Page last updated: 2024-11-02

phenolsulfonphthalein and Alzheimer Disease

phenolsulfonphthalein has been researched along with Alzheimer Disease in 3 studies

Phenolsulfonphthalein: Red dye, pH indicator, and diagnostic aid for determination of renal function. It is used also for studies of the gastrointestinal and other systems.
phenol red : 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Necula, M1
Kayed, R1
Milton, S1
Glabe, CG1
Erdogan, M1
Kilic, B1
Sagkan, RI1
Aksakal, F1
Ercetin, T1
Gulcan, HO1
Dogruer, DS1
Liu, D1
Zhang, H1
Wang, Y1
Liu, W1
Yin, G1
Wang, D1
Li, J1
Shi, T1
Wang, Z1

Other Studies

3 other studies available for phenolsulfonphthalein and Alzheimer Disease

ArticleYear
Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct.
    The Journal of biological chemistry, 2007, Apr-06, Volume: 282, Issue:14

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Humans; Plaque, Amyloid; Protein Structu

2007
Design, synthesis and biological evaluation of new benzoxazolone/benzothiazolone derivatives as multi-target agents against Alzheimer's disease.
    European journal of medicinal chemistry, 2021, Feb-15, Volume: 212

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, N

2021
Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2022, Feb-05, Volume: 229

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Binding Sites; Blood-Brain

2022