phenobarbital has been researched along with Skin Neoplasms in 17 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Skin Neoplasms: Tumors or cancer of the SKIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two-stage carcinogenesis of mouse skin papillomas induced by 7,12-dimethylbenz[alpha]anthracene and 12-O-tetradecanoylphorbol 13-acetate, and mouse hepatic tumors induced by N-nitrosodiethylamine and phenobarbital, were inhibited by lantadenes." | 3.69 | Anti-tumor promoting activities of lantadenes on mouse skin tumors and mouse hepatic tumors. ( Inada, A; Nakanishi, T; Nishino, H; Sharma, OP; Tokuda, H, 1997) |
| " The IP bioavailability of DEMIS (1." | 1.26 | Dose-dependence and related studies on the pharmacokinetics of misonidazole and desmethylmisonidazole in mice. ( Workman, P, 1980) |
| " Dose-response studies of the capacity of 7,8-BF to inhibit DMBA tumor initiation revealed that 7,8-BF was an effective inhibitor at 2." | 1.26 | The effects of benzoflavones on polycyclic hydrocarbon metabolism and skin tumor initiation. ( Berry, DL; Digiovanni, J; Juchau, MR; Slaga, TJ; Thompson, S; Viaje, A, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (76.47) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kharoshankaya, L | 1 |
| Murray, DM | 1 |
| Bogue, C | 1 |
| Ahearne, C | 1 |
| Murphy, BP | 1 |
| Boylan, GB | 1 |
| Kapadia, GJ | 1 |
| Azuine, MA | 1 |
| Sridhar, R | 1 |
| Okuda, Y | 1 |
| Tsuruta, A | 1 |
| Ichiishi, E | 2 |
| Mukainake, T | 1 |
| Takasaki, M | 2 |
| Konoshima, T | 2 |
| Nishino, H | 3 |
| Tokuda, H | 3 |
| Wheldrake, JF | 1 |
| Marshall, J | 1 |
| Ramli, J | 1 |
| Murray, AW | 1 |
| Levin, W | 1 |
| Buening, MK | 1 |
| Wood, AW | 1 |
| Chang, RL | 1 |
| Kedzierski, B | 1 |
| Thakker, DR | 1 |
| Boyd, DR | 1 |
| Gadaginamath, GS | 1 |
| Armstrong, RN | 1 |
| Yagi, H | 1 |
| Karle, JM | 1 |
| Slaga, TJ | 3 |
| Jerina, DM | 1 |
| Conney, AH | 1 |
| Workman, P | 1 |
| Inada, A | 1 |
| Nakanishi, T | 1 |
| Sharma, OP | 1 |
| Murakami, T | 1 |
| Duc, NM | 1 |
| Kasai, R | 1 |
| Yamasaki, K | 1 |
| Wislocki, PG | 1 |
| Miller, EC | 1 |
| Miller, JA | 1 |
| McCoy, EC | 1 |
| Rosenkranz, HS | 1 |
| Pitot, HC | 1 |
| Thompson, S | 1 |
| Berry, DL | 1 |
| Digiovanni, J | 1 |
| Juchau, MR | 1 |
| Viaje, A | 1 |
| Black, HS | 1 |
| Chan, JT | 1 |
| Brown, GE | 1 |
| Kirby, JD | 1 |
| Darley, CR | 1 |
| Grube, DD | 1 |
| Peraino, C | 1 |
| Fry, RJ | 1 |
| Naik, RP | 1 |
| Srinivas, CR | 1 |
| Das, PC | 1 |
| Ward, JM | 1 |
| Diwan, BA | 1 |
| Ohshima, M | 1 |
| Hu, H | 1 |
| Schuller, HM | 1 |
| Rice, JM | 1 |
| Bowden, GT | 1 |
| Shapas, BG | 1 |
| Boutwell, RK | 1 |
| Tripp, JH | 1 |
| Joseph, MC | 1 |
| Reay, HA | 1 |
17 other studies available for phenobarbital and Skin Neoplasms
| Article | Year |
|---|---|
Early EEG findings in tuberous sclerosis complex presenting with apneic seizures soon after birth.
Topics: Anticonvulsants; Apnea; Electroencephalography; Humans; Infant, Newborn; Magnetic Resonance Imaging; | 2016 |
Chemoprevention of DMBA-induced UV-B promoted, NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Beta vulgaris; Betacyanins; Body | 2003 |
Skin carcinogenesis and promoter binding characteristics in different mouse strains.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Croton Oil; Female; Methylcholanthrene; Mice | 1982 |
An enantiomeric interaction in the metabolism and tumorigenicity of (+)- and (-)-benzo[a]pyrene 7,8-oxide.
Topics: Animals; Benzopyrenes; Carcinogens; Cricetinae; Epoxide Hydrolases; Female; Humans; Kinetics; Male; | 1980 |
Dose-dependence and related studies on the pharmacokinetics of misonidazole and desmethylmisonidazole in mice.
Topics: Animals; Biological Availability; Body Temperature; Dose-Response Relationship, Drug; Female; Half-L | 1980 |
Anti-tumor promoting activities of lantadenes on mouse skin tumors and mouse hepatic tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Diethylnitrosamine; | 1997 |
Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis.
Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Diethylnitr | 1999 |
Carcinogenic and mutagenic activities of safrole, 1'-hydroxysafrole, and some known or possible metabolites.
Topics: Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellular; Dioxoles; Female; Liver; Liver Ne | 1977 |
The stability of events in the natural history of neoplasia.
Topics: Animals; Carcinoma, Hepatocellular; Humans; Liver; Liver Neoplasms; Mammary Neoplasms, Experimental; | 1977 |
The effects of benzoflavones on polycyclic hydrocarbon metabolism and skin tumor initiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzopyrene Hydroxylase; Carcinoma; D | 1977 |
Effects of dietary constituents on ultraviolet light-mediated carcinogenesis.
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Diet; Disulfiram; Female; Glutathione; Keratosis; M | 1978 |
Eruptive melanocytic naevi following severe bullous disease.
Topics: Child; Female; Humans; Male; Nevus, Pigmented; Phenobarbital; Phenytoin; Skin Neoplasms; Stevens-Joh | 1978 |
The effect ofdietary phenobarbital on the induction of skin tumors in hairless mice with 7, 12-dimethylbenz(a)anthracene.
Topics: Administration, Oral; Animal Feed; Animals; Benz(a)Anthracenes; Diet; Dose-Response Relationship, Dr | 1975 |
Generalized drug reaction sparing nevus depigmentosus.
Topics: Drug Eruptions; Humans; Male; Middle Aged; Nevus; Phenobarbital; Skin Neoplasms | 1986 |
Tumor-initiating and promoting activities of di(2-ethylhexyl) phthalate in vivo and in vitro.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; Diethylh | 1986 |
The role of aryl hydrocarbon hydroxylase in skin tumor initiation by 7,12-dimethylbenz(a)anthracene and 1,2,5,6-dibenzanthracene using DNA binding and thymidine-3H incorporation into DNA as criteria.
Topics: Administration, Topical; Animals; Benz(a)Anthracenes; Carcinogens; DNA; DNA, Neoplasm; Female; Flavo | 1974 |
A new neurocutaneous syndrome (skin, eye, brain and heart syndrome).
Topics: Aortic Coarctation; Child, Preschool; Electroencephalography; Eye Diseases; Female; Heart Diseases; | 1971 |