Page last updated: 2024-11-02

phenoxybenzamine and Hypothermia

phenoxybenzamine has been researched along with Hypothermia in 15 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

ExcerptRelevanceReference
"To investigate the mechanism of the antagonistic effect of Na-((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L-prolin amide monohydrate (CAS 131404-34-7, JTP-2942) on reserpine-induced hypothermia, the role of the autonomic nervous system, adrenal gland, and thyroid gland regarding the effects of JTP-2942 has been studied in mice."7.69Mechanism of the hyperthermic effect of the novel thyrotropin-releasing hormone analogue Na-((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L- prolinamide monohydrate in mice with reserpine-induced hypothermia. ( Iwata, K; Matsushita, M; Ohta, A; Yonemori, F, 1995)
"To investigate the mechanism of the antagonistic effect of Na-((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L-prolin amide monohydrate (CAS 131404-34-7, JTP-2942) on reserpine-induced hypothermia, the role of the autonomic nervous system, adrenal gland, and thyroid gland regarding the effects of JTP-2942 has been studied in mice."3.69Mechanism of the hyperthermic effect of the novel thyrotropin-releasing hormone analogue Na-((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L- prolinamide monohydrate in mice with reserpine-induced hypothermia. ( Iwata, K; Matsushita, M; Ohta, A; Yonemori, F, 1995)
"The authors report two cases of hypothermia due to a treatment associating Bethanechol and Adreno-Blockers."3.67Effects of bethanechol and adreno-blockers on thermoregulation in spinal cord injury. ( Berard, EJ; Boucand, MH; Depassio, J; Fyon, JP, 1989)
"The effects of morphine and pethidine upon body temperature and upon the reversal of reserpine hypothermia in the mouse were investigated."3.65A comparison of the effects of morphine and pethidine upon body temperature and the reversal of reserpine's effects upon body temperature in the mouse. ( Menon, AM; Pleuvry, BJ, 1976)
" Intraventricular injection of phenylephrine produced a dose-dependent hypothermia, whereas no dose-response relationship was obtained by isoproterenol."1.25[Role of brain biogenic amines in the central thermoregulatory mechanism of the rat (author's transl)]. ( Fukushima, N, 1975)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199014 (93.33)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
VARMA, DR1
GILLIS, RA1
MELVILLE, KI1
Matsushita, M1
Yonemori, F1
Ohta, A1
Iwata, K1
Fukushima, N2
Itoh, S1
Menon, AM1
Pleuvry, BJ1
Brick, J1
Pohorecky, LA1
Drawbaugh, RB1
Lal, H1
Berard, EJ1
Boucand, MH1
Depassio, J1
Fyon, JP1
Kar, K1
Sur, RN1
Pradhan, SN1
Fisher, DA1
Odell, WD1
Yehuda, S1
Wurtman, RJ1
Mozes, MF1
Toledo-Pereyra, LH1
Campos, RA1
Moberg, AW1
Najarian, JS1
Cooper, F1
Leonard, BE1
Schnieden, H1
Davis, RA1
Steyn, J1
Mobley, TL1
Suwanagul, A1

Other Studies

15 other studies available for phenoxybenzamine and Hypothermia

ArticleYear
On the relationship of catecholamines and thyroid activity to ventricular fibrillation during hypothermia in dogs.
    Canadian journal of biochemistry and physiology, 1963, Volume: 41

    Topics: Animals; Antithyroid Agents; Catecholamines; Dogs; Epinephrine; Hypothermia; Hypothermia, Induced; I

1963
Mechanism of the hyperthermic effect of the novel thyrotropin-releasing hormone analogue Na-((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L- prolinamide monohydrate in mice with reserpine-induced hypothermia.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:6

    Topics: Adrenal Medulla; Animals; Body Temperature; Hexamethonium; Hypothermia; Hypothyroidism; Male; Mice;

1995
Role of adrenergic receptors in the central thermoregulatory mechanism of the rat.
    The Japanese journal of physiology, 1975, Volume: 25, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Body Temperature Regulation; Hypothermia; Male; Norepinephrine

1975
A comparison of the effects of morphine and pethidine upon body temperature and the reversal of reserpine's effects upon body temperature in the mouse.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:11

    Topics: Adrenalectomy; Animals; Body Temperature; Dose-Response Relationship, Drug; Female; Hypothermia; Mal

1976
Ethanol withdrawal: altered ambient temperature selection in rats.
    Alcoholism, clinical and experimental research, 1977, Volume: 1, Issue:3

    Topics: Amphetamine; Animals; Behavior, Animal; Body Temperature; Choice Behavior; Decision Making; Ethanol;

1977
Effect of pharmacological interference with various neuropathways on blockade of morphine-withdrawal hypothermia by morphine and by conditional stimulus.
    Neuropharmacology, 1976, Volume: 15, Issue:6

    Topics: Animals; Benztropine; Conditioning, Classical; Cyproheptadine; Haloperidol; Humans; Hypothermia; Mal

1976
[Role of brain biogenic amines in the central thermoregulatory mechanism of the rat (author's transl)].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1975, Volume: 50, Issue:4

    Topics: Adaptation, Physiological; Animals; Biogenic Amines; Blood Glucose; Body Temperature Regulation; Cer

1975
Effects of bethanechol and adreno-blockers on thermoregulation in spinal cord injury.
    Paraplegia, 1989, Volume: 27, Issue:1

    Topics: Adult; Bethanechol; Bethanechol Compounds; Body Temperature Regulation; Humans; Hypothermia; Male; P

1989
Depressor response to noradrenaline in hypothermic cats.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Acetazolamide; Acetylcholine; Animals; Atropine; Bicarbonates; Blood Pressure; Calcium; Cats; Depres

1969
Effect of cold on TSH secretion in man.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 33, Issue:5

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Cold Temperature; Humans; Hypothalamus; Hypothermia;

1971
Release of brain dopamine as the probable mechanism for the hypothermic effect of D-amphetamine.
    Nature, 1972, Dec-22, Volume: 240, Issue:5382

    Topics: Animals; Apomorphine; Brain Chemistry; Clonidine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamin

1972
Prevention of irreversible ischemic damage in renal preservation by pharmacological manipulation.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1974, Issue:4

    Topics: Allopurinol; Animals; Chlorpromazine; Dogs; Hypothermia; Ischemia; Kidney Transplantation; Methylpre

1974
The role of catecholamines in the reversal of reserpine-induced hypothermia in mice by desipramine and chlorpromazine.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Animals; Body Temperature; Catecholamines; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Dose

1972
Induction of fatal hypothermia in house-mice.
    The Annals of applied biology, 1968, Volume: 61, Issue:2

    Topics: Animals; Body Temperature; Chlorpromazine; Hydralazine; Hypothermia; Mecamylamine; Methyldopa; Mice;

1968
Factors influencing extracorporeal hypothermic perfusion of the isolated canine kidney.
    British journal of urology, 1966, Volume: 38, Issue:6

    Topics: Animals; Blood Flow Velocity; Carbon Dioxide; Dextrans; Dogs; Hypothermia; Kidney; Mannitol; Perfusi

1966