phenobarbital has been researched along with Seizures, Febrile in 126 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Seizures, Febrile: Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)
Excerpt | Relevance | Reference |
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" A 3-year-old boy developed alopecia areata (AA) universalis in the convalescent status of phenobarbital-induced AHS, compatible to the evidences of increased lymphocyte proliferation and increased dead cells percentages while his peripheral blood mononuclear cells were incubated with phenobarbital." | 7.75 | Alopecia areata universalis after phenobarbital-induced anti-convulsant hypersensitivity syndrome. ( Chen, ST; Hsiao, PF; Hsieh, MY; Huang, JL; Huang, YL; Kuo, HC; Lee, WI; Sheen, JM; Yang, KD; Yu, HR, 2009) |
"They conclude that epilepsy has a presentation rate of 9,6% in patients with previous febrile seizures, having the highest risk when they show previous familial seizures, neonatal pathology and altered EEG after the first febrile convulsion." | 5.26 | [Epilepsy after febrile seizures. Predisposing factors and role of phenobarbital in its prophylaxis (author's transl)]. ( Díez, JM; Palencia Luances, R; Sánchez-Villares, S; Tresierra, F, 1981) |
"Of 290 children with an initial febrile convulsion, 216 met Livingston's criteria for a "simple" febrile convulsion and 74 for "epilepsy triggered by fever." | 5.26 | Effectiveness of daily phenobarbital in the prevention of febrile seizure recurrences in "simple" febrile convulsions and "epilepsy triggered by fever". ( Wolf, SM, 1977) |
" Intermittent diazepam prophylaxis at times of fever may or may not reduce the recurrence rate significantly, but there is no data to suggest that it improves the long-term outcome, as compared with short-term seizure control, in terms of IQ, cognition, academic progress, motor control, and subsequent epilepsy." | 4.81 | [Febrile convulsions, Treatment and prognosis]. ( Knudsen, FU, 2001) |
" A 3-year-old boy developed alopecia areata (AA) universalis in the convalescent status of phenobarbital-induced AHS, compatible to the evidences of increased lymphocyte proliferation and increased dead cells percentages while his peripheral blood mononuclear cells were incubated with phenobarbital." | 3.75 | Alopecia areata universalis after phenobarbital-induced anti-convulsant hypersensitivity syndrome. ( Chen, ST; Hsiao, PF; Hsieh, MY; Huang, JL; Huang, YL; Kuo, HC; Lee, WI; Sheen, JM; Yang, KD; Yu, HR, 2009) |
" The administration of daily phenobarbital did not reduce the frequency of epilepsy, in spite of a significant reduction in the incidence of recurrent febrile seizures." | 3.67 | Epilepsy and mental retardation following febrile seizures in childhood. ( Forsythe, A; Wolf, SM, 1989) |
"Children with simple febrile convulsions were randomly allocated to receive either phenobarbitone or placebo." | 2.67 | Role of phenobarbitone in preventing recurrence of febrile convulsions. ( Ahamed, S; Banu, K; Kamala, KG; Krishnamurthy, PV; Thilothammal, N, 1993) |
"Phenytoin was an ineffective prophylactic agent." | 2.65 | Placebo-controlled study of phenobarbitone and phenytoin in the prophylaxis of febrile convulsions. ( Bacon, CJ; Hierons, AM; Mucklow, JC; Rawlins, MD; Webb, JK; Weightman, D, 1981) |
" They were subsequently followed up as outpatients, and Phenobarbital and sodium valproate levels were measured regularly to ascertain compliance with the treatment and to adjust the dosage accordingly." | 2.65 | Prevention of recurrent febrile convulsions--a randomized therapeutic assay: sodium valproate, phenobarbital and placebo. ( Gilly, R; Mamelle, JC; Mamelle, N; Plasse, JC; Revol, M, 1984) |
" Twelve hours later and then every 24 hours until the fever had subsided the dosage was 5 mg/kg orally or intramuscularly." | 2.65 | [Phenobarbital in febrile convulsions of children (author's transl)]. ( Lagenstein, I; Sternowsky, HJ, 1981) |
" The dosage was phenobarbitone 3-6 mg/kg per day; sodium valproate 30-60 mg/kg per day." | 2.65 | Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions. Comparison by a double-blind trial. ( Bower, B; Ngwane, E, 1980) |
"New convulsions were of similar duration and severity in both groups." | 2.64 | Prophylactic diazepam or phenobarbitone in febrile convulsions: a prospective, controlled study. ( Knudsen, FU; Vestermark, S, 1978) |
"13% had seizures which were either lateralized or longer than ten minutes." | 2.64 | The value of phenobarbital in the child who has had a single febrile seizure: a controlled prospective study. ( Carr, A; Dale, EP; Davidson, S; Davis, DC; Forsythe, A; Goldenberg, ED; Hanson, R; Lulejian, GA; Nelson, MA; Treitman, P; Weinstein, A; Wolf, SM, 1977) |
"Recurrences are common." | 2.42 | [Febrile seizures--an update]. ( Püst, B, 2004) |
"Febrile seizures are the most common seizure disorder in childhood, occurring in 2-5% of children." | 2.41 | Treatment of children with simple febrile seizures: the AAP practice parameter. American Academy of Pediatrics. ( Baumann, RJ; Duffner, PK, 2000) |
"The risk of recurrences was significantly lower in children receiving continuous phenobarbital therapy than placebo (odds ratio 0." | 2.40 | A meta-analytic review of the preventive treatment of recurrences of febrile seizures. ( Rantala, H; Tarkka, R; Uhari, M, 1997) |
"Febrile seizures are common in children." | 2.37 | The child with febrile seizures. ( Wright, SW, 1987) |
"Febrile seizures are a common occurrence in early childhood and most children who experience them do well." | 2.36 | The natural history of febrile seizures. ( Hirtz, DG; Nelson, KB, 1983) |
"The flupirtine-treated group showed less impairment in learning and memory and less obvious pathological changes in the brain following RFS compared with the phenobarbital-treated group." | 1.37 | Protective effect of the KCNQ activator flupirtine on a model of repetitive febrile seizures. ( He, X; Liu, W; Liu, Y; Peng, B; Wang, H; Wang, Y; Yin, J; Yu, F, 2011) |
"Five days later, febrile convulsions were induced by hyperthermal bath (45 Celcius degree)." | 1.36 | [Prophylactic efficacy of levetiracetam, valproate or phenobarbital on febrile convulsions in rats]. ( Cheng, M; Huang, Z; Li, SX, 2010) |
"Five patients had had several febrile seizures prior to the onset of prefebrile seizures." | 1.31 | [Apparently unprovoked seizures precipitated by prefebrile condition]. ( Hattori, H; Kato, T; Minamiura, Y; Murakami, M; Nakajima, T, 2000) |
"The families of 42 children with febrile seizures were recruited after pediatric or neuropediatric consultation." | 1.31 | Treatment of febrile seizures: the influence of treatment efficacy and side-effect profile on value to parents. ( Camfield, CS; Camfield, PR; Dooley, JM; Gordon, KE; MacSween, J, 2001) |
"Simple febrile seizures that occur in children ages 6 months to 5 years are common events with few adverse outcomes." | 1.30 | Technical report: treatment of the child with simple febrile seizures. ( Baumann, RJ, 1999) |
"Complex febrile seizures, affecting an estimated 5000 children in Illinois, were treated with phenobarbital by 90% of respondents, and therapy was continued for an average of 2 years." | 1.28 | Management of febrile seizures: current concepts and recommendations for phenobarbital and the electroencephalogram. ( Millichap, JG, 1991) |
"Only when the epilepsy is uncontrolled despite high plasma concentrations which cannot be raised because of side effects, a second drug should be given." | 1.27 | [Pharmacotherapy of epilepsy--current problems and controversies]. ( Schmidt, D, 1983) |
"Diazepam was found to be as effective as oral phenobarbital in the prevention of new febrile seizures." | 1.27 | [Continuous oral phenobarbital or intermittent rectal diazepam for the prevention of febrile convulsions]. ( Campos-Castelló, J; Careaga Maldonado, J; Oliete García, F, 1984) |
"Percentage of recurrences in phenobarbital treated cases (4 +/- 0,6 mg/Kg/d) was 18,67%, versus 55,89% in untreated children (p less than 0." | 1.27 | [Efficacy and failure of phenobarbital in the prevention of febrile convulsions. Importance of familial antecedents]. ( Blanco, A; Cilleruelo, ML; Palencia, R; Tresierra, F, 1983) |
"In the analysis of 128 patients with febrile convulsions, we identified hazards not encountered in the western world, which could alter the ultimate management of the child." | 1.27 | Management of febrile seizures in a developing country. ( Canagarayar, UT; Soysa, P, 1987) |
"When phenobarbital was withdrawn, the treated twin's behavior showed immediate improvement." | 1.27 | Effects of phenobarbital on early intellectual and behavioral development: a concordant twin case study. ( Byrne, JM; Camfield, PR; Clark-Touesnard, M; Hondas, BJ, 1987) |
" The plasma level/dosage ratio has been found to have a highly significant correlation with the age of the patient both for dosage in mg/kg and in mg/m2." | 1.26 | Correlation between age and plasma level/dosage ratio for phenobarbital in infants and children. ( Nino, LM; Principi, N; Rossi, LN, 1979) |
"The risk of another febrile convulsion is approximately 30%." | 1.26 | Continuous phenobarbital treatment after a 'simple febril convulsion'. ( Pollack, MA, 1978) |
"in 33 patients." | 1.26 | Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions. ( Minagawa, K; Miura, H, 1981) |
"Of 290 children with an initial febrile convulsion, 216 met Livingston's criteria for a "simple" febrile convulsion and 74 for "epilepsy triggered by fever." | 1.26 | Effectiveness of daily phenobarbital in the prevention of febrile seizure recurrences in "simple" febrile convulsions and "epilepsy triggered by fever". ( Wolf, SM, 1977) |
"Phenobarbital has been shown to offer effective prophylaxis against childhood febrile convulsions." | 1.26 | Sodium valproate versus phenobarbital in the prophylactic treatment of febrile convulsions in childhood. ( Lee, K; Melchior, JC, 1981) |
" Thus in adequate dosage both phenobarbitone and valproic acid were significantly better than no treatment in preventing febrile convulsions (p less than 0." | 1.26 | Successful prophylaxis against febrile convulsions with valproic acid or phenobarbitone. ( Smith, JA; Wallace, SJ, 1980) |
"They conclude that epilepsy has a presentation rate of 9,6% in patients with previous febrile seizures, having the highest risk when they show previous familial seizures, neonatal pathology and altered EEG after the first febrile convulsion." | 1.26 | [Epilepsy after febrile seizures. Predisposing factors and role of phenobarbital in its prophylaxis (author's transl)]. ( Díez, JM; Palencia Luances, R; Sánchez-Villares, S; Tresierra, F, 1981) |
" Saliva samples were easily obtained and the measured concentrations were a valuable guide to drug dosage during the treatment period." | 1.26 | Monitoring of phenobarbitone and phenytoin therapy in small children by salivary samples. ( Bacon, CJ; Hierons, AM; Mucklow, JC; Rawlins, MD; Webb, JK, 1981) |
"A Consensus Development Conference on Febrile Seizures was held at the National Institutes of Health in USA in May 1980." | 1.26 | ["Fever convulsions" in children. Current viewpoints on diagnosis, therapy and prognosis]. ( Helwig, H; Staudt, F, 1982) |
"Febrile convulsions occur in 3." | 1.26 | Febrile convulsions. ( Curry, HB, 1980) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 98 (77.78) | 18.7374 |
1990's | 15 (11.90) | 18.2507 |
2000's | 8 (6.35) | 29.6817 |
2010's | 3 (2.38) | 24.3611 |
2020's | 2 (1.59) | 2.80 |
Authors | Studies |
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Polavarapu, A | 1 |
Moshé, SL | 1 |
Renda, R | 1 |
Yüksel, D | 1 |
Gürer, YKY | 1 |
Wolski, TP | 1 |
Blasick, S | 1 |
Blackford, MG | 1 |
Huang, YL | 1 |
Hsieh, MY | 1 |
Hsiao, PF | 1 |
Sheen, JM | 1 |
Yu, HR | 1 |
Kuo, HC | 1 |
Chen, ST | 1 |
Huang, JL | 1 |
Yang, KD | 1 |
Lee, WI | 1 |
Cheng, M | 1 |
Huang, Z | 1 |
Li, SX | 1 |
Yu, F | 1 |
Liu, Y | 1 |
Wang, Y | 1 |
Yin, J | 1 |
Wang, H | 1 |
Liu, W | 1 |
Peng, B | 1 |
He, X | 1 |
MILLICHAP, JG | 2 |
ALEDORT, LM | 1 |
MADSEN, JA | 1 |
Masuko, AH | 1 |
Castro, AA | 1 |
Santos, GR | 1 |
Atallah, AN | 1 |
do Prado, LB | 1 |
de Carvalho, LB | 1 |
do Prado, GF | 1 |
Püst, B | 1 |
Bacon, CJ | 3 |
Hierons, AM | 3 |
Mucklow, JC | 2 |
Webb, JK | 3 |
Rawlins, MD | 3 |
Weightman, D | 1 |
Stephenson, JB | 1 |
Hirtz, DG | 3 |
Nelson, KB | 2 |
Antony, JH | 1 |
Hawke, SH | 1 |
Johnson, DD | 1 |
Crawford, KD | 1 |
Crawford, RD | 1 |
Escorihuela, R | 1 |
Sandiumenge, J | 1 |
Schmidt, D | 1 |
Herranz, JL | 1 |
Armijo, JA | 1 |
Arteaga, R | 1 |
Olson, JE | 1 |
Scher, MS | 1 |
Holtzman, D | 1 |
Mamelle, N | 2 |
Mamelle, JC | 2 |
Plasse, JC | 2 |
Revol, M | 2 |
Gilly, R | 2 |
Gram, L | 1 |
Bentsen, KD | 1 |
Zanini, R | 1 |
Caminiti, A | 1 |
Bollati, A | 1 |
Focarile, F | 1 |
Rondanini, GF | 1 |
Grasso, E | 1 |
Oliete García, F | 1 |
Campos-Castelló, J | 1 |
Careaga Maldonado, J | 1 |
Palencia, R | 1 |
Cilleruelo, ML | 1 |
Tresierra, F | 2 |
Blanco, A | 1 |
Wallace, SJ | 3 |
Haddock, ST | 1 |
Smith, JA | 2 |
Ngwane, E | 1 |
Bower, B | 1 |
Cowen, J | 1 |
Harris, F | 1 |
Masala, A | 1 |
Meloni, T | 1 |
Alagna, S | 1 |
Rovasio, PP | 1 |
Mele, G | 1 |
Franca, V | 1 |
Pearce, JL | 2 |
Giles, HM | 1 |
Addy, DP | 2 |
Lee, K | 1 |
Melchior, JC | 1 |
Minagawa, K | 1 |
Miura, H | 1 |
Staudt, F | 1 |
Helwig, H | 1 |
Nurchi, AM | 1 |
Cappai, A | 1 |
Repetto, C | 1 |
Byrge, H | 1 |
Kragstrup, J | 1 |
Lund, HT | 1 |
Camfield, PR | 5 |
Camfield, CS | 4 |
Tibbles, JA | 1 |
Pilgaard, S | 1 |
Hansen, FJ | 1 |
Paerregaard, P | 1 |
Nakamura, M | 1 |
Kajitani, T | 1 |
Cranage, JD | 1 |
Wolf, SM | 7 |
Forsythe, A | 4 |
Stunden, AA | 1 |
Friedman, R | 1 |
Diamond, H | 1 |
Palencia Luances, R | 1 |
Díez, JM | 1 |
Sánchez-Villares, S | 1 |
Curry, HB | 1 |
Shapiro, SH | 2 |
Cummings, C | 2 |
Valman, HB | 1 |
Schain, RJ | 1 |
Sternowsky, HJ | 1 |
Lagenstein, I | 2 |
Coker, SB | 1 |
Domizio, S | 1 |
Verrotti, A | 1 |
Ramenghi, LA | 1 |
Sabatino, G | 1 |
Morgese, G | 1 |
Thilothammal, N | 1 |
Krishnamurthy, PV | 1 |
Kamala, KG | 1 |
Ahamed, S | 1 |
Banu, K | 1 |
Rantala, H | 1 |
Tarkka, R | 1 |
Uhari, M | 1 |
Cavazzuti, GB | 1 |
Baumann, RJ | 2 |
Sulzbacher, S | 1 |
Farwell, JR | 2 |
Temkin, N | 1 |
Lu, AS | 1 |
Minamiura, Y | 1 |
Hattori, H | 1 |
Nakajima, T | 1 |
Murakami, M | 1 |
Kato, T | 1 |
Duffner, PK | 1 |
Knudsen, FU | 4 |
Gordon, KE | 1 |
Dooley, JM | 1 |
MacSween, J | 1 |
Autret-Leca, E | 1 |
Ployet, JL | 1 |
Jonville-Bera, AP | 1 |
Sharman, JR | 1 |
Forster, RM | 1 |
Trubuhovich, RV | 1 |
Julien, RM | 2 |
Fowler, GW | 2 |
Vestermark, S | 2 |
Fishman, MA | 2 |
Livingston, S | 2 |
Pauli, LL | 2 |
Pruce, I | 2 |
Kramer, II | 2 |
Chaplin, S | 1 |
Doyle, AB | 1 |
Borgheresi, S | 1 |
Luti, E | 1 |
Buti Cossi, D | 1 |
Mecherini, L | 1 |
Bardini, MR | 1 |
Burgio, E | 1 |
Ciampi, C | 1 |
Benocci, M | 1 |
Massai, S | 1 |
Lini, M | 1 |
Grifi, G | 1 |
Valenza, T | 1 |
Swanson, PD | 1 |
Benítez, J | 1 |
Dalhqvist, R | 1 |
Rossi, LN | 1 |
Nino, LM | 1 |
Principi, N | 1 |
MacDonald, JT | 1 |
Pollack, MA | 1 |
Ellsworth, A | 1 |
Thompson, FL | 1 |
Freeman, JM | 2 |
Pascoe, JM | 1 |
Schnitzker, WF | 1 |
Ounsted, C | 1 |
Gorman, RJ | 1 |
Snead, OC | 1 |
Carr, A | 1 |
Davis, DC | 1 |
Davidson, S | 1 |
Dale, EP | 1 |
Goldenberg, ED | 1 |
Hanson, R | 1 |
Lulejian, GA | 1 |
Nelson, MA | 1 |
Treitman, P | 1 |
Weinstein, A | 1 |
Jalling, B | 1 |
Baldellou Vázquez, A | 1 |
Gomá Brufau, A | 1 |
Vargas Torcal, F | 1 |
Pastor Mourón, I | 1 |
Ros Mar, L | 1 |
Ferrández Longás, A | 1 |
Tomasi, LG | 1 |
Wässer, S | 2 |
Wässer, R | 2 |
Vajnorský, J | 1 |
Gutová, M | 1 |
Ulrychová, Z | 1 |
Vigevano, F | 1 |
Di Capua, M | 1 |
Fusco, L | 1 |
Ricci, S | 1 |
Sebastianelli, R | 1 |
Lucchini, P | 1 |
Placencia, M | 1 |
Suarez, J | 1 |
Crespo, F | 1 |
Sander, JW | 1 |
Shorvon, SD | 1 |
Ellison, RH | 1 |
Cascante, SM | 1 |
Ehrhardt, P | 1 |
Miceli Sopo, S | 1 |
Pesaresi, MA | 1 |
Celestini, E | 1 |
Stabile, A | 1 |
Lee, YJ | 1 |
Sulzbacher, SI | 1 |
Ellenberg, JH | 1 |
McKinlay, I | 1 |
Newton, R | 1 |
Saw, AH | 1 |
Ho, L | 1 |
Lim, KW | 1 |
Cheng, HK | 1 |
Rosman, NP | 1 |
Newton, RW | 1 |
Rohmann, E | 1 |
Sengbusch, S | 1 |
Hobusch, D | 1 |
Popp, K | 1 |
Schwebke, D | 1 |
Wright, SW | 1 |
Huang, SW | 1 |
Somasundram, P | 1 |
Tan, CL | 1 |
Byrne, JM | 1 |
Clark-Touesnard, M | 1 |
Hondas, BJ | 1 |
Canagarayar, UT | 1 |
Soysa, P | 1 |
Vining, EP | 1 |
Giroud, M | 1 |
Dumas, R | 1 |
Rothe, B | 1 |
Herranz Fernández, JL | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
An MRI Ancillary Study of a Malaria Fever Randomized Controlled Trial (RCT)[NCT05746819] | 256 participants (Anticipated) | Observational | 2021-01-02 | Enrolling by invitation | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
14 reviews available for phenobarbital and Seizures, Febrile
Article | Year |
---|---|
Intermittent diazepam and continuous phenobarbital to treat recurrence of febrile seizures: a systematic review with meta-analysis.
Topics: Anticonvulsants; Diazepam; Follow-Up Studies; Humans; Odds Ratio; Phenobarbital; Placebos; Randomize | 2003 |
[Febrile seizures--an update].
Topics: Administration, Oral; Administration, Rectal; Age Factors; Analgesics, Non-Narcotic; Anticonvulsants | 2004 |
The natural history of febrile seizures.
Topics: Animals; Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Infant | 1983 |
[Use of phenobarbital in febrile convulsive crisis].
Topics: Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Nervous System Diseases; Phenobarbital; Recurr | 1983 |
A meta-analytic review of the preventive treatment of recurrences of febrile seizures.
Topics: Anticonvulsants; Chi-Square Distribution; Child; Diazepam; Drug Administration Schedule; Fever; Huma | 1997 |
Treatment of children with simple febrile seizures: the AAP practice parameter. American Academy of Pediatrics.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combin | 2000 |
[Febrile convulsions, Treatment and prognosis].
Topics: Analgesics, Non-Narcotic; Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phe | 2001 |
Febrile seizures: the treatment controversy.
Topics: Child; Epilepsy; Humans; Nervous System Diseases; Phenobarbital; Phenytoin; Recurrence; Seizures; Se | 1979 |
Febrile convulsions: diagnosis, treatment, and prognosis.
Topics: Child; Epilepsy; Humans; Infant; Intellectual Disability; Intelligence; Meningitis; Phenobarbital; P | 1979 |
[Prevention of recurrences and of epilepsy in febrile convulsions. Protocol of the Pediatric Clinic of the Florence and preliminary results].
Topics: Age Factors; Child; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phenobarbital; Recurrence; | 1979 |
Phenobarbitone and febrile convulsions.
Topics: Humans; Infant; Intelligence; Phenobarbital; Seizures, Febrile; Time Factors; Valproic Acid | 1990 |
Febrile seizures.
Topics: Child; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencephalography; Epilepsy; Female | 1987 |
The child with febrile seizures.
Topics: Child, Preschool; Diagnosis, Differential; Diazepam; Fever; Humans; Infant; Phenobarbital; Prognosis | 1987 |
Seizures which are not epilepsy.
Topics: Child, Preschool; Epilepsies, Partial; Fever; Humans; Hypocalcemia; Hypoglycemia; Infant; Infant, Ne | 1985 |
23 trials available for phenobarbital and Seizures, Febrile
Article | Year |
---|---|
Placebo-controlled study of phenobarbitone and phenytoin in the prophylaxis of febrile convulsions.
Topics: Age Factors; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbi | 1981 |
Phenobarbital compared with carbamazepine in prevention of recurrent febrile convulsions. A double-blind study.
Topics: Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Inf | 1983 |
Prevention of recurrent febrile convulsions--a randomized therapeutic assay: sodium valproate, phenobarbital and placebo.
Topics: Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Electroencephalography | 1984 |
Controlled and comparative trials of valproate performed in Europe and Asia.
Topics: Adolescent; Adult; Asia; Carbamazepine; Child; Clinical Trials as Topic; Epilepsy; Europe; Humans; P | 1984 |
Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions. Comparison by a double-blind trial.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Random A | 1980 |
[Efficacy of sodium dipropylacetate compared with phenobarbital and placebo in the prevention of recurrence of febrile convulsions].
Topics: Child, Preschool; Clinical Trials as Topic; Female; Humans; Infant; Male; Phenobarbital; Placebos; R | 1982 |
Behavioural effects of phenobarbitone and phenytoin in small children.
Topics: Child Behavior Disorders; Female; Hospitalization; Humans; Infant; Male; Phenobarbital; Phenytoin; S | 1981 |
Long-term effect of phenobarbital on cognitive function in children with febrile convulsions.
Topics: Child; Child, Preschool; Cognition; Female; Humans; Male; Patient Compliance; Phenobarbital; Psychol | 1981 |
The first febrile seizure--antipyretic instruction plus either phenobarbital or placebo to prevent recurrence.
Topics: Child, Preschool; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Placebos; Seizur | 1980 |
[Phenobarbital in febrile convulsions of children (author's transl)].
Topics: Administration, Oral; Child, Preschool; Humans; Infant; Injections, Intramuscular; Phenobarbital; Se | 1981 |
Role of phenobarbitone in preventing recurrence of febrile convulsions.
Topics: Child; Child, Preschool; Double-Blind Method; Drug Tolerance; Epilepsies, Partial; Epilepsy, Tonic-C | 1993 |
Prevention of febrile convulsions with dipropylacetate (Depakine).
Topics: Anticonvulsants; Child, Preschool; Humans; Phenobarbital; Primidone; Seizures, Febrile; Valproic Aci | 1975 |
Late cognitive effects of early treatment with phenobarbital.
Topics: Child; Humans; Intelligence; Intelligence Tests; Male; Neurobehavioral Manifestations; Phenobarbital | 1999 |
[Prevention of febrile convulsions with diazepam or phenemal. A prospective controlled study].
Topics: Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Humans; Infant; Phenobarbital; Prospect | 1978 |
Prophylactic diazepam or phenobarbitone in febrile convulsions: a prospective, controlled study.
Topics: Child, Preschool; Clinical Trials as Topic; Diazepam; Female; Humans; Infant; Male; Phenobarbital; P | 1978 |
Side effects of phenobarbital in toddlers; behavioral and cognitive aspects.
Topics: Child Behavior Disorders; Child, Preschool; Clinical Trials as Topic; Cognition Disorders; Dose-Resp | 1979 |
The value of phenobarbital in the child who has had a single febrile seizure: a controlled prospective study.
Topics: Child, Preschool; Female; Humans; Infant; Male; Patient Compliance; Phenobarbital; Prospective Studi | 1977 |
Plasma-diazepam in infants after rectal administration in solution and by suppository.
Topics: Child, Preschool; Diazepam; Humans; Infant; Phenobarbital; Rectum; Seizures, Febrile; Solutions; Sup | 1977 |
A large-scale study of epilepsy in Ecuador: methodological aspects.
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Cross-Sectional Studies; Developing Count | 1992 |
Short-term prophylaxis of febrile convulsions.
Topics: Child; Child, Preschool; Diazepam; Female; Humans; Infant; Male; Phenobarbital; Prospective Studies; | 1991 |
Phenobarbital for febrile seizures--effects on intelligence and on seizure recurrence.
Topics: Child, Preschool; Cognition; Female; Humans; Infant; Intelligence; Male; Phenobarbital; Randomized C | 1990 |
Intention to treat febrile convulsions with rectal diazepam, valproate or phenobarbitone.
Topics: Administration, Rectal; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Male; Phenobarbit | 1989 |
Randomised controlled trials of phenobarbitone and valproate in febrile convulsions.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Phenobarbital; Random Allocation; | 1988 |
89 other studies available for phenobarbital and Seizures, Febrile
Article | Year |
---|---|
50 Years Ago in TheJournalofPediatrics: Intermittent Phenobarbital Treatment to Prevent Recurrent Febrile Seizures.
Topics: Anticonvulsants; History, 20th Century; Humans; Pediatrics; Periodicals as Topic; Phenobarbital; Rec | 2021 |
Evaluation of Patients With Febrile Seizure: Risk Factors, Reccurence, Treatment and Prognosis.
Topics: Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Female; Fever; Humans; Infant; | 2020 |
The Case of the Previously Shaky, Unimmunized, Itchy Infant With Rash and Pancytopenia.
Topics: Anticonvulsants; Antipyretics; Drug Hypersensitivity Syndrome; Exanthema; Humans; Infant; Male; Panc | 2016 |
Alopecia areata universalis after phenobarbital-induced anti-convulsant hypersensitivity syndrome.
Topics: Alopecia Areata; Anticonvulsants; Child, Preschool; Drug Hypersensitivity; Humans; Male; Phenobarbit | 2009 |
[Prophylactic efficacy of levetiracetam, valproate or phenobarbital on febrile convulsions in rats].
Topics: Animals; Anticonvulsants; Levetiracetam; Male; Phenobarbital; Piracetam; Rats; Recurrence; Seizures, | 2010 |
Protective effect of the KCNQ activator flupirtine on a model of repetitive febrile seizures.
Topics: Aminopyridines; Analgesics; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography | 2011 |
A critical evaluation of therapy of febrile seizures.
Topics: Child; Fever; Humans; Hydantoins; Infant; Phenobarbital; Seizures; Seizures, Febrile | 1960 |
Prophylaxis of febrile convulsions.
Topics: Humans; Infant; Phenobarbital; Phenytoin; Random Allocation; Seizures, Febrile | 1981 |
Phenobarbitone in the prophylaxis of febrile convulsions.
Topics: Humans; Phenobarbital; Recurrence; Seizures, Febrile | 1981 |
Febrile seizures in epileptic chicks: the effects of phenobarbital, phenytoin and valproate.
Topics: Animals; Chickens; Disease Models, Animal; Phenobarbital; Phenytoin; Reaction Time; Seizures, Febril | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, | 1983 |
Effectiveness and toxicity of phenobarbital, primidone, and sodium valproate in the prevention of febrile convulsions, controlled by plasma levels.
Topics: Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Male; Phenobarbital; Prim | 1984 |
Effects of anticonvulsants on hyperthermia-induced seizures in the rat pup.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Temperature; Differential Threshold; Disease Model | 1984 |
[Effects of phenobarbital on thyroid function in childhood. Iatrogenic TBG deficiency].
Topics: Child; Child, Preschool; Female; Humans; Iatrogenic Disease; Infant; Male; Phenobarbital; Seizures, | 1984 |
[Continuous oral phenobarbital or intermittent rectal diazepam for the prevention of febrile convulsions].
Topics: Administration, Oral; Child, Preschool; Diazepam; Female; Humans; Infant; Longitudinal Studies; Male | 1984 |
[Efficacy and failure of phenobarbital in the prevention of febrile convulsions. Importance of familial antecedents].
Topics: Age Factors; Epilepsy; Female; Fetal Hypoxia; Humans; Male; Phenobarbital; Pregnancy; Recurrence; Se | 1983 |
Febrile convulsions: their significance for later intellectual development and behaviour.
Topics: Child; Child Behavior Disorders; Child Development; Child, Preschool; Female; Follow-Up Studies; Hum | 1984 |
Drug treatment of recurrent febrile seizures.
Topics: Antacids; Child; Humans; Phenobarbital; Recurrence; Seizures, Febrile | 1984 |
Successful prophylaxis against febrile convulsions with valproic acid or phenobarbitone.
Topics: Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Recurrence; Seizures; Seizures, Febri | 1980 |
Prophylaxis against febrile convulsions.
Topics: Child; Humans; Phenobarbital; Seizures; Seizures, Febrile; Valproic Acid | 1980 |
Prophylaxis against febrile convulsions.
Topics: Child, Preschool; Diagnosis, Differential; Epilepsy; Humans; Infant; Phenobarbital; Seizures; Seizur | 1980 |
Pituitary responsiveness to gonadotrophin-releasing and thyrotrophin-releasing hormones in children receiving phenobarbitone.
Topics: Child, Preschool; Follicle Stimulating Hormone; Humans; Infant; Long-Term Care; Luteinizing Hormone; | 1980 |
Prevention of simple febrile convulsions.
Topics: Child; Humans; Phenobarbital; Seizures; Seizures, Febrile; Valproic Acid | 1980 |
Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions.
Topics: Humans; Infant; Infant, Newborn; Phenobarbital; Recurrence; Seizures; Seizures, Febrile; Valproic Ac | 1980 |
Prophylaxis and febrile convulsions.
Topics: Child; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phenobarbital; Recurrence; Seizures; Se | 1981 |
Febrile convulsions: long-term treatment.
Topics: Anticonvulsants; Child; Child, Preschool; Humans; Infant; Phenobarbital; Prognosis; Recurrence; Seiz | 1981 |
Sodium valproate versus phenobarbital in the prophylactic treatment of febrile convulsions in childhood.
Topics: Child Behavior Disorders; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Seizures, F | 1981 |
Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions.
Topics: Child, Preschool; Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Primidone; Recurr | 1981 |
Febrile convulsions: intellectual progress in relation to anticonvulsant therapy and to recurrence of fits.
Topics: Child Development; Child, Preschool; Humans; Infant; Intelligence; Intelligence Tests; Phenobarbital | 1982 |
["Fever convulsions" in children. Current viewpoints on diagnosis, therapy and prognosis].
Topics: Child, Preschool; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Parents; Phenobarbita | 1982 |
[Simple or benign febrile convulsions. Clinical and statistical evaluation].
Topics: Age Factors; Child; Humans; Phenobarbital; Seizures, Febrile; Sex Factors | 1982 |
[Continuing treatment with phenemal in prevention of febrile convulsions. A report of children with the first febrile convulsions treated during 2 years].
Topics: Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Seizures, Febrile | 1982 |
Carbamazepine does not prevent febrile seizures in phenobarbital failures.
Topics: Carbamazepine; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Recurrence; Seizures, | 1982 |
Prophylaxis against febrile convulsions with phenobarbital. A 3-year prospective investigation.
Topics: Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Male; Phenobarbital; Prospective | 1981 |
A study on serum concentration of phenobarbital in epileptic children and children with febrile convulsions.
Topics: Child; Epilepsy; Humans; Phenobarbital; Seizures; Seizures, Febrile | 1980 |
Monitoring of phenobarbitone and phenytoin therapy in small children by salivary samples.
Topics: Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Phenytoin; Saliva; Seizures, Febril | 1981 |
[Epilepsy after febrile seizures. Predisposing factors and role of phenobarbital in its prophylaxis (author's transl)].
Topics: Age Factors; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Infant; Infant, New | 1981 |
Febrile convulsions.
Topics: Child, Preschool; Epilepsy; Humans; Infant; Male; Phenobarbital; Prognosis; Seizures; Seizures, Febr | 1980 |
The first year of life. Convulsions in the older infant.
Topics: Diazepam; First Aid; Humans; Hyaluronoglucosaminidase; Infant; Paraldehyde; Phenobarbital; Seizures; | 1980 |
Febrile seizures: long-term management of children with fever-associated seizures. Summary of an NIH consensus statement.
Topics: Child, Preschool; Diazepam; Epilepsy; Fever; Humans; Infant; Phenobarbital; Risk; Seizures; Seizures | 1980 |
Phenobarbital in neurologically handicapped children.
Topics: Brain Damage, Chronic; Child; Humans; Intellectual Disability; Nervous System Diseases; Phenobarbita | 1981 |
Childhood febrile convulsions.
Topics: Child; Epilepsy; Hippocampus; Humans; Phenobarbital; Sclerosis; Seizures, Febrile | 1994 |
Anti-epileptic therapy and behaviour disturbances in children.
Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Chi | 1993 |
Jury finds pharmacy's misfilling of prescription caused child's brain damage.
Topics: Brain Damage, Chronic; California; Child; Female; Humans; Liability, Legal; Medication Errors; Pharm | 1999 |
Technical report: treatment of the child with simple febrile seizures.
Topics: Analgesics, Non-Narcotic; Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phe | 1999 |
[Apparently unprovoked seizures precipitated by prefebrile condition].
Topics: Anticonvulsants; Body Temperature; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Humans; In | 2000 |
Treatment of febrile seizures: the influence of treatment efficacy and side-effect profile on value to parents.
Topics: Adult; Anticonvulsants; Anxiety; Attitude; Child, Preschool; Diazepam; Educational Status; Female; H | 2001 |
[Treatment of febrile convulsions].
Topics: Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child, Preschool; Diazepam; D | 2002 |
Phenobarbital in the acute management of febrile convulsions.
Topics: Child, Preschool; Humans; Infant; Injections, Intramuscular; Phenobarbital; Seizures, Febrile | 1977 |
The initial management of simple febrile seizures.
Topics: Child; Humans; Phenobarbital; Seizures; Seizures, Febrile | 1978 |
A comparative study of the efficacy of newer antiepiletpic drugs on experimentally-induced febrile convulsions.
Topics: Animals; Anticonvulsants; Body Temperature; Carbamazepine; Clonazepam; Male; Mice; Phenobarbital; Se | 1977 |
Anticonvulsant therapy. Approaches to some common clinical problems.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Eth | 1979 |
Continuous phenobarbital treatment after a 'simple febrile convulsion'.
Topics: Animals; Child; Epilepsy; Humans; Phenobarbital; Recurrence; Seizures; Seizures, Febrile | 1979 |
[Continuous administration of phenobarbital as prevention of febrile convulsions in children. Critical review].
Topics: Child, Preschool; Female; Humans; Infant; Male; Methods; Phenobarbital; Seizures; Seizures, Febrile | 1979 |
Correlation between age and plasma level/dosage ratio for phenobarbital in infants and children.
Topics: Age Factors; Body Weight; Child; Child, Preschool; Epilepsy; Humans; Infant; Phenobarbital; Seizures | 1979 |
Commentary: side effects of phenobarbital.
Topics: Child, Preschool; Cognition Disorders; Humans; Intelligence; Intelligence Tests; Phenobarbital; Seiz | 1979 |
Febrile convulsions--current controversies.
Topics: Child, Preschool; Humans; Infant; Infant, Newborn; Phenobarbital; Prognosis; Risk; Seizures; Seizure | 1979 |
Controversies in the treatment of febrile convulsions.
Topics: Child; Epilepsy; Humans; Intelligence; Phenobarbital; Phenytoin; Prognosis; Seizures; Seizures, Febr | 1979 |
Continuous phenobarbital treatment after a 'simple febril convulsion'.
Topics: Child; Epilepsy; Humans; Phenobarbital; Seizures; Seizures, Febrile; Time Factors | 1978 |
Phenobarbital for febrile convulsions.
Topics: Administration, Oral; Child; Humans; Phenobarbital; Seizures; Seizures, Febrile | 1978 |
Behavior disturbance, phenobarbital, and febrile seizures.
Topics: Barbiturates; Child Behavior Disorders; Humans; Hyperkinesis; Mephobarbital; Phenobarbital; Recurren | 1978 |
Febrile seizures: an end to confusion.
Topics: Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Hyperkinesis; Infant; Infant, | 1978 |
Simple febrile seizures.
Topics: Child; Community Participation; Decision Making; Humans; Parents; Phenobarbital; Recurrence; Seizure | 1978 |
'Simple febrile convulsion'.
Topics: Humans; Phenobarbital; Recurrence; Seizures; Seizures, Febrile | 1978 |
Phenobarbital and febrile seizures.
Topics: Drug Administration Schedule; Humans; Phenobarbital; Recurrence; Seizures; Seizures, Febrile | 1978 |
Preventing febrile convulsions.
Topics: Child, Preschool; Diazepam; Humans; Infant; Phenobarbital; Seizures; Seizures, Febrile | 1978 |
Febrile seizures.
Topics: Anticonvulsants; Child; Humans; Phenobarbital; Seizures; Seizures, Febrile | 1979 |
[Phenemal prophylaxis and prognosis].
Topics: Child; Child, Preschool; Epilepsy; Humans; Infant; Phenobarbital; Prognosis; Recurrence; Seizures; S | 1977 |
Effectiveness of daily phenobarbital in the prevention of febrile seizure recurrences in "simple" febrile convulsions and "epilepsy triggered by fever".
Topics: Child; Diagnosis, Differential; Epilepsy; Humans; Phenobarbital; Seizures; Seizures, Febrile | 1977 |
Effectiveness of N,N-dimethoxymethyl-phenobarbital (eterobarbital) on febrile seizures.
Topics: Administration, Oral; Animals; Injections, Intraperitoneal; Male; Mice; Phenobarbital; Seizures; Sei | 1977 |
The effectiveness of phenobarbital in the prevention of recurrent febrile convulsions in children with and without a history of pre-, peri- and postnatal abnormalities.
Topics: Child; Child, Preschool; Female; Follow-Up Studies; Humans; Obstetric Labor Complications; Phenobarb | 1977 |
[Height alterations and calcium metabolism after prolongated phenobarbital treatment (author's transl)].
Topics: Alkaline Phosphatase; Bone Development; Calcium; Growth; Growth Disorders; Humans; Infant; Phenobarb | 1977 |
Seizures in childhood encephalopathy or epilepsy?
Topics: Adolescent; Child; Epilepsy; Humans; Metabolic Diseases; Neurologic Examination; Phenobarbital; Prim | 1977 |
[Interval therapy of febrile convulsions for the management of their prognosis. I. Methods and therapeutic advice for interval therapy of febrile convulsions].
Topics: Child, Preschool; Epilepsy; Humans; Infant; Periodicity; Phenobarbital; Phenytoin; Recurrence; Seizu | 1976 |
[Interval therapy of febrile convulsions for management of the prognosis. II. Anticonvulsant longtime Fali-Lepsin therapy of complicated febrile convulsions].
Topics: Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Phenylpropanolamine; Progno | 1976 |
[Problems in the preventive treatment of repeated febrile convulsions].
Topics: Child; Child, Preschool; Chronic Disease; Female; Humans; Infant; Male; Phenobarbital; Prognosis; Re | 1976 |
Sixth-month benign familial convulsions.
Topics: Electroencephalography; Epilepsies, Partial; Female; Follow-Up Studies; Humans; Infant; Male; Phenob | 1992 |
Phenobarbitone and epilepsy.
Topics: Child; Humans; Phenobarbital; Seizures, Febrile | 1990 |
Management of febrile seizures: current concepts and recommendations for phenobarbital and the electroencephalogram.
Topics: Acute Disease; Child, Preschool; Drug Utilization; Electroencephalography; Family Practice; Humans; | 1991 |
Phenobarbital for febrile seizures.
Topics: Child; Humans; Intelligence; Phenobarbital; Seizures, Febrile | 1990 |
Febrile convulsion--a clinical survey and a review of its current concept of management.
Topics: Child; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Retrospective Studies; Seizure | 1989 |
Epilepsy and mental retardation following febrile seizures in childhood.
Topics: Child; Child, Preschool; Epilepsy; Humans; Infant; Intellectual Disability; Phenobarbital; Recurrenc | 1989 |
[Prognosis of complicated febrile convulsions in therapy with primidone, cathine-phenobarbital and calcium valproinate].
Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Male; Phenobarbital; Phe | 1988 |
The value of investigations, the significance of perinatal and family histories and the prevalence of side effects to phenobarbitone in children with recurrent seizures.
Topics: Child Behavior; Epilepsy; Female; Humans; Infant, Newborn; Male; Phenobarbital; Pregnancy; Recurrenc | 1986 |
Effects of phenobarbital on early intellectual and behavioral development: a concordant twin case study.
Topics: Child Behavior; Diseases in Twins; Humans; Infant; Intelligence; Phenobarbital; Seizures, Febrile | 1987 |
Management of febrile seizures in a developing country.
Topics: Child; Child, Preschool; Developing Countries; Humans; Infant; Medicine, Ayurvedic; Medicine, Tradit | 1987 |
Carbamazepine in febrile seizures.
Topics: Carbamazepine; Humans; Infant; Phenobarbital; Seizures, Febrile | 1985 |
Recurrence of febrile convulsions and phenobarbital treatment.
Topics: Child; Humans; Phenobarbital; Recurrence; Risk; Seizures, Febrile | 1985 |
[Convulsive crises in childhood].
Topics: Clonazepam; Crying; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Mi | 1985 |