Page last updated: 2024-10-19

phenol and Innate Inflammatory Response

phenol has been researched along with Innate Inflammatory Response in 33 studies

Research Excerpts

ExcerptRelevanceReference
" This study investigated the effects of a topically applied FO preparation (FOP) on phenol-induced ear edema and evaluated the percutaneous penetration of FOP in ear tissue."7.96Fish oil preparation inhibits leukocyte recruitment and bands that characterize inflamed tissue in a model of phenol-induced skin inflammation: percutaneous penetration of a topically applied preparation demonstrated by photoacoustic spectroscopy. ( Ambrósio da Rocha, B; Ames, FQ; Aparecida Bersani-Amado, C; Bracht, L; Kenji Nakamura Cuman, R; Luciano Baesso, M; Oliveira, LA; Parreira de Lima, E; Sato, F; Vizioli de Castro-Hoshino, L, 2020)
" We examined urinary phenol (bisphenol A (BPA), triclosan (TCS), benzophenone-3 (BP-3), 2,4-dichlorophenol (24-DCP), 2,5-dichlorophenol (25-DCP)) and paraben (butyl paraben (B-PB), methyl paraben (M-PB), propyl paraben (P-PB)) concentrations measured three times during pregnancy in relation to markers of oxidative stress and inflammation among participants in the Puerto Rico Testsite for Exploring Contamination Threats (PROTECT) project."7.81Associations between urinary phenol and paraben concentrations and markers of oxidative stress and inflammation among pregnant women in Puerto Rico. ( Alshawabkeh, AN; Anzalota Del Toro, LV; Cordero, JF; Ferguson, KK; Meeker, JD; Watkins, DJ, 2015)
"Athletes are increasingly consuming (poly)phenol supplements to modify oxidative stress and/or exercise-induced inflammation, in the hope that this will enhance exercise performance."5.41How can chokeberry ( ( Ali Redha, A; Cerullo, G; Clifford, T; Kimble, R; Zare, R, 2023)
"Oils rich in phenols, whether natural (VOO) or artificially added (SOP), reduce postprandial inflammation, compared with seed oil (sunflower)."5.16The postprandial inflammatory response after ingestion of heated oils in obese persons is reduced by the presence of phenol compounds. ( Alcala-Diaz, JF; Camargo, A; Delgado-Lista, J; Fernandez-Real, JM; Garcia-Olid, B; Lopez-Miranda, J; Lopez-Segura, F; Luque de Castro, MD; Moreno-Navarrete, JM; Muñoz-Lopez, C; Perez-Herrera, A; Perez-Jimenez, F; Quintana-Navarro, GM; Rangel-Zuñiga, OA; Torres-Sanchez, LA, 2012)
" Among many treatment options for pilonidal sinus, instillation of crystalloid phenol showed promising results in terms of low recurrence rates, low post-operative complications and less healing time."4.31A case report of sacrococcygeal foreign body presenting as pilonidal sinus. ( Afzal, A; Ammar, AS; Anjum, MA; Naqi, SA; Sarwar, MZ; Sohail, R, 2023)
" staudtii stem bark, as well as protocatechuic acid and betulinic acid isolated from the bioactive ethyl acetate fraction were evaluated in different mice models of inflammation and pain; furthermore, antioxidant assays were carried out."4.02Isolation and characterization of anti-inflammatory and analgesic compounds from Uapaca staudtii Pax (Phyllanthaceae) stem bark. ( Ajibesin, K; Akpan, O; Archibong, B; De Leo, M; Eseyin, O; Essien, E; Etukudo, E; Flamini, G; Thomas, P; Udoh, A, 2021)
" This study investigated the effects of a topically applied FO preparation (FOP) on phenol-induced ear edema and evaluated the percutaneous penetration of FOP in ear tissue."3.96Fish oil preparation inhibits leukocyte recruitment and bands that characterize inflamed tissue in a model of phenol-induced skin inflammation: percutaneous penetration of a topically applied preparation demonstrated by photoacoustic spectroscopy. ( Ambrósio da Rocha, B; Ames, FQ; Aparecida Bersani-Amado, C; Bracht, L; Kenji Nakamura Cuman, R; Luciano Baesso, M; Oliveira, LA; Parreira de Lima, E; Sato, F; Vizioli de Castro-Hoshino, L, 2020)
" We examined urinary phenol (bisphenol A (BPA), triclosan (TCS), benzophenone-3 (BP-3), 2,4-dichlorophenol (24-DCP), 2,5-dichlorophenol (25-DCP)) and paraben (butyl paraben (B-PB), methyl paraben (M-PB), propyl paraben (P-PB)) concentrations measured three times during pregnancy in relation to markers of oxidative stress and inflammation among participants in the Puerto Rico Testsite for Exploring Contamination Threats (PROTECT) project."3.81Associations between urinary phenol and paraben concentrations and markers of oxidative stress and inflammation among pregnant women in Puerto Rico. ( Alshawabkeh, AN; Anzalota Del Toro, LV; Cordero, JF; Ferguson, KK; Meeker, JD; Watkins, DJ, 2015)
" L-NAME injection, however, did not suppress phenol-induce irritant inflammation."3.69Modulation of picryl chloride-induced contact hypersensitivity reaction in mice by nitric oxide. ( Hori, M; Kitano, Y; Morita, H, 1996)
" Finally, the study of theoretical physicochemical properties, the observation of low toxicity (hemolysis assay), and the evaluation of oral bioavailability of the TP derivative showed that it is a possible anti-inflammatory drug candidate."1.51 ( Castro, RI; Morales-Quintana, L; Valenzuela-Riffo, F, 2019)
"Neuroinflammation is an integral part of the neurodegeneration process inherent to several aging dysfunctions."1.46Bioaccessible (poly)phenol metabolites from raspberry protect neural cells from oxidative stress and attenuate microglia activation. ( Brites, D; Ferreira, RB; Figueira, I; Garcia, G; Ivanov, I; McDougall, GJ; Nanni, S; Pinto, P; Santos, CN; Silva, RF; Stewart, D, 2017)
"Erianin is a natural product isolated from Dendrobium chrysotoxum Lindl."1.46Erianin inhibits indoleamine 2, 3-dioxygenase -induced tumor angiogenesis. ( Cao, Y; Liu, J; Su, C; Zhang, P, 2017)
"A series of potent and orally bioavailable 3,4-diaminocyclobutenediones with various amide modifications and substitution on the left side phenyl ring were prepared and found to show significant inhibitory activities towards both CXCR2 and CXCR1 receptors."1.35Diaminocyclobutenediones as potent and orally bioavailable CXCR2 receptor antagonists: SAR in the phenolic amide region. ( Aki, C; Biju, P; Chao, J; Dwyer, MP; Fan, X; Ferreira, JA; Fine, J; Fosseta, J; Gonsiorek, W; Hipkin, RW; Lai, G; Lundell, D; Merritt, RJ; Rindgen, D; Taveras, AG; Wu, M; Yu, Y, 2009)
"Pre-treatment with gallic acid significantly rendered K562 cells more susceptible to NK cell-mediated necrosis, while pre-treatment with rutin significantly rendered K562 cells more susceptible to apoptosis."1.33Effect of phenols on natural killer (NK) cell-mediated death in the K562 human leukemic cell line. ( Andrikopoulos, NK; Dedoussis, GV; Kaliora, AC, 2005)
"pHA-lysine was detected in inflamed human tissues that were reduced, hydrolyzed, and then analyzed by mass spectrometry, indicating that the reaction of pHA with proteins may be of physiological importance."1.30p-Hydroxyphenylacetaldehyde, the major product of L-tyrosine oxidation by the myeloperoxidase-H2O2-chloride system of phagocytes, covalently modifies epsilon-amino groups of protein lysine residues. ( Crowley, JR; d'Avignon, A; Gaut, JP; Hazen, SL; Heinecke, JW; Hsu, FF, 1997)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.06)18.7374
1990's2 (6.06)18.2507
2000's6 (18.18)29.6817
2010's13 (39.39)24.3611
2020's10 (30.30)2.80

Authors

AuthorsStudies
Lieke, T1
Steinberg, CEW1
Meinelt, T1
Knopf, K1
Kloas, W1
Anjum, MA1
Ammar, AS1
Naqi, SA1
Afzal, A1
Sarwar, MZ1
Sohail, R1
Zare, R1
Kimble, R1
Ali Redha, A1
Cerullo, G1
Clifford, T1
Cheng, Y1
Wu, T1
Tang, S1
Liang, F1
Fang, Y1
Cao, W1
Pan, S1
Xu, X1
Hegedűs, C1
Muresan, M1
Badale, A1
Bombicz, M1
Varga, B1
Szilágyi, A1
Sinka, D1
Bácskay, I1
Popoviciu, M1
Magyar, I1
Szarvas, MM1
Szőllősi, E1
Németh, J1
Szilvássy, Z1
Pallag, A1
Kiss, R1
Kiyama, R1
Juwita, T1
H P Pakpahan, W1
M Puspitasari, I1
Mekar Saptarini, N1
Levita, J1
Thomas, P1
Essien, E1
Udoh, A1
Archibong, B1
Akpan, O1
Etukudo, E1
De Leo, M1
Eseyin, O1
Flamini, G1
Ajibesin, K1
Chojnacka, K1
Owczarek, K1
Caban, M1
Sosnowska, D1
Polka, D1
Koziolkiewicz, M1
Fichna, J1
Lewandowska, U1
Ajayi, AM1
Ologe, MO1
Ben-Azu, B1
Okhale, SE1
Adzu, B1
Ademowo, OG1
Wu, SY1
Fu, YH1
Zhou, Q1
Bai, M1
Chen, GY1
Zhao, SY1
Han, CR1
Song, XP1
Aparicio-Soto, M1
Montserrat-de la Paz, S1
Sanchez-Hidalgo, M1
Cardeno, A1
Bermudez, B1
Muriana, FJG1
Alarcon-de-la-Lastra, C1
Ames, FQ1
Bracht, L1
Sato, F1
Vizioli de Castro-Hoshino, L1
Ambrósio da Rocha, B1
Oliveira, LA1
Parreira de Lima, E1
Kenji Nakamura Cuman, R1
Luciano Baesso, M1
Aparecida Bersani-Amado, C1
Castro, RI1
Valenzuela-Riffo, F1
Morales-Quintana, L1
Kumar, P1
Choonara, YE1
Modi, G1
Naidoo, D1
Pillay, V1
Leow, SS1
Sekaran, SD1
Sundram, K1
Tan, Y1
Sambanthamurthi, R1
Watkins, DJ1
Ferguson, KK1
Anzalota Del Toro, LV1
Alshawabkeh, AN1
Cordero, JF1
Meeker, JD1
Ahmad, N1
Bhatnagar, S1
Ali, SS1
Dutta, R1
Garcia, G1
Nanni, S1
Figueira, I1
Ivanov, I1
McDougall, GJ1
Stewart, D1
Ferreira, RB1
Pinto, P1
Silva, RF1
Brites, D1
Santos, CN1
Su, C1
Zhang, P1
Liu, J1
Cao, Y1
Kontogiorgis, C1
Mantzanidou, M1
Hadjipavlou-Litina, D1
Aki, C1
Chao, J2
Ferreira, JA1
Dwyer, MP1
Yu, Y1
Merritt, RJ1
Lai, G1
Wu, M1
Hipkin, RW1
Fan, X1
Gonsiorek, W1
Fosseta, J1
Rindgen, D1
Fine, J1
Lundell, D1
Taveras, AG1
Biju, P1
Tripisciano, C1
Kozynchenko, OP1
Linsberger, I1
Phillips, GJ1
Howell, CA1
Sandeman, SR1
Tennison, SR1
Mikhalovsky, SV1
Weber, V1
Falkenhagen, D1
Perez-Herrera, A1
Delgado-Lista, J1
Torres-Sanchez, LA1
Rangel-Zuñiga, OA1
Camargo, A1
Moreno-Navarrete, JM1
Garcia-Olid, B1
Quintana-Navarro, GM1
Alcala-Diaz, JF1
Muñoz-Lopez, C1
Lopez-Segura, F1
Fernandez-Real, JM1
Luque de Castro, MD1
Lopez-Miranda, J1
Perez-Jimenez, F1
Pitt, D1
Aubin, JM1
Dedoussis, GV1
Kaliora, AC1
Andrikopoulos, NK1
Macedo, SM1
Lourenço, EL1
Borelli, P1
Fock, RA1
Ferreira, JM1
Farsky, SH1
Olas, B1
Nowak, P1
Ponczek, M1
Wachowicz, B1
Morita, H1
Hori, M1
Kitano, Y1
Hazen, SL1
Gaut, JP1
Hsu, FF1
Crowley, JR1
d'Avignon, A1
Heinecke, JW1
Waltz, SE1
Eaton, L1
Toney-Earley, K1
Hess, KA1
Peace, BE1
Ihlendorf, JR1
Wang, MH1
Kaestner, KH1
Degen, SJ1
Anton-Athens, V1
Ketai, DL1
Gaughan, RN1
Otto, RA1
Renner, GJ1
Templer, JW1
Davis, WE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparative Effect Of Different Oils For Frying On The Endothelial Function, The Oxidative Stress And The Postprandial Inflammatory Response[NCT00837317]26 participants (Actual)Interventional2009-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for phenol and Innate Inflammatory Response

ArticleYear
How can chokeberry (
    Food & function, 2023, Jun-19, Volume: 14, Issue:12

    Topics: Athletes; Athletic Performance; Dietary Supplements; Humans; Inflammation; Iron; Phenol; Phenols; Ph

2023
Nutritional implications of ginger: chemistry, biological activities and signaling pathways.
    The Journal of nutritional biochemistry, 2020, Volume: 86

    Topics: Animals; Blood Pressure; Cholesterol; Cytoskeleton; Diabetes Mellitus; Dysmenorrhea; Epigenesis, Gen

2020
Chalcones and their potential role in inflammation.
    Mini reviews in medicinal chemistry, 2008, Volume: 8, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Chalcones; Chemistry, Pharmaceutical; Drug Design;

2008

Trials

1 trial available for phenol and Innate Inflammatory Response

ArticleYear
The postprandial inflammatory response after ingestion of heated oils in obese persons is reduced by the presence of phenol compounds.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:3

    Topics: Antioxidants; Cross-Over Studies; Dimethylpolysiloxanes; Fatty Acids, Monounsaturated; Food Handling

2012

Other Studies

29 other studies available for phenol and Innate Inflammatory Response

ArticleYear
Modification of the chemically induced inflammation assay reveals the Janus face of a phenol rich fulvic acid.
    Scientific reports, 2022, 04-07, Volume: 12, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Benzopyrans; Copper; Humic Substances; Inflammation; Larva; Pheno

2022
A case report of sacrococcygeal foreign body presenting as pilonidal sinus.
    JPMA. The Journal of the Pakistan Medical Association, 2023, Volume: 73, Issue:2

    Topics: Adolescent; Crystalloid Solutions; Female; Foreign Bodies; Humans; Inflammation; Male; Phenol; Pheno

2023
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice.
    Food & function, 2020, Apr-01, Volume: 11, Issue:4

    Topics: Animals; Blueberry Plants; Diet, High-Fat; Fermentation; Gene Expression Regulation; Ileum; Inflamma

2020
SIRT1 Activation by
    Molecules (Basel, Switzerland), 2020, May-29, Volume: 25, Issue:11

    Topics: Adiposity; Alkaloids; Animals; Blood Glucose; Body Weight; Chromatography, High Pressure Liquid; Dia

2020
Anti-inflammatory Activity of
    Pakistan journal of biological sciences : PJBS, 2020, Volume: 23, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Flowers; Gastric Mucosa; Inflam

2020
Isolation and characterization of anti-inflammatory and analgesic compounds from Uapaca staudtii Pax (Phyllanthaceae) stem bark.
    Journal of ethnopharmacology, 2021, Apr-06, Volume: 269

    Topics: Africa, Western; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Betu

2021
Japanese quince (Chaenomeles japonica) leaf phenol extract as modulator of the inflammatory response in lipopolysaccharide-triggered murine macrophage RAW 264.7 cells.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2020, Volume: 71, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Inflammation; Inflammation Mediators; Lipopolysaccharides; Macrop

2020
Ocimum gratissimum Linn. Leaf extract inhibits free radical generation and suppressed inflammation in carrageenan-induced inflammation models in rats.
    Journal of basic and clinical physiology and pharmacology, 2017, Nov-27, Volume: 28, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Disease Models, Animal; Dose-Response

2017
Bioactive Phenolic and Isocoumarin Glycosides from the Stems of Homalium paniculiflorum.
    Molecules (Basel, Switzerland), 2018, Feb-22, Volume: 23, Issue:2

    Topics: Animals; Glycosides; Humans; Inflammation; Isocoumarins; Lipopolysaccharides; Mice; Nitric Oxide; Ph

2018
Virgin olive oil and its phenol fraction modulate monocyte/macrophage functionality: a potential therapeutic strategy in the treatment of systemic lupus erythematosus.
    The British journal of nutrition, 2018, Volume: 120, Issue:6

    Topics: Animals; Cytokines; Diet; Female; Humans; Immunity, Innate; Inflammation; Lipopolysaccharides; Lupus

2018
Fish oil preparation inhibits leukocyte recruitment and bands that characterize inflamed tissue in a model of phenol-induced skin inflammation: percutaneous penetration of a topically applied preparation demonstrated by photoacoustic spectroscopy.
    Natural product research, 2020, Volume: 34, Issue:16

    Topics: Administration, Topical; Animals; Disease Models, Animal; Ear; Edema; Fish Oils; Inflammation; Leuko

2020
    BioMed research international, 2019, Volume: 2019

    Topics: Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Computer Simulation; Cyclooxygenase 2; E

2019
Cur(Que)min: a neuroactive permutation of curcumin and quercetin for treating spinal cord injury.
    Medical hypotheses, 2014, Volume: 82, Issue:4

    Topics: Antioxidants; Curcumin; Glutathione Transferase; Humans; Inflammation; Models, Theoretical; Neuropro

2014
Gene expression changes in spleens and livers of tumour-bearing mice suggest delayed inflammation and attenuated cachexia in response to oil palm phenolics.
    Journal of nutrigenetics and nutrigenomics, 2013, Volume: 6, Issue:6

    Topics: Animals; Cachexia; Dietary Supplements; Gallic Acid; Gene Expression Profiling; Gene Expression Regu

2013
Associations between urinary phenol and paraben concentrations and markers of oxidative stress and inflammation among pregnant women in Puerto Rico.
    International journal of hygiene and environmental health, 2015, Volume: 218, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Benzhydryl Compounds; Benzophenones; Biomarkers; Bod

2015
Phytofabrication of bioinduced silver nanoparticles for biomedical applications.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Biomedical Technology; Disease

2015
Bioaccessible (poly)phenol metabolites from raspberry protect neural cells from oxidative stress and attenuate microglia activation.
    Food chemistry, 2017, Jan-15, Volume: 215

    Topics: Hydrogen Peroxide; Inflammation; Lipopolysaccharides; Macrophage Activation; Microglia; Neurons; Nit

2017
Erianin inhibits indoleamine 2, 3-dioxygenase -induced tumor angiogenesis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 88

    Topics: Animals; Bibenzyls; Calibration; Carcinoma, Lewis Lung; Cell Line, Tumor; Human Umbilical Vein Endot

2017
Diaminocyclobutenediones as potent and orally bioavailable CXCR2 receptor antagonists: SAR in the phenolic amide region.
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Administration, Oral; Amides; Animals; Area Under Curve; Chemistry, Pharmaceutical; Cyclobutanes; Di

2009
Activation-dependent adsorption of cytokines and toxins related to liver failure to carbon beads.
    Biomacromolecules, 2011, Oct-10, Volume: 12, Issue:10

    Topics: Adsorption; Bilirubin; Carbon; Cholates; Humans; Inflammation; Interleukin-6; Liver Failure, Acute;

2011
Joseph Lister: father of modern surgery.
    Canadian journal of surgery. Journal canadien de chirurgie, 2012, Volume: 55, Issue:5

    Topics: Amputation, Surgical; Disinfectants; Fermentation; Fractures, Open; General Surgery; Germ Theory of

2012
Effect of phenols on natural killer (NK) cell-mediated death in the K562 human leukemic cell line.
    Cell biology international, 2005, Volume: 29, Issue:11

    Topics: Annexin A5; Annexins; Apoptosis; Cell Death; Cell Line, Tumor; Cell Separation; Coculture Techniques

2005
Effect of in vivo phenol or hydroquinone exposure on events related to neutrophil delivery during an inflammatory response.
    Toxicology, 2006, Mar-15, Volume: 220, Issue:2-3

    Topics: Animals; Glycogen; Hydroquinones; Inflammation; Leukocyte Count; Leukocyte Rolling; Leukocytes; Male

2006
Resveratrol, a natural phenolic compound may reduce carbonylation proteins induced by peroxynitrite in blood platelets.
    General physiology and biophysics, 2006, Volume: 25, Issue:2

    Topics: Antioxidants; Blood Platelets; Carbon; Colorimetry; Enzyme-Linked Immunosorbent Assay; Humans; Infla

2006
Modulation of picryl chloride-induced contact hypersensitivity reaction in mice by nitric oxide.
    The Journal of investigative dermatology, 1996, Volume: 107, Issue:4

    Topics: Animals; Dermatitis, Contact; Ear; Female; Immunization; Inflammation; Irritants; Mice; Mice, Inbred

1996
p-Hydroxyphenylacetaldehyde, the major product of L-tyrosine oxidation by the myeloperoxidase-H2O2-chloride system of phagocytes, covalently modifies epsilon-amino groups of protein lysine residues.
    The Journal of biological chemistry, 1997, Jul-04, Volume: 272, Issue:27

    Topics: Acetaldehyde; Amino Acids; Animals; Cattle; Chlorides; Chromatography, High Pressure Liquid; Humans;

1997
Ron-mediated cytoplasmic signaling is dispensable for viability but is required to limit inflammatory responses.
    The Journal of clinical investigation, 2001, Volume: 108, Issue:4

    Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Dermatitis, Allergic Contact; Dermatiti

2001
Use of Cortisporin Otic Solution in phenol nail surgery.
    Journal of the American Podiatric Medical Association, 1985, Volume: 75, Issue:1

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Drug Combinations; Human

1985
The effect of sterile inflammation on skin flap survival.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1986, Volume: 95, Issue:1

    Topics: Animals; Chemexfoliation; Croton Oil; Dermatologic Surgical Procedures; Graft Survival; Hexachloroph

1986