phenoxybenzamine has been researched along with Heart Failure in 14 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The clinical signs of congestive heart failure resolved rapidly on treatment with captopril and myocardial performance became normal within two weeks of medical treatment with captopril for one week and with captopril in combination with phenoxybenzamine for another week." | 5.28 | Rapid reversal of heart failure in a patient with phaeochromocytoma and catecholamine-induced cardiomyopathy who was treated with captopril. ( Ritz, R; Salathe, M; Weiss, P, 1992) |
| " However, there are both clinical data and theoretic reasons to anticipate that some degree of tolerance may develop during the long-term use of most agents." | 2.36 | Mechanisms and implications of vasodilator tolerance in the treatment of congestive heart failure. ( Alexander, RW; Braunwald, E; Colucci, WS; Williams, GH, 1981) |
| "The clinical signs of congestive heart failure resolved rapidly on treatment with captopril and myocardial performance became normal within two weeks of medical treatment with captopril for one week and with captopril in combination with phenoxybenzamine for another week." | 1.28 | Rapid reversal of heart failure in a patient with phaeochromocytoma and catecholamine-induced cardiomyopathy who was treated with captopril. ( Ritz, R; Salathe, M; Weiss, P, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Colucci, WS | 1 |
| Williams, GH | 1 |
| Alexander, RW | 1 |
| Braunwald, E | 1 |
| Imhof, P | 1 |
| Wosornu, L | 1 |
| Larochelle, P | 1 |
| Ogilvie, RI | 1 |
| Seneca, H | 1 |
| Salathe, M | 1 |
| Weiss, P | 1 |
| Ritz, R | 1 |
| Clauss, RH | 1 |
| Ray, JF | 1 |
| Greenway, CV | 1 |
| Murthy, VS | 1 |
| Hollenberg, NK | 1 |
| Waters, JR | 1 |
| Toews, MR | 1 |
| Davies, RO | 1 |
| Nickerson, M | 1 |
| Hardaway, RM | 1 |
| Fernandes, M | 1 |
| Kim, KE | 1 |
| Moyer, JH | 1 |
| Lambotte, L | 1 |
| Rocmans, P | 1 |
| Beard, J | 1 |
| Britt, LG | 1 |
| Cheek, RC | 1 |
5 reviews available for phenoxybenzamine and Heart Failure
| Article | Year |
|---|---|
Mechanisms and implications of vasodilator tolerance in the treatment of congestive heart failure.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Dr | 1981 |
[Treatment of cardiac failure with vasodilators (author's transl)].
Topics: Cardiac Glycosides; Diuretics; Drug Therapy, Combination; Heart Failure; Hydralazine; Hypotension; I | 1978 |
Pharmacologic assistance to the failing circulation.
Topics: Adenosine Triphosphatases; Aminophylline; Angiotensin II; Blood Gas Analysis; Blood Pressure; Cardia | 1968 |
Hypertensive emergencies.
Topics: Acute Kidney Injury; Adrenal Gland Neoplasms; Antihypertensive Agents; Aortic Aneurysm; Blood Volume | 1974 |
Venous pressure and other thoughts.
Topics: Anesthesia; Blood Pressure; Blood Volume Determination; Cardiac Output; Catecholamines; Chlorpromazi | 1969 |
9 other studies available for phenoxybenzamine and Heart Failure
| Article | Year |
|---|---|
Septic shock.
Topics: Adult; Anti-Bacterial Agents; Blood Coagulation; Digoxin; Drainage; Endotoxins; Female; Fluid Therap | 1979 |
Effect of drugs on effective vascular compliance in acute heart failure.
Topics: Acute Disease; Animals; Aorta, Thoracic; Coronary Vessels; Dogs; Ethacrynic Acid; Heart Failure; Mal | 1975 |
Gram-negative sepsis: part II. Management.
Topics: Acidosis; Adult; Amikacin; Child; Chloramphenicol; Clindamycin; Disseminated Intravascular Coagulati | 1977 |
Rapid reversal of heart failure in a patient with phaeochromocytoma and catecholamine-induced cardiomyopathy who was treated with captopril.
Topics: Acute Disease; Adrenal Gland Neoplasms; Adult; Captopril; Cardiomyopathies; Catecholamines; Drug The | 1992 |
Mesenteric vasoconstriction after endotoxin administration in cats pretreated with aspirin.
Topics: Angiotensin II; Animals; Aspirin; Blood Platelets; Blood Pressure; Cats; Endotoxins; Heart Failure; | 1971 |
Nature of cardiovascular decompensation during hemorrhagic hypotension.
Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Blood Pressure; Blood Proteins; Blood Volume; Dogs; | 1970 |
Shock lung.
Topics: Adolescent; Adult; Aged; Animals; Disseminated Intravascular Coagulation; Dogs; Female; Heart Failur | 1973 |
[Toxi-infectious shock].
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Blood Transfusion; Chlorpromazine; Digitalis G | 1973 |
Nonocclusive mesenteric vascular disease: clinical and experimental observations.
Topics: Aged; Animals; Cardiac Output; Dogs; Female; Heart Failure; Humans; Intestinal Diseases; Male; Mesen | 1969 |