Page last updated: 2024-11-02

phenoxybenzamine and Action Tremor

phenoxybenzamine has been researched along with Action Tremor in 12 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Research Excerpts

ExcerptRelevanceReference
"Phenoxybenzamine (5 mg/kg IP) and trazodone (5 mg/kg IP) reduced tremors produced in mice by administration of oxotremorine (10 mg/kg), harmaline (80 mg/kg), catechol (60 mg/kg), kepone (200 mg/kg) and clonidine (100 mg/kg)."7.66Serotonin-norepinephrine interactions in the tremorolytic actions of phenoxybenzamine and trazodone. ( Hwang, EC; van Woert, MH, 1979)
" In rats the effect of drugs on oxotremorine tremor and oxotremorine-induced increase in brain acetylcholine has been investigated."7.65Effects of drugs on tremor and increase in brain acetylcholine produced by oxotremorine in the rat. ( Cox, B; Potkonjak, D, 1970)
"Tremor was quantified 8 hr later by spectral analysis of whole body movements."5.27Modulation of p,p'-DDT-induced tremor by catecholaminergic agents. ( Herr, DW; Tilson, HA, 1987)
"Phenoxybenzamine (5 mg/kg IP) and trazodone (5 mg/kg IP) reduced tremors produced in mice by administration of oxotremorine (10 mg/kg), harmaline (80 mg/kg), catechol (60 mg/kg), kepone (200 mg/kg) and clonidine (100 mg/kg)."3.66Serotonin-norepinephrine interactions in the tremorolytic actions of phenoxybenzamine and trazodone. ( Hwang, EC; van Woert, MH, 1979)
" In rats the effect of drugs on oxotremorine tremor and oxotremorine-induced increase in brain acetylcholine has been investigated."3.65Effects of drugs on tremor and increase in brain acetylcholine produced by oxotremorine in the rat. ( Cox, B; Potkonjak, D, 1970)
"Tremor was quantified 8 hr later by spectral analysis of whole body movements."1.27Modulation of p,p'-DDT-induced tremor by catecholaminergic agents. ( Herr, DW; Tilson, HA, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199012 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ROOS, BE1
STEG, G1
Foley, TH2
Marsden, CD2
Owen, DA2
McAllister, RG1
Silvestrini, B1
Lisciani, R1
Hwang, EC1
van Woert, MH1
Kulkarni, SK1
Kaul, PN1
Banna, NR1
Kurkjian, R1
Herr, DW1
Tilson, HA1
Koller, WC1
Vaupel, DB1
Martin, WR1
Cox, B2
Potkonjak, D2

Trials

1 trial available for phenoxybenzamine and Action Tremor

ArticleYear
Peripheral beta-adrenergic receptors concerned with tremor.
    Clinical science, 1967, Volume: 33, Issue:1

    Topics: Adult; Arteries; Blood Circulation; Bradykinin; Catecholamines; Epinephrine; Fingers; Forearm; Human

1967

Other Studies

11 other studies available for phenoxybenzamine and Action Tremor

ArticleYear
THE EFFECT OF L-3, 4-DIHYDROXYPHENYLALANINE AND DL-5-HYDROXYTRYPTOPHAN ON RIGIDITY AND TREMOR INDUCED BY RESERPINE, CHLORPROMAZINE AND PHENOXYBENZAMINE.
    Life sciences (1962), 1964, Volume: 3

    Topics: 5-Hydroxytryptophan; Amino Acids; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Inulin; Movement

1964
Evidence for a direct peripheral effect of adrenaline on physiological tremor in man.
    The Journal of physiology, 1967, Volume: 189, Issue:2

    Topics: Epinephrine; Fingers; Forearm; Humans; Isoproterenol; Peripheral Nerves; Phenoxybenzamine; Propranol

1967
Experimental data suggesting an adrenergic mechanism in the production of parkinsonian symptoms.
    Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Clonidine; Female; Fenclonine; Imipramine; Male; Mice; Mice,

1976
Serotonin-norepinephrine interactions in the tremorolytic actions of phenoxybenzamine and trazodone.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Male; Mice; Norepinephrine; Phenoxybenzamine; Piperazines; Serotonin;

1979
Modification by levo-propranolol of tremors induced by harmine in mice.
    Experientia, 1979, Dec-15, Volume: 35, Issue:12

    Topics: Animals; Cyproheptadine; Dose-Response Relationship, Drug; Harmine; Male; Mice; Phenoxybenzamine; Pr

1979
A novel tremorigen antagonized by D-amphetamine.
    Brain research, 1975, Apr-04, Volume: 87, Issue:1

    Topics: Acetates; Aldehydes; Amines; Animals; Atropine; Calcium; Chlorpromazine; Dextroamphetamine; Diazepam

1975
Modulation of p,p'-DDT-induced tremor by catecholaminergic agents.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:2

    Topics: Animals; Apomorphine; Clonidine; DDT; Dopamine; Haloperidol; Male; Norepinephrine; Phenoxybenzamine;

1987
Ineffectiveness of phenoxybenzamine in essential tremor.
    Journal of neurology, neurosurgery, and psychiatry, 1986, Volume: 49, Issue:2

    Topics: Dose-Response Relationship, Drug; Humans; Middle Aged; Phenoxybenzamine; Tremor

1986
Interaction of oxotremorine with atropine, chlorpromazine, cyproheptadine, imipramine and phenoxybenzamine on the flexor reflex of the chronic spinal dog.
    Psychopharmacologia, 1973, Volume: 30, Issue:1

    Topics: Animals; Atropine; Chlorpromazine; Cyproheptadine; Dogs; Drug Interactions; Imipramine; Oxotremorine

1973
An investigation of the tremorgenic actions of harmine in the rat.
    European journal of pharmacology, 1971, Volume: 16, Issue:1

    Topics: Acetylcholine; Alkaloids; Animals; Atropine; Brain Chemistry; Carbamates; Guinea Pigs; In Vitro Tech

1971
Effects of drugs on tremor and increase in brain acetylcholine produced by oxotremorine in the rat.
    British journal of pharmacology, 1970, Volume: 38, Issue:1

    Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Male; Phenoxybenzamine; Phenylalanine; Propranolol;

1970