Page last updated: 2024-11-02

phenobarbital and Vitamin A Deficiency

phenobarbital has been researched along with Vitamin A Deficiency in 5 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Vitamin A Deficiency: A nutritional condition produced by a deficiency of VITAMIN A in the diet, characterized by NIGHT BLINDNESS and other ocular manifestations such as dryness of the conjunctiva and later of the cornea (XEROPHTHALMIA). Vitamin A deficiency is a very common problem worldwide, particularly in developing countries as a consequence of famine or shortages of vitamin A-rich foods. In the United States it is found among the urban poor, the elderly, alcoholics, and patients with malabsorption. (From Cecil Textbook of Medicine, 19th ed, p1179)

Research Excerpts

ExcerptRelevanceReference
"This study was undertaken to investigate the influence of dietary vitamin A deficiency and type of diet on tetrachlorodibenzo-p-dioxin (TCDD)- and phenobarbital-induced liver tumor promotion in rats."7.68Modulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin and phenobarbital-induced promotion of hepatocarcinogenesis in rats by the type of diet and vitamin A deficiency. ( Ahlborg, UG; Busk, L; Flodström, S; Kronevi, T, 1991)
"This study was undertaken to investigate the influence of dietary vitamin A deficiency and type of diet on tetrachlorodibenzo-p-dioxin (TCDD)- and phenobarbital-induced liver tumor promotion in rats."3.68Modulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin and phenobarbital-induced promotion of hepatocarcinogenesis in rats by the type of diet and vitamin A deficiency. ( Ahlborg, UG; Busk, L; Flodström, S; Kronevi, T, 1991)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chapman, KM1
Prabhudesai, M1
Erdman, JW1
Nurmagambetov, TZh1
Amirov, BB1
Kuanysheva, TK1
Sharmanov, TSh1
Flodström, S1
Busk, L1
Kronevi, T1
Ahlborg, UG1
Leo, MA1
Lowe, N1
Lieber, CS1
Campbell, TC1
Hayes, JR1

Reviews

1 review available for phenobarbital and Vitamin A Deficiency

ArticleYear
Role of nutrition in the drug-metabolizing enzyme system.
    Pharmacological reviews, 1974, Volume: 26, Issue:3

    Topics: Ascorbic Acid Deficiency; Calcium; Carbohydrates; Carcinogens; Catalysis; Chemical and Drug Induced

1974

Other Studies

4 other studies available for phenobarbital and Vitamin A Deficiency

ArticleYear
Effects of acute ethanol doses or dietary phenobarbitol with carbon tetrachloride exposure on vitamin A status of rats.
    Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:3

    Topics: Alcoholic Intoxication; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Inj

1993
[The induction of the monooxygenase system and the incorporation of the radioactive label from 2-14C-lysine into the liver microsome fraction of rats exposed to phenobarbital against a background of deficiencies in lysine, methionine, threonine and vitami
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 111, Issue:3

    Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Ascorbic Acid Deficiency; Avitamin

1991
Modulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin and phenobarbital-induced promotion of hepatocarcinogenesis in rats by the type of diet and vitamin A deficiency.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1991, Volume: 16, Issue:2

    Topics: Animals; Body Weight; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Diet; Female; Liver;

1991
Interaction of drugs and retinol.
    Biochemical pharmacology, 1986, Nov-15, Volume: 35, Issue:22

    Topics: Animals; Drug Interactions; Ethanol; Hydroxylation; In Vitro Techniques; Kinetics; Lung Neoplasms; M

1986