Page last updated: 2024-11-02

phenoxybenzamine and Hypercapnia

phenoxybenzamine has been researched along with Hypercapnia in 15 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.

Research Excerpts

ExcerptRelevanceReference
" In contrast to the sustained stimulation of ventilation produced by hypoxia in normal subjects, hypoxia either did not change, or decreased, the [unk]V(E)-P(ACo2) slope of dysautonomic patients and phenoxybenzamine-treated goats; CO(2)-free hypoxia produced a fleeting hyperventilation, which was followed by apnea when hypoxia was abruptly relieved."3.65The effects of abnormal sympathetic nervous function upon the ventilatory response to hypoxia. ( Cherniack, NS; Edelman, NH; Fishman, AP; Lahiri, S; Richards, E, 1970)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199014 (93.33)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bersentes, TJ1
Simmons, DH2
Anderson, RJ1
Henrich, WL1
Gross, PA1
Dillingham, MA1
Dhabuwala, CB1
Bird, M1
Salaman, JR1
Saeki, Y1
Sato, A1
Sato, Y1
Trzebski, A1
Saphir, R1
Rapaport, E1
Kontos, HA3
Richardson, DW3
Patterson, JL3
Raper, AJ1
Pelletier, CL1
Shepherd, JT1
Tashkin, DP1
Goldstein, PJ1
Edelman, NH1
Cherniack, NS1
Lahiri, S1
Richards, E1
Fishman, AP1
Gonzalez, NC1
Hojo, T1
Brown, EB1
Dos, SJ1
Landé, AJ1
Lillehei, CW1
Maklári, E1
Kellner, M1
Kovách, AG1
Gottsegen, G1
Barer, GR1

Trials

1 trial available for phenoxybenzamine and Hypercapnia

ArticleYear
Contribution of hypercapnia and hypoxia to the vascular response to ischaemia.
    Clinical science, 1970, Volume: 39, Issue:2

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; B

1970

Other Studies

14 other studies available for phenoxybenzamine and Hypercapnia

ArticleYear
Effects of acute acidosis on renal hemodynamics.
    The American journal of physiology, 1967, Volume: 212, Issue:3

    Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Animals; Blood Circulation; Blood Flow Veloc

1967
Role of renal nerves, angiotensin II, and prostaglandins in the antinatriuretic response to acute hypercapnic acidosis in the dog.
    Circulation research, 1982, Volume: 50, Issue:2

    Topics: Acidosis; Acute Disease; Angiotensin II; Animals; Blood Gas Analysis; Blood Pressure; Cardiac Output

1982
Relative importance of warm ischaemia, hypotension, and hypercarbia in producing renal vasospasm.
    Transplantation, 1979, Volume: 27, Issue:4

    Topics: Animals; Blood Circulation; Blood Pressure; Female; Hot Temperature; Hypercapnia; Hypotension; Ische

1979
Effects of stimulation of cervical sympathetic trunks with various frequencies on the local cortical cerebral blood flow measured by laser Doppler flowmetry in the rat.
    The Japanese journal of physiology, 1990, Volume: 40, Issue:1

    Topics: Animals; Blood Flow Velocity; Cerebrovascular Circulation; Electric Stimulation; Hypercapnia; Lasers

1990
Cardiovascular responses of the cat to mesenteric intra-arterial administration of nicotine, cyanide and venous blood.
    Circulation research, 1969, Volume: 25, Issue:6

    Topics: Animals; Atropine; Autonomic Nervous System; Blood Flow Velocity; Blood Pressure; Cardiovascular Sys

1969
Effects of hypercapnia on human forearm blood vessels.
    The American journal of physiology, 1967, Volume: 212, Issue:5

    Topics: Blood Flow Velocity; Blood Pressure; Blood Vessels; Carbon Dioxide; Ethanolamines; Forearm; Humans;

1967
Venous responses to stimulation of carotid chemoreceptors by hypoxia and hypercapnia.
    The American journal of physiology, 1972, Volume: 223, Issue:1

    Topics: Animals; Atropine; Blood Pressure; Carbon Dioxide; Carotid Sinus; Chemoreceptor Cells; Chloralose; D

1972
Effect of acute respiratory acidosis on mesenteric circulation of dogs.
    The American journal of physiology, 1969, Volume: 217, Issue:6

    Topics: Acidosis, Respiratory; Animals; Bicarbonates; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; C

1969
The effects of abnormal sympathetic nervous function upon the ventilatory response to hypoxia.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:6

    Topics: Animals; Apnea; Blood Pressure; Central Nervous System; Chemoreceptor Cells; Dysautonomia, Familial;

1970
Myocardial potassium uptake with constant arterial potassium concentration.
    Journal of applied physiology, 1968, Volume: 24, Issue:4

    Topics: Animals; Blood Flow Velocity; Coronary Vessels; Dogs; Hypercapnia; Hyperkalemia; Infusions, Parenter

1968
Hypercapnic cerebrospinal fluid hypertension: a pharmacological study.
    Surgery, 1968, Volume: 63, Issue:5

    Topics: Animals; Arteries; Blood Pressure Determination; Carbon Dioxide; Chlorpromazine; Dexamethasone; Dext

1968
Roles of hypercapnia and acidosis in the vasodilator response to hypercapnic acidosis.
    The American journal of physiology, 1968, Volume: 215, Issue:6

    Topics: Acidosis; Bicarbonates; Blood Pressure; Blood Vessels; Carbon Dioxide; Forearm; Heart Rate; Humans;

1968
Studies in experimental pulmonary oedema. II. Effect of dibenzyline on pulmonary oedema induced by hyperoxygenation.
    Acta medica Academiae Scientiarum Hungaricae, 1966, Volume: 23, Issue:1

    Topics: Animals; Carbon Dioxide; Hyperbaric Oxygenation; Hypercapnia; Oxygen Consumption; Phenoxybenzamine;

1966
The effect of catecholamine blocking and depleting agents on the changes in the pulmonary circulation caused by hypoxia and hypercapnia.
    The Journal of physiology, 1966, Volume: 186, Issue:2

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cats; Hypercapnia; Hypoxia; Lung; Phenoxybenzamine; Pulmona

1966