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phenoxybenzamine and Angina Pectoris

phenoxybenzamine has been researched along with Angina Pectoris in 11 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Angina Pectoris: The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" Beta-adrenergic receptor blockade with propranolol is indicated only after adequate alpha-adrenergic blockade in patients with tachycardia and catecholamine-induced arrhythmias."4.76Pharmacologic agents in the management of pheochromocytoma. ( Juan, D, 1982)
"Coronary spasm is due to strong contraction of coronary vascular smooth muscle cells which is triggered by an increase of intracellular calcium ions; hyperventilation plus TRIS-buffer infusion induces coronary spasm by decreasing hydrogen ions which antagonize the action of calcium ions."1.26Pathophysiology and treatment of coronary arterial spasm. ( Yasue, H, 1980)
"Dipyridamole was ineffective in all the cases except one in suppressing the attack."1.26Pathogenesis and treatment of angina pectoris at rest as seen from its response to various drugs. ( Akiyama, F; Kato, H; Miwa, K; Nagao, M; Omote, S; Takizawa, A; Tanaka, S; Yasue, H, 1978)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199011 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Juan, D1
Yasue, H3
Levene, DL1
Freeman, MR1
Thanavaro, S1
Krone, RJ1
Kleiger, RE1
Oliver, GC1
Omote, S1
Takizawa, A1
Nagao, M1
Miwa, K1
Kato, H2
Tanaka, S2
Akiyama, F2
Touyama, M1
Shibata, S1
Satake, N1
Kurahashi, K1
Ohtsuka, M1
Vedernikov, YP1
Judge, TG1
Nantel, A1
Freeman, J1

Reviews

3 reviews available for phenoxybenzamine and Angina Pectoris

ArticleYear
Pharmacologic agents in the management of pheochromocytoma.
    Southern medical journal, 1982, Volume: 75, Issue:2

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Angina Pectoris; Humans; Hypertension; Intrao

1982
Vasodilators..
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenergic alpha-Antagonists; Aminophylline; Angina Pectoris; Bradycardia; Bronchial Diseases; Cereb

1974
[The beta-adrenolytics].
    L'union medicale du Canada, 1968, Volume: 97, Issue:4

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Cardiovascular Diseases; Ethanolamines; Heart Diseases; Human

1968

Trials

1 trial available for phenoxybenzamine and Angina Pectoris

ArticleYear
Alpha-adrenoceptor-mediated coronary artery spasm.
    JAMA, 1976, Aug-30, Volume: 236, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Exe

1976

Other Studies

7 other studies available for phenoxybenzamine and Angina Pectoris

ArticleYear
Pathophysiology and treatment of coronary arterial spasm.
    Chest, 1980, Volume: 78, Issue:1 Suppl

    Topics: Adult; Angina Pectoris; Angina Pectoris, Variant; Atropine; Calcium; Coronary Disease; Coronary Vess

1980
Phenoxybenzamine therapy for variant angina: successful treatment of a patient with normal coronary arteries.
    Southern medical journal, 1979, Volume: 72, Issue:2

    Topics: Angina Pectoris; Angina Pectoris, Variant; Humans; Male; Middle Aged; Phenoxybenzamine

1979
Pathogenesis and treatment of angina pectoris at rest as seen from its response to various drugs.
    Japanese circulation journal, 1978, Volume: 42, Issue:1

    Topics: Aged; Angina Pectoris; Atropine; Coronary Vessels; Diltiazem; Dipyridamole; Female; Humans; Male; Mi

1978
Prinzmetal's variant form of angina as a manifestation of alpha-adrenergic receptor-mediated coronary artery spasm: documentation by coronary arteriography.
    American heart journal, 1976, Volume: 91, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Angiography; Epinephrine; Heart Rate; Humans;

1976
The vasoinhibitory action of FR 46171, a new pyridine alcohol antianginal agent, on isolated rabbit vascular smooth muscles.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:5

    Topics: Angina Pectoris; Animals; Aorta, Thoracic; beta-Cyclodextrins; Clonidine; Cyclodextrins; Dextrins; E

1988
Mechanisms of coronary spasm of isolated human epicardial coronary segments excised 3 to 5 hours after sudden death.
    Journal of the American College of Cardiology, 1986, Volume: 8, Issue:1 Suppl A

    Topics: Acetylcholine; Adult; Angina Pectoris; Calcium; Calcium Channel Blockers; Coronary Disease; Coronary

1986
Phenoxybenzamine in the treatment of cardiogenic shock.
    The Medical journal of Australia, 1969, Dec-06, Volume: 2, Issue:23

    Topics: Adult; Aged; Angina Pectoris; Catecholamines; Diabetes Complications; Female; Humans; Male; Middle A

1969