phenobarbital has been researched along with Soft Tissue Neoplasms in 2 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ten patients (three males and seven females) were treated for sarcoma with high-dose ifosfamide (IFO) according to a 4 g/m2 1 h i." | 5.08 | Phenobarbital administration does not affect high-dose ifosfamide pharmacokinetics in humans. ( Lokiec, F; Santoni, J; Tubiana-Hulin, M; Weill, S, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fröscher, W | 1 |
| Hoffmann, F | 1 |
| Lokiec, F | 1 |
| Santoni, J | 1 |
| Weill, S | 1 |
| Tubiana-Hulin, M | 1 |
1 trial available for phenobarbital and Soft Tissue Neoplasms
| Article | Year |
|---|---|
Phenobarbital administration does not affect high-dose ifosfamide pharmacokinetics in humans.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Area Under Curve; Chromatography, High Pressur | 1996 |
1 other study available for phenobarbital and Soft Tissue Neoplasms
| Article | Year |
|---|---|
[Dupuytren's contracture and phenobarbital administration in epilepsy patients].
Topics: Adolescent; Adult; Bone Neoplasms; Dupuytren Contracture; Epilepsy; Female; Fibroma; Foot Diseases; | 1983 |