phenoxybenzamine has been researched along with Intraocular Pressure in 25 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A study has been made of the time courses of the pupillary and intraocular pressure responses of conscious rabbits to clonidine administered either topically or intravenously." | 7.65 | The intraocular pressure response of conscious rabbits to clonidine. ( Allen, RC; Langham, ME, 1976) |
| "We have extended our previous observations on the effect of tranylcypromine (TCP) on intraocular pressure (IOP), following topical administration of catecholamines is normal and chemically denervated rabbit eyes." | 3.66 | Does prostacyclin mediate alpha-adrenergic induced hypotension? ( Haddeman, E; Hoyng, PF; van Alphen, GW, 1982) |
| " Both alpha- and beta-adrenergic antagonists (alpha-antagonists, phentolamine and phenoxybenzamine; beta-antagonists, propranolol and sotalol) cuased a dose-dependent reduction in intraocular pressure and blood pressure and increased total outflow facility." | 3.65 | Interaction of adrenergic antagonists with prostaglandin E2 and tetrahydrocannabinol in the eye. ( Green, K; Kim, K, 1976) |
| "A study has been made of the time courses of the pupillary and intraocular pressure responses of conscious rabbits to clonidine administered either topically or intravenously." | 3.65 | The intraocular pressure response of conscious rabbits to clonidine. ( Allen, RC; Langham, ME, 1976) |
| "In rabbits the topical administration of sodium azide (NaNs) or sodium nitroprusside (SNP) increased intraocular pressure in a dose-response manner." | 1.26 | Increased intraocular pressure following topical azide or nitroprusside. ( Becker, B; Fritz, C; Holmberg, N; Krupin, T; Weiss, A, 1977) |
| "Labetalol has a unique and profound effect on the IOP of rabbits, in contrast to pure beta-adrenergic blockers which have little or no effect in this animal." | 1.26 | Ocular hypotensive action of labetalol. ( Leopold, IH; Murray, DL, 1979) |
| "The indomethacin pretreatment had no effect on pupil size of any group, but phenoxybenzamine (PBA) reduced the mydriatic effect, implying a direct or a predominant role of NE on iris muscle." | 1.26 | Effects of prostaglandins and norepinephrine on ocular pressure and pupil size in rabbits following bilateral cervical ganglionectomy. ( Cheek, WV; Waitzman, MB; Woods, WD, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SEARS, ML | 2 |
| SHERK, TE | 1 |
| Hoyng, PF | 1 |
| van Alphen, GW | 1 |
| Haddeman, E | 1 |
| Green, K | 3 |
| Elijah, D | 1 |
| Kim, K | 2 |
| Allen, RC | 1 |
| Langham, ME | 9 |
| Krupin, T | 1 |
| Weiss, A | 1 |
| Becker, B | 1 |
| Holmberg, N | 1 |
| Fritz, C | 1 |
| Leopold, IH | 1 |
| Murray, DL | 1 |
| Waitzman, MB | 3 |
| Woods, WD | 1 |
| Cheek, WV | 1 |
| Bigger, JF | 1 |
| Bowman, K | 1 |
| Palewicz, K | 1 |
| Macri, FJ | 2 |
| Cevario, SJ | 2 |
| Krieglstein, GK | 1 |
| Neufeld, AH | 1 |
| Jampol, LM | 1 |
| Radius, R | 1 |
| Simjee, A | 1 |
| Josephs, S | 1 |
| Diggs, E | 1 |
| Carmel, DD | 1 |
| Diggs, EM | 1 |
| Bhattacherjee, P | 1 |
| Burberi, P | 1 |
| Piccinelli, D | 1 |
| Silvestrini, B | 1 |
| McDonald, TO | 1 |
| Hodges, JW | 1 |
| Borgmann, AR | 1 |
| Leaders, FE | 1 |
25 other studies available for phenoxybenzamine and Intraocular Pressure
| Article | Year |
|---|---|
THE TRABECULAR EFFECT OF NORADRENALIN IN THE RABBIT EYE.
Topics: Animals; Aqueous Humor; Blood Vessels; Ciliary Body; Denervation; Eye Proteins; Ganglia; Glaucoma; I | 1964 |
Does prostacyclin mediate alpha-adrenergic induced hypotension?
Topics: Animals; Aqueous Humor; Epinephrine; Epoprostenol; Indomethacin; Intraocular Pressure; Iris; Isoprot | 1982 |
Drug effects on aqueous humor formation and pseudofacility in normal rabbit eyes.
Topics: Animals; Aqueous Humor; Atropine; Bradykinin; Dexamethasone; Dopamine; Intraocular Pressure; Melanoc | 1981 |
Interaction of adrenergic antagonists with prostaglandin E2 and tetrahydrocannabinol in the eye.
Topics: 1-Propanol; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cann | 1976 |
The intraocular pressure response of conscious rabbits to clonidine.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationshi | 1976 |
Increased intraocular pressure following topical azide or nitroprusside.
Topics: Administration, Topical; Animals; Aqueous Humor; Ascorbic Acid; Azides; Cyclic GMP; Dose-Response Re | 1977 |
Ocular hypotensive action of labetalol.
Topics: Animals; Ethanolamines; Female; Intraocular Pressure; Isoproterenol; Labetalol; Norepinephrine; p-Hy | 1979 |
Effects of prostaglandins and norepinephrine on ocular pressure and pupil size in rabbits following bilateral cervical ganglionectomy.
Topics: Animals; Ganglia, Autonomic; Indomethacin; Intraocular Pressure; Male; Mydriatics; Norepinephrine; P | 1979 |
Cannabinoid action on the eye as mediated through the central nervous system and local adrenergic activity.
Topics: Animals; Brain; Cannabinoids; Dronabinol; Eye; Ganglia, Autonomic; Intraocular Pressure; Phenoxybenz | 1977 |
The pupillary, the intraocular pressure and the vasomotor responses to noradrenaline in rabbits.
Topics: Animals; Aqueous Humor; Female; Intraocular Pressure; Male; Norepinephrine; Phenoxybenzamine; Pupil; | 1977 |
Ciliary ganglion stimulation. II. Neurogenic, intraocular pathway for excitatory effects on aqueous humor production and outflow.
Topics: Acetylcholine; Animals; Aqueous Humor; Atropine; Bretylium Compounds; Cats; Ciliary Body; Electric S | 1975 |
The biphasic intraocular pressure response of rabbits to epinephrine.
Topics: Administration, Topical; Animals; Epinephrine; Intraocular Pressure; Phenoxybenzamine; Propranolol; | 1976 |
Cyclic-AMP in the aqueous humor: the effects of adrenergic agents.
Topics: Aminophylline; Animals; Aqueous Humor; Caffeine; Ciliary Body; Cornea; Cyclic AMP; Epinephrine; Intr | 1972 |
Cyclic-AMP and the ocular responses to norepinephrine.
Topics: Adenylyl Cyclases; Administration, Topical; Animals; Aqueous Humor; Biometry; Cyclic AMP; Enzyme Ind | 1973 |
Effects of prostaglandin and beta-adrenergic drugs on ocular pressure and pupil size.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Drug Antagonism; Intraocular Pressur | 1969 |
The alpha and beta adrenergic responses to epinephrine in the rabbit eye.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Epinephrine; Eye | 1973 |
Beta-adrenergic responses in the eyes of rabbits, primates, and man.
Topics: Administration, Topical; Adult; Albuterol; Animals; Aqueous Humor; Ascorbic Acid; Dilatation; Eye; H | 1974 |
The induction of aqueous humor formation by the use of Ach+eserine.
Topics: Acetylcholine; Animals; Aqueous Humor; Atropine; Cats; Ganglia, Autonomic; Guanethidine; Hexamethoni | 1973 |
The action of protriptyline on adrenergic mechanisms in rabbit, primate and human eyes.
Topics: Animals; Antidepressive Agents; Aqueous Humor; Dilatation; Electric Stimulation; Eye; Glaucoma; Hapl | 1968 |
Pupil size and ocular pressure after sympathectomy and prostaglandin-catecholamine treatment.
Topics: Animals; Biometry; Eye; Ganglia, Autonomic; Intraocular Pressure; Male; Neck; Norepinephrine; Phenox | 1970 |
Quantitative studies of the ocular response to norepinephrine.
Topics: Animals; Cornea; Epithelium; Injections; Intraocular Pressure; Iris; Norepinephrine; Phenoxybenzamin | 1972 |
Effects of catecholamines on the ocular tension of normal and sympathetically denervated rabbit eyes.
Topics: Animals; Anterior Chamber; Autoradiography; Catecholamines; Cornea; Denervation; Epinephrine; Eye; I | 1971 |
Effects of systemically administered drugs on intraocular pressure in rabbits.
Topics: Acetazolamide; Amphetamine; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressu | 1970 |
The water-loading test in rabbits. A method to detect potential ocular hypotensive drugs.
Topics: Acetazolamide; Animals; Atropine; Carbachol; Dichlorphenamide; Epinephrine; Glaucoma; Hexamethonium | 1969 |
The response of the pupil and intraocular pressure of conscious rabbits to adrenergic drugs following unilateral superior cervical ganglionectomy.
Topics: Animals; Intraocular Pressure; Isoproterenol; Norepinephrine; Phenoxybenzamine; Pupil; Rabbits; Symp | 1965 |