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phenobarbital and Urinary Tract Diseases

phenobarbital has been researched along with Urinary Tract Diseases in 4 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
"In phenobarbital-pretreated rats, MMPS administration had little effect on any renal functional parameter measured or urological morphology."1.28Role of para-hydroxylation in phensuximide-induced urotoxicity in the Fischer 344 rat. ( Anestis, DK; Beers, KW; Brown, PI; Hubbard, JL; Nicoll, DW; Rankin, GO; Shih, HC, 1992)
"Phenobarbital pretreatment had only minor effects on ESX- or MSX-induced renal effects, with no significant morphological changes detected between treated and pair-fed control groups."1.28Acute effects of the antiepileptic succinimides on the urinary tract and potentiation of phensuximide-induced urotoxicity by phenobarbital. ( Brown, PI; Nicoll, DW; Rankin, GO; Teets, VJ, 1990)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WANSEL, H1
HOYT, HS1
Rankin, GO2
Beers, KW1
Nicoll, DW2
Anestis, DK1
Shih, HC1
Brown, PI2
Hubbard, JL1
Teets, VJ1

Other Studies

4 other studies available for phenobarbital and Urinary Tract Diseases

ArticleYear
[SPASMO-DOLVIRAN OF THE "BAYER" LEVERKUSEN FIRM. TEST IN PRACTICE].
    Deutsches medizinisches Journal, 1964, Jun-20, Volume: 15

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Caffeine; Codeine; Drug Therapy; Gallbladder Dis

1964
Stress incontinence due to phenobarbital.
    The Urologic and cutaneous review, 1949, Volume: 53, Issue:7

    Topics: Autonomic Nervous System Diseases; Barbital; Barbiturates; Phenobarbital; Urinary Incontinence; Urin

1949
Role of para-hydroxylation in phensuximide-induced urotoxicity in the Fischer 344 rat.
    Toxicology, 1992, Volume: 74, Issue:1

    Topics: Animals; Biotransformation; Blood Urea Nitrogen; Drinking; Eating; Hematuria; Hydroxylation; Kidney;

1992
Acute effects of the antiepileptic succinimides on the urinary tract and potentiation of phensuximide-induced urotoxicity by phenobarbital.
    Journal of applied toxicology : JAT, 1990, Volume: 10, Issue:3

    Topics: Animals; Anticonvulsants; Drug Synergism; Ethosuximide; Kidney Diseases; Male; Phenobarbital; Rats;

1990