phenoxybenzamine has been researched along with Hemorrhage in 61 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Hemorrhage: Bleeding or escape of blood from a vessel.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg/kg of phenoxybenzamine) enhanced the maintenance of cerebral blood flow in the face of hemorrhagic hypotension in that cerebral blood flow did not decrease until mean arterial blood pressure was approximately 35% of the base-line value." | 3.65 | Effects of decreasing arterial blood pressure on cerebral blood flow in the baboon. Influence of the sympathetic nervous system. ( Fitch, W; Harper, AM; MacKenzie, ET, 1975) |
| "In order to investigate the possible role of the renin-angiotensin system in the regulation of intrarenal hemodynamics in hemorrhagic hypotension (HH), seven mongrel dogs have been studied under the following conditions: (a) Control, (b) HH (mean arterial pressure 70 mm Hg), and (c) HH + alpha adrenergic blockade by phenoxybenzamine (HH + POB)." | 3.65 | Relationship between renin and intrarenal hemodynamics in hemorrhagic hypotension. ( Grandchamp, A; Rosset, E; Scherrer, JR; Truniger, B; Veyrat, R, 1971) |
| " Pretreatment with phenoxybenzamine, phentolamine, propranolol, or atropine did not alter the redistribution of cortical flow during hemorrhage." | 3.65 | Mechanism of the redistribution of renal cortical blood flow during hemorrhagic hypotension in the dog. ( Boonjarern, S; Ferris, TF; Mauk, RC; Stein, JH, 1973) |
| "Propranolol infusion at a lower rate (0." | 1.28 | Dual adrenergic control of renin during nonhypotensive hemorrhage in conscious dogs. ( Blair, ML; Gengo, FM; Hisa, H; Radke, KJ; Sladek, CD, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 59 (96.72) | 18.7374 |
| 1990's | 2 (3.28) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MILLAR, RA | 1 |
| KEENER, EB | 1 |
| BENFEY, BG | 1 |
| KALAS, JP | 1 |
| JACOBSON, ED | 2 |
| LEVIN, J | 1 |
| CLUFF, LE | 1 |
| MURPHY, GP | 1 |
| GAGNON, JA | 1 |
| EWALD, RA | 1 |
| Smith, LL | 2 |
| Rittmann, WW | 2 |
| Dow, RW | 1 |
| Fry, WJ | 1 |
| Müller-Berghaus, G | 2 |
| McKay, DG | 1 |
| Cooper, D | 1 |
| Skillman, JJ | 1 |
| Ciampa, GR | 1 |
| Edwards, EA | 1 |
| Nagy, S | 1 |
| Tárnoky, K | 1 |
| Petri, G | 1 |
| Tyler, DC | 1 |
| Nessly, M | 1 |
| Cheney, FW | 1 |
| Stone, DN | 2 |
| Dujardin, JP | 2 |
| Houck, PC | 1 |
| Lutherer, LO | 1 |
| McCafferty, JP | 1 |
| Roesler, JM | 1 |
| Pendleton, RG | 1 |
| Ploucha, JM | 1 |
| Scott, JB | 1 |
| Ringer, RK | 1 |
| Henrich, WL | 1 |
| Pettinger, WA | 1 |
| Cronin, RE | 1 |
| Rudé, MJ | 1 |
| Soucy, DM | 1 |
| Hagedorn, F | 1 |
| Illner, H | 1 |
| Shires, GT | 1 |
| Fitch, W | 1 |
| MacKenzie, ET | 1 |
| Harper, AM | 1 |
| Gagov, S | 1 |
| Fukuda, T | 1 |
| Salgado, HC | 1 |
| Krieger, EM | 1 |
| Rawe, SE | 1 |
| Roth, RH | 1 |
| Collins, WF | 1 |
| Anderson, WP | 1 |
| Ludbrook, J | 1 |
| Powers, JC | 1 |
| Shaftan, GW | 1 |
| Herbsman, H | 1 |
| Kashyap, ML | 1 |
| Tay, JS | 1 |
| Sothy, SP | 1 |
| Morrison, JA | 1 |
| Petrov, L | 1 |
| Blair, ML | 1 |
| Hisa, H | 1 |
| Sladek, CD | 1 |
| Radke, KJ | 1 |
| Gengo, FM | 1 |
| Osterholm, JL | 2 |
| Kovách, AG | 1 |
| Mitsányi, A | 1 |
| Monos, E | 1 |
| Nyáry, I | 1 |
| Sulyok, A | 1 |
| Bugge-Asperheim, B | 1 |
| Kjekshus, J | 1 |
| Bond, RF | 1 |
| Lackey, GF | 1 |
| Taxis, JA | 1 |
| Green, HD | 1 |
| McNeill, JR | 2 |
| Stark, RD | 2 |
| Greenway, CV | 2 |
| Grandchamp, A | 1 |
| Veyrat, R | 1 |
| Rosset, E | 1 |
| Scherrer, JR | 1 |
| Truniger, B | 1 |
| DuCharme, DW | 1 |
| Beck, L | 1 |
| Chen, HI | 1 |
| Chai, CY | 1 |
| Ross, EJ | 1 |
| Prichard, BN | 1 |
| Kaufman, L | 1 |
| Robertson, AI | 1 |
| Harries, BJ | 1 |
| Moss, AJ | 1 |
| Schenk, EA | 1 |
| Brobmann, GF | 1 |
| Ulano, HB | 1 |
| Moore, G | 1 |
| Meyer, P | 1 |
| Brecher, GA | 1 |
| Lis, M | 1 |
| Kovacs, K | 1 |
| Story, ME | 1 |
| Bentley, GA | 1 |
| Huang, WC | 1 |
| Lee, RS | 1 |
| Young, TK | 1 |
| Sooriyamoorthy, T | 1 |
| Livingston, A | 1 |
| Takács, L | 1 |
| Kenéz, B | 1 |
| Albert, K | 1 |
| Nomoto, S | 1 |
| Nakayama, R | 1 |
| Tokura, Y | 1 |
| Kimura, Y | 1 |
| Stein, JH | 1 |
| Boonjarern, S | 1 |
| Mauk, RC | 1 |
| Ferris, TF | 1 |
| Mathews, GJ | 1 |
| Irvin, JD | 1 |
| Calesnick, B | 1 |
| Zeig, NJ | 1 |
| Buckley, NM | 1 |
| Macy, J | 1 |
| Beard, J | 1 |
| Järhult, J | 1 |
| Lundvall, J | 1 |
| Mellander, S | 1 |
| Tibblin, S | 1 |
| Cherniack, NS | 1 |
| Edelman, NH | 1 |
| Fishman, AP | 1 |
| Marston, A | 1 |
| Nash, CB | 2 |
| Smith, RD | 1 |
| Bell, G | 1 |
| Lister, GD | 1 |
| Carrière, S | 1 |
| Daigneault, B | 1 |
| Taguchi, K | 1 |
| Matsuura, Y | 1 |
| Nakai, H | 1 |
| Nakamura, S | 1 |
| Yoshizaki, E | 1 |
| Lawson, AE | 1 |
| Gump, FE | 1 |
| Magill, T | 1 |
| Thal, AP | 1 |
| Kinney, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cerebral Blood Flow Evaluation With Trancranial Doppler After Unilateral Interscalene Nerve Block: Observational Prospective Study[NCT04642612] | 10 participants (Actual) | Observational | 2021-03-04 | Terminated (stopped due to Study not properly designed for outcome measure) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for phenoxybenzamine and Hemorrhage
| Article | Year |
|---|---|
Noradrenergic mediation of traumatic spinal cord autodestruction.
Topics: Animals; Apomorphine; Carboxy-Lyases; Cats; Disulfides; Dopamine beta-Hydroxylase; Hemorrhage; Imida | 1974 |
[On the physiopathology of the consumption coagulopathy].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antigen-Antibody Reactions; Blood Coagulation | 1969 |
Venous pressure and other thoughts.
Topics: Anesthesia; Blood Pressure; Blood Volume Determination; Cardiac Output; Catecholamines; Chlorpromazi | 1969 |
58 other studies available for phenoxybenzamine and Hemorrhage
| Article | Year |
|---|---|
Plasma adrenaline and noradrenaline after phenoxybenzamine administration, and during haemorrhagic hypotension, in normal and adrenalectomized dogs.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Dogs; Epinephrine; Hemorrhage; Hypotension; Norepinephrine; | 1959 |
THE EFFECT OF VASOACTIVE ANTAGONISTS IN ENDOTOXIN SHOCK.
Topics: Animals; Atropine; Blood Circulation; Blood Pressure; Blood Pressure Determination; Chloralose; Cypr | 1964 |
ENDOTOXEMIA AND ADRENAL HEMORRHAGE. A MECHANISM FOR THE WATERHOUSE-FRIDERICHSEN SYNDROME.
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Animals; Blood; Blood Coagulation Tests; Cortis | 1965 |
RENAL AND SYSTEMIC HEMODYNAMIC EFFECTS OF DIBENZYLINE IN NORMOTENSION AND HEMORRHAGIC HYPOTENSION.
Topics: Animals; Blood Circulation; Blood Pressure; Blood Volume; Dogs; Hemodynamics; Hemorrhage; Hypotensio | 1965 |
Cerebral blood flow changes following severe hemorrhage and treatment.
Topics: Animals; Blood Flow Velocity; Blood Transfusion; Blood Volume Determination; Cardiac Output; Cerebro | 1967 |
Venous compensatory mechanisms in acute hypovolemia.
Topics: Animals; Blood Circulation; Blood Flow Velocity; Blood Pressure; Blood Volume; Chlorpromazine; Dogs; | 1967 |
Prevention of the generalized Shwartzman reaction in pregnant rats by alpha-adrenergic blocking agents.
Topics: Animals; Catecholamines; Dibenzylchlorethamine; Endotoxins; Female; Hemorrhage; Kidney Glomerulus; L | 1967 |
External pulse recording in experimental hemorrhage and drug infusion in man.
Topics: Adult; Blood Pressure; Blood Volume; Cardiac Output; Cardiovascular System; Hemodynamics; Hemorrhage | 1967 |
Cardiac output and oxygen uptake after haemorrhage in conscious dogs under sympathetic alpha-receptor blockade.
Topics: Animals; Blood Pressure; Cardiac Catheterization; Cardiac Output; Dogs; Hemorrhage; Oxygen Consumpti | 1967 |
Reflex responses to positive end-expiratory pressure.
Topics: Animals; Atropine; Blood Pressure; Cardiac Output; Hemorrhage; Phenoxybenzamine; Positive-Pressure R | 1984 |
Changes in smooth muscle tone influence characteristic impedance of the aorta.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Blood Volume; Cardiography, Impedance; Dogs; Hemorrhage; M | 1984 |
The effects of phenoxybenzamine on the aortic pressure-diameter relationship in dogs.
Topics: Animals; Aorta; Blood Pressure; Blood Volume; Dogs; Hemorrhage; Male; Phenoxybenzamine | 1982 |
Regulation of adrenal blood flow: response to hemorrhagic hypotension.
Topics: Adrenal Glands; Animals; Blood Pressure; Dogs; Female; Hemorrhage; Histamine; Homeostasis; Hypophyse | 1981 |
Studies on the mechanisms involved in the cardiovascular response of the rat to hemorrhage.
Topics: Adrenal Medulla; Animals; Atropine; Blood Pressure; Heart Rate; Hemorrhage; Isoquinolines; Male; Mon | 1981 |
Vascular and hematologic effects of hemorrhage in the chicken.
Topics: Acid-Base Equilibrium; Animals; Blood Glucose; Chickens; Electrolytes; Extracellular Space; Female; | 1981 |
The influence of circulating catecholamines and prostaglandins on canine renal hemodynamics during hemorrhage.
Topics: Animals; Blood Pressure; Cardiac Output; Catecholamines; Dogs; Glomerular Filtration Rate; Hemodynam | 1981 |
The effect of sympatholytics on uncontrolled hemorrhage.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Drug The | 1999 |
Effects of decreasing arterial blood pressure on cerebral blood flow in the baboon. Influence of the sympathetic nervous system.
Topics: Adrenergic alpha-Antagonists; Animals; Blood; Blood Pressure; Blood Transfusion; Carbon Dioxide; Cer | 1975 |
Reactions of the arterial blood pressure in changed haemodynamic conditions and under the effect of bilateral carotid occlusion.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Carotid Arteries; Cats; Hemodynamics; Hemorrh | 1975 |
Arteriovenous difference of plasma osmolality and osmoactive substances in the hind limb of dogs under hemorrhagic hypotension--special reference to endogenous catecholamine--.
Topics: Animals; Arteries; Bicarbonates; Blood; Blood Glucose; Blood Pressure; Bloodletting; Catecholamines; | 1977 |
Time course of baroreceptor resetting in short-term hypotension in the rat.
Topics: Adaptation, Physiological; Animals; Female; Hemorrhage; Hypotension; Male; Phenoxybenzamine; Pressor | 1978 |
Norepinephrine levels in experimental spinal cord trauma. Part 2: Histopathological study of hemorrhagic necrosis.
Topics: Animals; Blood Pressure; Cats; Hemorrhage; Methyltyrosines; Necrosis; Norepinephrine; Phenoxybenzami | 1977 |
Effects of the sympathetic nervous system and the adrenal medullary hormones on dog hind limb blood flow after haemorrhage.
Topics: Animals; Blood Pressure; Catecholamines; Dogs; Hemorrhage; Hindlimb; Phenoxybenzamine; Regional Bloo | 1976 |
Evaluation of various hypotensive agents in the control of experimental hemorrhage.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Chlorpromazine; Diazoxide; Dogs; Drug Evaluation, | 1975 |
Role of adipose tissue in free fatty acid metabolism in hemorrhagic hypotension and shock.
Topics: Adipose Tissue; Animals; Arteries; Dogs; Fatty Acids, Nonesterified; Hemorrhage; Hypotension; Phenox | 1975 |
Reactivity and participation of the vascular bed of a limb in the compensatory vasoconstriction during haemorrhage.
Topics: Animals; Blood Pressure; Carotid Arteries; Cats; Hemorrhage; Hindlimb; Muscles; Papaverine; Phenoxyb | 1975 |
Dual adrenergic control of renin during nonhypotensive hemorrhage in conscious dogs.
Topics: Aldosterone; Animals; Arginine Vasopressin; Blood Pressure; Dogs; Epinephrine; Heart Rate; Hemorrhag | 1991 |
Control of organ blood flow following hemorrhage.
Topics: Adipose Tissue; Adrenal Glands; Animals; Atropine; Blood Circulation; Blood Pressure; Bloodletting; | 1972 |
Left ventricular pressure and maximum rate of pressure rise as determinants of myocardial oxygen consumption during hemorrhagic hypotension in dogs.
Topics: Angiotensin II; Animals; Blood Pressure; Dogs; Hemorrhage; Myocardium; Norepinephrine; Oxygen Consum | 1970 |
Factors governing cutaneous vasoconstriction during hemorrhage.
Topics: Angiotensin II; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Dogs; Hemorrhage; Kidney; Perfu | 1970 |
Intestinal vasoconstriction after hemorrhage: roles of vasopressin and angiotensin.
Topics: Adrenal Glands; Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Cats; Denervation; Hem | 1970 |
Relationship between renin and intrarenal hemodynamics in hemorrhagic hypotension.
Topics: Angiotensin II; Animals; Autoradiography; Dogs; Glomerular Filtration Rate; Hemorrhage; Hypotension; | 1971 |
The relative effect of the renal pressor and sympathetic nervous systems on vascular capacity during hypotension.
Topics: Anesthesia, Spinal; Angiotensin II; Animals; Blood Pressure; Dogs; Female; Hematocrit; Hemorrhage; H | 1971 |
Pulmonary adema and hemorrhage as a consequence of systemic vasoconstriction.
Topics: Angiotensin II; Animals; Bradykinin; Epinephrine; Hemorrhage; Hexamethonium Compounds; Histamine; Hy | 1974 |
Role of vasopressin and angiotensin in response of splanchnic resistance vessels to hemorrhage.
Topics: Abdomen; Adrenal Glands; Angiotensin II; Animals; Blood Pressure; Blood Vessels; Cats; Denervation; | 1971 |
Preoperative and operative management of patients with phaeochromocytoma.
Topics: Adolescent; Adult; Anesthetics; Arrhythmias, Cardiac; Blood Pressure; Blood Volume; Child; Ethanolam | 1967 |
Cardiovascular effects of sustained norepinephrine infusions in dogs. IV. Previous treatment with adrenergic blocking agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiac Output; | 1970 |
Effect of acute hemorrhage on arterial and venous resistance.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Arteries; Blood Flow Velocity; Blood Pressure; Blood V | 1971 |
Inhibition by adrenergic blockers of hemorrhagic necrosis in the rat's heart.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Female; Heart Diseases; Hemorrha | 1970 |
The effects of drugs and treatments upon adrenaline re-reversal in the rabbit.
Topics: Animals; Blood Pressure; Bretylium Compounds; Cocaine; Diphenhydramine; Ear; Epinephrine; Female; Gu | 1974 |
Depletion of neurohypophysial vasopressin content in rats following hemorrhage.
Topics: Animals; Blood Pressure; Female; Hemorrhage; Hypotension; Male; Phenoxybenzamine; Phentolamine; Pitu | 1974 |
Blood flow changes in the pituitary neural lobe of the rabbit associated with neurohypophysial hormone-releasing stimuli.
Topics: Animals; Atropine; Blood Pressure; Calcium Chloride; Female; Hemorrhage; Male; Methacholine Compound | 1973 |
Nutritive collateral circulation of the hind limb muscles in the rat.
Topics: Animals; Atropine; Cardiac Output; Collateral Circulation; Dye Dilution Technique; Epinephrine; Femo | 1972 |
Effects of sympathomimetic and sympatholytic agents on mesenteric hemodynamics in hemorrhagic hypotension.
Topics: Animals; Cardiac Output; Dogs; Epinephrine; Hemodynamics; Hemorrhage; Hypotension; Isoproterenol; Me | 1972 |
Mechanism of the redistribution of renal cortical blood flow during hemorrhagic hypotension in the dog.
Topics: Animals; Aorta, Abdominal; Atropine; Blood Flow Velocity; Blood Pressure; Blood Transfusion, Autolog | 1973 |
Chapter 29. Anti-norepinephrine therapy against traumatic hemorrhagic necrosis of the spinal cord: preliminary report.
Topics: Animals; Bretylium Compounds; Cats; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Guan | 1973 |
Effects of acute hemorrhage after adrenergic blockade in splenectomized dogs.
Topics: Aminohippuric Acids; Animals; Cardiac Output; Creatinine; Dogs; Glomerular Filtration Rate; Hemorrha | 1968 |
Osmolar control of plasma volume during hemorrhagic hypotension.
Topics: Animals; Blood Flow Velocity; Blood Glucose; Capillary Permeability; Cats; Hemorrhage; Hypotension; | 1972 |
Pattern of discharge of respiratory neurons during systemic vasomotor waves.
Topics: Animals; Blood Pressure; Carbon Dioxide; Chemoreceptor Cells; Denervation; Dogs; Hemorrhage; Neurons | 1969 |
Gram-negative septicaemia--clinical aspects and physiological management.
Topics: Central Venous Pressure; Dexamethasone; Drainage; Hemorrhage; Humans; Infusions, Parenteral; Isoprot | 1969 |
Alteration of norepinephrine responses in the dog by dual adrenergic blockade.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Dogs; Female; Heart Diseases; Hematocrit; Hemorrhage; | 1969 |
The effect of noradrenaline and phenoxybenzamine on the renal response to hemorrhage.
Topics: Animals; Blood Pressure; Disease Models, Animal; Dogs; Hemorrhage; Injections, Intravenous; Kidney; | 1970 |
Effect of retransfusion after hemorrhagic hypotension on intrarenal distribution of blood flow in dogs.
Topics: Animals; Autoradiography; Blood Flow Velocity; Blood Pressure; Blood Transfusion, Autologous; Dextra | 1970 |
The effects of dibenzyline on the venous, arterial and atrial pressure in overtransfusion and hemorrhage.
Topics: Animals; Blood Pressure; Blood Transfusion; Dogs; Femoral Artery; Femoral Vein; Heart Atria; Hemorrh | 1967 |
Vascular responses of the spleen to nerve stimulation during normal and reduced blood flow.
Topics: Animals; Arteries; Atropine; Blood Flow Velocity; Blood Pressure Determination; Blood Volume Determi | 1968 |
Regional adrenergic blockade by intra-arterial injection of phenoxybenzamine.
Topics: Animals; Autonomic Nerve Block; Dogs; Hemorrhage; Hypotension; Injections, Intra-Arterial; Jugular V | 1968 |
Dual adrenergic blockade and epinephrine infusion.
Topics: Animals; Arrhythmias, Cardiac; Blood; Blood Pressure; Depression, Chemical; Dogs; Electrocardiograph | 1968 |
Effect of treatment agents on cerebral blood flow following hemorrhage.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Blood Transfusion; Cerebrovascular Circulation; Dextra | 1965 |