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phenolsulfonphthalein and Diabetic Nephropathies

phenolsulfonphthalein has been researched along with Diabetic Nephropathies in 1 studies

Phenolsulfonphthalein: Red dye, pH indicator, and diagnostic aid for determination of renal function. It is used also for studies of the gastrointestinal and other systems.
phenol red : 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney.

Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.

Research Excerpts

ExcerptRelevanceReference
"17) in urine by a reliable radioimmunoassay can provide a suitable index of renal tubular function and how lysozymuria develops in temporal relation to proteinuria in diabetic nephropathy, we have compared the urinary excretion of lysozyme and beta 2-microglobulin with the 15-min excretion rate of phenolsulfonphthalein in 39 patients with Type 2 (non-insulin-dependent) diabetes and investigated the temporal relation between the onset of lysozymuria and proteinuria in 15 patients with Type 1 (insulin-dependent) diabetes."3.67Determination of urinary lysozyme for potential detection of tubular dysfunction in diabetic nephropathy. ( Fukuda, M; Hirota, M; Shima, K; Tanaka, A, 1986)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shima, K1
Hirota, M1
Fukuda, M1
Tanaka, A1

Other Studies

1 other study available for phenolsulfonphthalein and Diabetic Nephropathies

ArticleYear
Determination of urinary lysozyme for potential detection of tubular dysfunction in diabetic nephropathy.
    Clinical chemistry, 1986, Volume: 32, Issue:10

    Topics: Adolescent; Adult; Aged; beta 2-Microglobulin; Child; Child, Preschool; Diabetes Mellitus, Type 1; D

1986