Page last updated: 2024-11-02

phenobarbital and Vomiting

phenobarbital has been researched along with Vomiting in 31 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
" The seizures were controlled by phenobarbital."3.88[Vomiting associated with weight stagnation and convulsions: urea cycle disorder should be suspected]. ( Abilkacem, R; Agadr, A; Boujrad, S; Hasbaoui, BE, 2018)
" Hence we feel that daily low-dose phenobarbital therapy is a safe and effective therapy in preventing episodes of cyclic vomiting in children."3.69Use of barbiturates in the treatment of cyclic vomiting during childhood. ( Brady, L; Gokhale, R; Huttenlocher, PR; Kirschner, BS, 1997)
" Four patients experienced relapse with a decreased dosage of valproate."2.74Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate. ( Amakata, K; Fujii, Y; Hikita, T; Kaga, F; Kaneko, S; Kodama, H; Nakamoto, N; Ogita, K; Yanagawa, Y, 2009)
"The syndrome is characterized by a clinical ictal triad of nocturnal seizures, tonic deviation of the eyes, and vomiting."1.28Benign nocturnal childhood occipital epilepsy: a new syndrome with nocturnal seizures, tonic deviation of the eyes, and vomiting. ( Panayiotopoulos, CP, 1989)
"The critical vomiting is always sudden, projectile, and lasts a short period."1.27[Vomiting: symptom of an epileptic seizure]. ( Aguglia, U; De Carvalho, GV; Farnarier, G; Tinuper, P, 1983)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199024 (77.42)18.7374
1990's1 (3.23)18.2507
2000's4 (12.90)29.6817
2010's1 (3.23)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Ogata, M1
Shimizu, D1
Ichikawa, S1
Araki, S1
Esumi, G1
Yamamoto, J1
Kusuhara, K1
Hasbaoui, BE1
Boujrad, S1
Abilkacem, R1
Agadr, A1
Jackson, R1
Toubia, N1
Dhaliwal, G1
Bottomley, SS1
Bronze, MS1
Hikita, T2
Kodama, H2
Nakamoto, N2
Kaga, F1
Amakata, K1
Ogita, K2
Kaneko, S2
Fujii, Y2
Yanagawa, Y2
Fujita, Y1
Suzuki, Y1
Igarashi, K1
YAMASHITA, Y1
WONG, LC1
HEIMBACH, MD1
TRUSCOTT, DR1
DUNCAN, BD1
WEBSTER, JL1
PICKERING, D1
SATOMI, M1
SAFRONOV, EI1
Tinuper, P1
Aguglia, U1
Farnarier, G1
De Carvalho, GV1
Seghieri, G1
De Giorgio, LA1
Innocenti, F1
Pettiná, G1
Zolfanelli, F1
Apicella, P1
Gokhale, R1
Huttenlocher, PR1
Brady, L1
Kirschner, BS1
Stonehewer, J1
Mackin, AJ1
Tasker, S1
Simpson, JW1
Mayhew, IG1
Bruntsch, U1
Diehl, LW1
Hassan, MN1
Laljee, HC1
Parsonage, MJ1
Erith, MJ1
Zelson, C1
Panayiotopoulos, CP1
Menzies, DG1
Busuttil, A1
Prescott, LF1
Gumbart, CH1
Sorensen, SH1
Bickers, JN1
Cereghino, JJ1
Brock, JT1
Van Meter, JC1
Penry, JK1
Smith, LD1
Fisher, P1
Ellenberg, J1
Gordon, NH1
Turner, DJ1
Yamamoto, K1
Sawada, T1
Naito, Y1
Kido, R1
Reddy, AM1
Harper, RG1
Stern, G1
Bwibo, NO1
Durdević, M1
Nikolić, M1
Gladtke, E1
Solc, J1
Sauerová, Z1
Curley, A1
Garrettson, LK1

Trials

3 trials available for phenobarbital and Vomiting

ArticleYear
Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate.
    Brain & development, 2009, Volume: 31, Issue:6

    Topics: Anticonvulsants; Child; Child, Preschool; Dehydration; Dose-Response Relationship, Drug; Drug Admini

2009
Evaluation of albutoin as an antiepileptic drug.
    Clinical pharmacology and therapeutics, 1974, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Allyl Compounds; Analysis of Variance; Anticonvulsants; Appetite; Biopharmaceutic

1974
Oral paediatric premedication. A comparative trial of either phenobarbitone, trimeprazine or diazepam with hyoscine, prior to guillotine tonsillectomy.
    British journal of anaesthesia, 1969, Volume: 41, Issue:2

    Topics: Amnesia; Anesthesia, Inhalation; Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Female

1969

Other Studies

28 other studies available for phenobarbital and Vomiting

ArticleYear
Early diagnosis of neonatal-onset cyclic vomiting syndrome.
    Nagoya journal of medical science, 2023, Volume: 85, Issue:2

    Topics: Early Diagnosis; Female; Humans; Infant; Infant, Newborn; Migraine Disorders; Phenobarbital; Vomitin

2023
[Vomiting associated with weight stagnation and convulsions: urea cycle disorder should be suspected].
    The Pan African medical journal, 2018, Volume: 31

    Topics: Adolescent; Anticonvulsants; Body Weight; Failure to Thrive; Female; Headache; Humans; Hyperammonemi

2018
A confusing case of confusion. Acute porphyrias.
    The Journal of the Oklahoma State Medical Association, 2008, Volume: 101, Issue:4

    Topics: Acidosis, Lactic; Acute Disease; Anticonvulsants; Brain; Confusion; Diagnosis, Differential; Diet, R

2008
[The effect of prophylactic therapy with valproate sodium and phenobarbital in two patients with cyclic vomiting syndrome].
    No to hattatsu = Brain and development, 2008, Volume: 40, Issue:5

    Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Male; Phenobarbital; Valproic Ac

2008
[VOMITING IN INFANTS AND PREVENTIVE MEASURES, WITH SPECIAL REFERENCE TO INTESTINAL OBSTRUCTION].
    [Chiryo] [Therapy], 1963, Volume: 45

    Topics: Atropine; Chlorpromazine; Esophageal Achalasia; Humans; Infant; Infant, Newborn; Intestinal Obstruct

1963
BORIC ACID POISONING: REPORT OF 11 CASES.
    Canadian Medical Association journal, 1964, Apr-25, Volume: 90

    Topics: Acidosis; Anti-Bacterial Agents; Borates; Boric Acids; Color Perception Tests; Dehydration; Diarrhea

1964
ACUTE MUSHROOM POISONING: TREATMENT WITH CURARE AND INTERMITTENT POSITIVE PRESSURE RESPIRATION.
    Clinical pediatrics, 1964, Volume: 3

    Topics: Agaricales; Atropine; Child; Curare; Drug Therapy; Edema; Gastric Lavage; Mushroom Poisoning; Neosti

1964
[VOMITING IN CHILDREN. 1].
    [Chiryo] [Therapy], 1964, Volume: 46

    Topics: Ammonium Chloride; Anesthetics; Atropine; Child; Chlorpromazine; Drug Therapy; Humans; Infant; Pheno

1964
[A CASE OF RADIATION SICKNESS CAUSED BY INTERNAL IRRADIATION].
    Meditsinskaia radiologiia, 1964, Volume: 9

    Topics: 17-Ketosteroids; Blood Cell Count; Blood Pressure; Blood Protein Electrophoresis; Blood Sedimentatio

1964
[Vomiting: symptom of an epileptic seizure].
    Revue d'electroencephalographie et de neurophysiologie clinique, 1983, Volume: 13, Issue:2

    Topics: Adult; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Hu

1983
[Description of a case of a syndrome similar to Reye's syndrome in a male adult undergoing treatment with valproic acid and phenobarbital].
    Giornale di clinica medica, 1982, Volume: 63, Issue:9

    Topics: Adult; Brain Diseases; Coma; Epilepsy, Tonic-Clonic; Fever; Humans; Male; Muscle Rigidity; Phenobarb

1982
Use of barbiturates in the treatment of cyclic vomiting during childhood.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 25, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Mal

1997
Idiopathic phenobarbital-responsive hypersialosis in the dog: an unusual form of limbic epilepsy?
    The Journal of small animal practice, 2000, Volume: 41, Issue:9

    Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Epilepsy; Female; Limbic System; Male; Phenobarbital;

2000
[Therapy of vomiting due to cytostatic treatment].
    MMW, Munchener medizinische Wochenschrift, 1979, Nov-02, Volume: 121, Issue:44

    Topics: Antiemetics; Antineoplastic Agents; Antipsychotic Agents; Autogenic Training; Dronabinol; Humans; Hy

1979
[Anticonvulsants and simultaneous medication - a problem in pregnancy (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1977, Jun-24, Volume: 119, Issue:25

    Topics: Adult; Anticonvulsants; Antiemetics; Dihydroergotamine; Drug Combinations; Drug Interactions; Drug T

1977
Sodium valproate in the treatment of resistant epilepsy.
    Acta neurologica Scandinavica, 1976, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Alopecia; Anticonvulsants; Body Weight; Diarrhea; Drug Interactions; Epilepsies,

1976
Letter: Withdrawal symptoms in newborn infants of epileptic mothers.
    British medical journal, 1975, Jul-05, Volume: 3, Issue:5974

    Topics: Epilepsy; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Pheno

1975
Acute management of neonatal addiction.
    Addictive diseases, 1975, Volume: 2, Issue:1-2

    Topics: Antidiarrheals; Chlorpromazine; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant

1975
Benign nocturnal childhood occipital epilepsy: a new syndrome with nocturnal seizures, tonic deviation of the eyes, and vomiting.
    Journal of child neurology, 1989, Volume: 4, Issue:1

    Topics: Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Male; Nystagmus

1989
Fatal pulmonary aspiration of oral activated charcoal.
    BMJ (Clinical research ed.), 1988, Aug-13, Volume: 297, Issue:6646

    Topics: Charcoal; Death, Sudden; Humans; Male; Middle Aged; Phenobarbital; Pneumonia, Aspiration; Respirator

1988
A comparison of metoclopramide vs. droperidol/phenobarbital for emesis induced by chemotherapy.
    The American journal of the medical sciences, 1987, Volume: 293, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Droperido

1987
[Neuropharmacologic study on the effect of nitrazepam on the central nervous system].
    No to shinkei = Brain and nerve, 1969, Volume: 21, Issue:5

    Topics: Aggression; Amygdala; Animals; Appetitive Behavior; Behavior, Animal; Benzazepines; Brain; Cats; Cer

1969
Observations on heroin and methadone withdrawal in the newborn.
    Pediatrics, 1971, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Apgar Score; Birth Weight; Female; Heroin; Humans; Infant, Newborn; Infant, Newbo

1971
Whooping cough in Uganda.
    Scandinavian journal of infectious diseases, 1971, Volume: 3, Issue:1

    Topics: Age Factors; Autopsy; Bronchopneumonia; Child; Child, Preschool; Chlorpromazine; Female; Humans; Inf

1971
[Our experiences with Tegretol in the treatment of epilepsy].
    Neuropsihijatrija, 1971, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Drug Synergism; Epilepsy; Female; Headache; Humans; M

1971
[Acetonemic vomiting].
    Monatsschrift fur Kinderheilkunde, 1969, Volume: 117, Issue:11

    Topics: Abdomen, Acute; Acidosis; Brain Neoplasms; Child, Preschool; Diabetic Coma; Diagnosis, Differential;

1969
[Reserpine therapy of periodic vomiting and abdominal pain in children].
    Ceskoslovenska pediatrie, 1970, Volume: 25, Issue:4

    Topics: Abdomen; Age Factors; Child; Humans; Pain; Phenobarbital; Reserpine; Vomiting

1970
Acute chlordane poisoning. Clinical and chemical studies.
    Archives of environmental health, 1969, Volume: 18, Issue:2

    Topics: Adipose Tissue; Alkaline Phosphatase; Aspartate Aminotransferases; Body Temperature; Child, Preschoo

1969