phenolphthalein has been researched along with Body Weight in 7 studies
Phenolphthalein: An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenolphthalein has carcinogenic activity, causing malignant lymphomas in B6C3F1 mice at a dietary dose of 3000 ppm in a 2-year carcinogenicity study and in heterozygous p53-deficient female mice at the same dose in a 6-month study." | 3.70 | Lack of susceptibility of transgenic mice carrying the human c-Ha-ras proto-oncogene (rasH2 mice) to phenolphthalein in a 6-month carcinogenicity study. ( Hirose, M; Koujitani, T; Mitsumori, K; Nomura, T; Onodera, H; Takagi, H; Usui, T; Yasuhara, K, 2000) |
| " with a dose of 15 mg/kg body weight of phenolphthalein." | 3.67 | The disaccharide effect of sucrose feeding on glucuronide excretion and bile concentration of injected phenolphthalein in guinea pigs. ( Ahrens, RA; Garland, SL; Kigutha, HN; Russek, E, 1985) |
| "Phenolphthalein has been shown to have estrogenic and clastogenic properties." | 1.29 | Phenolphthalein exposure causes multiple carcinogenic effects in experimental model systems. ( Dunnick, JK; Hailey, JR, 1996) |
| "Phenolphthalein is a cathartic agent that is widely used in over-the-counter laxatives." | 1.28 | Subchronic (13-week) toxicity studies of oral phenolphthalein in Fischer 344 rats and B6C3F1 mice. ( Chapin, RE; Dietz, DD; Elwell, MR; Filler, R; Shelby, MD; Stedham, MA; Thompson, MB, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dunnick, JK | 1 |
| Hailey, JR | 1 |
| Wenzl, HH | 1 |
| Fine, KD | 1 |
| Santa Ana, CA | 1 |
| Porter, JL | 1 |
| Fordtran, JS | 1 |
| Koujitani, T | 1 |
| Yasuhara, K | 1 |
| Usui, T | 1 |
| Nomura, T | 1 |
| Onodera, H | 1 |
| Takagi, H | 1 |
| Hirose, M | 1 |
| Mitsumori, K | 1 |
| Dietz, DD | 1 |
| Elwell, MR | 1 |
| Chapin, RE | 1 |
| Shelby, MD | 1 |
| Thompson, MB | 1 |
| Filler, R | 1 |
| Stedham, MA | 1 |
| Watanabe, HK | 1 |
| Hoskins, B | 1 |
| Ho, IK | 1 |
| Ahrens, RA | 1 |
| Garland, SL | 1 |
| Kigutha, HN | 1 |
| Russek, E | 1 |
1 trial available for phenolphthalein and Body Weight
| Article | Year |
|---|---|
Effect of fludrocortisone and spironolactone on sodium and potassium losses in secretory diarrhea.
Topics: Adult; Aldosterone; Body Weight; Cathartics; Diarrhea; Electrolytes; Feces; Female; Fludrocortisone; | 1997 |
6 other studies available for phenolphthalein and Body Weight
| Article | Year |
|---|---|
Phenolphthalein exposure causes multiple carcinogenic effects in experimental model systems.
Topics: Animals; Body Weight; Cathartics; Female; Hematopoietic System; Kidney Neoplasms; Male; Mice; Neopla | 1996 |
Reproductive toxicology. Phenolphthalein.
Topics: Animals; Birth Weight; Body Weight; Cathartics; Dose-Response Relationship, Drug; Epididymis; Female | 1997 |
Lack of susceptibility of transgenic mice carrying the human c-Ha-ras proto-oncogene (rasH2 mice) to phenolphthalein in a 6-month carcinogenicity study.
Topics: Adenoma, Liver Cell; Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Female; Genes, ras; H | 2000 |
Subchronic (13-week) toxicity studies of oral phenolphthalein in Fischer 344 rats and B6C3F1 mice.
Topics: Animals; Bile Acids and Salts; Biological Availability; Body Weight; Bone Marrow; Eating; Female; Ma | 1992 |
Effects of subacute treatment with cocaine on activities of N-demethylase, UDP-glucuronyltransferase and sulfotransferase in WKY and SHR rat liver--sex and strain differences.
Topics: Animals; Body Weight; Cocaine; Female; Glucuronosyltransferase; Hypertension; Liver; Male; Nitrophen | 1988 |
The disaccharide effect of sucrose feeding on glucuronide excretion and bile concentration of injected phenolphthalein in guinea pigs.
Topics: Animals; Bile; Body Weight; Dietary Carbohydrates; Diuresis; Fructose; Glucose; Glucuronates; Guinea | 1985 |