phenol has been researched along with Kidney Failure, Chronic in 8 studies
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (12.50) | 18.7374 |
1990's | 2 (25.00) | 18.2507 |
2000's | 2 (25.00) | 29.6817 |
2010's | 3 (37.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Wang, X | 1 |
Hao, Y | 1 |
Liu, X | 1 |
Yu, S | 1 |
Zhang, W | 1 |
Yang, S | 1 |
Yu, Z | 1 |
Ren, F | 1 |
Eidi, F | 1 |
Poor-Reza Gholi, F | 1 |
Ostadrahimi, A | 1 |
Dalili, N | 1 |
Samadian, F | 1 |
Barzegari, A | 1 |
Calaf, R | 1 |
Cerini, C | 1 |
Génovésio, C | 1 |
Verhaeghe, P | 1 |
Jourde-Chiche, N | 1 |
Bergé-Lefranc, D | 1 |
Gondouin, B | 1 |
Dou, L | 1 |
Morange, S | 1 |
Argilés, A | 1 |
Rathelot, P | 1 |
Dignat-George, F | 1 |
Brunet, P | 1 |
Charpiot, P | 1 |
Ye, S | 2 |
Zhong, H | 1 |
Yanamadala, V | 1 |
Campese, VM | 2 |
Capeillère-Blandin, C | 1 |
Gausson, V | 1 |
Nguyen, AT | 1 |
Descamps-Latscha, B | 1 |
Drüeke, T | 1 |
Witko-Sarsat, V | 1 |
Christiansen, RG | 1 |
Klaman, JS | 1 |
Ozgur, B | 1 |
Gasparović, V | 1 |
Kuzmanić, D | 1 |
Brod, J | 1 |
Radonić, M | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Impact of Renal SympAthetic DenerVation on Chronic HypErtension[NCT01628198] | 38 participants (Actual) | Interventional | 2011-10-31 | Terminated (stopped due to recommendation by the study's DSMB due to insufficient data to determine efficacy.) | |||
Renal Sympathetic Denervation for the Management of Chronic Hypertension[NCT01628172] | 96 participants (Actual) | Interventional | 2011-01-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The change in diastolic blood pressure as measured by 24 hour ambulatory monitoring at 6 months as compared to from baseline. (NCT01628198)
Timeframe: baseline and 6 months
Intervention | mmHg mean change (Mean) |
---|---|
Renal Denervation Group | -5.5 |
The change in systolic blood pressure as measured by 24 hour ambulatory monitoring at 6 months as compared to from baseline. (NCT01628198)
Timeframe: baseline and 6 months
Intervention | mmHg (Mean) |
---|---|
Renal Denervation Group | -10.2 |
The total number of anti-hypertensive medications at baseline, 6 months, and 12 months (NCT01628198)
Timeframe: Baseline, 6 months, 12 months
Intervention | medications (Mean) | ||
---|---|---|---|
Baseline | 6 months | 12 months | |
Renal Denervation Group | 5.37 | 4.79 | 4.64 |
A blood urea nitrogen (BUN) test measures the amount of nitrogen in blood that comes from the waste product urea. Urea is made when protein is broken down in the body. Urea is made in the liver and passed out in the urine. (NCT01628198)
Timeframe: baseline, 6 months, 12 months
Intervention | mg/dL (Mean) | ||
---|---|---|---|
Baseline | 6 months | 12 months | |
Renal Denervation Group | 20.82 | 22.15 | 23.11 |
Creatinine measures the level of the waste product in the body. The amount of creatinine in the blood depends partly on the amount of muscle tissue you have. Men generally have higher creatinine levels than women.Normal levels of creatinine in the blood are approximately 0.6 to 1.2 milligrams (mg) per deciliter (dL) in adult males and 0.5 to 1.1 milligrams per deciliter in adult females. High levels of creatinine indicates kidney impairment. (NCT01628198)
Timeframe: baseline, 6 months, 12 months
Intervention | mg/dl (Mean) | ||
---|---|---|---|
Baseline | 6 months | 12 months | |
Renal Denervation Group | 1.6 | 1.68 | 2.03 |
Different time points office diastolic blood pressure measurements (NCT01628198)
Timeframe: baseline, 6 month, 12 months
Intervention | mm Hg (Mean) | ||
---|---|---|---|
Baseline | 6 months | 12 months | |
Renal Denervation Group | 87.06 | 86.93 | 87.75 |
Different time points office systolic blood pressure measurements (NCT01628198)
Timeframe: baseline, 6 month, 12 months
Intervention | mm Hg (Mean) | ||
---|---|---|---|
Baseline | 6 months | 12 months | |
Renal Denervation Group | 156.86 | 151.19 | 158.45 |
Renal artery blood flow as measured by Renal Aortic Ratio (RAR) = Peak systolic Velocity renal artery / Peak Systolic Velocity Aorta. A >60% stenosis is reported when there is a >3.5:1 Renal to Aortic Ratio. (NCT01628198)
Timeframe: Baseline and 12 months
Intervention | ratio (Mean) | |||
---|---|---|---|---|
Baseline Right RAR | Baseline Left RAR | 12 months Right RAR | 12 months Left RAR | |
Renal Denervation Group | 1.38 | 1.52 | 1.41 | 1.52 |
Dimensions of renal artery, right and left (NCT01628198)
Timeframe: baseline and 12 months
Intervention | mm (Mean) | |||
---|---|---|---|---|
Baseline R Kidney | Baseline L Kidney | 12 months R Kidney | 12 months L Kidney | |
Renal Denervation Group | 11.43 | 11.68 | 11.26 | 11.39 |
Renal artery blood flow as measured by Resistive Index. RI = (peak systolic velocity - end diastolic velocity ) / peak systolic velocity. the normal value is ~ 0.60, with 0.70 being around the upper limits of normal (NCT01628198)
Timeframe: Baseline and 12 months
Intervention | index (Mean) | |||
---|---|---|---|---|
Baseline Right RI | Baseline Left RI | 12 months Right RI | 12 months Left RI | |
Renal Denervation Group | 0.67 | 0.72 | 0.72 | 0.72 |
1 trial available for phenol and Kidney Failure, Chronic
Article | Year |
---|---|
Effect of Lactobacillus Rhamnosus on serum uremic toxins (phenol and P-Cresol) in hemodialysis patients: A double blind randomized clinical trial.
Topics: Cresols; Double-Blind Method; Female; Humans; Kidney Failure, Chronic; Lacticaseibacillus rhamnosus; | 2018 |
7 other studies available for phenol and Kidney Failure, Chronic
Article | Year |
---|---|
Gut microbiota from end-stage renal disease patients disrupt gut barrier function by excessive production of phenol.
Topics: Biopsy; Cytokines; Gastrointestinal Microbiome; Humans; Inflammation Mediators; Intestinal Mucosa; K | 2019 |
Determination of uremic solutes in biological fluids of chronic kidney disease patients by HPLC assay.
Topics: Aged; Chromatography, High Pressure Liquid; Cresols; Female; Humans; Indican; Indoleacetic Acids; Ki | 2011 |
Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Clonidine; Denervation; Disease Models, An | 2002 |
Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Clonidine; Denervation; Disease Models, An | 2002 |
Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Clonidine; Denervation; Disease Models, An | 2002 |
Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Clonidine; Denervation; Disease Models, An | 2002 |
Respective role of uraemic toxins and myeloperoxidase in the uraemic state.
Topics: Adult; Case-Control Studies; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Oxidation-R | 2006 |
Successful treatment of phenol poisoning with charcoal hemoperfusion.
Topics: Blood Proteins; Charcoal; Chronic Disease; Female; Hemoperfusion; Humans; Kidney Failure, Chronic; K | 1996 |
Renal afferent impulses, the posterior hypothalamus, and hypertension in rats with chronic renal failure.
Topics: Afferent Pathways; Angiotensin II; Animals; Blood Pressure; Denervation; Hypertension, Renal; Hypoth | 1997 |
Membranoproliferative glomerulonephritis in a patient with multiple myeloma and phenol intoxication.
Topics: Adult; Female; Glomerulonephritis; Humans; Kidney Failure, Chronic; Multiple Myeloma; Phenol; Phenol | 1985 |