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phenobarbital and Thrombophilia

phenobarbital has been researched along with Thrombophilia in 1 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Thrombophilia: A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.

Research Excerpts

ExcerptRelevanceReference
"Medroxyprogesterone acetate (MPA) is a drug commonly used in endocrine therapy for advanced breast cancer, although it is known to cause thrombosis as a serious side effect."1.32Metabolism of medroxyprogesterone acetate (MPA) via CYP enzymes in vitro and effect of MPA on bleeding time in female rats in dependence on CYP activity in vivo. ( Chiba, K; Hosokawa, M; Kobayashi, K; Mimura, N; Nakamura, Y; Shimada, N, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mimura, N1
Kobayashi, K1
Nakamura, Y1
Shimada, N1
Hosokawa, M1
Chiba, K1

Other Studies

1 other study available for phenobarbital and Thrombophilia

ArticleYear
Metabolism of medroxyprogesterone acetate (MPA) via CYP enzymes in vitro and effect of MPA on bleeding time in female rats in dependence on CYP activity in vivo.
    Life sciences, 2003, Nov-07, Volume: 73, Issue:25

    Topics: Animals; Bleeding Time; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Disease Models, Anim

2003