phenolphthalein has been researched along with Cell Transformation, Neoplastic in 2 studies
Phenolphthalein: An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bisacodyl was negative in the SHE assay." | 1.33 | Phenolphthalein and bisacodyl: assessment of genotoxic and carcinogenic responses in heterozygous p53 (+/-) mice and syrian hamster embryo (SHE) assay. ( Blanchard, KT; Furst, S; Lilly, PD; Majeska, JB; Mennear, JH; Stoll, RE; Stoltz, JH, 2006) |
| "Treatment with phenolphthalein for 48 hr induced a dose-dependent increase in morphological transformation of SHE cells." | 1.30 | Cell-transforming activity and genotoxicity of phenolphthalein in cultured Syrian hamster embryo cells. ( Barrett, JC; Hamaguchi, F; Hasegawa, K; Someya, T; Tamura, Y; Tanaka, Y; Tsutsui, T; Uehama, A; Yagi, E; Yamamoto, H, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stoll, RE | 1 |
| Blanchard, KT | 1 |
| Stoltz, JH | 1 |
| Majeska, JB | 1 |
| Furst, S | 1 |
| Lilly, PD | 1 |
| Mennear, JH | 1 |
| Tsutsui, T | 1 |
| Tamura, Y | 1 |
| Yagi, E | 1 |
| Hasegawa, K | 1 |
| Tanaka, Y | 1 |
| Uehama, A | 1 |
| Someya, T | 1 |
| Hamaguchi, F | 1 |
| Yamamoto, H | 1 |
| Barrett, JC | 1 |
2 other studies available for phenolphthalein and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Phenolphthalein and bisacodyl: assessment of genotoxic and carcinogenic responses in heterozygous p53 (+/-) mice and syrian hamster embryo (SHE) assay.
Topics: Animals; Bisacodyl; Carcinogens; Cathartics; Cell Transformation, Neoplastic; Cells, Cultured; Crice | 2006 |
Cell-transforming activity and genotoxicity of phenolphthalein in cultured Syrian hamster embryo cells.
Topics: Animals; Cathartics; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Abe | 1997 |