phenoxybenzamine has been researched along with Glioma in 7 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenoxybenzamine was used to irreversibly block alpha 1 adrenergic receptors both in vitro in the BC3H1 cell line and in vivo in rat submaxillary glands." | 1.27 | Turnover of adrenergic receptors under normal and desensitized conditions. ( Bockaert, J; Bouhelal, R; Gozlan, H; Homburger, V; Lucas, M; Mauger, JP; Pantaloni, C; Sladeczek, F, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, XB | 1 |
| Jiang, L | 1 |
| Ding, MH | 1 |
| Chen, ZH | 1 |
| Bao, Y | 1 |
| Chen, Y | 1 |
| Sun, W | 1 |
| Zhang, CR | 1 |
| Hu, HK | 1 |
| Cai, Z | 1 |
| Lu, CY | 1 |
| Zhou, JY | 1 |
| Qian, J | 1 |
| Wu, XJ | 1 |
| Jin, WL | 1 |
| Hu, GH | 1 |
| Sladeczek, F | 2 |
| Homburger, V | 2 |
| Mauger, JP | 2 |
| Gozlan, H | 1 |
| Lucas, M | 1 |
| Bouhelal, R | 2 |
| Pantaloni, C | 1 |
| Bockaert, J | 2 |
| Shitara, N | 1 |
| McKeever, PE | 1 |
| Cummins, C | 1 |
| Smith, BH | 1 |
| Kornblith, PL | 1 |
| Hirata, F | 1 |
| Edström, A | 1 |
| Kanje, M | 1 |
| Löfgren, P | 1 |
| Walum, E | 1 |
| Schwartz, JP | 2 |
| Mermet-Bouvier, R | 1 |
| Passonneau, JV | 1 |
7 other studies available for phenoxybenzamine and Glioma
| Article | Year |
|---|---|
Anti-tumor activity of phenoxybenzamine hydrochloride on malignant glioma cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glioma; Humans; | 2016 |
Turnover of adrenergic receptors under normal and desensitized conditions.
Topics: Animals; Cell Line; Cycloheximide; Erythrocyte Membrane; Glioma; Kinetics; Phenoxybenzamine; Pindolo | 1984 |
beta-Adrenergic receptor desensitization stimulates glucose uptake in C6 rat glioma cells.
Topics: Animals; Biological Transport, Active; Cell Line; Cyclic AMP; Deoxy Sugars; Deoxyglucose; Epinephrin | 1982 |
Drug-induced alterations in morphology and level of cAMP in cultured human glioma cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Catecholamines; Cell Line; Cyclic AMP; Cycl | 1975 |
Stimulation of nerve growth factor mRNA content in C6 glioma cells by a beta-adrenergic receptor and by cyclic AMP.
Topics: Animals; Blotting, Northern; Cell Line; Colforsin; Cyclic AMP; Glioma; Isoproterenol; Molecular Weig | 1988 |
Metabolism of adrenergic receptors and adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Cell Line; Contact Inhibition; Cyclic AMP; Dihydroalprenolol; Glioma; Ha | 1987 |
Cyclic AMP-mediated induction of the cyclic AMP phosphodiesterase of C-6 glioma cells.
Topics: Animals; Bucladesine; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Induction; Glioma; | 1974 |