1 |
Molnár, A | 1 |
Kawarada, Y | 1 |
Wolferth, CC | 1 |
Matsumoto, T | 1 |
Pryor, JP | 1 |
Braf, ZF | 1 |
Boichis, H | 1 |
Horowitz, A | 1 |
Orda, S | 1 |
Ben-David, A | 1 |
Pierce, JC | 1 |
Lee, HM | 1 |
Hume, M | 1 |
Lee, BB | 1 |
Brichta, LF | 1 |
Currier, CB | 1 |
Hasegawa, A | 1 |
Burdick, J | 1 |
Varkarakis, MJ | 1 |
Murphy, GP | 1 |
Belzer, FO | 1 |
Bell, PR | 2 |
Quin, RO | 2 |
Calman, KC | 2 |
Hopkinson, I | 1 |
Wood, RF | 1 |
Toledo-Pereyra, LH | 2 |
Moberg, AW | 2 |
Najarian, JS | 2 |
Mozes, MF | 1 |
Campos, RA | 1 |
McCabe, R | 1 |
Stevens, LE | 1 |
Subramanian, A | 1 |
Lattes, C | 1 |
Fitzpatrick, HF | 1 |
Hayase, S | 1 |
Ito, H | 1 |
Kondo, Y | 1 |
Imao, T | 1 |
Yoshimura, T | 1 |
Draz, S | 1 |
Minami, R | 1 |
Byrield, J | 1 |
Fonkalsrud, EW | 1 |
Voegeli, E | 1 |
Kabal, J | 1 |
Doyle, TF | 1 |
Nagy, Z | 1 |
Mészáros, A | 1 |
Vaslaki, L | 1 |
Anastasia, LF | 1 |
Hasiotis, CA | 1 |
Bosniak, MA | 1 |
Byrne, JJ | 1 |
Hardcastle, JD | 1 |
Ritchie, HD | 1 |
Kovách, AG | 1 |
Simon, L | 1 |
Sándor, P | 1 |
Kunos, G | 1 |
Marton, I | 1 |
Kun, E | 1 |
Linzell, JL | 1 |
Setchell, BP | 1 |
Corday, E | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Use of Nitroglycerine to Improve Signs of Poor Peripheral Perfusion in Patients With Traumatic Hemorrhagic Shock[NCT03235921] | Phase 2 | 100 participants (Anticipated) | Interventional | 2016-03-31 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for phenoxybenzamine and Ischemia
Article | Year |
---|---|
Pharmacologic agents of potential value in protecting kidneys from ischemic damage.
Topics: Adrenal Cortex Hormones; Allopurinol; Animals; Chlorpromazine; Dogs; Glutathione; Humans; Ischemia; | 1977 |
Renal preservation.
Topics: Animals; Cadaver; Cold Temperature; Cryoprotective Agents; Dogs; Freezing; Humans; Ischemia; Kidney; | 1974 |
1 trial available for phenoxybenzamine and Ischemia
Article | Year |
---|---|
Contribution of hypercapnia and hypoxia to the vascular response to ischaemia.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; B | 1970 |
56 other studies available for phenoxybenzamine and Ischemia
Article | Year |
---|---|
Use of dibenzyline as a vasodilator in patients with severe digital ischemia.
Topics: Fingers; Humans; Ischemia; Peripheral Vascular Diseases; Phenoxybenzamine; Sympatholytics; Vasodilat | 1954 |
Intestinal ischemia shock in normal and Dibenzyline-protected dogs.
Topics: Animals; Dogs; Intestines; Ischemia; Phenoxybenzamine; Shock; Sympatholytics; Vascular Diseases | 1961 |
OBSERVATIONS ON THE INCREASE IN PERMEABILITY INDUCED BY ADRENALINE IN THE SUBMAXILLARY GLAND.
Topics: Arginine Vasopressin; Blood Flow Velocity; Carbohydrate Metabolism; Cats; Cervical Plexus; Creatine; | 1964 |
THE NATURE OF IRREVERSIBLE SHOCK: EXPERIMENTAL AND CLINICAL OBSERVATIONS.
Topics: Blood Flow Velocity; Blood Pressure Determination; Blood Transfusion; Blood Volume Determination; Co | 1964 |
Hemodynamics of endotoxin shock in the conscious animal.
Topics: Anesthetics; Animals; Blood Flow Velocity; Dogs; Female; Hypertension, Portal; Hypotension; Ischemia | 1967 |
[Modification of vasoconstriction in ischemically stressed and extracorporeally perfused dog kidneys by alpha adrenergic blockade with phenoxybenzamine].
Topics: Angiography; Animals; Dogs; Ischemia; Kidney; Kidney Transplantation; Microcirculation; Nephrectomy; | 1984 |
Recovery of renal function after warm ischemia. I. The effect of chlorpromazine and phenoxybenzamine.
Topics: Animals; Chlorpromazine; Creatinine; Dose-Response Relationship, Drug; Glomerular Filtration Rate; I | 1983 |
Pharmacologic treatment of the failing skin flap.
Topics: Animals; Graft Survival; Ischemia; Isoxsuprine; Phenoxybenzamine; Regional Blood Flow; Reserpine; Sk | 1982 |
Hemodynamics of pancreatic ischemia in cardiogenic shock in pigs.
Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; C | 1997 |
Regulation of renal artery smooth muscle tone by alpha1-adrenoceptors: role of voltage-gated calcium channels and intracellular calcium stores.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channel Blockers; | 2000 |
Tyrosine uptake and neurotransmitter synthesis in ischemic brain after administration of alpha and beta adrengeric blocking agents to man.
Topics: Brain; Humans; Ischemia; Neurotransmitter Agents; Phenoxybenzamine; Propranolol; Tyrosine | 1975 |
Letter: Ischaemia times and phenoxybenzamine in human cadaver-kidney donors.
Topics: Cadaver; Cold Temperature; Humans; Ischemia; Kidney; Kidney Transplantation; Kidney Tubular Necrosis | 1975 |
Enhanced preservation of the ischaemic kidney with inosine.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Creatinine; Cyclic AMP; Inosine; Ischemia; | 1976 |
Relative importance of warm ischaemia, hypotension, and hypercarbia in producing renal vasospasm.
Topics: Animals; Blood Circulation; Blood Pressure; Female; Hot Temperature; Hypercapnia; Hypotension; Ische | 1979 |
Pharmacological protection of rabbit kidneys from normothermic ischemia.
Topics: Animals; Body Temperature; Chlorpromazine; Dopamine; Female; Furosemide; Ischemia; Kidney; Male; Man | 1979 |
Ischemic damage of the liver. Part II: In vivo investigation of the prevention of the ischemic lesion of the liver.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Aspartic Acid; Chlorides; Glucagon; Ischemia; Liver; L | 1979 |
Influence of vasoactive drugs and ischaemia on intra-tumour blood flow distribution.
Topics: Animals; Blood Pressure; Ischemia; Muscles; Neoplasms, Experimental; Norepinephrine; Phenoxybenzamin | 1978 |
Characterization of the postocclusive response of renal blood flow in the cat.
Topics: Adenosine; Angiotensin II; Animals; Blood Flow Velocity; Cats; Indomethacin; Ischemia; Kidney; Meclo | 1978 |
Hemodynamic effects of phenoxybenzamine and volume replacement in segmental ischemia of the rat small intestine.
Topics: Acid-Base Equilibrium; Animals; Blood Transfusion; Edema; Hematocrit; Hemodynamics; Intestine, Small | 1978 |
Rapid onset of hand ischemia of unknown etiology: clinical evaluation and follow-up of ten patients.
Topics: Adolescent; Adult; Angiography; Female; Follow-Up Studies; Guanethidine; Hand; Humans; Ischemia; Mal | 1977 |
[Chronic intestinal blood circulation disorders].
Topics: Anticoagulants; Chronic Disease; Collateral Circulation; Glucagon; Heart Rate; Humans; Intestines; I | 1976 |
Vasodilatory drugs in the management of nonocclusive bowel ischemia.
Topics: Aged; Female; Humans; Injections, Intra-Arterial; Intestines; Ischemia; Mesenteric Arteries; Mesente | 1975 |
Extremity venous ligation: clinical and hemodynamic correlation.
Topics: Animals; Arteriosclerosis; Blood Pressure; Dogs; Evaluation Studies as Topic; Femoral Artery; Femora | 1975 |
The mechanism of acute renal ischaemia caused by adrenalectomy in the rat.
Topics: Adrenalectomy; Animals; Aorta; Blood Pressure; Central Venous Pressure; Denervation; Glomerular Filt | 1975 |
Role of noradrenaline in the pathogenesis of skin flap ischemic necrosis in the pig.
Topics: Animals; Ischemia; Necrosis; Norepinephrine; Phenoxybenzamine; Phentolamine; Propranolol; Skin; Surg | 1990 |
Vasospastic diseases. Diagnosis and management.
Topics: Calcium Channel Blockers; Cold Temperature; Cyanosis; Foot Diseases; Frostbite; Humans; Ischemia; Ph | 1986 |
Protection of the small intestine from nonocclusive mesenteric ischemic injury due to cardiogenic shock.
Topics: Animals; Cardiac Output; Cardiac Tamponade; Intestinal Mucosa; Intestine, Small; Ischemia; Phenoxybe | 1987 |
[Effect of selective deep hypothermia, isolated or associated with alpha adrenergic receptor block, on ischemic renal transplants].
Topics: Adrenergic alpha-Antagonists; Animals; Creatinine; Dogs; Female; Hypothermia, Induced; Ischemia; Kid | 1973 |
Mechanisms of intrarenal hemodynamic changes following acute arterial occlusion.
Topics: Angiotensin II; Animals; Blood Pressure; Diphenhydramine; Dogs; Epinephrine; Hemodynamics; Histamine | 1963 |
Tourniquet poditis--an experimental pedal inflammation in the rat.
Topics: Animals; Anti-Bacterial Agents; Chlorpromazine; Cyproheptadine; Depression, Chemical; Dextrans; Dibe | 1969 |
Pathogenesis of redistribution of intrarenal blood flow in haemorrhagic hypotension.
Topics: Acetylcholine; Angiotensin II; Animals; Autoradiography; Blood Flow Velocity; Dogs; Hypotension; Isc | 1971 |
The nature of experimental second-set kidney transplant rejection. 2. The mimicking of the haemodynamic upset by pharmacological and other means.
Topics: Angiography; Angiotensin II; Animals; Dogs; Ergolines; Ergonovine; Female; Graft Rejection; Hemodyna | 1971 |
Mesenteric vasoconstriction after endotoxin administration in cats pretreated with aspirin.
Topics: Angiotensin II; Animals; Aspirin; Blood Platelets; Blood Pressure; Cats; Endotoxins; Heart Failure; | 1971 |
Release of renal prostaglandin by catecholamines: relationship to renal endocrine function.
Topics: Angiotensin II; Animals; Aorta; Catecholamines; Dopamine; Electric Stimulation; Endocrine Glands; Ep | 1974 |
[Research on the prevention of renal anatomo-functional damage due to temporary occlusion of the subrenal aorta. II. Action of alpha-adrenergic blocking agents in local intra-arterial administration].
Topics: Adrenergic alpha-Antagonists; Animals; Aortic Diseases; Dogs; Injections, Intra-Arterial; Ischemia; | 1968 |
Treatment of pregnancy toxaemia with alpha-blocking agents.
Topics: Adrenergic alpha-Antagonists; Adult; Brain; Capillary Permeability; Eclampsia; Female; Humans; Hyper | 1971 |
Phenoxybenzamine and steroid in renal microcirculation in endotoxin shock. 1.
Topics: Acute Kidney Injury; Angiography; Animals; Dexamethasone; Dogs; Escherichia coli; Female; Ischemia; | 1972 |
Some methods of improving the immediate function of cadaver kidneys after transplantation.
Topics: Adrenalectomy; Angiography; Animals; Anuria; Bicarbonates; Blood Vessels; Cadaver; Constriction; Hum | 1972 |
Phenoxybenzamine in kidney preservation for transplantation.
Topics: Animals; Dogs; Electrolytes; Injections, Intra-Arterial; Ischemia; Kidney Transplantation; Perfusion | 1972 |
Comparison of methods of preservation of cadaver kidneys.
Topics: Cadaver; Humans; Ischemia; Kidney; Kidney Transplantation; Perfusion; Phenoxybenzamine; Tissue Donor | 1972 |
Evaluation of renal flow distribution in stored kidneys.
Topics: Animals; Dogs; Female; Freezing; Hemodynamics; Hydrogen-Ion Concentration; Ice; Ischemia; Kidney; Ki | 1973 |
Donor pretreatment and organ preservation.
Topics: Animals; Chlorpromazine; Coronary Vessels; Furosemide; Heart Transplantation; Heparin; Ischemia; Kid | 1974 |
Hyperbaric hypothermic perfusion preservation of ischaemic kidneys.
Topics: Animals; Cold Temperature; Dextrans; Dogs; Hyperbaric Oxygenation; Ischemia; Kidney; Kidney Transpla | 1973 |
Optimal management of warm ischemic kidneys prior to hypothermic preservation.
Topics: Allopurinol; Animals; Cadaver; Cold Temperature; Diuretics; Dogs; Humans; Ischemia; Kidney; Kidney T | 1974 |
Prevention of irreversible ischemic damage in renal preservation by pharmacological manipulation.
Topics: Allopurinol; Animals; Chlorpromazine; Dogs; Hypothermia; Ischemia; Kidney Transplantation; Methylpre | 1974 |
The importance of donor protection by furosemide and steroids in cadaveric kidney preservation.
Topics: Cadaver; Cold Temperature; Furosemide; Graft Rejection; Humans; Ischemia; Kidney Transplantation; Ki | 1973 |
Inhibitory action of propranolol and its stereoisomers on epinephrine-induced changes in electrocardiogram.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Electrocardiography; Epinephrine; Female; Ische | 1972 |
Biochemical evaluation of hepatic preservation techniques in the isolated rat liver.
Topics: Acid Phosphatase; Acid-Base Equilibrium; Alanine Transaminase; Animals; Buffers; Chlorpromazine; Glu | 1971 |
[The cortical renal ischaemia. The angiographic diagnosis and clinical meaning].
Topics: Adrenal Glands; Angiography; Animals; Dogs; Epinephrine; Humans; Ischemia; Kidney; Kidney Diseases; | 1971 |
The origin of tourniquet shock-induced cardiovascular failure in exogenous hyperthyroidism.
Topics: Animals; Extremities; Heart; Hemodynamics; Hyperthyroidism; Ischemia; Male; Phenoxybenzamine; Rats; | 1971 |
Arterio-venous anastomoses in the kidney. X. Effect of phenoxybenzamine on intrarenal circulation of dogs in tourniquet shock.
Topics: Animals; Arteriovenous Anastomosis; Blood Flow Velocity; Blood Pressure; Cardiac Output; Dogs; Injec | 1971 |
Experimental nonocclusive mesenteric ischemia. Therapeutic observations.
Topics: Animals; Carbon Dioxide; Dextrans; Dogs; Enteritis; Femoral Artery; Hydrogen-Ion Concentration; Isch | 1968 |
The liver in shock. A comparison of some techniques used currently in therapy.
Topics: Animals; Blood Glucose; Dogs; Epinephrine; Hepatic Veins; Hypertonic Solutions; Hypothermia, Induced | 1968 |
[Studies on the effect of 2-ethyl-3,3-diphenyl propen-(2)-yl-amine in experimental hemorrhagic and ischemic shock].
Topics: Animals; Arteries; Blood Pressure; Blood Volume; Butylamines; Dogs; Female; Ischemia; Male; Phenoxyb | 1968 |
Metabolism, sperm and fluid production of the isolated perfused testis of the sheep and goat.
Topics: Animals; Blood Glucose; Electric Stimulation; Epinephrine; Goats; Heparin; In Vitro Techniques; Isch | 1969 |
Pressor agents in cardiogenic shock.
Topics: Animals; Anuria; Aortic Valve; Blood Flow Velocity; Blood Pressure; Blood Viscosity; Blood Volume; C | 1969 |