phenolphthalein has been researched along with Hemangiosarcoma in 1 studies
Phenolphthalein: An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.
Hemangiosarcoma: A rare malignant neoplasm characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and lining irregular blood-filled or lumpy spaces. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenolphthalein has carcinogenic activity, causing malignant lymphomas in B6C3F1 mice at a dietary dose of 3000 ppm in a 2-year carcinogenicity study and in heterozygous p53-deficient female mice at the same dose in a 6-month study." | 3.70 | Lack of susceptibility of transgenic mice carrying the human c-Ha-ras proto-oncogene (rasH2 mice) to phenolphthalein in a 6-month carcinogenicity study. ( Hirose, M; Koujitani, T; Mitsumori, K; Nomura, T; Onodera, H; Takagi, H; Usui, T; Yasuhara, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koujitani, T | 1 |
| Yasuhara, K | 1 |
| Usui, T | 1 |
| Nomura, T | 1 |
| Onodera, H | 1 |
| Takagi, H | 1 |
| Hirose, M | 1 |
| Mitsumori, K | 1 |
1 other study available for phenolphthalein and Hemangiosarcoma
| Article | Year |
|---|---|
Lack of susceptibility of transgenic mice carrying the human c-Ha-ras proto-oncogene (rasH2 mice) to phenolphthalein in a 6-month carcinogenicity study.
Topics: Adenoma, Liver Cell; Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Female; Genes, ras; H | 2000 |