phenolphthalein has been researched along with Abnormalities, Autosome in 4 studies
Phenolphthalein: An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenolphthalein is a nonprescription laxative agent that has been widely used during this century." | 1.31 | Phenolphthalein induces chromosome aberrations in human and Chinese hamster liver cells (CHEL) cultured in vitro. ( Amoruso, S; Andreozzi, L; Biondi, O; Motta, S, 2000) |
| "Phenolphthalein did not produce DNA strand breaks in rat hepatocytes or DNA adducts in Chinese hamster ovary (CHO) cells." | 1.31 | Induction of chromosome aberrations in vitro by phenolphthalein: mechanistic studies. ( Armstrong, MJ; Galloway, SM; Gara, JP; Gealy, R; Greenwood, SK; Hilliard, CA; Laws, GM, 2000) |
| "Treatment with phenolphthalein for 48 hr induced a dose-dependent increase in morphological transformation of SHE cells." | 1.30 | Cell-transforming activity and genotoxicity of phenolphthalein in cultured Syrian hamster embryo cells. ( Barrett, JC; Hamaguchi, F; Hasegawa, K; Someya, T; Tamura, Y; Tanaka, Y; Tsutsui, T; Uehama, A; Yagi, E; Yamamoto, H, 1997) |
| "Phenolphthalein was tested for the induction of micronucleated erythrocytes in mice." | 1.29 | Phenolphthalein: induction of micronucleated erythrocytes in mice. ( Gulati, DK; Kaur, P; Shelby, MD; Witt, KL, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Witt, KL | 1 |
| Gulati, DK | 1 |
| Kaur, P | 1 |
| Shelby, MD | 1 |
| Tsutsui, T | 1 |
| Tamura, Y | 1 |
| Yagi, E | 1 |
| Hasegawa, K | 1 |
| Tanaka, Y | 1 |
| Uehama, A | 1 |
| Someya, T | 1 |
| Hamaguchi, F | 1 |
| Yamamoto, H | 1 |
| Barrett, JC | 1 |
| Biondi, O | 1 |
| Andreozzi, L | 1 |
| Amoruso, S | 1 |
| Motta, S | 1 |
| Armstrong, MJ | 1 |
| Gara, JP | 1 |
| Gealy, R | 1 |
| Greenwood, SK | 1 |
| Hilliard, CA | 1 |
| Laws, GM | 1 |
| Galloway, SM | 1 |
4 other studies available for phenolphthalein and Abnormalities, Autosome
| Article | Year |
|---|---|
Phenolphthalein: induction of micronucleated erythrocytes in mice.
Topics: Animals; CHO Cells; Chromosome Aberrations; Cricetinae; Dose-Response Relationship, Drug; Erythrocyt | 1995 |
Cell-transforming activity and genotoxicity of phenolphthalein in cultured Syrian hamster embryo cells.
Topics: Animals; Cathartics; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Abe | 1997 |
Phenolphthalein induces chromosome aberrations in human and Chinese hamster liver cells (CHEL) cultured in vitro.
Topics: Amniotic Fluid; Animals; Cathartics; Cell Line; Cells, Cultured; CHO Cells; Chromosome Aberrations; | 2000 |
Induction of chromosome aberrations in vitro by phenolphthalein: mechanistic studies.
Topics: Animals; Antioxidants; Cathartics; Cell Line; Chelating Agents; CHO Cells; Chromosome Aberrations; C | 2000 |