phenol and Pain, Intractable studies

Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.

Research Excerpts

Excerpt	Relevance	Reference
"We examined the efficacy of percutaneous cervical cordotomy (PCC) and subarachnoid phenol block using fluoroscopy (SAPB-F) for control of chest and/or back pain from costopleural syndrome."	9.07	Percutaneous cervical cordotomy and subarachnoid phenol block using fluoroscopy in pain control of costopleural syndrome. ( Amakawa, K; Arai, T; Kimura, S; Nagaro, T; Tabo, E; Yamauchi, Y, 1994)
"We examined the efficacy of percutaneous cervical cordotomy (PCC) and subarachnoid phenol block using fluoroscopy (SAPB-F) for control of chest and/or back pain from costopleural syndrome."	5.07	Percutaneous cervical cordotomy and subarachnoid phenol block using fluoroscopy in pain control of costopleural syndrome. ( Amakawa, K; Arai, T; Kimura, S; Nagaro, T; Tabo, E; Yamauchi, Y, 1994)
"The medical records of 11 patients with recurrent unresectable adenocarcinoma of the rectum who had intrathecal phenol block for the management of intractable pain were reviewed."	3.68	Intrathecal phenol rhizotomy for management of pain in recurrent unresectable carcinoma of the rectum. ( Herrera, L; Petrelli, NJ; Rodriguez-Bigas, M; West, C, 1991)
"Patients with advanced cancer may present complex sets of symptoms, of which pain is the most prevalent."	2.42	[Neurolytic blocks for cancer pain--still a useful therapeutic strategy]. ( Bjørgo, S; Hauser, M; Kongsgaard, UE, 2004)
"He complained of refractory pain in the lower back and lower extremities despite high-dose opioid treatment based on the WHO ladder."	1.37	Intrathecal neurolytic block in a patient with refractory cancer pain. ( Watanabe, A; Yamakage, M, 2011)
"Lidocaine was then injected followed by injection of 7% phenol for performing CLS."	1.35	[Analgesic effects of chemical lumbar sympathectomy on refractory pain in the lower limbs]. ( Hu, SJ; Peng, KR; Yang, HJ, 2008)
"Four cases of cancer patients whose intractable pain was treated by the authors using intrathecal neurolysis are presented."	1.32	Intrathecal neurolytic blocks for the relief of cancer pain. ( Candido, K; Stevens, RA, 2003)
"Fifteen patients with cancer pain (average age of 61 years) were treated with serial epidural phenol in glycerin injections."	1.28	Mapping the spread of epidural phenol in cancer pain patients by radionuclide admixture and epidural scintigraphy. ( Finch, PM; Lovegrove, FT; Salmon, JB; Warwick, A, 1992)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (46.88)	18.7374
1990's	6 (18.75)	18.2507
2000's	4 (12.50)	29.6817
2010's	6 (18.75)	24.3611
2020's	1 (3.13)	2.80

Authors	Studies
Mach, S	1
Collie, MA	1
Pesce, MB	1
Loo, NH	1
Matchett, G	2
Restrepo-Garces, CE	1
Saldarriaga, NE	1
Jaramillo, S	1
Gomez, CM	1
Vargas, JF	1
Ramirez, LJ	1
Yin, C	1
Yang, HJ	1
Peng, KR	1
Hu, SJ	1
Watanabe, A	1
Yamakage, M	1
Kambadakone, A	1
Thabet, A	1
Gervais, DA	1
Mueller, PR	1
Arellano, RS	1
Arakawa, Y	1
Inoue, D	1
Sakuyama, T	1
Nagasaki, E	1
Aiba, K	1
Shimazaki, M	1
Egawa, H	1
Motojima, F	1
Fujimaki, K	1
Hamaguchi, S	1
Okuda, Y	1
Kitajima, T	1
NATHAN, PW	2
SCOTT, TG	1
BROWN, AS	1
JERVELL, J	1
GORDON, RA	1
GOEL, SB	1
TANK, TM	1
DOHN, DF	1
GARDNER, WJ	1
STOVNER, J	1
ENDRESEN, R	1
Candido, K	1
Stevens, RA	1
Kongsgaard, UE	1
Bjørgo, S	1
Hauser, M	1
Valley, MA	1
Raja, SN	1
Robertson, DH	1
Gerbershagen, HU	1
Racz, GB	1
Sabonghy, M	1
Gintautas, J	1
Kline, WM	1
Wilkening, M	1
Lassaunière, JM	1
Freysz, M	1
Foissac, JC	1
Weiller, J	1
Roulet, JJ	1
Honnart, D	1
Tammelleo, AD	1
Nagaro, T	1
Amakawa, K	1
Yamauchi, Y	1
Tabo, E	1
Kimura, S	1
Arai, T	1
Antila, H	1
Kirvelä, O	1
Salmon, JB	1
Finch, PM	1
Lovegrove, FT	1
Warwick, A	1
Rodriguez-Bigas, M	1
Petrelli, NJ	1
Herrera, L	1
West, C	1
Kuś, M	2
Dobrogowski, J	2
Beliaev, DG	1
Frid, IA	1
Genin, IB	1
Coombs, DW	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Prospective, Randomized, Double-Blinded, Allocation Concealed Study Comparing the Efficacy of Liposomal Bupivacaine Over Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Primary Total Knee Arthro[NCT02624856]	Phase 4	0 participants (Actual)	Interventional	2015-11-30	Withdrawn (stopped due to Lack of funding)
Efficacy and Safety of Paragastric Neural Block in Controlling Pain, Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy; Prospective Randomized Controlled Double-blind Study[NCT05984160]		90 participants (Actual)	Interventional	2023-05-09	Active, not recruiting
Celiac Plexus Radiosurgery for Pain Management in Advanced Cancer Patients - a Phase II Trial[NCT02356406]	Phase 2	52 participants (Anticipated)	Interventional	2014-01-31	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
CT-guided celiac plexus neurolysis: a review of anatomy, indications, technique, and tips for successful treatment. Radiographics : a review publication of the Radiological Society of North America, Inc, 2011, Volume: 31, Issue:6 Topics: Abdominal Neoplasms; Abdominal Pain; Autonomic Nerve Block; Celiac Plexus; Contraindications; Ethano	2011
CT-guided celiac plexus neurolysis: a review of anatomy, indications, technique, and tips for successful treatment. Radiographics : a review publication of the Radiological Society of North America, Inc, 2011, Volume: 31, Issue:6 Topics: Abdominal Neoplasms; Abdominal Pain; Autonomic Nerve Block; Celiac Plexus; Contraindications; Ethano	2011
CT-guided celiac plexus neurolysis: a review of anatomy, indications, technique, and tips for successful treatment. Radiographics : a review publication of the Radiological Society of North America, Inc, 2011, Volume: 31, Issue:6 Topics: Abdominal Neoplasms; Abdominal Pain; Autonomic Nerve Block; Celiac Plexus; Contraindications; Ethano	2011
CT-guided celiac plexus neurolysis: a review of anatomy, indications, technique, and tips for successful treatment. Radiographics : a review publication of the Radiological Society of North America, Inc, 2011, Volume: 31, Issue:6 Topics: Abdominal Neoplasms; Abdominal Pain; Autonomic Nerve Block; Celiac Plexus; Contraindications; Ethano	2011
[Neurolytic blocks for cancer pain--still a useful therapeutic strategy]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2004, Feb-19, Volume: 124, Issue:4 Topics: Central Nervous System Depressants; Ethanol; Humans; Neoplasms; Nerve Block; Pain, Intractable; Phen	2004
[Chemical neurolysis in advanced neoplasms]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1985, Feb-11, Volume: 40, Issue:6 Topics: Anesthesia, Epidural; Humans; Neoplasms; Nerve Block; Pain, Intractable; Palliative Care; Phenol; Ph	1985

Article	Year
Palliative Nerve Block for Penile Calciphylaxis: A Case Report on Ultrasound-Guided Phenol Neurolysis. A&A practice, 2021, Mar-08, Volume: 15, Issue:3 Topics: Aged; Calciphylaxis; Humans; Male; Nerve Block; Pain, Intractable; Penis; Phenol; Ultrasonography, I	2021
Use of a Tilting Orthopedic Fracture Table to Facilitate Proper Patient Positioning During Intrathecal Neurolysis With Hyperbaric Phenol: A Case Report. A & A case reports, 2017, Sep-15, Volume: 9, Issue:6 Topics: Adult; Anesthesia, Spinal; Female; Humans; Neoplasm Metastasis; Nerve Block; Pain, Intractable; Pati	2017
Ganglion impar phenol injection in a pediatric patient with refractory cancer pain. Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:2 Topics: Child, Preschool; Ganglia, Sympathetic; Humans; Male; Nerve Block; Pain Measurement; Pain, Intractab	2014
Intercostal administration of liposomal bupivacaine as a prognostic nerve block prior to phenol neurolysis for intractable chest wall pain. Journal of pain & palliative care pharmacotherapy, 2014, Volume: 28, Issue:1 Topics: Anesthetics, Local; Bupivacaine; Female; Humans; Liposomes; Middle Aged; Nerve Block; Pain, Intracta	2014
[Analgesic effects of chemical lumbar sympathectomy on refractory pain in the lower limbs]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2008, Volume: 28, Issue:11 Topics: Aged; Aged, 80 and over; Analgesia; Female; Humans; Lidocaine; Lower Extremity; Male; Middle Aged; P	2008
Intrathecal neurolytic block in a patient with refractory cancer pain. Journal of anesthesia, 2011, Volume: 25, Issue:4 Topics: Analgesics, Opioid; Glycerol; Humans; Injections, Spinal; Ketamine; Male; Middle Aged; Morphine; Ner	2011
[Strontium-89 therapy and subarachnoid phenol block successfully eliminated intractable pain of metastasis in the patient with advanced urachal carcinoma]. Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38 Suppl 1 Topics: Adult; Bone Neoplasms; Humans; Magnetic Resonance Imaging; Male; Pain, Intractable; Phenol; Strontiu	2011
[Intrathecal phenol block in a child with cancer pain--a case report]. Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:7 Topics: Adolescent; Analgesics, Opioid; Anesthesia, Spinal; Bone Neoplasms; Humans; Injections, Intravenous;	2003
Intrathecal phenol for intractable pain: safety and dangers of the method. Lancet (London, England), 1958, Jan-11, Volume: 1, Issue:7011 Topics: Humans; Pain, Intractable; Phenol; Phenols; Safety	1958
Treatment of intractable pain by subarachnoid injection of carbolic acid. Lancet (London, England), 1958, Nov-08, Volume: 2, Issue:7054 Topics: Anesthesia; Anesthesia, Conduction; Humans; Injections; Pain Management; Pain, Intractable; Phenol;	1958
[Intrathecal phenol with intractable pain and spastic conditions. A review with a report on 6 cases]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1961, Aug-01, Volume: 81 Topics: Aged; Humans; Muscle Spasticity; Ozone; Pain, Intractable; Paralysis; Phenol; Phenols	1961
Intrathecal phenol block in treatment of intractable pain of malignant disease. Canadian Anaesthetists' Society journal, 1963, Volume: 10 Topics: Anesthesia, Spinal; Humans; Hypothermia, Induced; Neoplasms; Pain; Pain, Intractable; Phenol; Phenol	1963
INTRATHECAL INJECTIONS OF ALCOHOL OR PHENOL FOR RELIEF OF INTRACTABLE PAIN. Cleveland Clinic quarterly, 1963, Volume: 30 Topics: Alcohols; Analgesia; Ethanol; Humans; Injections, Spinal; Pain; Pain Management; Pain, Intractable;	1963
[INTRATHECAL PHENOL FOR INTRACTABLE CANCER PAIN]. Nordisk medicin, 1964, Aug-06, Volume: 72 Topics: Humans; Injections; Injections, Spinal; Neoplasms; Pain; Pain, Intractable; Palliative Care; Pharmac	1964
TREATMENT OF INTRACTABLE PAIN BY CHEMICAL RHIZOTOMY WITH PHENOL SOLUTIONS. Current medicine and drugs, 1965, Volume: 5, Issue:8 Topics: Drug Therapy; Humans; Pain; Pain, Intractable; Phenol; Phenols; Rhizotomy; Spinal Nerves	1965
Intrathecal neurolytic blocks for the relief of cancer pain. Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:3 Topics: Aged; Anesthetics, Local; Clinical Trials as Topic; Ethanol; Female; Humans; Injections, Spinal; Mal	2003
Relief of intractable pain from metastatic multiple myeloma using epidural phenol injections. Journal of pain and symptom management, 1992, Volume: 7, Issue:3 Topics: Adult; Female; Humans; Injections, Epidural; Multiple Myeloma; Pain, Intractable; Palliative Care; P	1992
Transsacral neurolytic nerve block. An alternative approach to intractable perineal pain. British journal of anaesthesia, 1983, Volume: 55, Issue:9 Topics: Aged; Female; Humans; Male; Middle Aged; Nerve Block; Pain, Intractable; Perineum; Phenol; Phenols;	1983
Neurolysis. Subarachnoid neurolytic blockade. Acta anaesthesiologica Belgica, 1981, Volume: 32, Issue:1 Topics: Ethanol; Humans; Injections, Spinal; Nerve Block; Pain; Pain, Intractable; Phenol; Phenols; Subarach	1981
Intractable pain therapy using a new epidural catheter. JAMA, 1982, Aug-06, Volume: 248, Issue:5 Topics: Adult; Anesthesia, Epidural; Anesthesia, Local; Catheterization; Female; Humans; Injections; Male; M	1982
[Indications of analgesia with absolute alcohol or phenol for intractable pain in thoracic and abdominal cancerous pathology (author's transl)]. Anesthesie, analgesie, reanimation, 1981, Volume: 38, Issue:7-8 Topics: Abdominal Neoplasms; Ethanol; Humans; Nerve Block; Pain, Intractable; Phenol; Phenols; Thoracic Neop	1981
Failure to obtain informed consent to surgery. Case in point: Butler v. South Fulton Medical Center, Inc. 452 S.E.2d 768--GA (1994). The Regan report on nursing law, 1995, Volume: 35, Issue:10 Topics: Female; Georgia; Humans; Informed Consent; Malpractice; Medical Staff, Hospital; Nerve Block; Pain,	1995
Neurolytic thoracic paravertebral block in cancer pain. A clinical report. Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:5 Topics: Acute Disease; Adult; Aged; Analgesics; Anesthetics, Local; Bupivacaine; Chronic Disease; Female; Fo	1998
Mapping the spread of epidural phenol in cancer pain patients by radionuclide admixture and epidural scintigraphy. The Clinical journal of pain, 1992, Volume: 8, Issue:1 Topics: Adult; Aged; Epidural Space; Humans; Injections, Epidural; Middle Aged; Neoplasms; Nerve Block; Pain	1992
Intrathecal phenol rhizotomy for management of pain in recurrent unresectable carcinoma of the rectum. Surgery, gynecology & obstetrics, 1991, Volume: 173, Issue:1 Topics: Adenocarcinoma; Adult; Aged; Female; Humans; Injections, Spinal; Male; Middle Aged; Neoplasm Recurre	1991
[Analgesic therapy of cancer outpatients]. Voprosy onkologii, 1987, Volume: 33, Issue:2 Topics: Adult; Aged; Ambulatory Care; Analgesics; Drug Evaluation; Ethanol; Glycerol; Humans; Middle Aged; N	1987
[Our experience with epidural chemical neurolysis in the treatment of chronic pain syndromes]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1985, Feb-11, Volume: 40, Issue:6 Topics: Anesthesia, Epidural; Chronic Disease; Humans; Nerve Block; Pain, Intractable; Phenol; Phenols	1985
Potential hazards of transcatheter serial epidural phenol neurolysis. Anesthesia and analgesia, 1985, Volume: 64, Issue:12 Topics: Analgesia; Catheterization; Epidural Space; Humans; Male; Middle Aged; Pain, Intractable; Phenol; Ph	1985

phenol and Pain, Intractable

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