phenoxybenzamine has been researched along with Decerebrate Posturing in 23 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with phenoxybenzamine accentuated the inhibitory actions of captopril and a combination of phenoxybenzamine and captopril significantly increased the ED50 without altering the maximum response." | 1.29 | Pressor responses to the alpha 1-adrenoceptor agonist cirazoline: effects of captopril, phenoxybenzamine and nifedipine. ( Tabrizchi, R; Triggle, CR, 1994) |
| " Reserpinization shifted the (-)-norephedrine dose-response curve slightly to the right, indicating that only a minor portion of its activity is due to the release of stored endogenous catecholamines." | 1.27 | Adrenergic receptor subtype activation by (+)-, (-)- and (+/-)-norephedrine in the pithed rat. ( Maher, TJ; Moya-Huff, FA, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (95.65) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SMITH, CB | 1 |
| Herman, EH | 1 |
| Barnes, CD | 2 |
| Ruffolo, RR | 2 |
| Morgan, EL | 2 |
| Messick, K | 1 |
| Goldberg, MR | 1 |
| Cavero, I | 1 |
| Lefevre-Borg, F | 1 |
| Lhoste, F | 1 |
| Sabatier, C | 1 |
| Richer, C | 1 |
| Giudicelli, JF | 1 |
| Strahlendorf, JC | 1 |
| Strahlendorf, HK | 1 |
| Kingsley, RE | 1 |
| Gintautas, J | 1 |
| Tabrizchi, R | 1 |
| Triggle, CR | 1 |
| Matsumiya, T | 1 |
| Berry, JN | 1 |
| Bell, JA | 1 |
| Key, BJ | 1 |
| Krzywoskinski, L | 1 |
| Levy, RA | 1 |
| Heimburger, M | 1 |
| Montero, MJ | 1 |
| Fougeres, V | 1 |
| Beslot, F | 1 |
| Davy, M | 1 |
| Midol-Monnet, M | 1 |
| Cohen, Y | 1 |
| Moya-Huff, FA | 1 |
| Maher, TJ | 1 |
| Timmermans, PB | 3 |
| Thoolen, MJ | 3 |
| Mathy, MJ | 1 |
| Wilffert, B | 1 |
| de Jonge, A | 1 |
| van Zwieten, PA | 2 |
| Jim, KF | 1 |
| Macia, RA | 1 |
| Matthews, WD | 1 |
| Beckeringh, JJ | 1 |
| Frederickson, RC | 1 |
| Jordan, LM | 1 |
| Phillis, JW | 1 |
| Cessi, C | 1 |
| Kadzielawa, K | 2 |
| Widy-Tyszkiewicz, E | 1 |
| Yamamoto, J | 1 |
| Sekiya, A | 1 |
| Gillis, RA | 1 |
| Quest, JA | 1 |
| Standaert, FG | 1 |
| Biscoe, TJ | 1 |
| Curtis, DR | 1 |
| Ryall, RW | 1 |
23 other studies available for phenoxybenzamine and Decerebrate Posturing
| Article | Year |
|---|---|
RELAXATION OF THE NICTITATING MEMBRANE OF THE SPINAL CAT BY SYMPATHOMIMETIC AMINES.
Topics: Acetylcholine; Animals; Cats; Decerebrate State; Epinephrine; Ergot Alkaloids; Isoproterenol; Nictit | 1963 |
Observations of drug effects on a type of spinal motor activity.
Topics: Animals; Atropine; Chlorpromazine; Decerebrate State; Motor Neurons; Muscles; Pentobarbital; Phenoxy | 1967 |
Possible relationship between receptor reserve and the differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by calcium channel antagonists in the pithed rat.
Topics: Animals; Aorta, Thoracic; Azepines; Blood Pressure; Decerebrate State; Diltiazem; Dose-Response Rela | 1984 |
Interactions of epinephrine, norepinephrine, dopamine and their corresponding alpha-methyl-substituted derivatives with alpha and beta adrenoceptors in the pithed rat.
Topics: Animals; Blood Pressure; Decerebrate State; Deoxyepinephrine; Dopamine; Dose-Response Relationship, | 1984 |
Pharmacological, hemodynamic and autonomic nervous system mechanisms responsible for the blood pressure and heart rate lowering effects of pergolide in rats.
Topics: Adrenalectomy; Animals; Antiparkinson Agents; Autonomic Nervous System; Blood Pressure; Clonidine; D | 1984 |
Facilitation of the lumbar monosynaptic reflexes by locus coeruleus stimulation.
Topics: Animals; Blood Pressure; Cats; Chlorpromazine; Decerebrate State; Electric Stimulation; Female; Halo | 1980 |
Pressor responses to the alpha 1-adrenoceptor agonist cirazoline: effects of captopril, phenoxybenzamine and nifedipine.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Captopril; Decerebrate State; Dose-Response Rela | 1994 |
The effect of intraspinal microinjection of dopamine on the C-fiber reflex in the acute decerebrate spinal cat.
Topics: Animals; Cats; Decerebrate State; Dopamine; Female; Fusaric Acid; Male; Microinjections; Nerve Fiber | 1979 |
Electrocortical changes induced by the perfusion of noradrenaline, acetylcholine and their antagonists directly into the dorsal raphé nucleus of the cat.
Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Cats; Decerebrate State; Dopamine; Electroencephal | 1977 |
The effect of intravenously administered gamma-aminobutyric acid on afferent fiber polarization.
Topics: Aminobutyrates; Animals; Bicuculline; Cats; Decerebrate State; Drug Interactions; Evoked Potentials; | 1975 |
Presynaptic beta-adrenoceptors in rat atria: evidence for the presence of stereoselective beta 1-adrenoceptors.
Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Decerebrate State; Electric Stimulation; Epinephri | 1989 |
Adrenergic receptor subtype activation by (+)-, (-)- and (+/-)-norephedrine in the pithed rat.
Topics: Animals; Blood Pressure; Cardiovascular System; Decerebrate State; Heart Rate; Isomerism; Male; Phen | 1987 |
Equal potency of nifedipine to inhibit alpha 1-(dobutamine and BDF 6143) and alpha 2-adrenoceptor (B-HT 920) induced pressor responses in pithed rats; lack of effect of phenoxybenzamine.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Decerebrate State; Dobutamine; Dose-Re | 1987 |
Effects of the irreversible alpha-adrenoceptor antagonists phenoxybenzamine and benextramine on the effectiveness of nifedipine in inhibiting alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in pithed rats.
Topics: Animals; Azepines; Clonidine; Cystamine; Decerebrate State; Diastole; Dose-Response Relationship, Dr | 1985 |
Role of receptor reserve in the inhibition of alpha-1 adrenoceptor-mediated pressor responses by calcium antagonists in the pithed rat.
Topics: 2-Naphthylamine; Animals; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; D | 1986 |
Sensitivity of alpha-1 adrenoceptor-mediated pressor responses to inhibition by Ca++ entry blockers in the pithed rat: arguments against the role of receptor reserve.
Topics: Animals; Blood Pressure; Decerebrate State; Diastole; Male; Nifedipine; Phenoxybenzamine; Phenylephr | 1987 |
A reappraisal of the actions of noradrenaline and 5-hydroxytryptamine on cerebral cortical neurons.
Topics: Action Potentials; Adrenergic beta-Antagonists; Anesthesia; Animals; Cats; Cerebral Cortex; Creatini | 1972 |
[Alpha and beta adrenergic control of muscle tonus].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Animals, Laboratory; Catecholami | 1973 |
The influence of various pharmacological agents on the desynchronization produced by DOPA in the cerveau isolé preparation.
Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Dihydroxyphenylalanine; Disulfiram; Electroencepha | 1970 |
On the pressor action of propranolol in the rat.
Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Decerebrate State; Female; Hea | 1969 |
The EEG effects of dopa in the rabbit depending upon the level of brain-stem section.
Topics: Animals; Brain Stem; Cerebral Cortex; Cerebral Decortication; Chlorpromazine; Decerebrate State; Dih | 1974 |
Depression by reflexes of the pressor and cardiotoxic responses to ouabain.
Topics: Animals; Atropine; Blood Pressure; Buffers; Cardiovascular System; Cats; Cordotomy; Decerebrate Stat | 1969 |
An investigation of catecholamine receptors of spinal interneurones.
Topics: Action Potentials; Animals; Catecholamines; Cats; Decerebrate State; Dopamine; Drug Antagonism; Elec | 1966 |