phenoxybenzamine has been researched along with Aging in 17 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of aging on the responsiveness of the isolated pacemaker of the rat to the chronotropic effect of norepinephrine, isoproterenol and soterenol were studied." | 3.68 | Subsensitivity to beta-adrenoceptor agonists in pacemakers isolated from senescent rats. ( de Moraes, S; Spadari, RC, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (64.71) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MOORE, RE | 1 |
| Zhou, LW | 1 |
| Weiss, B | 1 |
| Freilich, JS | 1 |
| Greenberg, LH | 1 |
| Nomura, Y | 1 |
| Oki, K | 1 |
| Comai, K | 1 |
| Sullivan, AC | 1 |
| Brawer, MK | 1 |
| Gurdal, H | 1 |
| Cai, G | 1 |
| Johnson, MD | 1 |
| Azuma, H | 1 |
| Tsakiris, S | 1 |
| Blair, JB | 1 |
| James, ME | 1 |
| Foster, JL | 1 |
| Linnoila, M | 1 |
| Cooper, RL | 1 |
| Iriuchijima, J | 1 |
| Numao, Y | 1 |
| Suga, H | 1 |
| Spadari, RC | 1 |
| de Moraes, S | 1 |
| Anderson-Brown, T | 1 |
| Slotkin, TA | 1 |
| Seidler, FJ | 1 |
| Caine, M | 1 |
| Claro, E | 1 |
| García, A | 1 |
| Picatoste, F | 1 |
| Takayanagi, I | 1 |
| Koike, K | 1 |
| Maeda, O | 1 |
| Ishizuka, M | 1 |
| Hruza, Z | 1 |
| Wachtlova, M | 1 |
1 review available for phenoxybenzamine and Aging
| Article | Year |
|---|---|
The role of alpha 1-blockade in benign prostatic hyperplasia.
Topics: Adrenergic alpha-Antagonists; Aging; Clinical Trials as Topic; Humans; Male; Phenoxybenzamine; Prazo | 1993 |
16 other studies available for phenoxybenzamine and Aging
| Article | Year |
|---|---|
CHEMICAL REGULATION OF HEAT PRODUCTION IN THE NEONATE.
Topics: Adrenocorticotropic Hormone; Aging; Animals, Newborn; Autonomic Agents; Biochemical Phenomena; Bioch | 1964 |
Impaired recovery of alpha 1- and alpha 2-adrenergic receptors in brain tissue of aged rats.
Topics: Aging; Animals; Brain; Brain Chemistry; Cerebral Cortex; Hypothalamus; Male; Phenoxybenzamine; Prazo | 1984 |
TRH-induced behavioral arousal in developing rats pretreated with 6-hydroxydopa.
Topics: Aging; Animals; Animals, Newborn; Catecholamines; Dihydroxyphenylalanine; Drug Interactions; Female; | 1980 |
Effect of phenoxybenzamine on development of adipose tissue in lean and obese Zucker rats.
Topics: Adipose Tissue; Aging; Animals; Body Weight; Energy Intake; Feeding Behavior; Growth; Male; Obesity; | 1982 |
Alpha 1-adrenoceptor responsiveness in the aging aorta.
Topics: Adrenergic alpha-Antagonists; Aging; Analysis of Variance; Animals; Aorta; Binding, Competitive; Clo | 1995 |
Age-related alterations in receptor density and metabolic activity in the brain.
Topics: Aging; Animals; Brain; Choline O-Acetyltransferase; Down-Regulation; Glycolysis; Male; Oxygen Consum | 1993 |
Effects of L-phenylalanine on acetylcholinesterase and Na(+), K(+)-ATPase activities in adult and aged rat brain.
Topics: Acetylcholinesterase; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals; Bra | 2001 |
Adrenergic control of glucose output and adenosine 3':5'-monophosphate levels in hepatocytes from juvenile and adult rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals; Cyclic AMP; Epinephrine; | 1979 |
Reinstatement of vaginal cycles in aged female rats.
Topics: Aging; Animals; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Drug Interactions; Estrus; | 1976 |
Effect of increasing age on hemodynamics of spontaneously hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Cardiac Output; Dextrans; Hemodynamics; Hexamethonium Compounds; Hyp | 1975 |
Subsensitivity to beta-adrenoceptor agonists in pacemakers isolated from senescent rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; Cocaine; Ethanolamines; Heart; Heart Rate; In Vitro Techni | 1991 |
Cocaine acutely inhibits DNA synthesis in developing rat brain regions: evidence for direct actions.
Topics: Aging; Animals; Brain; Cell Division; Cocaine; DNA; Female; Leucine; Lidocaine; Methoxamine; Nerve T | 1990 |
Medical management of prostatic hyperplasia.
Topics: Adrenergic alpha-Antagonists; Aged; Aging; Bromocriptine; Cyproterone; Humans; Male; Phenoxybenzamin | 1986 |
Histamine-stimulated phosphoinositide hydrolysis in developing rat brain.
Topics: Aging; Animals; Cerebral Cortex; Histamine; Histamine Antagonists; Hydrolysis; Phenoxybenzamine; Pho | 1987 |
A difference in alpha-adrenoceptor mechanisms in vasa deferentia isolated from young and old rats.
Topics: Aging; Animals; In Vitro Techniques; Male; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Rats, I | 1986 |
Diminution of bone blood flow and capillary network in rats during aging.
Topics: Aging; Animals; Bone and Bones; Calcium Isotopes; Capillaries; Female; Haversian System; Hydroxyprol | 1969 |