Page last updated: 2024-11-02

phenolphthalein and Hemangiosarcoma

phenolphthalein has been researched along with Hemangiosarcoma in 1 studies

Phenolphthalein: An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.

Hemangiosarcoma: A rare malignant neoplasm characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and lining irregular blood-filled or lumpy spaces. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Phenolphthalein has carcinogenic activity, causing malignant lymphomas in B6C3F1 mice at a dietary dose of 3000 ppm in a 2-year carcinogenicity study and in heterozygous p53-deficient female mice at the same dose in a 6-month study."3.70Lack of susceptibility of transgenic mice carrying the human c-Ha-ras proto-oncogene (rasH2 mice) to phenolphthalein in a 6-month carcinogenicity study. ( Hirose, M; Koujitani, T; Mitsumori, K; Nomura, T; Onodera, H; Takagi, H; Usui, T; Yasuhara, K, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koujitani, T1
Yasuhara, K1
Usui, T1
Nomura, T1
Onodera, H1
Takagi, H1
Hirose, M1
Mitsumori, K1

Other Studies

1 other study available for phenolphthalein and Hemangiosarcoma

ArticleYear
Lack of susceptibility of transgenic mice carrying the human c-Ha-ras proto-oncogene (rasH2 mice) to phenolphthalein in a 6-month carcinogenicity study.
    Cancer letters, 2000, May-01, Volume: 152, Issue:2

    Topics: Adenoma, Liver Cell; Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Female; Genes, ras; H

2000