Page last updated: 2024-11-02

phenobarbital and Syndrome

phenobarbital has been researched along with Syndrome in 81 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"A case of propofol infusion syndrome in a patient with respiratory failure and sepsis is reported."8.85Propofol infusion syndrome: case report and literature review. ( Chen, J; Cohen, N; Nadkarni, A; Orsini, J, 2009)
"To report a case of type 1 diabetes mellitus (T1DM) in a child with phenobarbital hypersensitivity syndrome with an emphasis on the clinical presentation, diagnostic modalities and treatment options."7.74Type 1 diabetes mellitus in a child with phenobarbital hypersensitivity syndrome. ( Fu, JF; Liang, L; Zou, CC, 2008)
"A 68-year-old man was diagnosed as drug-induced hypersensitivity syndrome (DIHS) with erythema and liver dysfunction three weeks after an administration of phenobarbital."7.73[Limbic encephalitis associated with drug-induced hypersensitivity syndrome due to phenobarbital--a case report]. ( Chiba, A; Ito, T; Ooishi, C; Sakuma, K; Sakuta, M; Shiohara, T, 2005)
"An 11-month-old boy with multiple surface anomalies and respiratory distress due to upper airway narrowing developed generalized tonic seizures coinciding with apnea."7.73[High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome]. ( Hayashi, T; Horio, K; Kubota, M; Mimaki, M; Tomita, S, 2006)
"To report a case of status epilepticus in a patient with anticonvulsant hypersensitivity syndrome (AHS) that was controlled successfully using continuous intravenous infusion diazepam."7.68Diazepam by continuous intravenous infusion for status epilepticus in anticonvulsant hypersensitivity syndrome. ( Bertz, RJ; Howrie, DL, 1993)
"Three families are described in which each of the mothers took trimethadione during pregnancy."7.65The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975)
" Apart from the hyperbilirubinemia (which comprised around 50% of conjugated bilirubin), usual hepatic function tests were normal."7.65Chronic hyperbilirubinemia associated with hepatic uptake and storage impairment. A new syndrome resembling that of the mutant Southdown sheep. ( Berthelot, P; Dhumeaux, D, 1975)
"The case of a two-year-old girl with generalized histiocytosis, probably induced by phenobarbital, is reported."6.38A case of hypersensitivity syndrome resembling Langerhans cell histiocytosis during phenobarbital prophylaxis for convulsion. ( Kawamura, N; Mino, M; Miyake, M; Motoyama, T; Nagata, T; Oguni, T; Yamasiro, K; Yoden, A; Yoshikawa, K, 1992)
" High-dose topiramate combined with high-dose lidocaine infusion or high-dose phenobarbital in the acute stage might be an effective treatment option for children with AERRPS."5.35Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures. ( Hsia, SH; Lin, JJ; Lin, KL; Wang, HS; Wu, CT, 2009)
" Group 1 (n = 48), group 2 (n = 29), and group 3 (n = 18) received phenobarbital at the dosage of 5 mg/kg/day for at least 5 days, less than 5 mg/kg/day or less than 5 days, and no premedication, respectively."5.32The effect of phenobarbital on the accuracy of technetium-99m diisopropyl iminodiacetic acid hepatobiliary scintigraphy in differentiating biliary atresia from neonatal hepatitis syndrome. ( Charearnrad, P; Chongsrisawat, V; Poovorawan, Y; Tepmongkol, S, 2003)
" In the first experiment, the lower end of the malformation dose-response curves for diphenylhydantoin (DPH), trimethadione (TMD) and phenobarbital (PB) were established."5.27Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring. ( Vorhees, CV, 1983)
"A case of propofol infusion syndrome in a patient with respiratory failure and sepsis is reported."4.85Propofol infusion syndrome: case report and literature review. ( Chen, J; Cohen, N; Nadkarni, A; Orsini, J, 2009)
"The antiepileptic drug hypersensitivity syndrome (AHS) is an adverse drug reaction associated with the aromatic antiepileptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), and primidone."4.80Antiepileptic drug hypersensitivity syndrome. ( Schlienger, RG; Shear, NH, 1998)
"Anticonvulsant hypersensitivity syndrome (AHS) is an uncommon but potentially fatal adverse effect that can occur from exposure to phenytoin, carbamazepine, or phenobarbital."4.79Anticonvulsant hypersensitivity syndrome. ( Miller, MB; Morkunas, AR, 1997)
" We describe a patient with phenobarbital-induced hypersensitivity syndrome who revealed syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with limbic encephalitis during the course of the disease."3.74Syndrome of inappropriate secretion of antidiuretic hormone associated with limbic encephalitis in a patient with drug-induced hypersensitivity syndrome. ( Fukuhara, M; Kano, Y; Sakuma, K; Shiohara, T, 2008)
"To report a case of type 1 diabetes mellitus (T1DM) in a child with phenobarbital hypersensitivity syndrome with an emphasis on the clinical presentation, diagnostic modalities and treatment options."3.74Type 1 diabetes mellitus in a child with phenobarbital hypersensitivity syndrome. ( Fu, JF; Liang, L; Zou, CC, 2008)
"A 68-year-old man was diagnosed as drug-induced hypersensitivity syndrome (DIHS) with erythema and liver dysfunction three weeks after an administration of phenobarbital."3.73[Limbic encephalitis associated with drug-induced hypersensitivity syndrome due to phenobarbital--a case report]. ( Chiba, A; Ito, T; Ooishi, C; Sakuma, K; Sakuta, M; Shiohara, T, 2005)
"An 11-month-old boy with multiple surface anomalies and respiratory distress due to upper airway narrowing developed generalized tonic seizures coinciding with apnea."3.73[High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome]. ( Hayashi, T; Horio, K; Kubota, M; Mimaki, M; Tomita, S, 2006)
"We describe the case of a patient in whom anticonvulsant hypersensitivity syndrome developed during treatment with phenytoin and progressed when therapy was changed to phenobarbital."3.72Anticonvulsant hypersensitivity syndrome: treatment with corticosteroids and intravenous immunoglobulin. ( Finch, CK; Jones, R; Mostella, J; Pieroni, R, 2004)
"A full-term baby was born to an epileptic mother treated with two anti-epileptic drugs, sodium valproate and phenobarbital, throughout the pregnancy."3.70[A case of fetal valproate syndrome with intractable wheezing due to submucosal tumor below the vocal cord]. ( Adachi, M; Ai, Y; Maeda, E, 1999)
" We report a patient with severe phenobarbital-induced anticonvulsant hypersensitivity syndrome in whom a fulminant haemophagocytic syndrome was associated with HHV6 infection."3.69Human herpesvirus 6 infection associated with anticonvulsant hypersensitivity syndrome and reactive haemophagocytic syndrome. ( Aslangul, E; Belaich, S; Bouscarat, F; Crickx, B; Descamps, D; Descamps, V; Grange, MJ; Grossin, M; Laglenne, S; Navratil, E; Saraux, JL; Veber, B, 1997)
"Anticonvulsant hypersensitivity syndrome is a potentially fatal drug reaction with cutaneous and systemic reactions (incidence, one in 1000 to one in 10,000 exposures) to the arene oxide-producing anticonvulsants--phenytoin, carbamazepine, and phenobarbital sodium."3.69Anticonvulsant hypersensitivity syndrome. ( Muglia, JJ; Vittorio, CC, 1995)
"To report a case of status epilepticus in a patient with anticonvulsant hypersensitivity syndrome (AHS) that was controlled successfully using continuous intravenous infusion diazepam."3.68Diazepam by continuous intravenous infusion for status epilepticus in anticonvulsant hypersensitivity syndrome. ( Bertz, RJ; Howrie, DL, 1993)
"An oral tolerance test using a 25-mg dose of ursodeoxycholic acid was carried out in 46 patients with constitutional hyperbilirubinemias: 26 with Gilbert's syndrome, 9 with Dubin-Johnson syndrome, 7 with Rotor Syndrome, 3 with constitutional indocyanine green intolerance, and 1 with Crigler-Najjar syndrome type II; they were compared with 14 healthy control subjects."3.66Ursodeoxycholic acid oral tolerance test in patients with constitutional hyperbilirubinemias and effect of phenobarbital. ( Iida, S; Makino, I; Ohkubo, H; Okuda, K, 1981)
"Three families are described in which each of the mothers took trimethadione during pregnancy."3.65The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975)
"The therapeutics results with the use of different drugs (diazepam, nitrazepam, clonazepam, diphenylhydantoin, barbiturates--phenobarbital and primidone--, sodium dipropylacetate and ACTH) in twenty-nine patients with Lennox--Gastaut syndrome are carefully analysed."3.65[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome]. ( Lison, MP; Speciali, GG, 1977)
" Apart from the hyperbilirubinemia (which comprised around 50% of conjugated bilirubin), usual hepatic function tests were normal."3.65Chronic hyperbilirubinemia associated with hepatic uptake and storage impairment. A new syndrome resembling that of the mutant Southdown sheep. ( Berthelot, P; Dhumeaux, D, 1975)
"Vomiting was severe enough in all patients to cause dehydration requiring hospitalization for intravenous rehydration."2.74Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate. ( Amakata, K; Fujii, Y; Hikita, T; Kaga, F; Kaneko, S; Kodama, H; Nakamoto, N; Ogita, K; Yanagawa, Y, 2009)
"The case of a two-year-old girl with generalized histiocytosis, probably induced by phenobarbital, is reported."2.38A case of hypersensitivity syndrome resembling Langerhans cell histiocytosis during phenobarbital prophylaxis for convulsion. ( Kawamura, N; Mino, M; Miyake, M; Motoyama, T; Nagata, T; Oguni, T; Yamasiro, K; Yoden, A; Yoshikawa, K, 1992)
"All patients suffered from seizures during wakefulness."1.36Benign infantile focal epilepsy with midline spikes and waves during sleep: a new epileptic syndrome or a variant of benign focal epilepsy? ( Caraballo, R; Cersósimo, R; Flesler, S; Sakr, D, 2010)
" High-dose topiramate combined with high-dose lidocaine infusion or high-dose phenobarbital in the acute stage might be an effective treatment option for children with AERRPS."1.35Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures. ( Hsia, SH; Lin, JJ; Lin, KL; Wang, HS; Wu, CT, 2009)
"This syndrome is accompanied by fever, rash, lymphadenopathy, eosinophilia and affects parenchymal organs."1.32[Anticonvulsant hypersensitivity syndrome]. ( Papp, Z; Török, L, 2004)
" Group 1 (n = 48), group 2 (n = 29), and group 3 (n = 18) received phenobarbital at the dosage of 5 mg/kg/day for at least 5 days, less than 5 mg/kg/day or less than 5 days, and no premedication, respectively."1.32The effect of phenobarbital on the accuracy of technetium-99m diisopropyl iminodiacetic acid hepatobiliary scintigraphy in differentiating biliary atresia from neonatal hepatitis syndrome. ( Charearnrad, P; Chongsrisawat, V; Poovorawan, Y; Tepmongkol, S, 2003)
"Orthostatic tremor is an unusual kind of potentially disabiling tremor appearing immediately when standing."1.30["Primary" orthostatic tremor. 10 clinical electrophysiologic observations]. ( Cassim, F; Destée, A; Guieu, JD; Mastain, B, 1998)
" We consider his cerebellar symptoms and peripheral neuropathy could be attributable to the long-term use of multiple anticonvulsants, i."1.29[Lennox syndrome associated with severe cerebellar dysfunction and peripheral neuropathy]. ( Kubota, M; Nagata, J, 1993)
"The syndrome is characterized by a clinical ictal triad of nocturnal seizures, tonic deviation of the eyes, and vomiting."1.28Benign nocturnal childhood occipital epilepsy: a new syndrome with nocturnal seizures, tonic deviation of the eyes, and vomiting. ( Panayiotopoulos, CP, 1989)
" In the first experiment, the lower end of the malformation dose-response curves for diphenylhydantoin (DPH), trimethadione (TMD) and phenobarbital (PB) were established."1.27Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring. ( Vorhees, CV, 1983)
"Type I (clonic) HPNS seizures are not associated with any additional changes in heart rate."1.26Changes in heart rate associated with high-pressure convulsions in rodents. ( Beaver, RW; Brauer, RW; Fuquay, J, 1979)

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-199043 (53.09)18.7374
1990's17 (20.99)18.2507
2000's18 (22.22)29.6817
2010's3 (3.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Imataka, G1
Noguchi, M1
Tsukada, K1
Takahashi, T1
Yamanouchi, H1
Arisaka, O1
Song, RB1
Glass, EN1
Kent, M1
Castro, FA1
deLahunta, A1
Hikita, T1
Kodama, H1
Nakamoto, N1
Kaga, F1
Amakata, K1
Ogita, K1
Kaneko, S1
Fujii, Y1
Yanagawa, Y1
Lin, JJ1
Lin, KL1
Wang, HS1
Hsia, SH1
Wu, CT1
Taillia, H1
Alla, P1
Fournier, B1
Bounolleau, P1
Ouologem, M1
Ricard, D1
Sallansonnet-Froment, M1
de Greslan, T1
Renard, JL1
Orsini, J1
Nadkarni, A1
Chen, J1
Cohen, N1
Flesler, S1
Sakr, D1
Cersósimo, R1
Caraballo, R1
Tanaka, M2
Inoue, Y2
Toomes, M1
Maleck, WH1
Koetter, KP1
Petroianu, GA1
Charearnrad, P1
Chongsrisawat, V1
Tepmongkol, S1
Poovorawan, Y1
MCGEACHY, TE1
BLOOMER, WE1
EMICH, R2
ZARAFONETIS, CJ1
MOLTHAN, L1
Schennetten, F1
Ehrhardt, R1
Lubeck, I1
TOPP, G1
ERBELOWA, A1
ZAWADZKA, M1
DANIEL, W1
PROCKL, K1
CHAO, D1
DAVIS, SD1
FULTON, WH1
DYKEN, PR1
URBANO, L1
Mostella, J1
Pieroni, R1
Jones, R1
Finch, CK1
Papp, Z1
Török, L1
Ito, T1
Ooishi, C1
Chiba, A1
Sakuta, M1
Sakuma, K2
Shiohara, T2
Costa, E1
Vieira, E1
Dos Santos, R1
Hayashi, T1
Kubota, M2
Mimaki, M1
Tomita, S1
Horio, K1
Kano, Y1
Fukuhara, M1
Zou, CC1
Liang, L1
Fu, JF1
Vorhees, CV1
Kato, H1
Domenici, R1
Giovannucci Uzielli, ML1
Castelli, S1
Guliamov, MG1
García Nieto, V1
López Mendoza, S1
Ortigosa, L1
Rodríguez, I1
Ohkubo, H1
Okuda, K1
Iida, S1
Makino, I1
Dockter, G1
Müller, J1
Vittorio, CC1
Muglia, JJ1
Nagata, J1
Bertz, RJ1
Howrie, DL1
Morkunas, AR1
Miller, MB1
Descamps, V1
Bouscarat, F1
Laglenne, S1
Aslangul, E1
Veber, B1
Descamps, D1
Saraux, JL1
Grange, MJ1
Grossin, M1
Navratil, E1
Crickx, B1
Belaich, S1
Aagenaes, O1
Mastain, B1
Cassim, F1
Guieu, JD1
Destée, A1
Marciani, MG1
Spanedda, F1
Placidi, F1
Bassetti, MA1
Romigi, A1
Mattia, D1
Schlienger, RG1
Shear, NH1
van Putten, MJ1
Bosman-Vermeeren, JM1
Brouwer, OF1
Adachi, M1
Ai, Y1
Maeda, E1
Bessmertny, O1
Hatton, RC1
Gonzalez-Peralta, RP1
Lachgar, T1
Touil, Y1
Ho, YY1
Yang, H1
Klepper, J1
Fischbarg, J1
Wang, D1
De Vivo, DC1
Zackai, EH1
Mellman, WJ1
Neiderer, B1
Hanson, JW2
Smith, DW1
Drobný, M1
Wolfová, E1
Adamkov, J1
Bevilaqua, L1
Fundárek, J1
Pithová, B1
Knéslová, L1
Speciali, GG1
Lison, MP1
Brun, A1
Gilboa, M1
Meeuwisse, GW1
Nordgren, H1
Baudouy, P1
Andreassian, B1
Attuel, P1
Greze, M1
Soulie, J1
Fruchaud, J1
Kugoh, T1
Hosokawa, K1
Oleĭnik, AN1
Botez, MI1
Peyronnard, JM1
Bérubé, L1
Labrecque, R1
Edel'shteĭn, EA1
Bondarenko, ES1
Mumladze, TA1
Beaver, RW1
Brauer, RW1
Fuquay, J1
Horváth, T1
Gógl, A1
Simon, K1
Stadler, HE1
Beaufils, F1
Aujard, Y1
Huault, G1
Chadwick, D1
Reynolds, EH1
Marsden, CD1
Arrowsmith, WA1
Payne, RB1
Littlewood, JM1
Dhumeaux, D1
Berthelot, P1
Van Buren, JM1
Marsan, CA1
Mutsuga, N1
Rodin, EA1
Hesse, S1
Berbis, P1
Lafforgue, P1
Acquaviva, PC1
Pastor, MJ1
Privat, Y1
Dodman, NH1
Miczek, KA1
Knowles, K1
Thalhammer, JG1
Shuster, L1
Nagata, T1
Kawamura, N1
Motoyama, T1
Miyake, M1
Yoden, A1
Yoshikawa, K1
Oguni, T1
Yamasiro, K1
Mino, M1
Dubowitz, LM1
Bouza, H1
Hird, MF1
Jaeken, J1
Yerby, MS1
Leavitt, A1
Erickson, DM1
McCormick, KB1
Loewenson, RB1
Sells, CJ1
Benedetti, TJ1
Kleier, RS1
Breneman, DL1
Boiko, S1
Panayiotopoulos, CP1
Pett, S1
Mowat, AP1
Parsonage, M1
Fink, RD1
Knott, DH1
Beard, JD1
Hepner, GW1
Vesell, ES1
Ideo, G1
Del Ninno, E1
De Franchis, R1
Bitto, T1
Colombo, M1
Blaschke, TF1
Berk, PD1
Scharschmidt, BF1
Guyther, JR1
Vergalla, JM1
Waggoner, JG1

Reviews

10 reviews available for phenobarbital and Syndrome

ArticleYear
Propofol infusion syndrome: case report and literature review.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009, May-15, Volume: 66, Issue:10

    Topics: Adult; Anesthetics, Intravenous; Drug Administration Schedule; Exanthema; Female; Hepatomegaly; Huma

2009
[Epilepsy with GTCs on awakening].
    Ryoikibetsu shokogun shirizu, 2002, Issue:37 Pt 6

    Topics: Adolescent; Adult; Child; Diagnosis, Differential; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Pr

2002
[Other generalized epilepsies not defined above].
    Ryoikibetsu shokogun shirizu, 2002, Issue:37 Pt 6

    Topics: Diagnosis, Differential; Epilepsy, Generalized; Humans; Phenobarbital; Prognosis; Syndrome; Valproic

2002
Anticonvulsant hypersensitivity syndrome.
    Critical care clinics, 1997, Volume: 13, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Drug Interactions; Felbamate; Humans; Phenoba

1997
Hereditary cholestasis with lymphoedema (Aagenaes syndrome, cholestasis-lymphoedema syndrome). New cases and follow-up from infancy to adult age.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Child; Child, Preschool; Cholestasis; Consanguinity; Female; Follow-Up Studies; G

1998
Antiepileptic drug hypersensitivity syndrome.
    Epilepsia, 1998, Volume: 39 Suppl 7

    Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Diagnosis, Differential; D

1998
[Central apnea in newborns].
    Nederlands tijdschrift voor geneeskunde, 1999, Feb-27, Volume: 143, Issue:9

    Topics: Acetazolamide; Anticonvulsants; Apnea; Arnold-Chiari Malformation; Diagnosis, Differential; DiGeorge

1999
[Effect of phenobarbital on the intrahepatic metabolism of bilirubin].
    Klinicheskaia meditsina, 1978, Volume: 56, Issue:2

    Topics: Animals; Bile; Bilirubin; Biological Transport, Active; Cytoplasm; Drug Evaluation; Drug Interaction

1978
[Acne and enthesiopathy during anti-epileptic treatment].
    Annales de dermatologie et de venereologie, 1992, Volume: 119, Issue:9

    Topics: Acne Vulgaris; Adult; Arthritis; Humans; Male; Osteitis; Phenobarbital; Sacroiliac Joint; Sternocost

1992
A case of hypersensitivity syndrome resembling Langerhans cell histiocytosis during phenobarbital prophylaxis for convulsion.
    Japanese journal of clinical oncology, 1992, Volume: 22, Issue:6

    Topics: Child, Preschool; Diagnosis, Differential; Drug Eruptions; Eosinophils; Epilepsy; Female; Histiocyte

1992

Trials

3 trials available for phenobarbital and Syndrome

ArticleYear
Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate.
    Brain & development, 2009, Volume: 31, Issue:6

    Topics: Anticonvulsants; Child; Child, Preschool; Dehydration; Dose-Response Relationship, Drug; Drug Admini

2009
[Experience with the use of new Bulgarian psychotropic drugs].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:11

    Topics: Adolescent; Adult; Aminopyrine; Aminoquinolines; Child; Clinical Trials as Topic; Depression; Dipyro

1982
[Effectiveness of fenalgin SPOFA in lumboischiadic syndrome (author's transl)].
    Bratislavske lekarske listy, 1979, Volume: 71, Issue:4

    Topics: Acetaminophen; Adult; Aspirin; Back Pain; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxy

1979

Other Studies

68 other studies available for phenobarbital and Syndrome

ArticleYear
Partial epilepsy and developmental delay in infant with ring chromosome 14.
    Genetic counseling (Geneva, Switzerland), 2013, Volume: 24, Issue:1

    Topics: Anticonvulsants; Benzodiazepines; Child, Preschool; Chromosome Disorders; Chromosomes, Human, Pair 1

2013
Magnetic resonance imaging and computed tomography findings of Dyke-Davidoff-Masson-like syndrome in a cat.
    Australian veterinary journal, 2015, Volume: 93, Issue:10

    Topics: Animals; Anticonvulsants; Brain; Brain Diseases; Brain Injuries; Cat Diseases; Cats; Female; Magneti

2015
Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures.
    Brain & development, 2009, Volume: 31, Issue:8

    Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography

2009
[Anticonvulsant hypersensitivity syndrome and lamotrigine-associated anticonvulsant hypersensitivity syndrome].
    Revue neurologique, 2009, Volume: 165, Issue:10

    Topics: Adult; Aged; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Drug Hypersensitivity; Eosinophilia;

2009
Benign infantile focal epilepsy with midline spikes and waves during sleep: a new epileptic syndrome or a variant of benign focal epilepsy?
    Epileptic disorders : international epilepsy journal with videotape, 2010, Volume: 12, Issue:3

    Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child, Preschool; Drug Therapy, Combination; Electroen

2010
Out-of-hospital management of benzodiazepine-resistant status epilepticus in a child with Wolf-Hirschhorn syndrome.
    Epileptic disorders : international epilepsy journal with videotape, 2003, Volume: 5, Issue:2

    Topics: Abnormalities, Multiple; Anticonvulsants; Apnea; Child; Chromosome Deletion; Chromosomes, Human, Pai

2003
The effect of phenobarbital on the accuracy of technetium-99m diisopropyl iminodiacetic acid hepatobiliary scintigraphy in differentiating biliary atresia from neonatal hepatitis syndrome.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2003, Volume: 86 Suppl 2

    Topics: Biliary Atresia; Excitatory Amino Acid Antagonists; Female; Hepatitis; Humans; Infant; Infant, Newbo

2003
The phenobarbital sensitivity syndrome.
    The American journal of medicine, 1953, Volume: 14, Issue:5

    Topics: Barbiturates; Humans; Phenobarbital; Syndrome

1953
[Treatment of climacteric disorders].
    Wiener medizinische Wochenschrift (1946), 1956, Oct-06, Volume: 106, Issue:40

    Topics: Castor Oil; Climacteric; Female; Humans; Nitrites; Phenobarbital; Syndrome; Theophylline

1956
[Treatment of climacteric disorders].
    Wiener medizinische Wochenschrift (1946), 1956, Oct-06, Volume: 106, Issue:40

    Topics: Castor Oil; Climacteric; Female; Humans; Nitrites; Phenobarbital; Syndrome; Theophylline

1956
[Treatment of climacteric disorders].
    Wiener medizinische Wochenschrift (1946), 1956, Oct-06, Volume: 106, Issue:40

    Topics: Castor Oil; Climacteric; Female; Humans; Nitrites; Phenobarbital; Syndrome; Theophylline

1956
[Treatment of climacteric disorders].
    Wiener medizinische Wochenschrift (1946), 1956, Oct-06, Volume: 106, Issue:40

    Topics: Castor Oil; Climacteric; Female; Humans; Nitrites; Phenobarbital; Syndrome; Theophylline

1956
Apparent phenobarbital sensitivity syndrome from weight-reduction regimen; response to steroid hormone therapy.
    Pennsylvania medical journal (1928), 1957, Volume: 60, Issue:8

    Topics: Humans; Obesity; Phenobarbital; Steroids; Syndrome

1957
[Studies on an objective medical compensation of the orthotic syndrome].
    Schweizerische Zeitschrift fur Geschichte. Revue suisse d'histoire. Rivista storica svizzera, 1958, Volume: 10

    Topics: Cardiovascular Diseases; Humans; Neostigmine; Phenobarbital; Posture; Syndrome

1958
[Experiences in treatment of climacteric disorders with feminon and cesradyston].
    Medizinische Klinik, 1959, Feb-27, Volume: 54, Issue:9

    Topics: Alkaloids; Climacteric; Female; Humans; Irritants; Ovary; Phenobarbital; Plant Extracts; Syndrome

1959
[A contribution to the syndrome of toxic sensitization to luminal].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1960, Mar-14, Volume: 15

    Topics: Learning; Nervous System Physiological Phenomena; Phenobarbital; Syndrome

1960
[A contribution to the treatment of the climacteric syndrome].
    Wiener klinische Wochenschrift, 1963, May-03, Volume: 75

    Topics: Climacteric; Humans; Hydantoins; Phenobarbital; Syndrome

1963
CONVULSIVE EQUIVALENT SYNDROME OF CHILDHOOD.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: Acetazolamide; Adolescent; Anticonvulsants; Autonomic Nervous System Diseases; Child; Chlorpromazine

1964
NEUROLOGICAL SYNDROMES OF SYSTEMIC LUPUS ERYTHEMATOSUS.
    Neurology, 1964, Volume: 14

    Topics: Adolescent; Anticonvulsants; Autoimmune Diseases; Blood Proteins; Cerebral Cortex; Cerebrospinal Flu

1964
[Clinical experience in the treatment of asthmatic syndromes with dimethylbenzylpyridilethylenediamine associated with theophylline, ephedrine, and phenylethylmalonylurea].
    Gazzetta medica italiana, 1952, Volume: 111, Issue:3

    Topics: Asthma; Ephedrine; Humans; Phenobarbital; Syndrome; Theophylline

1952
Anticonvulsant hypersensitivity syndrome: treatment with corticosteroids and intravenous immunoglobulin.
    Southern medical journal, 2004, Volume: 97, Issue:3

    Topics: Adult; Anticonvulsants; Cross Reactions; Drug Hypersensitivity; Female; Glucocorticoids; Humans; Imm

2004
[Anticonvulsant hypersensitivity syndrome].
    Orvosi hetilap, 2004, Aug-08, Volume: 145, Issue:32

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug

2004
[Limbic encephalitis associated with drug-induced hypersensitivity syndrome due to phenobarbital--a case report].
    Rinsho shinkeigaku = Clinical neurology, 2005, Volume: 45, Issue:7

    Topics: Aged; Drug Hypersensitivity; Herpesvirus 6, Human; Humans; Limbic Encephalitis; Male; Phenobarbital;

2005
The polymorphism c.-3279T>G in the phenobarbital-responsive enhancer module of the bilirubin UDP-glucuronosyltransferase gene is associated with Gilbert syndrome.
    Clinical chemistry, 2005, Volume: 51, Issue:11

    Topics: Adolescent; Adult; Enhancer Elements, Genetic; Female; Gilbert Disease; Glucuronosyltransferase; Hum

2005
[High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome].
    No to hattatsu = Brain and development, 2006, Volume: 38, Issue:5

    Topics: Abnormalities, Multiple; Anticonvulsants; Apnea; Cough; Humans; Infant, Newborn; Male; Phenobarbital

2006
Syndrome of inappropriate secretion of antidiuretic hormone associated with limbic encephalitis in a patient with drug-induced hypersensitivity syndrome.
    Clinical and experimental dermatology, 2008, Volume: 33, Issue:3

    Topics: Acyclovir; Aged; Anticonvulsants; Antiviral Agents; Coma; Drug Hypersensitivity; Encephalitis; Epile

2008
Type 1 diabetes mellitus in a child with phenobarbital hypersensitivity syndrome.
    Journal of endocrinological investigation, 2008, Volume: 31, Issue:4

    Topics: Adrenal Cortex Hormones; Child, Preschool; Diabetes Mellitus, Type 1; Drug Hypersensitivity; Female;

2008
Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Developmental Disabilities; Dose-Response Re

1983
Antiepileptic drugs and psychiatric disorders: mechanism involved in manifestation of psychic symptoms of high blood level of antiepileptics.
    Folia psychiatrica et neurologica japonica, 1983, Volume: 37, Issue:3

    Topics: Adult; Anticonvulsants; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Male; Mental D

1983
[Multiple-abnormalities syndrome with phenotypic characteristics falling within the lacrimo-auriculo-dento-digital syndrome].
    Minerva pediatrica, 1984, Oct-15, Volume: 36, Issue:19

    Topics: Abnormalities, Drug-Induced; Ear, External; Female; Growth Disorders; Hand Deformities, Congenital;

1984
[Absence of hypoplasia of fingernails and toenails and terminal phalanges of hands and feet (author's transl)].
    Anales espanoles de pediatria, 1980, Volume: 13, Issue:8

    Topics: Abnormalities, Multiple; Animals; Brain Diseases; Carbamazepine; Cats; Child, Preschool; Cysts; Deaf

1980
Ursodeoxycholic acid oral tolerance test in patients with constitutional hyperbilirubinemias and effect of phenobarbital.
    Gastroenterology, 1981, Volume: 81, Issue:1

    Topics: Administration, Oral; Adult; Deoxycholic Acid; Female; Gilbert Disease; Humans; Hyperbilirubinemia,

1981
[Familial recurring intrahepatic cholestasis of the Tygstrup-Summerskill-Walshe type].
    Monatsschrift fur Kinderheilkunde, 1980, Volume: 128, Issue:5

    Topics: Adult; Child, Preschool; Cholestasis; Cholestyramine Resin; Female; Humans; Liver; Male; Phenobarbit

1980
Anticonvulsant hypersensitivity syndrome.
    Archives of internal medicine, 1995, Nov-27, Volume: 155, Issue:21

    Topics: Adult; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Female; Fever; Humans; Lymphatic Disea

1995
[Lennox syndrome associated with severe cerebellar dysfunction and peripheral neuropathy].
    No to shinkei = Brain and nerve, 1993, Volume: 45, Issue:7

    Topics: Adult; Anticonvulsants; Brain; Cerebellar Ataxia; Drug Therapy, Combination; Epilepsy, Generalized;

1993
Diazepam by continuous intravenous infusion for status epilepticus in anticonvulsant hypersensitivity syndrome.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:3

    Topics: Anticonvulsants; Child, Preschool; Diazepam; Drug Hypersensitivity; Female; Hospitals, Pediatric; Ho

1993
Human herpesvirus 6 infection associated with anticonvulsant hypersensitivity syndrome and reactive haemophagocytic syndrome.
    The British journal of dermatology, 1997, Volume: 137, Issue:4

    Topics: Adult; Anticonvulsants; Drug Hypersensitivity; Female; Herpesviridae Infections; Herpesvirus 6, Huma

1997
["Primary" orthostatic tremor. 10 clinical electrophysiologic observations].
    Revue neurologique, 1998, Volume: 154, Issue:4

    Topics: Adult; Aged; Anti-Anxiety Agents; Arm; Clonazepam; Diazepam; Electromyography; Female; Humans; Leg;

1998
Changes of the EEG paroxysmal pattern during felbamate therapy in Lennox-Gastaut syndrome: a case report.
    The International journal of neuroscience, 1998, Volume: 95, Issue:3-4

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Drug Therapy,

1998
[A case of fetal valproate syndrome with intractable wheezing due to submucosal tumor below the vocal cord].
    No to hattatsu = Brain and development, 1999, Volume: 31, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Fatal Outcome; Female; Humans; Infant; Infant,

1999
Antiepileptic hypersensitivity syndrome in children.
    The Annals of pharmacotherapy, 2001, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Anticonvulsants; Child; Diethylcarbamazi

2001
[The drug hypersensitivity syndrome or DRESS syndrome to phenobarbital].
    Allergie et immunologie, 2001, Volume: 33, Issue:4

    Topics: Aged; Anticonvulsants; Cholestasis, Intrahepatic; Drug Eruptions; Edema; Eosinophilia; Epilepsy; Fem

2001
Glucose transporter type 1 deficiency syndrome (Glut1DS): methylxanthines potentiate GLUT1 haploinsufficiency in vitro.
    Pediatric research, 2001, Volume: 50, Issue:2

    Topics: 3-O-Methylglucose; Adolescent; Caffeine; Case-Control Studies; Child; Erythrocytes; Female; Humans;

2001
The fetal trimethadione syndrome.
    The Journal of pediatrics, 1975, Volume: 87, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anthropometry; Child, Preschool; Developmental

1975
The fetal hydantoin syndrome.
    The Journal of pediatrics, 1975, Volume: 87, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Child, Preschool; Developmental Di

1975
[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome].
    Arquivos de neuro-psiquiatria, 1977, Volume: 35, Issue:3

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Clonazepam; Dia

1977
The Zellweger syndrome: subcellular pathology, neuropathology, and the demonstration of pneumocystis carinii pneumonitis in two siblings.
    European journal of pediatrics, 1978, Apr-20, Volume: 127, Issue:4

    Topics: Abnormalities, Multiple; Autopsy; Brain; Endoplasmic Reticulum; Female; Humans; Infant; Infant, Newb

1978
[Romano-Ward syndrome and left stellectomy. General review apropos of a recent case].
    Archives des maladies du coeur et des vaisseaux, 1977, Volume: 70, Issue:6

    Topics: Adult; Arrhythmias, Cardiac; Deafness; Diagnosis, Differential; Drug Therapy, Combination; Electroca

1977
Mental dullness associated with left frontal continuous focal discharge.
    Folia psychiatrica et neurologica japonica, 1977, Volume: 31, Issue:3

    Topics: Adult; Carbamazepine; Cognition Disorders; Electroencephalography; Epilepsy, Post-Traumatic; Frontal

1977
Relapsing neuropathy, cerebral atrophy and folate deficiency. A close association.
    Applied neurophysiology, 1979, Volume: 42, Issue:3

    Topics: Atrophy; Brain Diseases; Edema; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intesti

1979
[Lesions of the nervous system in premature children with "conjugated" jaundices].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:10

    Topics: Apnea; Eye Manifestations; Face; Humans; Infant, Newborn; Infant, Premature, Diseases; Jaundice, Neo

1979
Changes in heart rate associated with high-pressure convulsions in rodents.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1979, Volume: 47, Issue:4

    Topics: Age Factors; Animals; Atmospheric Pressure; Atropine; Bradycardia; Female; Heart Rate; Mice; Phenoba

1979
Enzyme induction in man: a study of the inducible systems of drug elimination.
    Acta medica Academiae Scientiarum Hungaricae, 1979, Volume: 36, Issue:1

    Topics: Adult; Anovulation; Biotransformation; Contraceptives, Oral; Enzyme Induction; Female; Glucuronates;

1979
Paroxysmal diaphragmatic flutter in a young infant.
    The Journal of the Indiana State Medical Association, 1976, Volume: 69, Issue:3

    Topics: Diaphragm; Humans; Infant; Phenobarbital; Syndrome

1976
[Prevention of the major hyperthermia syndrome in the infant].
    Archives francaises de pediatrie, 1976, Volume: 33, Issue:2

    Topics: Aspirin; Baths; Body Temperature Regulation; Child, Preschool; Clothing; Fever; Humans; Infant; Phen

1976
Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics.
    Journal of neurology, neurosurgery, and psychiatry, 1976, Volume: 39, Issue:12

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebellar Diseases; Chorea; Dyskinesia, Dr

1976
Comparison of treatments for congenital nonobstructive nonhaemolytic hyperbilirubinaemia.
    Archives of disease in childhood, 1975, Volume: 50, Issue:3

    Topics: Agar; Aspartic Acid; Bilirubin; Brain Damage, Chronic; Child, Preschool; Cholestyramine Resin; Dieta

1975
Chronic hyperbilirubinemia associated with hepatic uptake and storage impairment. A new syndrome resembling that of the mutant Southdown sheep.
    Gastroenterology, 1975, Volume: 69, Issue:4

    Topics: Adult; Animals; Bilirubin; Female; Humans; Hyperbilirubinemia; Liver; Mutation; Phenobarbital; Sheep

1975
Temporal-lobe seizures with additional foci treated by resection.
    Journal of neurosurgery, 1975, Volume: 43, Issue:5

    Topics: Adolescent; Adult; Brain Neoplasms; Child; Electrodes, Implanted; Electroencephalography; Epilepsy,

1975
Psychosocial management of patients with complex partial seizures.
    Advances in neurology, 1975, Volume: 11

    Topics: Adult; Alcoholism; Carbamazepine; Delivery of Health Care; Drug Administration Schedule; Epilepsy; E

1975
Phenobarbital-responsive episodic dyscontrol (rage) in dogs.
    Journal of the American Veterinary Medical Association, 1992, Nov-15, Volume: 201, Issue:10

    Topics: Aggression; Animals; Behavior, Animal; Dog Diseases; Dogs; Electroencephalography; Epilepsy, Tempora

1992
Low cerebrospinal fluid concentration of free gamma-aminobutyric acid in startle disease.
    Lancet (London, England), 1992, Jul-11, Volume: 340, Issue:8811

    Topics: Clonazepam; Electroencephalography; Female; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Phenob

1992
Antiepileptics and the development of congenital anomalies.
    Neurology, 1992, Volume: 42, Issue:4 Suppl 5

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Apgar Score; Birth Weight; Carbamazepine; Epilepsy; Fe

1992
Generalized pustulation as a manifestation of the anticonvulsant hypersensitivity syndrome.
    Archives of dermatology, 1991, Volume: 127, Issue:9

    Topics: Adult; Carbamazepine; Cross Reactions; Drug Eruptions; Facial Dermatoses; Humans; Male; Middle Aged;

1991
Benign nocturnal childhood occipital epilepsy: a new syndrome with nocturnal seizures, tonic deviation of the eyes, and vomiting.
    Journal of child neurology, 1989, Volume: 4, Issue:1

    Topics: Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Male; Nystagmus

1989
Crigler-Najjar syndrome types I and II. Clinical experience--King's College Hospital 1972-1978. Phenobarbitone, phototherapy and liver transplantation.
    Molecular aspects of medicine, 1987, Volume: 9, Issue:5

    Topics: Child; Child, Preschool; Crigler-Najjar Syndrome; Female; Humans; Hyperbilirubinemia, Hereditary; In

1987
Epilepsy.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effec

1974
Sedative-hypnotic dependence.
    American family physician, 1974, Volume: 10, Issue:3

    Topics: Attitude of Health Personnel; Attitude to Health; Diazepam; Dose-Response Relationship, Drug; Drug P

1974
Assessment of aminopyrine metabolism in man by breath analysis after oral administration of 14C-aminopyrine. Effects of phenobarbital, disulfiram and portal cirrhosis.
    The New England journal of medicine, 1974, Dec-26, Volume: 291, Issue:26

    Topics: Administration, Oral; Adult; Aged; Alcoholism; Aminopyrine; Breath Tests; Carbon Dioxide; Carbon Rad

1974
[Effect of ethanol and phenobarbital on liver UDPG-transferase and on serum bilirubin in patients with Gilbert's syndrome].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1972, Volume: 8, Issue:1

    Topics: Adult; Bilirubin; Enzyme Induction; Ethanol; Female; Hexosyltransferases; Humans; Hyperbilirubinemia

1972
Crigler-Najjar syndrome: an unusual course with development of neurologic damage at age eighteen.
    Pediatric research, 1974, Volume: 8, Issue:5

    Topics: Adolescent; Alkaline Phosphatase; Bilirubin; Brain Damage, Chronic; Brain Diseases; Carbon Monoxide;

1974