phenobarbital has been researched along with Thrombocytopenia in 11 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Thrombocytopenia: A subnormal level of BLOOD PLATELETS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report on a patient with epilepsy who developed leukopenia and thrombocytopenia during phenobarbital/lamotrigine treatment." | 7.76 | Phenobarbital/Lamotrigine coadministration-induced blood dyscrasia in a patient with epilepsy. ( Calabrò, G; De Sarro, G; Gallelli, L; Siniscalchi, A; Tolotta, GA, 2010) |
| "To report on a patient with epilepsy who developed leukopenia and thrombocytopenia during phenobarbital/lamotrigine treatment." | 3.76 | Phenobarbital/Lamotrigine coadministration-induced blood dyscrasia in a patient with epilepsy. ( Calabrò, G; De Sarro, G; Gallelli, L; Siniscalchi, A; Tolotta, GA, 2010) |
| " Sensitivity to phenobarbital and related anticonvulsants may induce life-threatening leukopenia, thrombocytopenia, and anemia in dogs." | 3.70 | Neutropenia and thrombocytopenia in three dogs treated with anticonvulsants. ( Calvert, C; Jacobs, G; Kaufman, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Siniscalchi, A | 1 |
| Gallelli, L | 1 |
| Calabrò, G | 1 |
| Tolotta, GA | 1 |
| De Sarro, G | 1 |
| SAFRONOV, EI | 1 |
| RYDER, RJ | 1 |
| Morozov, GV | 1 |
| Semenova, NV | 1 |
| Slastenko, OA | 1 |
| Mishchenko, AL | 1 |
| Smits-Wintjens, VE | 1 |
| Walther, FJ | 1 |
| Lopriore, E | 1 |
| Khoutorsky, A | 1 |
| Bruchim, Y | 1 |
| Jacobs, G | 1 |
| Calvert, C | 1 |
| Kaufman, A | 1 |
| Ferguson, PW | 1 |
| Anderson, JH | 1 |
| Krieger, RI | 1 |
| Pochedly, C | 1 |
| Ente, G | 1 |
| Gassel, WD | 1 |
| Schneider, D | 1 |
| Parker, WA | 1 |
2 reviews available for phenobarbital and Thrombocytopenia
| Article | Year |
|---|---|
Rhesus haemolytic disease of the newborn: Postnatal management, associated morbidity and long-term outcome.
Topics: Albumins; Anemia, Neonatal; Cholestasis; Fluid Therapy; Humans; Hydrops Fetalis; Hyperbilirubinemia, | 2008 |
Adverse hematologic effects of drugs.
Topics: Anemia, Hemolytic; Anemia, Macrocytic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents | 1972 |
9 other studies available for phenobarbital and Thrombocytopenia
| Article | Year |
|---|---|
Phenobarbital/Lamotrigine coadministration-induced blood dyscrasia in a patient with epilepsy.
Topics: Adult; Anticonvulsants; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamo | 2010 |
[A CASE OF RADIATION SICKNESS CAUSED BY INTERNAL IRRADIATION].
Topics: 17-Ketosteroids; Blood Cell Count; Blood Pressure; Blood Protein Electrophoresis; Blood Sedimentatio | 1964 |
HAEMORRHAGE ASSOCIATED WITH THROMBOCYTOPENIA IN MEGALOBLASTIC ANAEMIA.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Blood Platelet Disorders; Drug Therapy; Epilepsy; | 1964 |
[Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy].
Topics: Adolescent; Adult; Barbiturates; Carbamazepine; Epilepsy; Humans; In Vitro Techniques; Lamotrigine; | 2004 |
Transient leucopenia, thrombocytopenia and anaemia associated with severe acute phenobarbital intoxication in a dog.
Topics: Anemia; Animals; Anti-Anxiety Agents; Dog Diseases; Dogs; Leukopenia; Male; Phenobarbital; Thrombocy | 2008 |
Neutropenia and thrombocytopenia in three dogs treated with anticonvulsants.
Topics: Anemia; Animals; Anticonvulsants; Bacteremia; Blood Cell Count; Dog Diseases; Dogs; Female; Male; Ne | 1998 |
Secondary thrombocytopenia following phenobarbital treatments in a rhesus monkey (Macaca mulatta).
Topics: Animals; Blood Cell Count; Blood Platelets; Haplorhini; Macaca; Macaca mulatta; Male; Monkey Disease | 1979 |
[Acute drug allergic thrombocytopenia caused by antazoline].
Topics: Aged; Ajmaline; Aniline Compounds; Arrhythmias, Cardiac; Benzyl Compounds; Bone Marrow Examination; | 1974 |
Letter: Primidone thrombocytopenia.
Topics: Adult; Female; Humans; Phenobarbital; Primidone; Seizures; Thrombocytopenia | 1974 |