Page last updated: 2024-11-02

phenobarbital and Vitamin B 12 Deficiency

phenobarbital has been researched along with Vitamin B 12 Deficiency in 4 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Vitamin B 12 Deficiency: A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schwaninger, M1
Ringleb, P1
Winter, R1
Kohl, B1
Fiehn, W1
Rieser, PA1
Walter-Sack, I1
Reynolds, EH2
Chanarin, I1
Milner, G1
Matthews, DM2
Cramond, WA1
Hallpike, JF1
Phillips, BM1

Other Studies

4 other studies available for phenobarbital and Vitamin B 12 Deficiency

ArticleYear
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment.
    Epilepsia, 1999, Volume: 40, Issue:3

    Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epi

1999
Anticonvulsant therapy, folic acid and vitamin B12 metabolism and mental symptoms.
    Epilepsia, 1966, Volume: 7, Issue:4

    Topics: Adult; Anemia, Macrocytic; Female; Folic Acid Deficiency; Humans; Male; Mental Disorders; Middle Age

1966
Organic psychosis.
    British medical journal, 1968, Nov-30, Volume: 4, Issue:5630

    Topics: Adolescent; Adult; Aged; Barbiturates; Brain Neoplasms; Bronchopneumonia; Carbon Monoxide Poisoning;

1968
Reversible absorptive defects in anticonvulsant megaloblastic anaemia.
    Journal of clinical pathology, 1965, Volume: 18, Issue:5

    Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Blood; Female; FIGLU Test; Folic Acid Deficiency; Humans

1965