Page last updated: 2024-11-02

phenoxybenzamine and Body Weight

phenoxybenzamine has been researched along with Body Weight in 31 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" Sixteen patients with essential hypertension were treated with guanfacine and with clonidine for 5 weeks each in a double-blind, placebo-controlled, cross-over trial."5.05Antihypertensive effect of guanfacine: a double-blind cross-over trial compared with clonidine. ( Distler, A; Kirch, W; Lüth, B, 1980)
"Sixteen patients with essential hypertension were treated with N-Amidino-2-(2,6-dichlorophenyl) acetamide hydrochloride (BS 100--141) and clonidine for five weeks each in a double-blind cross-over trial."5.04Antihypertensive effect of N-amidino-2-(2,6-dichlorophenyl) acetamide hydrochloride. A double-blind cross-over trial versus clonidine. ( Distler, A; Kirch, W, 1978)
"To determine whether the reduction in maternal placental blood flow associated with malnutrition during pregnancy results from alpha-adrenergic vasoconstriction, we measured cardiac output, uteroplacental blood flow and uteroplacental vascular resistance in ad libitum-fed and in 50% diet-restricted term-pregnant rats, using radioactive-labeled microspheres before, and again after, alpha-adrenergic receptor blockade with phenoxybenzamine."3.67Catecholamine-mediated reduction in uteroplacental blood flow in the diet-restricted, term-pregnant rat. ( Ahokas, RA; Anderson, GD; Lipshitz, J; Reynolds, SL, 1986)
" One such possibility is that N2O causes adverse reproductive toxicity secondary to its sympathomimetic effects."1.28Preventive effects of phenoxybenzamine on nitrous oxide-induced reproductive toxicity in Sprague-Dawley rats. ( Baden, JM; Fujinaga, M; Mazze, RI; Myatt, JK; Suto, A, 1991)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199027 (87.10)18.7374
1990's3 (9.68)18.2507
2000's1 (3.23)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KUROSHIMA, A1
Woodman, OL1
Missen, MA1
Boujaoude, M1
Distler, A2
Kirch, W2
Lüth, B1
Watanabe, Y1
Sokabe, H1
Watanabe, TX1
Levin, BE1
Comai, K2
Sullivan, AC2
Tsuchida, A1
Liu, Y1
Liu, GS1
Cohen, MV1
Downey, JM1
Sallés, J1
Gascón, S1
Badia, A1
Redmond, DE1
Swann, A1
Heninger, GR1
Bailey, RC1
Jackson, DM1
Kunos, G1
Swan, KG1
Kerr, JC1
Wright, CB1
Reynolds, DG1
Ohrn, PG1
Rentzhog, L1
Eisenberg, RM1
Mühlhoff, G1
Sack, H1
Schega, W1
Fujinaga, M1
Baden, JM1
Suto, A1
Myatt, JK1
Mazze, RI1
Ahokas, RA1
Reynolds, SL1
Anderson, GD1
Lipshitz, J1
Beilin, LJ1
Juel-Jensen, BE1
Willis, RJ1
Kratzing, CC1
Cicero, TJ1
Meyer, ER1
Bell, RD1
Emerson, TE1
French, SW1
Palmer, DS1
Gala, RR1
Janson, PA1
Kuo, EY1
Hyman, AI1
Haworth, G1
Bowe, ET1
Daniel, SS1
James, LS1
Kobayakawa, T1
Yelnosky, J1
Panasevich, RE1
Borrelli, AR1
Lawlor, RB1
Brenner, GM1
Stanton, HC1
Weil, JV1
Chidsey, CA1
Stout, BD1
Wiener, L1
Cox, JW1
Wagle, SR1
Ramachandran, S1

Trials

3 trials available for phenoxybenzamine and Body Weight

ArticleYear
Antihypertensive effect of guanfacine: a double-blind cross-over trial compared with clonidine.
    British journal of clinical pharmacology, 1980, Volume: 10 Suppl 1

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as To

1980
Antihypertensive effect of N-amidino-2-(2,6-dichlorophenyl) acetamide hydrochloride. A double-blind cross-over trial versus clonidine.
    International journal of clinical pharmacology and biopharmacy, 1978, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; C

1978
Alpha and beta adrenergic blockade in hypertension.
    Lancet (London, England), 1972, May-06, Volume: 1, Issue:7758

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Body Weight; Clini

1972

Other Studies

28 other studies available for phenoxybenzamine and Body Weight

ArticleYear
[EFFECT OF VASOPRESSIN ON THYROID FUNCTION].
    Nihon Naibunpi Gakkai zasshi, 1964, Feb-20, Volume: 39

    Topics: Adrenal Medulla; Adrenocorticotropic Hormone; Arginine Vasopressin; Body Weight; Cold Temperature; E

1964
Daidzein and 17 beta-estradiol enhance nitric oxide synthase activity associated with an increase in calmodulin and a decrease in caveolin-1.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:2

    Topics: Acetylcholine; Animals; Aorta; Body Weight; Calmodulin; Caveolin 1; Caveolins; Cyclic GMP; Drug Syne

2004
Combined effects of phenoxybenzamine and propranolol in hypertensive rats.
    Journal of pharmacobio-dynamics, 1980, Volume: 3, Issue:5

    Topics: Animals; Antihypertensive Agents; Body Weight; Heart Rate; Hypertension; Male; Phenoxybenzamine; Pro

1980
Metabolic and sympatho-adrenal abnormalities in the obese Zucker rat: effect of chronic phenoxybenzamine treatment.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 14, Issue:4

    Topics: Animals; Blood Glucose; Body Temperature; Body Weight; Dopamine; Eating; Epinephrine; Glycerol; Insu

1981
Effect of phenoxybenzamine on development of adipose tissue in lean and obese Zucker rats.
    The American journal of physiology, 1982, Volume: 243, Issue:5

    Topics: Adipose Tissue; Aging; Animals; Body Weight; Energy Intake; Feeding Behavior; Growth; Male; Obesity;

1982
alpha 1-adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase C.
    Circulation research, 1994, Volume: 75, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals

1994
Sustained increase in rat myocardial alpha 1A-adrenoceptors induced by 6-hydroxydopamine treatment involves a decelerated receptor turnover.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:4

    Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Body Weight; Dioxane

1996
Letter: Phenoxybenzamine in anorexia nervosa.
    Lancet (London, England), 1976, Aug-07, Volume: 2, Issue:7980

    Topics: Adult; Anorexia Nervosa; Body Weight; Female; Humans; Phenoxybenzamine; Propranolol; Satiety Respons

1976
A pharmacological study of changes in central nervous system receptor responsiveness after long-term dexamphetamine and apomorphine administration.
    Psychopharmacology, 1978, Apr-11, Volume: 56, Issue:3

    Topics: Animals; Apomorphine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Body Weight; Central Ner

1978
Thyroid hormone-dependent interconversion of myocardial alpha- and beta-adrenoceptors in the rat.
    British journal of pharmacology, 1977, Volume: 59, Issue:1

    Topics: Animals; Atrial Function; Body Weight; Calcium; Dose-Response Relationship, Drug; Heart; Heart Atria

1977
Adrenergic mechanisms in the hepatic arterial circulation of baboons.
    Surgery, 1977, Volume: 81, Issue:3

    Topics: Animals; Blood Flow Velocity; Body Weight; Epinephrine; Hepatic Artery; Homeostasis; Isoproterenol;

1977
Effect of adrenergic blockade on gastrointestinal propulsion after laparotomy. An experimental study in the rat.
    Acta chirurgica Scandinavica. Supplementum, 1976, Volume: 461

    Topics: Abdomen; Animals; Body Weight; Gastrointestinal Motility; Intestine, Small; Male; Phenoxybenzamine;

1976
Further evidence of a central alpha-adrenergic inhibitory influence on the hypothalamo-pituitary-adrenal axis in the rat.
    Neuroendocrinology, 1975, Volume: 17, Issue:2

    Topics: Adrenal Glands; Animals; Body Weight; Cerebral Ventricles; Corticosterone; Dexamethasone; Dopamine;

1975
[Pheochromocytoma].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1975, Volume: 46, Issue:5

    Topics: Adrenal Gland Neoplasms; Blood Pressure; Body Weight; Catecholamines; Headache; Humans; Neurologic M

1975
Preventive effects of phenoxybenzamine on nitrous oxide-induced reproductive toxicity in Sprague-Dawley rats.
    Teratology, 1991, Volume: 43, Issue:2

    Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Body Weight; Dose-Response Relationship,

1991
Catecholamine-mediated reduction in uteroplacental blood flow in the diet-restricted, term-pregnant rat.
    The Journal of nutrition, 1986, Volume: 116, Issue:3

    Topics: Animals; Birth Weight; Blood Pressure; Body Weight; Cardiac Output; Deficiency Diseases; Diet; Femal

1986
Pulmonary ascorbic acid loss induced by catecholamines.
    Biochemical pharmacology, 1974, Oct-01, Volume: 23, Issue:19

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Ascorbic Acid; Body Weight; Bucl

1974
Effects of phenoxybenzamine on the narcotic withdrawal syndrome in the rat.
    Neuropharmacology, 1974, Volume: 13, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Body Weight; Chlorpromazine; Depression, Che

1974
Changes of venous return and other hemodynamic parameters during bradykinin infusion.
    The American journal of physiology, 1967, Volume: 212, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Body Weight; Bradykinin; Cardiac Output; Coro

1967
Adrenergic supersensitivity during ethanol withdrawal in the rat.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2

    Topics: Animals; Body Weight; Cerebral Cortex; Cyclic AMP; Diet; Drug Hypersensitivity; Ethanol; Humans; Hyp

1973
The influence of neural blocking agents injected into the third ventricle of the rat brain and hypothalamic electrical stimulation on serum prolactin.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 140, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Atropine;

1972
Effects of sympathetic blockade on the fetal responses to asphyxia.
    Biology of the neonate, 1972, Volume: 21, Issue:1

    Topics: Animals; Asphyxia; Blood Pressure; Body Weight; Carbon Dioxide; Constriction; Electrocardiography; F

1972
[Experimental study on drugs for the treatment of myocardial infarction].
    Japanese circulation journal, 1972, Volume: 36, Issue:1

    Topics: Angiography; Animals; Benzyl Compounds; Body Weight; Carboxylic Acids; Dipyridamole; Disease Models,

1972
Pharmacology of phentermine.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 178, Issue:1

    Topics: Amphetamine; Animals; Appetite; Appetite Depressants; Blood Pressure; Body Weight; Cardiovascular Sy

1969
Adrenergic mechanism responsible for submandibular salivary glandular hypertrophy in the rat.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 173, Issue:1

    Topics: Amino Acids; Aminophylline; Anilides; Animals; Body Weight; Carbon Isotopes; Epinephrine; Female; Gu

1970
Plasma volume expansion resulting from interference with adrenergic function in normal man.
    Circulation, 1968, Volume: 37, Issue:1

    Topics: Adrenal Medulla; Adult; Blood Pressure; Blood Volume; Body Weight; Catecholamines; Cold Temperature;

1968
Combined alpha and beta sympathetic blockade in hyperthyroidism. Clinical and metabolic effects.
    Annals of internal medicine, 1969, Volume: 70, Issue:5

    Topics: Achilles Tendon; Adolescent; Adult; Aged; Body Weight; Cholesterol; Female; Humans; Hyperthyroidism;

1969
Effect of phenoxybenzamine on ketone body production in alloxan diabetic animals.
    Life sciences, 1969, May-01, Volume: 8, Issue:9

    Topics: Acetoacetates; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Hydroxybutyrate

1969