phenoxybenzamine has been researched along with Diabetes Insipidus in 2 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Diabetes Insipidus: A disease that is characterized by frequent urination, excretion of large amounts of dilute URINE, and excessive THIRST. Etiologies of diabetes insipidus include deficiency of antidiuretic hormone (also known as ADH or VASOPRESSIN) secreted by the NEUROHYPOPHYSIS, impaired KIDNEY response to ADH, and impaired hypothalamic regulation of thirst.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonidine, an alpha adrenergic agonist which causes a diuresis in experimental animals, was studied in unanesthetized, conscious Brattleboro rats heterozygous or homozygous for hereditary hypothalamic diabetes insipidus to determine if the diuresis was due to alpha adrenergic inhibition of antidiuretic hormone (ADH) release or to another mechanism of action." | 3.66 | Clonidine-induced diuresis in the rat: evidence for a renal site of action. ( Miller, M, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, M | 1 |
| Henderson, IW | 1 |
| Balment, RJ | 1 |
| Oliver, JA | 1 |
2 other studies available for phenoxybenzamine and Diabetes Insipidus
| Article | Year |
|---|---|
Clonidine-induced diuresis in the rat: evidence for a renal site of action.
Topics: Animals; Clonidine; Creatinine; Diabetes Insipidus; Diuresis; Electrolytes; Kidney; Male; Osmolar Co | 1980 |
Vasopressin effects on plasma renin activity in male and female rats.
Topics: Animals; Castration; Depression, Chemical; Diabetes Insipidus; Female; Hypophysectomy; Male; Phenoxy | 1978 |