phenobarbital has been researched along with Sleep Initiation and Maintenance Disorders in 18 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Occasionally, insomnia-induced debilitations may be remedied by long-term use of sedative/hypnotic drugs; some examples are given." | 1.27 | Specific effects of sedative/hypnotic drugs in the treatment of incapacitating chronic insomnia. ( Regestein, QR, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (88.89) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HAGENBUCHER, JT | 1 |
| KLEH, J | 1 |
| HINTON, JM | 1 |
| VELGHE, R | 1 |
| JONES, DP | 1 |
| JONES, EA | 1 |
| CHARRIOT, G | 1 |
| LAMBERT, PA | 1 |
| Halperin, JM | 1 |
| Miller, D | 1 |
| Iorio, LC | 1 |
| Hendrix, SL | 1 |
| Chelimsky, G | 1 |
| Chelimsky, T | 1 |
| Deweer, E | 1 |
| Bussone, G | 1 |
| Boiardi, A | 1 |
| Lazzaroni, M | 1 |
| Regestein, QR | 1 |
| Haider, I | 1 |
| Oswald, I | 1 |
| Kaneko, J | 1 |
| Takaishi, N | 1 |
| Ida, H | 1 |
| Abe, H | 1 |
| Hosaka, M | 1 |
| Andersen, T | 2 |
| Lingjaerde, O | 2 |
| Madalena, JC | 1 |
| Safiulin, RM | 1 |
| Nosovitskaia, SA | 1 |
1 review available for phenobarbital and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Nonestrogen management of menopausal symptoms.
Topics: Belladonna Alkaloids; Drug Combinations; Ergotamines; Female; Humans; Menopause; Methysergide; Pheno | 1997 |
5 trials available for phenobarbital and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
[Can the severe and chronic insomniac escape from barbiturates? A double blind, long-term clinical study of a new hypnotic].
Topics: Anti-Anxiety Agents; Clinical Trials as Topic; Drug Evaluation; Flunitrazepam; Humans; Phenobarbital | 1975 |
A psychotropic agent in the climacteric.
Topics: Adult; Climacteric; Clinical Trials as Topic; Diethylstilbestrol; Female; Headache; Humans; Middle A | 1972 |
[Clinical effect of nitrazepam on psychoneurosis with insomnia].
Topics: Adolescent; Adult; Benzazepines; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Middle Ag | 1969 |
Nitrazepam (Mogadon) as a sleep-inducing agent. An analysis based on a double-blind comparison with phenobarbitone.
Topics: Adult; Benzazepines; Clinical Trials as Topic; Depression; Female; Humans; Hypnotics and Sedatives; | 1969 |
Comparisons of hypnotic drugs.
Topics: Clinical Trials as Topic; Humans; Phenobarbital; Placebos; Sleep Initiation and Maintenance Disorder | 1970 |
12 other studies available for phenobarbital and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Treatment of insomnia in geriatric patients: double-blind study with methyprylon and pentobarbital.
Topics: Double-Blind Method; Geriatrics; Humans; Hypnotics and Sedatives; Patients; Pentobarbital; Phenobarb | 1962 |
A comparison of the effects of six barbiturates and a placebo on insomnia and motility in psychiatric patients.
Topics: Barbiturates; Double-Blind Method; Female; Hexobarbital; Humans; Hypnotics and Sedatives; Male; Midd | 1963 |
[CONTROLLED CLINICAL TRIAL OF A SLEEP INDUCER].
Topics: Amobarbital; Barbiturates; Geriatrics; Humans; Hypnotics and Sedatives; Methaqualone; Phenobarbital; | 1963 |
DRUGS FOR INSOMNIA.
Topics: Amobarbital; Child; Chloral Hydrate; Diphenhydramine; Humans; Paraldehyde; Phenobarbital; Promethazi | 1963 |
[THERAPEUTIC EFFECTS OF A HYPNOTIC COMPOUND WITH TRANQUILIZING PROPERTIES].
Topics: Anxiety; Anxiety Disorders; Depression; Humans; Hypnotics and Sedatives; Meprobamate; Neurotic Disor | 1964 |
Sleep-inducing effects of three hypnotics in a new model of insomnia in rats.
Topics: Animals; Disease Models, Animal; Electroencephalography; Electromyography; Flurazepam; Humans; Hypno | 1981 |
Familial association of autonomic and gastrointestinal symptoms.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Autonomic Nervous System Diseases; Child; Fatigue; Fem | 2001 |
[Controlled clinical trial of a new benzodiazepine (Ro 5-6901) active on sleep disorders].
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Drug Evaluation; Female; Flurazepam; Humans; Middle Ag | 1975 |
Specific effects of sedative/hypnotic drugs in the treatment of incapacitating chronic insomnia.
Topics: Adult; Aged; Diazepam; Female; Humans; Hydromorphone; Hypnotics and Sedatives; Male; Methaqualone; P | 1987 |
Late brain recovery processes after drug overdose.
Topics: Adult; Benzazepines; Brain; Delirium; Drug Tolerance; Electroencephalography; Female; Humans; Hypnot | 1970 |
[The striking euhypnic action of Ro-4-5360 as compared with phenobarbital evaluated by the sequential analysis method].
Topics: Humans; Hypnotics and Sedatives; Phenobarbital; Sleep Initiation and Maintenance Disorders | 1965 |
[On the effects of delayed-action hypnotic drugs].
Topics: Delayed-Action Preparations; Humans; Hypnotics and Sedatives; Phenobarbital; Sleep Initiation and Ma | 1966 |