phenolphthalein has been researched along with Chromosome-Defective Micronuclei in 2 studies
Phenolphthalein: An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bisacodyl was negative in the SHE assay." | 1.33 | Phenolphthalein and bisacodyl: assessment of genotoxic and carcinogenic responses in heterozygous p53 (+/-) mice and syrian hamster embryo (SHE) assay. ( Blanchard, KT; Furst, S; Lilly, PD; Majeska, JB; Mennear, JH; Stoll, RE; Stoltz, JH, 2006) |
| "Phenolphthalein was administered in the diet at 200, 375, 750, 3,000, and 12,000 ppm (corresponding to a time-weighted average of 37, 71, 146, 569, and 2,074 mg/kg/day, respectively) for 6 months (183 days)." | 1.30 | Measurement of micronucleated erythrocytes and DNA damage during chronic ingestion of phenolphthalein in transgenic female mice heterozygous for the p53 gene. ( Dunnick, JK; Furedi-Machacek, M; Satterfield, D; Tice, RR; Udumudi, A; Vasquez, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stoll, RE | 1 |
| Blanchard, KT | 1 |
| Stoltz, JH | 1 |
| Majeska, JB | 1 |
| Furst, S | 1 |
| Lilly, PD | 1 |
| Mennear, JH | 1 |
| Tice, RR | 1 |
| Furedi-Machacek, M | 1 |
| Satterfield, D | 1 |
| Udumudi, A | 1 |
| Vasquez, M | 1 |
| Dunnick, JK | 1 |
2 other studies available for phenolphthalein and Chromosome-Defective Micronuclei
| Article | Year |
|---|---|
Phenolphthalein and bisacodyl: assessment of genotoxic and carcinogenic responses in heterozygous p53 (+/-) mice and syrian hamster embryo (SHE) assay.
Topics: Animals; Bisacodyl; Carcinogens; Cathartics; Cell Transformation, Neoplastic; Cells, Cultured; Crice | 2006 |
Measurement of micronucleated erythrocytes and DNA damage during chronic ingestion of phenolphthalein in transgenic female mice heterozygous for the p53 gene.
Topics: Administration, Oral; Animals; Cathartics; Diet; DNA; DNA Damage; Erythrocytes, Abnormal; Female; Ge | 1998 |