Page last updated: 2024-11-02

phenoxybenzamine and Hemorrhagic Shock

phenoxybenzamine has been researched along with Hemorrhagic Shock in 122 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Research Excerpts

ExcerptRelevanceReference
"Hemorrhagic shock is associated with lactic acidosis and increased plasma catecholamines."7.70Adrenergic antagonists reduce lactic acidosis in response to hemorrhagic shock. ( Frame, SB; Friend, LA; James, JH; Luchette, FA; McCarter, F; Robinson, BR, 1999)
"When the opiate antagonist naloxone is administered to anesthetized dogs subjected to hemorrhagic shock, there is a transient decrease in heart rate and sustained increases in mean arterial pressure, maximum left ventricular dp/dt, and cardiac output."7.67Role of the autonomic nervous system in mediating the response to naloxone in canine hemorrhagic shock. ( Gurll, NJ; Lechner, RB; Reynolds, DG, 1985)
" This study evaluates the effects of hemorrhagic shock, with and without combined alpha- and beta-adrenergic receptor blockade, on lactate production, glycogenolysis, Na(+)-K(+) pump activity, and high-energy phosphates in rat skeletal muscle."3.71Adrenergic blockade reduces skeletal muscle glycolysis and Na(+), K(+)-ATPase activity during hemorrhage. ( Evans, JM; Fischer, JE; Friend, LA; George, MA; James, JH; King, JK; Luchette, FA; McCarter, FD; Wang, L, 2001)
"Hemorrhagic shock is associated with lactic acidosis and increased plasma catecholamines."3.70Adrenergic antagonists reduce lactic acidosis in response to hemorrhagic shock. ( Frame, SB; Friend, LA; James, JH; Luchette, FA; McCarter, F; Robinson, BR, 1999)
"When the opiate antagonist naloxone is administered to anesthetized dogs subjected to hemorrhagic shock, there is a transient decrease in heart rate and sustained increases in mean arterial pressure, maximum left ventricular dp/dt, and cardiac output."3.67Role of the autonomic nervous system in mediating the response to naloxone in canine hemorrhagic shock. ( Gurll, NJ; Lechner, RB; Reynolds, DG, 1985)
"The involvement of adrenergic mechanisms in the ability of massive doses of methylprednisolone to potentiate the vasodilatory effects of phenoxybenzamine during controlled hemorrhagic shock was investigated."3.66Effects of adrenergic neuron and ganglion blockers on hemodynamics and plasma catecholamine levels after corticosteroids during hemorrhagic shock in the dog. ( Häggendal, E; Häggendal, J; Haglund, U; Hellman, A; Lundberg, D, 1980)
"The adrenergic aspects of the mechanism(s) of the vasodilating action of phenoxybenzamine and massive doses of hydrocortisone were studied in anesthetized dogs subjected to controlled hemorrhagic shock."3.66Effects of hydrocortisone, phenoxybenzamine and propranolol on the blood plasma levels of adrenaline and noradrenaline during hemorrhagic hypotension in the dog. ( Häggendal, E; Häggendal, J; Hellman, A; Lundberg, D, 1980)
"Like cardiogenic shock, hemorrhagic shock generates selective mesenteric ischemia by producing a disproportionate mesenteric vasospasm that is mediated primarily by the renin-angiotensin axis."1.31Mesenteric vasoconstriction in response to hemorrhagic shock. ( Bulkley, GB; Ferris, R; Fuh, KC; Reilly, PM; Toung, T, 2000)

Research

Studies (122)

TimeframeStudies, this research(%)All Research%
pre-1990118 (96.72)18.7374
1990's2 (1.64)18.2507
2000's2 (1.64)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
PORCIUNCULA, CI1
CROWELL, JW3
GOURZIS, JT1
ROQUE, N1
NICKERSON, M3
SMITH, EE2
LILLEHEI, RC4
LONGERBEAM, JK2
BLOCH, JH2
MANAX, WG3
POLLOCK, L1
KJARTANSSON, KB1
DELIN, NA1
SCHENK, WG1
WILSON, RF1
JABLONSKI, DV1
THAL, AP1
FLINN, RB1
UNAL, M1
WEBB, WR2
ASLAMI, A1
SHARMA, GP1
EISEMAN, B1
VICK, JA1
CIUCHTA, HP1
MERICKEL, JH1
LINDSETH, EO1
FITTS, CT1
SAWYER, RB1
ZARRO, VJ1
DIPALMA, JR1
MURPHY, GP1
GAGNON, JA1
EWALD, RA1
BERGER, RL1
NOVOGRADAC, WE1
BYRNE, JJ1
Dow, RW1
Fry, WJ1
Grega, GJ2
Kinnard, WJ2
Buckley, JP1
Palmerio, C1
Nahor, A1
Minton, R1
Fine, J1
Halmagyi, DF6
Gillett, DJ3
Irving, MH5
Rush, BF2
Cowsert, MK1
Carrier, O1
Varga, D4
Dietzman, RH2
Cook, JR1
Sherrod, TR1
Cooley, JC1
Ankeney, JL1
Coffin, LH1
Littell, AS1
Stekiel, WJ1
Logic, JR1
Erdelyi, A1
Rozek, LF1
Cooper, D1
Skillman, JJ1
Ciampa, GR1
Edwards, EA1
Ikrényi, C1
Koltay, E2
Kovách, AG9
Gunther, B1
Vivaldi, E1
Haglund, U2
Hellman, A5
Häggendal, E6
Häggendal, J2
Lundberg, D7
Hirsch, LJ1
Rone, AS1
Bond, RF1
Johnson, G1
Jones, CE1
Farrell, TA1
Ator, R1
Haljamäe, H1
Jennische, E1
Ploucha, JM1
Scott, JB1
Ringer, RK1
Luchette, FA2
Robinson, BR1
Friend, LA2
McCarter, F1
Frame, SB1
James, JH2
Toung, T1
Reilly, PM1
Fuh, KC1
Ferris, R1
Bulkley, GB1
McCarter, FD1
Wang, L1
King, JK1
Evans, JM1
George, MA1
Fischer, JE1
Lindfors, M3
Becker, H1
Birinyi, F1
Hackel, DB1
Mikat, E1
Feigen, LP1
Coleman, B1
Glaviano, VV1
Yamada, S1
Fukuda, Y1
Fukuhara, T1
Matsuzaki, K1
Yoshinare, T1
Kashyap, ML1
Tay, JS1
Sothy, SP1
Morrison, JA1
Carlson, EL1
Selinger, SL1
Utley, J1
Hoffman, JI1
Zheng, D1
Chen, HS1
Hu, DY1
Lechner, RB1
Gurll, NJ1
Reynolds, DG1
Krnic, J1
Hamamdzic, M1
Duzic, E1
Magazinovic, V1
Elkin, M1
Meng, CH1
Mendez, L1
Corssen, G2
Reves, JG1
Carter, JR1
Rubányi, G1
Huszár, L1
Sándor, P4
Clauss, RH1
Ray, JF1
Ranganathan, N1
Phillips, JH1
Stallworth, JM1
Ramirez, A1
Barrington, BA1
Bradham, RR1
Grandchamp, A1
Ayer, G1
Truniger, B1
Jakschik, BA1
Marshall, GR1
Kourik, JL1
Needleman, P1
Chodoff, P1
al-Katib, HA1
Baba, WI1
Zierott, G2
Riedwyl, H1
Lundsgaard-Hansen, P2
Nelson, NC1
Nelson, JL1
Weldon, WE1
Vela, AR1
Rosell, S2
Kovách, E1
Tomka, N1
Hollenberg, NK2
Waters, JR1
Toews, MR1
Davies, RO1
Kennedy, M3
Goodman, AH2
Teres, D1
Strack, PR1
Regan, TJ1
Hardaway, RM2
Dreikorn, K1
Beduhn, D1
Yu, W1
Shim, SS1
Hawk, HE1
Das, P1
Kutty, G1
Alguire, PA1
Bowman, HM1
Hook, JB1
Kurahashi, H1
Motsay, GJ1
Matsumoto, T2
Heisterkamp, CA1
Heiffer, MH1
Hawkey, C1
Nagy, Z1
Mészáros, A1
Vaslaki, L1
Hanaoka, H1
McClain, JE1
Margetis, PM1
van Gool, J1
Reerink, E1
Hashimoto, Y1
Lydtin, H1
Bennett, HD1
Messmer, K1
Cattaneo, AD1
Sharma, PL1
Neely, WA1
Windham, TL1
Makin, GS2
Walder, DN1
Greene, JA1
Lapco, L1
Weller, JM1
Bell, G1
Lister, GD1
Shoemaker, WC1
Brown, RS1
Torsti, P1
Mills, LC1
Moyer, JH1
Novelli, GP1
Zampolini, M1
Celiberti, A1
Cortesini, C1
Pagni, E1
Ahnefeld, FW1
Halmágyi, M1
Mancuso, M1
Altissimi, C1
Drago, G1
Sarcinelli, L1
Hardcastle, JD1
Ritchie, HD1
Maklári, E1
Schumer, W2
Sugg, WL1
Ecker, RR1
Konuralp, HZ1
Or, F2
Altug, K2
Koçak, N1
Ozkanli, O1
Yoshida, T1
Yasuda, K1
Kumagaya, T1
Taketani, Y1
Hata, T1
Simon, L1
Kunos, G1
Marton, I1
Kun, E1
Pappova, E1
Muhm, HY2
Shumacker, HB2
Rosenberg, JC1
Spencer, FC1
Baue, AE1
Johnson, DG1
Parkins, WM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Use of Nitroglycerine to Improve Signs of Poor Peripheral Perfusion in Patients With Traumatic Hemorrhagic Shock[NCT03235921]Phase 2100 participants (Anticipated)Interventional2016-03-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for phenoxybenzamine and Hemorrhagic Shock

ArticleYear
Neuroleptanesthesia, dissociative anesthesia, and hemorrhage.
    International anesthesiology clinics, 1974,Spring, Volume: 12, Issue:1

    Topics: Adrenergic alpha-Antagonists; Anesthetics; Anesthetics, Dissociative; Animals; Anti-Arrhythmia Agent

1974
Pharmacologic assistance to the failing circulation.
    Surgery, gynecology & obstetrics, 1968, Volume: 126, Issue:3

    Topics: Adenosine Triphosphatases; Aminophylline; Angiotensin II; Blood Gas Analysis; Blood Pressure; Cardia

1968

Other Studies

120 other studies available for phenoxybenzamine and Hemorrhagic Shock

ArticleYear
QUANTITATIVE STUDY OF INTESTINAL FLUID LOSS IN IRREVERSIBLE HEMORRHAGIC SHOCK.
    The American journal of physiology, 1963, Volume: 205

    Topics: Animals; Atropine; Body Fluids; Dogs; Hypotension; Intestine, Small; Intestines; Pharmacology; Pheno

1963
CHEMICAL STRUCTURE AND ANTISHOCK ACTIVITY AMONG COMPOUNDS RELATED TO PHENOXYBENZAMINE (DIBENZYLINE).
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 141

    Topics: Animals; Blood Pressure; Dogs; Hematocrit; Pharmacology; Phenoxybenzamine; Rats; Research; Shock, He

1963
OXYGEN DEFICIT AND IRREVERSIBLE HEMORRHAGIC SHOCK.
    The American journal of physiology, 1964, Volume: 206

    Topics: Animals; Digitalis; Digitalis Glycosides; Dogs; Epinephrine; Hypotension; Hypoxia; Metabolism; Norep

1964
THE NATURE OF EXPERIMENTAL IRREVERSIBLE SHOCK WITH ITS CLINICAL APPLICATION.
    International anesthesiology clinics, 1964, Volume: 2

    Topics: Animals; Blood Circulation; Blood Flow Velocity; Blood Transfusion; Blood Volume; Catecholamines; De

1964
REGIONAL BLOOD FLOW ALTERATIONS. STUDIES OF CHANGES IN THIS COURSE PRODUCED BY A VASOCONSTRICTOR AND AN ADRENERGIC BLOCKING AGENT DURING READJUSTMENT TO HEMORRHAGIC SHOCK.
    Archives of surgery (Chicago, Ill. : 1960), 1964, Volume: 89

    Topics: Adrenergic Antagonists; Animals; Blood Circulation; Blood Flow Velocity; Blood Pressure; Dogs; Norep

1964
THE USAGE OF DIBENZYLINE IN CLINICAL SHOCK.
    Surgery, 1964, Volume: 56

    Topics: Aortic Aneurysm; Biomedical Research; Blood Pressure Determination; Duodenal Ulcer; Geriatrics; Hear

1964
THE PREVENTION OF ACTIVE TUBULAR NECROSIS IN HEMORRHAGIC SHOCK.
    Delaware medical journal, 1964, Volume: 36

    Topics: Dextrans; Kidney Function Tests; Kidney Tubules; Lidocaine; Mannitol; Necrosis; Phenoxybenzamine; Pr

1964
METABOLIC RESPONSES TO VARIOUS VASOACTIVE AND CARDIOTONIC AGENTS IN HYPOVOLEMIA.
    Surgical forum, 1964, Volume: 15

    Topics: Angiotensins; Animals; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Determinati

1964
PROTECTIVE EFFECT OF ADENOSINE TRIPHOSPHATE IN EXPERIMENTAL HEMORRHAGIC SHOCK.
    Surgical forum, 1964, Volume: 15

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Heart; Metabolism; Pharmacology; Phenoxybenzamine; Rats

1964
THE NATURE OF IRREVERSIBLE SHOCK: EXPERIMENTAL AND CLINICAL OBSERVATIONS.
    Annals of surgery, 1964, Volume: 160

    Topics: Blood Flow Velocity; Blood Pressure Determination; Blood Transfusion; Blood Volume Determination; Co

1964
EFFECT OF HEMORRHAGIC HYPOTENSION ON OXYGEN CONSUMPTION OF DOGS.
    The American journal of physiology, 1964, Volume: 207

    Topics: Blood Flow Velocity; Dogs; Epinephrine; Hematocrit; Homeostasis; Hypotension; Metabolism; Oximetry;

1964
VASODILATOR THERAPY IN ACUTE HEMORRHAGIC SHOCK.
    Circulation research, 1965, Volume: 16

    Topics: Blood Circulation; Blood Gas Analysis; Blood Volume; Carbon Dioxide; Dogs; Hemodynamics; Hypotension

1965
THE USE OF DRUGS IN THE TREATMENT OF IRREVERSIBLE VASOCONSTRICTOR SHOCK.
    The Journal of trauma, 1965, Volume: 5

    Topics: Dextrans; Dogs; Heparin; Norepinephrine; Pharmacology; Phenoxybenzamine; Research; Shock; Shock, Hem

1965
THE SYMPATHOMIMETIC EFFECTS OF 2-PYRIDINE ALDOXIME METHYLCHLORIDE (2-PAM CL).
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 147

    Topics: Animals; Atropine; Blood; Blood Pressure; Catecholamines; Cats; Diphosphates; Dogs; Ganglia; Ganglio

1965
RENAL AND SYSTEMIC HEMODYNAMIC EFFECTS OF DIBENZYLINE IN NORMOTENSION AND HEMORRHAGIC HYPOTENSION.
    Surgery, 1965, Volume: 57

    Topics: Animals; Blood Circulation; Blood Pressure; Blood Volume; Dogs; Hemodynamics; Hemorrhage; Hypotensio

1965
SURGICAL AND CHEMICAL DENERVATION OF ABDOMINAL VISCERA IN IRREVERSIBLE HEMORRHAGIC SHOCK.
    Annals of surgery, 1965, Volume: 162

    Topics: Abdomen; Animals; Autonomic Nerve Block; Blood Circulation; Dogs; Hemodynamics; Mesentery; Pharmacol

1965
Hemorrhagic shock. Changes in renal blood flow and vascular resistance.
    Archives of surgery (Chicago, Ill. : 1960), 1967, Volume: 94, Issue:2

    Topics: Acute Kidney Injury; Animals; Blood Flow Velocity; Blood Pressure; Blood Transfusion; Chlorpromazine

1967
Effects of nylidrin, isoproterenol and phenoxybenzamine on dogs subjected to hemorrhagic shock.
    Circulation research, 1967, Volume: 20, Issue:2

    Topics: Animals; Dogs; Isoproterenol; Phenoxybenzamine; Shock, Hemorrhagic; Vasodilator Agents

1967
Limitations of antiadrenergic therapy for refractory traumatic shock.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 124, Issue:2

    Topics: Animals; Autonomic Nerve Block; Celiac Plexus; Dogs; Hemodynamics; Phenoxybenzamine; Rabbits; Shock,

1967
Partial and "complete" adrenergic blockade in posthemorrhagic shock.
    Journal of applied physiology, 1967, Volume: 22, Issue:3

    Topics: Acidosis; Animals; Bicarbonates; Blood Pressure; Blood Volume; Carbon Dioxide; Cardiac Output; Dogs;

1967
Treatment of experimental shock: comparison of the effects of norepinephrine, dibenzyline, dextran, whole blood, and balanced saline solutions.
    Surgery, 1967, Volume: 61, Issue:6

    Topics: Animals; Blood Pressure; Blood Transfusion; Body Temperature; Cardiac Output; Dextrans; Dogs; Hemato

1967
The effect of some autonomic drugs on the uric acidemia of hemorrhagic shock.
    Canadian journal of physiology and pharmacology, 1967, Volume: 45, Issue:1

    Topics: Animals; Blood Pressure; Dogs; Female; Hypoxia; Isoproterenol; Male; Norepinephrine; Phenoxybenzamin

1967
Effect of adrenergic blockade on consequences of sustained epinephrine infusion.
    Journal of applied physiology, 1967, Volume: 23, Issue:2

    Topics: Animals; Blood; Blood Glucose; Carbon Dioxide; Dexamethasone; Epinephrine; Hematocrit; Hydrocortison

1967
Shock: mechanisms and therapy.
    Canadian Anaesthetists' Society journal, 1967, Volume: 14, Issue:4

    Topics: Animals; Chlorpromazine; Digitalis Glycosides; Dogs; Endotoxins; Epinephrine; Equipment and Supplies

1967
Myocardial contractile force in hemorrhagic shock. Treatment with phenoxybenzamine hydrochloride, metaproterenol sulfate, or these agents combined.
    Archives of surgery (Chicago, Ill. : 1960), 1967, Volume: 95, Issue:3

    Topics: Animals; Blood Pressure; Bronchodilator Agents; Dogs; Heart; Hydrogen-Ion Concentration; Metaprotere

1967
Experimental evidence that vasoconstriction in hemorrhagic shock does not result in anaerobic metabolism.
    Annals of surgery, 1967, Volume: 166, Issue:3

    Topics: Animals; Blood Volume; Carbon Dioxide; Computers; Dogs; Epinephrine; Glucose; Hydrogen-Ion Concentra

1967
Effect of phenoxybenzamine on plasma volumes during hemorrhagic shock.
    The American journal of physiology, 1967, Volume: 213, Issue:5

    Topics: Animals; Blood Volume; Blood Volume Determination; Dogs; Hematocrit; Phenoxybenzamine; Shock, Hemorr

1967
External pulse recording in experimental hemorrhage and drug infusion in man.
    Surgery, gynecology & obstetrics, 1967, Volume: 125, Issue:6

    Topics: Adult; Blood Pressure; Blood Volume; Cardiac Output; Cardiovascular System; Hemodynamics; Hemorrhage

1967
Effect of alpha receptor blocking drugs and vasodilators on metabolic changes in hemorrhagic shock.
    Zeitschrift fur medizinische Laboratoriumsdiagnostik, 1982, Apr-02, Volume: 23, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aminophylline; Animals; Energy Metabolism; Male; Phenoxybenzamine; Phe

1982
Effects of ganglionic and alpha adrenergic blocking agents on the hemorrhagic shock in dogs.
    Archivos de biologia y medicina experimentales, 1980, Volume: 13, Issue:4

    Topics: Animals; Blood Pressure; Dibenzylchlorethamine; Dogs; Hexamethonium; Hexamethonium Compounds; Phenox

1980
Effects of adrenergic neuron and ganglion blockers on hemodynamics and plasma catecholamine levels after corticosteroids during hemorrhagic shock in the dog.
    Acta anaesthesiologica Scandinavica, 1980, Volume: 24, Issue:6

    Topics: Adrenal Medulla; Animals; Bretylium Compounds; Dogs; Epinephrine; Female; Hemodynamics; Hexamethoniu

1980
Hepatic arterial and portal flow in cardiogenic and hemorrhagic shock in awake dogs.
    Circulatory shock, 1982, Volume: 9, Issue:1

    Topics: Animals; Consciousness; Dogs; Liver Circulation; Myocardial Infarction; Phenoxybenzamine; Portal Sys

1982
Cardiovascular adrenoreceptor function during compensatory and decompensatory hemorrhagic shock.
    Circulatory shock, 1984, Volume: 12, Issue:1

    Topics: Animals; Hemodynamics; Levulinic Acids; Male; Phenoxybenzamine; Prazosin; Propranolol; Rats; Rats, I

1984
Evidence that a coronary alpha-adrenergic tone limits myocardial blood flow and oxygenation in acute hemorrhagic hypotension.
    Circulatory shock, 1983, Volume: 11, Issue:4

    Topics: Animals; Coronary Circulation; Coronary Vessels; Dogs; Female; Hypotension; Male; Myocardium; Oxygen

1983
Vascular and metabolic effects of methylprednisolone and phenoxybenzamine during controlled hypotension in the dog.
    Acta anaesthesiologica Scandinavica, 1981, Volume: 25, Issue:3

    Topics: Animals; Dogs; Hydrogen-Ion Concentration; Hypotension, Controlled; Lactates; Lactic Acid; Male; Met

1981
Effects of hydrocortisone, phenoxybenzamine and propranolol on the blood plasma levels of adrenaline and noradrenaline during hemorrhagic hypotension in the dog.
    Acta anaesthesiologica Scandinavica, 1980, Volume: 24, Issue:2

    Topics: Animals; Blood Volume; Cardiac Output; Dogs; Epinephrine; Female; Heart Rate; Hydrocortisone; Male;

1980
Vascular and hematologic effects of hemorrhage in the chicken.
    The American journal of physiology, 1981, Volume: 240, Issue:1

    Topics: Acid-Base Equilibrium; Animals; Blood Glucose; Chickens; Electrolytes; Extracellular Space; Female;

1981
Adrenergic antagonists reduce lactic acidosis in response to hemorrhagic shock.
    The Journal of trauma, 1999, Volume: 46, Issue:5

    Topics: Acidosis, Lactic; Adrenergic alpha-Antagonists; Adrenergic Antagonists; Adrenergic beta-Antagonists;

1999
Mesenteric vasoconstriction in response to hemorrhagic shock.
    Shock (Augusta, Ga.), 2000, Volume: 13, Issue:4

    Topics: Animals; Blood Pressure; Enalapril; Female; Hemodynamics; Male; Phenoxybenzamine; Regional Blood Flo

2000
Adrenergic blockade reduces skeletal muscle glycolysis and Na(+), K(+)-ATPase activity during hemorrhage.
    The Journal of surgical research, 2001, Volume: 99, Issue:2

    Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Ga

2001
The adrenergic mechanism of the haemodynamic effects of massive doses of hydrocortisone in controlled haemorrhagic shock in the dog.
    Acta anaesthesiologica Scandinavica, 1978, Volume: 22, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Fem

1978
Haemodynamic effects of different corticosteroids in controlled haemorrhagic shock in the dog.
    Acta anaesthesiologica Scandinavica, 1978, Volume: 22, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Aldosterone; Animals; Betamethasone; Cardiac

1978
[Therapy of so-called shock lung. Experimental animal studies of the lung in shock].
    Fortschritte der Medizin, 1979, Apr-26, Volume: 97, Issue:16

    Topics: Animals; Blood Transfusion, Autologous; Dogs; Hemodilution; Hemodynamics; Methylprednisolone; Oxygen

1979
Effects of alpha-adrenergic blockade on coronary blood flow of dogs in hemorrhagic shock.
    Circulatory shock, 1977, Volume: 4, Issue:4

    Topics: Animals; Blood Flow Velocity; Coronary Circulation; Dogs; Male; Phenoxybenzamine; Shock, Hemorrhagic

1977
Effects of alpha-adrenergic blockade on renal function in hemorrhagic shock.
    The American journal of physiology, 1977, Volume: 232, Issue:5

    Topics: Animals; Diuresis; Dogs; Female; Glomerular Filtration Rate; Kidney; Male; Osmolar Concentration; Ph

1977
Haemodynamic effects of massive doses of hydrocortisone and the interaction with phenoxybenzamine in controlled haemorrhagic shock in the dog.
    Acta anaesthesiologica Scandinavica, 1976, Volume: 20, Issue:4

    Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Drug Interactions; Female; Heart Rate; Hemodynamics;

1976
[Experimental study on hemorrhagic shock--with special reference to infusion fluid, blood perfusion, dexamethasone, phenoxybenzamine and left cardiac hemodynamics].
    Masui. The Japanese journal of anesthesiology, 1976, Volume: 25, Issue:12

    Topics: Animals; Blood Transfusion, Autologous; Cardiac Output; Dexamethasone; Dogs; Hemodynamics; Perfusion

1976
Role of adipose tissue in free fatty acid metabolism in hemorrhagic hypotension and shock.
    Metabolism: clinical and experimental, 1975, Volume: 24, Issue:7

    Topics: Adipose Tissue; Animals; Arteries; Dogs; Fatty Acids, Nonesterified; Hemorrhage; Hypotension; Phenox

1975
Intramyocardial distribution of blood flow in hemorrhagic shock in anesthetized dogs.
    The American journal of physiology, 1976, Volume: 230, Issue:1

    Topics: Animals; Blood Pressure; Body Water; Cardiac Output; Coronary Circulation; Dogs; Heart Rate; Hematoc

1976
Cardiovascular mechanisms of thyrotropin-releasing hormone against experimental hemorrhagic shock.
    Circulatory shock, 1992, Volume: 36, Issue:3

    Topics: Animals; Aorta; Blood Pressure; Dopamine; Epinephrine; Heart Atria; Hemodynamics; In Vitro Technique

1992
Role of the autonomic nervous system in mediating the response to naloxone in canine hemorrhagic shock.
    Circulatory shock, 1985, Volume: 16, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Nervous System; Blood

1985
Hemodynamic effects of high doses of corticosteroids.
    Acta chirurgica Scandinavica. Supplementum, 1985, Volume: 526

    Topics: Adrenal Cortex Hormones; Animals; Bretylium Compounds; Cardiac Output; Dogs; Hemodynamics; Hexametho

1985
Liver blood flow during haemorrhagic shock in the dog treated with phenoxybenzamine.
    Acta physiologica Hungarica, 1987, Volume: 70, Issue:1

    Topics: Acidosis; Animals; Dogs; Female; Liver; Male; Phenoxybenzamine; Regional Blood Flow; Shock, Hemorrha

1987
Renal vascularity in the dog--alpha-adrenergic blockade and acute hemorrhage.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1973, Volume: 119, Issue:4

    Topics: Adrenergic alpha-Antagonists; Angiography; Animals; Blood Pressure; Blood Transfusion, Autologous; D

1973
Comparative physiology of hemorrhage. A study of adrenergic receptor stimulation and blockade in pigeon and mammal.
    Advances in experimental medicine and biology, 1972, Volume: 33, Issue:0

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Benzyl Compounds; Blood Pressure

1972
Effect of hemorrhagic shock on gluconeogenesis, oxygen consumption and redox state of perfused rat liver.
    Advances in experimental medicine and biology, 1972, Volume: 33, Issue:0

    Topics: Animals; Dinitrophenols; Flavoproteins; Fluorometry; Gluconeogenesis; Glucose; Lactates; Liver; Male

1972
Metabolic changes in hemorrhagic shock.
    Advances in experimental medicine and biology, 1971, Volume: 23, Issue:0

    Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Animals; Dogs; Fatty Acids, Nonesterified; Gluconeogen

1971
Central venous pressure and blood volume determinations after alpha-adrenergic blockade in experimental posthemorrhagic shock in dogs.
    Surgery, 1968, Volume: 64, Issue:6

    Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Blood Pressure Determination; Blood Volume; Blood

1968
Hypovolemic shock: microcirculatory changes during and after specific therapy.
    Annals of surgery, 1969, Volume: 169, Issue:5

    Topics: Angiotensin II; Animals; Blood Circulation; Blood Preservation; Blood Transfusion; Capillaries; Dogs

1969
Pathogenesis of redistribution of intrarenal blood flow in haemorrhagic hypotension.
    European journal of clinical investigation, 1971, Volume: 1, Issue:4

    Topics: Acetylcholine; Angiotensin II; Animals; Autoradiography; Blood Flow Velocity; Dogs; Hypotension; Isc

1971
Profile of circulating vasoactive substances in hemorrhagic shock and their pharmacologic manipulation.
    The Journal of clinical investigation, 1974, Volume: 54, Issue:4

    Topics: Angiotensin II; Animals; Blood Pressure; Carotid Arteries; Catecholamines; Dogs; Hemodynamics; Indom

1974
Clinical management of the patient in shock. Neurolept analgesia.
    Clinical anesthesia, 1965, Volume: 2

    Topics: Anesthesia; Benperidol; Female; Fentanyl; Humans; Isoproterenol; Middle Aged; Neuroleptanalgesia; Ph

1965
The action of certain haloalkylamines on some biological activities of bradykinin.
    British journal of pharmacology, 1969, Volume: 36, Issue:3

    Topics: Animals; Blood Pressure; Bradykinin; Drug Synergism; Ear, External; Histamine; Histamine H1 Antagoni

1969
Optimum level of combined adrenergic blockade for the experimental study of hemorrhagic shock.
    Experientia, 1969, Aug-15, Volume: 25, Issue:8

    Topics: Acid-Base Equilibrium; Acidosis; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis

1969
Mechanisms of change in thoracic duct lymph flow during hypotensive states.
    Annals of surgery, 1970, Volume: 171, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aspirin; Capillary Permeability;

1970
Blood flow, oxygen consumption, and free fatty acid release in subcutaneous adipose tissue during hemorrhagic shock in control and phenoxybenzamine-treated dogs.
    Circulation research, 1970, Volume: 26, Issue:6

    Topics: Adipose Tissue; Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Denervation; Dogs; Fatty

1970
Nature of cardiovascular decompensation during hemorrhagic hypotension.
    The American journal of physiology, 1970, Volume: 219, Issue:5

    Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Blood Pressure; Blood Proteins; Blood Volume; Dogs;

1970
Changes in pre- and postcapillary resistance in pathogenesis of hemorrhagic shock.
    The American journal of physiology, 1970, Volume: 219, Issue:5

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Atropine; Blood Pressure; Blood Proteins; Capillary Fr

1970
Response to dextran in posthemorrhagic shock after combined adrenergic receptor blockade.
    Journal of applied physiology, 1971, Volume: 30, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arteries; Blood Flow Velocity; B

1971
Simple and combined adrenergic receptor blockade in canine endotoxinemia.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1971, Volume: 3, Issue:5

    Topics: Acid-Base Equilibrium; Adrenal Glands; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; An

1971
Enhanced ventricular function after beta-blockade in hemorrhagic shock.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 186, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Aorta; Blood Pressure; Blood Volume; Dogs; Heart Rate; Heart V

1970
Shock lung.
    International surgery, 1973, Volume: 58, Issue:5

    Topics: Adolescent; Adult; Aged; Animals; Disseminated Intravascular Coagulation; Dogs; Female; Heart Failur

1973
[Treatment of renal vasospasm in shock (author's transl)].
    Urologia internationalis, 1973, Volume: 28, Issue:3

    Topics: Angiography; Animals; Cadaver; Dogs; Humans; Kidney; Kidney Transplantation; Papaverine; Phenoxybenz

1973
Bone circulation in hemorrhagic shock. An experimental study.
    The Journal of bone and joint surgery. American volume, 1972, Volume: 54, Issue:6

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Bone and Bones; Central Venous Pressure; Dogs; Electri

1972
Evaluation of dibenzyline in the treatment of irreversible experimental hemorrhagic shock.
    The Indian journal of medical research, 1972, Volume: 60, Issue:3

    Topics: Animals; Blood Pressure; Blood Transfusion; Central Venous Pressure; Cerebral Ventricles; Dogs; Fema

1972
Adipose tissue and hemorrhagic shock.
    Advances in experimental medicine and biology, 1972, Volume: 33, Issue:0

    Topics: Adipose Tissue; Animals; Dogs; Electric Stimulation; Epinephrine; Fatty Acids, Nonesterified; Glycer

1972
Effect of glucagon on survival time of dogs in hemorrhagic shock.
    Research communications in chemical pathology and pharmacology, 1972, Volume: 4, Issue:1

    Topics: Animals; Blood Pressure; Dogs; Drug Interactions; Female; Glomerular Filtration Rate; Glucagon; Hema

1972
[Effects of phenoxybenzamine (POB) on the heart and circuratory system and its application to open heart surgery].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1973, Volume: 21, Issue:9

    Topics: Animals; Cardiac Surgical Procedures; Dogs; Hemodynamics; Humans; Phenoxybenzamine; Shock, Hemorrhag

1973
[Drugs in shock treatment].
    Der Internist, 1971, Volume: 12, Issue:3

    Topics: Adrenal Cortex Hormones; Cardiac Output; Chlorpromazine; Digitalis Glycosides; Humans; Isoproterenol

1971
Experimental hemorrhagic shock: 1. Pharmacologic effect of phenoxybenzamine and epinephrine on the small vessels and microcirculation.
    Military medicine, 1969, Volume: 134, Issue:3

    Topics: Animals; Blood Circulation; Capillaries; Dogs; Epinephrine; Female; Male; Phenoxybenzamine; Shock, H

1969
Preliminary studies on the effect of adrenergic blockade on haemorrhage-induced changes in blood coagulability and fibrinolysis.
    The British journal of surgery, 1972, Volume: 59, Issue:4

    Topics: Animals; Blood Coagulation; Catecholamines; Fibrinolysis; Phenoxybenzamine; Propranolol; Sheep; Shoc

1972
Arterio-venous anastomoses in the kidney. X. Effect of phenoxybenzamine on intrarenal circulation of dogs in tourniquet shock.
    Acta physiologica Academiae Scientiarum Hungaricae, 1971, Volume: 40, Issue:2

    Topics: Animals; Arteriovenous Anastomosis; Blood Flow Velocity; Blood Pressure; Cardiac Output; Dogs; Injec

1971
Combined adrenergic receptor blockade and circulating catecholamines in hemorrhagic shock.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1971, Volume: 3, Issue:6

    Topics: Animals; Blood Flow Velocity; Blood Pressure Determination; Carbon Dioxide; Cardiac Output; Catechol

1971
[Effects of endotoxic shock on blood coagulation--with special reference to thrombelastogram].
    Masui. The Japanese journal of anesthesiology, 1971, Volume: 20, Issue:12

    Topics: Animals; Blood Coagulation; Dogs; Hydrocortisone; Phenoxybenzamine; Shock, Hemorrhagic; Shock, Septi

1971
Microcirculation of dogs in hemorrhagic shock and after treatment.
    Archives of surgery (Chicago, Ill. : 1960), 1968, Volume: 96, Issue:2

    Topics: Animals; Blood Cells; Cell Aggregation; Dogs; Epinephrine; Female; Fluid Therapy; Male; Microcircula

1968
The effect on muscle glycogen of shock due to spinal cord destruction and of haemorrhagic shock with peripheral denervation.
    Quarterly journal of experimental physiology and cognate medical sciences, 1966, Volume: 51, Issue:4

    Topics: Animals; Blood Glucose; Cordotomy; Denervation; Glucose Oxidase; Glycogen; Lactates; Muscles; Phenox

1966
The function of the central nervous system after haemorrhage.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1970, Volume: 4

    Topics: Acid-Base Equilibrium; Animals; Blood Flow Velocity; Blood Pressure; Brain; Brain Chemistry; Carbon

1970
Effect of dopa on the catecholamine content of dog heart after hemorrhagic hypotension.
    Japanese journal of pharmacology, 1965, Volume: 15, Issue:4

    Topics: Animals; Dihydroxyphenylalanine; Dogs; Epinephrine; Heart; Hypotension; In Vitro Techniques; Myocard

1965
The management of massive gastrointestinal bleeding in the aged patient.
    Geriatrics, 1967, Volume: 22, Issue:3

    Topics: Aged; Blood Volume Determination; Cardiovascular Diseases; Cerebrovascular Disorders; Chromium Isoto

1967
[163. Intestinal factors in shock: intestinal circulation].
    Langenbecks Archiv fur Chirurgie, 1967, Volume: 319

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Chlorpromazine; Dogs; Gastrointestinal Hemorrhage; Hyp

1967
[Various clinical considerations on shock].
    Minerva anestesiologica, 1970, Volume: 36, Issue:12

    Topics: Animals; Antifibrinolytic Agents; Aprotinin; Disease Models, Animal; Dogs; Glucocorticoids; Humans;

1970
Comparative effect of prophylactic administration of isoxsuprine hydrochloride and phenoxybenzamine hydrochloride on the survival rate of dogs subjected to acute blood loss.
    The Indian journal of medical research, 1969, Volume: 57, Issue:10

    Topics: Amino Alcohols; Animals; Blood Pressure Determination; Dogs; Female; Male; Phenoxybenzamine; Shock,

1969
Cardiac and renal blood flow. Comparison of the effects of isoproterenol, phenozybenzamine, and levarterenol.
    Archives of surgery (Chicago, Ill. : 1960), 1970, Volume: 100, Issue:3

    Topics: Animals; Blood Transfusion; Coronary Vessels; Dogs; Isoproterenol; Kidney; Methods; Norepinephrine;

1970
The effect of phenoxybenzamine on muscle blood-flow and lactic acidosis in haemorrhagic shock in dogs.
    The British journal of surgery, 1970, Volume: 57, Issue:5

    Topics: Acidosis; Animals; Blood Pressure; Dogs; Lactates; Muscles; Phenoxybenzamine; Shock, Hemorrhagic; So

1970
Effect of drug therapy of hemorrhagic hypotension on kinetics of peritoneal dialysis in the dog.
    Nephron, 1970, Volume: 7, Issue:2

    Topics: Animals; Biological Transport; Dogs; Hypotension, Controlled; Injections, Intravenous; Norepinephrin

1970
The effect of noradrenaline and phenoxybenzamine on the renal response to hemorrhage.
    Surgery, gynecology & obstetrics, 1970, Volume: 130, Issue:5

    Topics: Animals; Blood Pressure; Disease Models, Animal; Dogs; Hemorrhage; Injections, Intravenous; Kidney;

1970
The dilemma of vasopressors and vasodilators in the therapy of shock.
    Surgery, gynecology & obstetrics, 1971, Volume: 132, Issue:1

    Topics: Blood Pressure; Cardiac Output; Central Venous Pressure; Chlorpromazine; Heart Rate; Hemodynamics; H

1971
[The use of sympathomimetics and sympatholytics in shock].
    Duodecim; laaketieteellinen aikakauskirja, 1971, Volume: 87, Issue:4

    Topics: Chlorpromazine; Dopamine; Humans; Isoproterenol; Metaraminol; Norepinephrine; Phenoxybenzamine; Phen

1971
Tissue perfusion and lactic acidosis in haemorrhagic shock: an experimental study.
    Annals of the Royal College of Surgeons of England, 1971, Volume: 48, Issue:2

    Topics: Acidosis; Animals; Blood Circulation; Blood Transfusion, Autologous; Constriction; Dogs; Epinephrine

1971
Indications for adrenergic stimulators in shock.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:4

    Topics: Blood Pressure; Blood Volume; Cardiac Output; Carotid Arteries; Central Venous Pressure; Cerebrovasc

1971
[Halothane as an anti-adrenergic drug in the treatment of shock. Experimental hemodynamic study].
    Minerva anestesiologica, 1967, Volume: 33, Issue:1

    Topics: Animals; Blood Transfusion; Dogs; Halothane; Hemodynamics; Phenoxybenzamine; Propranolol; Shock; Sho

1967
[Vaspressors or vasodilators in traumatic and hypovolemic shock].
    Klinische Medizin; osterreichische Zeitschrift fur wissenschaftliche und praktische Medizin, 1967, Volume: 22, Issue:7

    Topics: Hemodynamics; Humans; Isoproterenol; Phenoxybenzamine; Shock, Hemorrhagic; Shock, Traumatic; Vasocon

1967
[Local circulation in hemorrhagic experimental shock (study made with an electromagnetic flowmeter)].
    Acta anaesthesiologica, 1967

    Topics: Animals; Dogs; Electrocardiography; Phenoxybenzamine; Regional Blood Flow; Shock, Hemorrhagic

1967
The liver in shock. A comparison of some techniques used currently in therapy.
    The British journal of surgery, 1968, Volume: 55, Issue:5

    Topics: Animals; Blood Glucose; Dogs; Epinephrine; Hepatic Veins; Hypertonic Solutions; Hypothermia, Induced

1968
Protective effects of nylidrin and isoproterenol against hemorrhagic shock.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 161, Issue:1

    Topics: Animals; Blood Flow Velocity; Blood Volume; Carbon Dioxide; Cardiac Output; Dogs; Hematocrit; Hydrog

1968
The sympatho-adrenal factor in haemorrhagic shock.
    Annals of the Royal College of Surgeons of England, 1968, Volume: 42, Issue:6

    Topics: Acid-Base Equilibrium; Animals; Arteries; Blood Gas Analysis; Blood Pressure; Blood Volume Determina

1968
Carbon dioxide content of brain tissue and acid-base balance in haemorrhagic shock after pretreatment with dibenzyline.
    Acta medica Academiae Scientiarum Hungaricae, 1968, Volume: 25, Issue:1

    Topics: Acid-Base Equilibrium; Acidosis; Animals; Bicarbonates; Blood Pressure; Brain Chemistry; Carbon Diox

1968
Lactate studies of the dog in oligemic shock.
    The Journal of surgical research, 1968, Volume: 8, Issue:10

    Topics: Acid-Base Equilibrium; Animals; Blood Volume; Digestive System; Dogs; Lactates; Muscles; Pentaerythr

1968
The effect of adrenergic blockade upon shock-induced lacticacidosis in sheep.
    The British journal of surgery, 1968, Volume: 55, Issue:10

    Topics: Acidosis; Animals; Blood Pressure; Epinephrine; Female; Lactates; Male; Phenoxybenzamine; Propranolo

1968
Prevention of lesions of the lung secondary to hemorrhagic shock.
    Surgery, gynecology & obstetrics, 1968, Volume: 127, Issue:5

    Topics: Aminophylline; Animals; Atropine; Dogs; Lung; Phenoxybenzamine; Pulmonary Atelectasis; Replantation;

1968
[Evaluation of adrenergic blockade in hemorrhagic shock].
    Tip Fakultesi mecmuasi, 1968, Volume: 31, Issue:3

    Topics: Aged; Humans; Hypertension; Male; Middle Aged; Phenoxybenzamine; Shock, Hemorrhagic

1968
[Effect of phenoxybenzamine in renal hemodynamics].
    Tip Fakultesi mecmuasi, 1968, Volume: 31, Issue:3

    Topics: Animals; Dogs; Hemodynamics; Hypotension; Kidney; Phenoxybenzamine; Shock, Hemorrhagic

1968
[Continuous measurement of cardiac work load and its application. 2. Hemorrhagic shock].
    Masui. The Japanese journal of anesthesiology, 1968, Volume: 17, Issue:5

    Topics: Animals; Computers, Analog; Dextrans; Guinea Pigs; Heart; Heart Ventricles; Hemodynamics; Phenoxyben

1968
[Studies on the effect of 2-ethyl-3,3-diphenyl propen-(2)-yl-amine in experimental hemorrhagic and ischemic shock].
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:9

    Topics: Animals; Arteries; Blood Pressure; Blood Volume; Butylamines; Dogs; Female; Ischemia; Male; Phenoxyb

1968
Combined adrenergic blockade in experimental hemorrhagic hypotension.
    Pflugers Archiv : European journal of physiology, 1969, Jun-24, Volume: 310, Issue:1

    Topics: Animals; Blood Chemical Analysis; Blood Glucose; Blood Volume; Carbon Dioxide; Dogs; Hematocrit; Hyd

1969
Effects of adrenergic blocking agents on renal blood flow in normovolemic and moderately hypovolemic states.
    Surgical forum, 1965, Volume: 16

    Topics: Animals; Hydralazine; Kidney; Phenoxybenzamine; Shock, Hemorrhagic; Trimethaphan

1965
Effect of dibenzyline treatment on cardiac dynamics and oxidative metabolism in hemorrhagic shock.
    Annals of surgery, 1965, Volume: 162, Issue:6

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Cardiac Output; Dogs; Oxygen Consumption; Phenoxybenzam

1965
The microcirculatory and metabolic effects of dibenzyline in oligemic shock.
    Surgery, gynecology & obstetrics, 1966, Volume: 123, Issue:4

    Topics: Animals; Blood Circulation; Bloodletting; Dogs; Lactates; Phenoxybenzamine; Pyruvates; Shock, Hemorr

1966
Blood flow and oxygen consumption with adrenergic blockade in hemorrhagic shock.
    The American journal of physiology, 1966, Volume: 211, Issue:2

    Topics: Acidosis; Animals; Cardiac Output; Dogs; Hydrogen-Ion Concentration; Mesenteric Arteries; Oxygen; Ox

1966
Effects of adrenergic blocking agents on renal blood flow in normovolemia and experimental hypovolemia.
    Annals of surgery, 1966, Volume: 164, Issue:1

    Topics: Animals; Blood Circulation; Blood Flow Velocity; Blood Volume; Dogs; Hydralazine; Kidney; Phenoxyben

1966