phenobarbital has been researched along with Weight Gain in 10 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The fatty liver induced by orotic acid and a high sucrose diet in male rats was prevented by the administration of DHEA and/or phenobarbital (PB)." | 7.70 | Prevention of orotic-acid-induced fatty liver in male rats by dehydroepiandrosterone and/or phenobarbital. ( Goto, H; Makita, T; Yamashita, S, 1998) |
| " The fatty liver induced by orotic acid and a high sucrose diet in male rats was prevented by the administration of DHEA and/or phenobarbital (PB)." | 3.70 | Prevention of orotic-acid-induced fatty liver in male rats by dehydroepiandrosterone and/or phenobarbital. ( Goto, H; Makita, T; Yamashita, S, 1998) |
| "Propiconazole produced an increase incidence of liver tumors in male CD-1 mice only at a dose that exceeded the maximum tolerated dose (2500 ppm)." | 1.40 | Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action. ( Currie, RA; Goetz, AK; Goodman, JI; Omiecinski, CJ; Peffer, RC, 2014) |
| "Absence status was aggravated with carbamazepine and generalised tonic-clonic seizures were not controlled with ethosuximide." | 1.36 | Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status. ( Genton, P; Velizarova, R, 2010) |
| " Oral administration of phenobarbital enhanced the toxic effect of RM on (b), (d) and (e) and did not modify the toxic effect of RM on (a), (c) and (f)." | 1.28 | Glucosinolates toxicity in growing rats: interactions with the hepatic detoxification system. ( Nugon-Baudon, L; Rabot, S; Raibaud, P; Szylit, O, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smirk, CL | 1 |
| Bowman, E | 1 |
| Doyle, LW | 1 |
| Kamlin, O | 1 |
| Currie, RA | 1 |
| Peffer, RC | 1 |
| Goetz, AK | 1 |
| Omiecinski, CJ | 1 |
| Goodman, JI | 1 |
| Gelderblom, WC | 1 |
| Marasas, WF | 1 |
| Lebepe-Mazur, S | 1 |
| Swanevelder, S | 1 |
| Abel, S | 1 |
| Velizarova, R | 1 |
| Genton, P | 1 |
| Manent, JB | 1 |
| Jorquera, I | 1 |
| Franco, V | 1 |
| Ben-Ari, Y | 1 |
| Perucca, E | 1 |
| Represa, A | 1 |
| Laviola, G | 1 |
| Terranova, ML | 1 |
| Sedowofia, K | 1 |
| Clayton, R | 1 |
| Manning, A | 1 |
| Saito, M | 1 |
| Yamaguchi, M | 1 |
| Rabot, S | 2 |
| Nugon-Baudon, L | 2 |
| Szylit, O | 2 |
| Goto, H | 1 |
| Yamashita, S | 1 |
| Makita, T | 1 |
| Raibaud, P | 1 |
10 other studies available for phenobarbital and Weight Gain
| Article | Year |
|---|---|
Home-based detoxification for neonatal abstinence syndrome reduces length of hospital admission without prolonging treatment.
Topics: Adult; Analgesics, Opioid; Breast Feeding; Cost Control; Female; Home Care Services, Hospital-Based; | 2014 |
Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Cell Proliferation; Constitutive Androstane Receptor; F | 2014 |
Cancer initiating properties of fumonisin B1 in a short-term rat liver carcinogenesis assay.
Topics: Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Diet; Enzyme Induction; Fumonisins; Glutat | 2008 |
Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Diagnosis, Differential; Dose-Response Relationship, D | 2010 |
Antiepileptic drugs and brain maturation: fetal exposure to lamotrigine generates cortical malformations in rats.
Topics: Animals; Anticonvulsants; Brain; Cell Count; Cell Movement; Dose-Response Relationship, Drug; Female | 2008 |
A mouse model of early social interactions after prenatal drug exposure: a genetic investigation.
Topics: Animals; Exploratory Behavior; Female; Genetics, Behavioral; Genotype; Grooming; Interpersonal Relat | 1994 |
Response of liver microsomal mixed-function oxidases to dietary linoleic acid levels in rats.
Topics: Animals; Dietary Fats, Unsaturated; Enzyme Induction; Fatty Acids; Linoleic Acid; Linoleic Acids; Li | 1993 |
Alterations of the hepatic xenobiotic-metabolizing enzymes by a glucosinolate-rich diet in germ-free rats: influence of a pre-induction with phenobarbital.
Topics: Animals; Brassica; Cytochrome P-450 Enzyme System; Germ-Free Life; Glucosinolates; Glucuronosyltrans | 1993 |
Prevention of orotic-acid-induced fatty liver in male rats by dehydroepiandrosterone and/or phenobarbital.
Topics: Analysis of Variance; Animals; Cells, Cultured; Dehydroepiandrosterone; Dietary Sucrose; Energy Inta | 1998 |
Glucosinolates toxicity in growing rats: interactions with the hepatic detoxification system.
Topics: Animals; Brassica; Cytochrome P-450 Enzyme System; Diet; Eating; Glucosinolates; Glucuronosyltransfe | 1990 |