Page last updated: 2024-11-02

phenobarbital and Seizures, Febrile

phenobarbital has been researched along with Seizures, Febrile in 126 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Seizures, Febrile: Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)

Research Excerpts

ExcerptRelevanceReference
" A 3-year-old boy developed alopecia areata (AA) universalis in the convalescent status of phenobarbital-induced AHS, compatible to the evidences of increased lymphocyte proliferation and increased dead cells percentages while his peripheral blood mononuclear cells were incubated with phenobarbital."7.75Alopecia areata universalis after phenobarbital-induced anti-convulsant hypersensitivity syndrome. ( Chen, ST; Hsiao, PF; Hsieh, MY; Huang, JL; Huang, YL; Kuo, HC; Lee, WI; Sheen, JM; Yang, KD; Yu, HR, 2009)
"They conclude that epilepsy has a presentation rate of 9,6% in patients with previous febrile seizures, having the highest risk when they show previous familial seizures, neonatal pathology and altered EEG after the first febrile convulsion."5.26[Epilepsy after febrile seizures. Predisposing factors and role of phenobarbital in its prophylaxis (author's transl)]. ( Díez, JM; Palencia Luances, R; Sánchez-Villares, S; Tresierra, F, 1981)
"Of 290 children with an initial febrile convulsion, 216 met Livingston's criteria for a "simple" febrile convulsion and 74 for "epilepsy triggered by fever."5.26Effectiveness of daily phenobarbital in the prevention of febrile seizure recurrences in "simple" febrile convulsions and "epilepsy triggered by fever". ( Wolf, SM, 1977)
" Intermittent diazepam prophylaxis at times of fever may or may not reduce the recurrence rate significantly, but there is no data to suggest that it improves the long-term outcome, as compared with short-term seizure control, in terms of IQ, cognition, academic progress, motor control, and subsequent epilepsy."4.81[Febrile convulsions, Treatment and prognosis]. ( Knudsen, FU, 2001)
" A 3-year-old boy developed alopecia areata (AA) universalis in the convalescent status of phenobarbital-induced AHS, compatible to the evidences of increased lymphocyte proliferation and increased dead cells percentages while his peripheral blood mononuclear cells were incubated with phenobarbital."3.75Alopecia areata universalis after phenobarbital-induced anti-convulsant hypersensitivity syndrome. ( Chen, ST; Hsiao, PF; Hsieh, MY; Huang, JL; Huang, YL; Kuo, HC; Lee, WI; Sheen, JM; Yang, KD; Yu, HR, 2009)
" The administration of daily phenobarbital did not reduce the frequency of epilepsy, in spite of a significant reduction in the incidence of recurrent febrile seizures."3.67Epilepsy and mental retardation following febrile seizures in childhood. ( Forsythe, A; Wolf, SM, 1989)
"Children with simple febrile convulsions were randomly allocated to receive either phenobarbitone or placebo."2.67Role of phenobarbitone in preventing recurrence of febrile convulsions. ( Ahamed, S; Banu, K; Kamala, KG; Krishnamurthy, PV; Thilothammal, N, 1993)
"Phenytoin was an ineffective prophylactic agent."2.65Placebo-controlled study of phenobarbitone and phenytoin in the prophylaxis of febrile convulsions. ( Bacon, CJ; Hierons, AM; Mucklow, JC; Rawlins, MD; Webb, JK; Weightman, D, 1981)
" They were subsequently followed up as outpatients, and Phenobarbital and sodium valproate levels were measured regularly to ascertain compliance with the treatment and to adjust the dosage accordingly."2.65Prevention of recurrent febrile convulsions--a randomized therapeutic assay: sodium valproate, phenobarbital and placebo. ( Gilly, R; Mamelle, JC; Mamelle, N; Plasse, JC; Revol, M, 1984)
" Twelve hours later and then every 24 hours until the fever had subsided the dosage was 5 mg/kg orally or intramuscularly."2.65[Phenobarbital in febrile convulsions of children (author's transl)]. ( Lagenstein, I; Sternowsky, HJ, 1981)
" The dosage was phenobarbitone 3-6 mg/kg per day; sodium valproate 30-60 mg/kg per day."2.65Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions. Comparison by a double-blind trial. ( Bower, B; Ngwane, E, 1980)
"New convulsions were of similar duration and severity in both groups."2.64Prophylactic diazepam or phenobarbitone in febrile convulsions: a prospective, controlled study. ( Knudsen, FU; Vestermark, S, 1978)
"13% had seizures which were either lateralized or longer than ten minutes."2.64The value of phenobarbital in the child who has had a single febrile seizure: a controlled prospective study. ( Carr, A; Dale, EP; Davidson, S; Davis, DC; Forsythe, A; Goldenberg, ED; Hanson, R; Lulejian, GA; Nelson, MA; Treitman, P; Weinstein, A; Wolf, SM, 1977)
"Recurrences are common."2.42[Febrile seizures--an update]. ( Püst, B, 2004)
"Febrile seizures are the most common seizure disorder in childhood, occurring in 2-5% of children."2.41Treatment of children with simple febrile seizures: the AAP practice parameter. American Academy of Pediatrics. ( Baumann, RJ; Duffner, PK, 2000)
"The risk of recurrences was significantly lower in children receiving continuous phenobarbital therapy than placebo (odds ratio 0."2.40A meta-analytic review of the preventive treatment of recurrences of febrile seizures. ( Rantala, H; Tarkka, R; Uhari, M, 1997)
"Febrile seizures are common in children."2.37The child with febrile seizures. ( Wright, SW, 1987)
"Febrile seizures are a common occurrence in early childhood and most children who experience them do well."2.36The natural history of febrile seizures. ( Hirtz, DG; Nelson, KB, 1983)
"The flupirtine-treated group showed less impairment in learning and memory and less obvious pathological changes in the brain following RFS compared with the phenobarbital-treated group."1.37Protective effect of the KCNQ activator flupirtine on a model of repetitive febrile seizures. ( He, X; Liu, W; Liu, Y; Peng, B; Wang, H; Wang, Y; Yin, J; Yu, F, 2011)
"Five days later, febrile convulsions were induced by hyperthermal bath (45 Celcius degree)."1.36[Prophylactic efficacy of levetiracetam, valproate or phenobarbital on febrile convulsions in rats]. ( Cheng, M; Huang, Z; Li, SX, 2010)
"Five patients had had several febrile seizures prior to the onset of prefebrile seizures."1.31[Apparently unprovoked seizures precipitated by prefebrile condition]. ( Hattori, H; Kato, T; Minamiura, Y; Murakami, M; Nakajima, T, 2000)
"The families of 42 children with febrile seizures were recruited after pediatric or neuropediatric consultation."1.31Treatment of febrile seizures: the influence of treatment efficacy and side-effect profile on value to parents. ( Camfield, CS; Camfield, PR; Dooley, JM; Gordon, KE; MacSween, J, 2001)
"Simple febrile seizures that occur in children ages 6 months to 5 years are common events with few adverse outcomes."1.30Technical report: treatment of the child with simple febrile seizures. ( Baumann, RJ, 1999)
"Complex febrile seizures, affecting an estimated 5000 children in Illinois, were treated with phenobarbital by 90% of respondents, and therapy was continued for an average of 2 years."1.28Management of febrile seizures: current concepts and recommendations for phenobarbital and the electroencephalogram. ( Millichap, JG, 1991)
"Only when the epilepsy is uncontrolled despite high plasma concentrations which cannot be raised because of side effects, a second drug should be given."1.27[Pharmacotherapy of epilepsy--current problems and controversies]. ( Schmidt, D, 1983)
"Diazepam was found to be as effective as oral phenobarbital in the prevention of new febrile seizures."1.27[Continuous oral phenobarbital or intermittent rectal diazepam for the prevention of febrile convulsions]. ( Campos-Castelló, J; Careaga Maldonado, J; Oliete García, F, 1984)
"Percentage of recurrences in phenobarbital treated cases (4 +/- 0,6 mg/Kg/d) was 18,67%, versus 55,89% in untreated children (p less than 0."1.27[Efficacy and failure of phenobarbital in the prevention of febrile convulsions. Importance of familial antecedents]. ( Blanco, A; Cilleruelo, ML; Palencia, R; Tresierra, F, 1983)
"In the analysis of 128 patients with febrile convulsions, we identified hazards not encountered in the western world, which could alter the ultimate management of the child."1.27Management of febrile seizures in a developing country. ( Canagarayar, UT; Soysa, P, 1987)
"When phenobarbital was withdrawn, the treated twin's behavior showed immediate improvement."1.27Effects of phenobarbital on early intellectual and behavioral development: a concordant twin case study. ( Byrne, JM; Camfield, PR; Clark-Touesnard, M; Hondas, BJ, 1987)
" The plasma level/dosage ratio has been found to have a highly significant correlation with the age of the patient both for dosage in mg/kg and in mg/m2."1.26Correlation between age and plasma level/dosage ratio for phenobarbital in infants and children. ( Nino, LM; Principi, N; Rossi, LN, 1979)
"The risk of another febrile convulsion is approximately 30%."1.26Continuous phenobarbital treatment after a 'simple febril convulsion'. ( Pollack, MA, 1978)
"in 33 patients."1.26Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions. ( Minagawa, K; Miura, H, 1981)
"Of 290 children with an initial febrile convulsion, 216 met Livingston's criteria for a "simple" febrile convulsion and 74 for "epilepsy triggered by fever."1.26Effectiveness of daily phenobarbital in the prevention of febrile seizure recurrences in "simple" febrile convulsions and "epilepsy triggered by fever". ( Wolf, SM, 1977)
"Phenobarbital has been shown to offer effective prophylaxis against childhood febrile convulsions."1.26Sodium valproate versus phenobarbital in the prophylactic treatment of febrile convulsions in childhood. ( Lee, K; Melchior, JC, 1981)
" Thus in adequate dosage both phenobarbitone and valproic acid were significantly better than no treatment in preventing febrile convulsions (p less than 0."1.26Successful prophylaxis against febrile convulsions with valproic acid or phenobarbitone. ( Smith, JA; Wallace, SJ, 1980)
"They conclude that epilepsy has a presentation rate of 9,6% in patients with previous febrile seizures, having the highest risk when they show previous familial seizures, neonatal pathology and altered EEG after the first febrile convulsion."1.26[Epilepsy after febrile seizures. Predisposing factors and role of phenobarbital in its prophylaxis (author's transl)]. ( Díez, JM; Palencia Luances, R; Sánchez-Villares, S; Tresierra, F, 1981)
" Saliva samples were easily obtained and the measured concentrations were a valuable guide to drug dosage during the treatment period."1.26Monitoring of phenobarbitone and phenytoin therapy in small children by salivary samples. ( Bacon, CJ; Hierons, AM; Mucklow, JC; Rawlins, MD; Webb, JK, 1981)
"A Consensus Development Conference on Febrile Seizures was held at the National Institutes of Health in USA in May 1980."1.26["Fever convulsions" in children. Current viewpoints on diagnosis, therapy and prognosis]. ( Helwig, H; Staudt, F, 1982)
"Febrile convulsions occur in 3."1.26Febrile convulsions. ( Curry, HB, 1980)

Research

Studies (126)

TimeframeStudies, this research(%)All Research%
pre-199098 (77.78)18.7374
1990's15 (11.90)18.2507
2000's8 (6.35)29.6817
2010's3 (2.38)24.3611
2020's2 (1.59)2.80

Authors

AuthorsStudies
Polavarapu, A1
Moshé, SL1
Renda, R1
Yüksel, D1
Gürer, YKY1
Wolski, TP1
Blasick, S1
Blackford, MG1
Huang, YL1
Hsieh, MY1
Hsiao, PF1
Sheen, JM1
Yu, HR1
Kuo, HC1
Chen, ST1
Huang, JL1
Yang, KD1
Lee, WI1
Cheng, M1
Huang, Z1
Li, SX1
Yu, F1
Liu, Y1
Wang, Y1
Yin, J1
Wang, H1
Liu, W1
Peng, B1
He, X1
MILLICHAP, JG2
ALEDORT, LM1
MADSEN, JA1
Masuko, AH1
Castro, AA1
Santos, GR1
Atallah, AN1
do Prado, LB1
de Carvalho, LB1
do Prado, GF1
Püst, B1
Bacon, CJ3
Hierons, AM3
Mucklow, JC2
Webb, JK3
Rawlins, MD3
Weightman, D1
Stephenson, JB1
Hirtz, DG3
Nelson, KB2
Antony, JH1
Hawke, SH1
Johnson, DD1
Crawford, KD1
Crawford, RD1
Escorihuela, R1
Sandiumenge, J1
Schmidt, D1
Herranz, JL1
Armijo, JA1
Arteaga, R1
Olson, JE1
Scher, MS1
Holtzman, D1
Mamelle, N2
Mamelle, JC2
Plasse, JC2
Revol, M2
Gilly, R2
Gram, L1
Bentsen, KD1
Zanini, R1
Caminiti, A1
Bollati, A1
Focarile, F1
Rondanini, GF1
Grasso, E1
Oliete García, F1
Campos-Castelló, J1
Careaga Maldonado, J1
Palencia, R1
Cilleruelo, ML1
Tresierra, F2
Blanco, A1
Wallace, SJ3
Haddock, ST1
Smith, JA2
Ngwane, E1
Bower, B1
Cowen, J1
Harris, F1
Masala, A1
Meloni, T1
Alagna, S1
Rovasio, PP1
Mele, G1
Franca, V1
Pearce, JL2
Giles, HM1
Addy, DP2
Lee, K1
Melchior, JC1
Minagawa, K1
Miura, H1
Staudt, F1
Helwig, H1
Nurchi, AM1
Cappai, A1
Repetto, C1
Byrge, H1
Kragstrup, J1
Lund, HT1
Camfield, PR5
Camfield, CS4
Tibbles, JA1
Pilgaard, S1
Hansen, FJ1
Paerregaard, P1
Nakamura, M1
Kajitani, T1
Cranage, JD1
Wolf, SM7
Forsythe, A4
Stunden, AA1
Friedman, R1
Diamond, H1
Palencia Luances, R1
Díez, JM1
Sánchez-Villares, S1
Curry, HB1
Shapiro, SH2
Cummings, C2
Valman, HB1
Schain, RJ1
Sternowsky, HJ1
Lagenstein, I2
Coker, SB1
Domizio, S1
Verrotti, A1
Ramenghi, LA1
Sabatino, G1
Morgese, G1
Thilothammal, N1
Krishnamurthy, PV1
Kamala, KG1
Ahamed, S1
Banu, K1
Rantala, H1
Tarkka, R1
Uhari, M1
Cavazzuti, GB1
Baumann, RJ2
Sulzbacher, S1
Farwell, JR2
Temkin, N1
Lu, AS1
Minamiura, Y1
Hattori, H1
Nakajima, T1
Murakami, M1
Kato, T1
Duffner, PK1
Knudsen, FU4
Gordon, KE1
Dooley, JM1
MacSween, J1
Autret-Leca, E1
Ployet, JL1
Jonville-Bera, AP1
Sharman, JR1
Forster, RM1
Trubuhovich, RV1
Julien, RM2
Fowler, GW2
Vestermark, S2
Fishman, MA2
Livingston, S2
Pauli, LL2
Pruce, I2
Kramer, II2
Chaplin, S1
Doyle, AB1
Borgheresi, S1
Luti, E1
Buti Cossi, D1
Mecherini, L1
Bardini, MR1
Burgio, E1
Ciampi, C1
Benocci, M1
Massai, S1
Lini, M1
Grifi, G1
Valenza, T1
Swanson, PD1
Benítez, J1
Dalhqvist, R1
Rossi, LN1
Nino, LM1
Principi, N1
MacDonald, JT1
Pollack, MA1
Ellsworth, A1
Thompson, FL1
Freeman, JM2
Pascoe, JM1
Schnitzker, WF1
Ounsted, C1
Gorman, RJ1
Snead, OC1
Carr, A1
Davis, DC1
Davidson, S1
Dale, EP1
Goldenberg, ED1
Hanson, R1
Lulejian, GA1
Nelson, MA1
Treitman, P1
Weinstein, A1
Jalling, B1
Baldellou Vázquez, A1
Gomá Brufau, A1
Vargas Torcal, F1
Pastor Mourón, I1
Ros Mar, L1
Ferrández Longás, A1
Tomasi, LG1
Wässer, S2
Wässer, R2
Vajnorský, J1
Gutová, M1
Ulrychová, Z1
Vigevano, F1
Di Capua, M1
Fusco, L1
Ricci, S1
Sebastianelli, R1
Lucchini, P1
Placencia, M1
Suarez, J1
Crespo, F1
Sander, JW1
Shorvon, SD1
Ellison, RH1
Cascante, SM1
Ehrhardt, P1
Miceli Sopo, S1
Pesaresi, MA1
Celestini, E1
Stabile, A1
Lee, YJ1
Sulzbacher, SI1
Ellenberg, JH1
McKinlay, I1
Newton, R1
Saw, AH1
Ho, L1
Lim, KW1
Cheng, HK1
Rosman, NP1
Newton, RW1
Rohmann, E1
Sengbusch, S1
Hobusch, D1
Popp, K1
Schwebke, D1
Wright, SW1
Huang, SW1
Somasundram, P1
Tan, CL1
Byrne, JM1
Clark-Touesnard, M1
Hondas, BJ1
Canagarayar, UT1
Soysa, P1
Vining, EP1
Giroud, M1
Dumas, R1
Rothe, B1
Herranz Fernández, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An MRI Ancillary Study of a Malaria Fever Randomized Controlled Trial (RCT)[NCT05746819]256 participants (Anticipated)Observational2021-01-02Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for phenobarbital and Seizures, Febrile

ArticleYear
Intermittent diazepam and continuous phenobarbital to treat recurrence of febrile seizures: a systematic review with meta-analysis.
    Arquivos de neuro-psiquiatria, 2003, Volume: 61, Issue:4

    Topics: Anticonvulsants; Diazepam; Follow-Up Studies; Humans; Odds Ratio; Phenobarbital; Placebos; Randomize

2003
[Febrile seizures--an update].
    Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege, 2004, Volume: 23, Issue:8

    Topics: Administration, Oral; Administration, Rectal; Age Factors; Analgesics, Non-Narcotic; Anticonvulsants

2004
The natural history of febrile seizures.
    Annual review of medicine, 1983, Volume: 34

    Topics: Animals; Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Infant

1983
[Use of phenobarbital in febrile convulsive crisis].
    Anales espanoles de pediatria, 1983, Volume: 18, Issue:2

    Topics: Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Nervous System Diseases; Phenobarbital; Recurr

1983
A meta-analytic review of the preventive treatment of recurrences of febrile seizures.
    The Journal of pediatrics, 1997, Volume: 131, Issue:6

    Topics: Anticonvulsants; Chi-Square Distribution; Child; Diazepam; Drug Administration Schedule; Fever; Huma

1997
Treatment of children with simple febrile seizures: the AAP practice parameter. American Academy of Pediatrics.
    Pediatric neurology, 2000, Volume: 23, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combin

2000
[Febrile convulsions, Treatment and prognosis].
    Ugeskrift for laeger, 2001, Feb-19, Volume: 163, Issue:8

    Topics: Analgesics, Non-Narcotic; Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phe

2001
Febrile seizures: the treatment controversy.
    The Journal of pediatrics, 1979, Volume: 94, Issue:2

    Topics: Child; Epilepsy; Humans; Nervous System Diseases; Phenobarbital; Phenytoin; Recurrence; Seizures; Se

1979
Febrile convulsions: diagnosis, treatment, and prognosis.
    Pediatric annals, 1979, Volume: 8, Issue:3

    Topics: Child; Epilepsy; Humans; Infant; Intellectual Disability; Intelligence; Meningitis; Phenobarbital; P

1979
[Prevention of recurrences and of epilepsy in febrile convulsions. Protocol of the Pediatric Clinic of the Florence and preliminary results].
    Minerva pediatrica, 1979, Nov-30, Volume: 31, Issue:22

    Topics: Age Factors; Child; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phenobarbital; Recurrence;

1979
Phenobarbitone and febrile convulsions.
    Archives of disease in childhood, 1990, Volume: 65, Issue:9

    Topics: Humans; Infant; Intelligence; Phenobarbital; Seizures, Febrile; Time Factors; Valproic Acid

1990
Febrile seizures.
    Emergency medicine clinics of North America, 1987, Volume: 5, Issue:4

    Topics: Child; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencephalography; Epilepsy; Female

1987
The child with febrile seizures.
    American family physician, 1987, Volume: 36, Issue:5

    Topics: Child, Preschool; Diagnosis, Differential; Diazepam; Fever; Humans; Infant; Phenobarbital; Prognosis

1987
Seizures which are not epilepsy.
    Pediatric annals, 1985, Volume: 14, Issue:11

    Topics: Child, Preschool; Epilepsies, Partial; Fever; Humans; Hypocalcemia; Hypoglycemia; Infant; Infant, Ne

1985

Trials

23 trials available for phenobarbital and Seizures, Febrile

ArticleYear
Placebo-controlled study of phenobarbitone and phenytoin in the prophylaxis of febrile convulsions.
    Lancet (London, England), 1981, Sep-19, Volume: 2, Issue:8247

    Topics: Age Factors; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbi

1981
Phenobarbital compared with carbamazepine in prevention of recurrent febrile convulsions. A double-blind study.
    American journal of diseases of children (1960), 1983, Volume: 137, Issue:9

    Topics: Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Inf

1983
Prevention of recurrent febrile convulsions--a randomized therapeutic assay: sodium valproate, phenobarbital and placebo.
    Neuropediatrics, 1984, Volume: 15, Issue:1

    Topics: Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Electroencephalography

1984
Controlled and comparative trials of valproate performed in Europe and Asia.
    Epilepsia, 1984, Volume: 25 Suppl 1

    Topics: Adolescent; Adult; Asia; Carbamazepine; Child; Clinical Trials as Topic; Epilepsy; Europe; Humans; P

1984
Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions. Comparison by a double-blind trial.
    Archives of disease in childhood, 1980, Volume: 55, Issue:3

    Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Random A

1980
[Efficacy of sodium dipropylacetate compared with phenobarbital and placebo in the prevention of recurrence of febrile convulsions].
    Pediatrie, 1982, Volume: 37, Issue:6

    Topics: Child, Preschool; Clinical Trials as Topic; Female; Humans; Infant; Male; Phenobarbital; Placebos; R

1982
Behavioural effects of phenobarbitone and phenytoin in small children.
    Archives of disease in childhood, 1981, Volume: 56, Issue:11

    Topics: Child Behavior Disorders; Female; Hospitalization; Humans; Infant; Male; Phenobarbital; Phenytoin; S

1981
Long-term effect of phenobarbital on cognitive function in children with febrile convulsions.
    Pediatrics, 1981, Volume: 68, Issue:6

    Topics: Child; Child, Preschool; Cognition; Female; Humans; Male; Patient Compliance; Phenobarbital; Psychol

1981
The first febrile seizure--antipyretic instruction plus either phenobarbital or placebo to prevent recurrence.
    The Journal of pediatrics, 1980, Volume: 97, Issue:1

    Topics: Child, Preschool; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Placebos; Seizur

1980
[Phenobarbital in febrile convulsions of children (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, Jan-09, Volume: 106, Issue:2

    Topics: Administration, Oral; Child, Preschool; Humans; Infant; Injections, Intramuscular; Phenobarbital; Se

1981
Role of phenobarbitone in preventing recurrence of febrile convulsions.
    Indian pediatrics, 1993, Volume: 30, Issue:5

    Topics: Child; Child, Preschool; Double-Blind Method; Drug Tolerance; Epilepsies, Partial; Epilepsy, Tonic-C

1993
Prevention of febrile convulsions with dipropylacetate (Depakine).
    Epilepsia, 1975, Volume: 16, Issue:4

    Topics: Anticonvulsants; Child, Preschool; Humans; Phenobarbital; Primidone; Seizures, Febrile; Valproic Aci

1975
Late cognitive effects of early treatment with phenobarbital.
    Clinical pediatrics, 1999, Volume: 38, Issue:7

    Topics: Child; Humans; Intelligence; Intelligence Tests; Male; Neurobehavioral Manifestations; Phenobarbital

1999
[Prevention of febrile convulsions with diazepam or phenemal. A prospective controlled study].
    Ugeskrift for laeger, 1978, May-01, Volume: 140, Issue:18

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Humans; Infant; Phenobarbital; Prospect

1978
Prophylactic diazepam or phenobarbitone in febrile convulsions: a prospective, controlled study.
    Archives of disease in childhood, 1978, Volume: 53, Issue:8

    Topics: Child, Preschool; Clinical Trials as Topic; Diazepam; Female; Humans; Infant; Male; Phenobarbital; P

1978
Side effects of phenobarbital in toddlers; behavioral and cognitive aspects.
    The Journal of pediatrics, 1979, Volume: 95, Issue:3

    Topics: Child Behavior Disorders; Child, Preschool; Clinical Trials as Topic; Cognition Disorders; Dose-Resp

1979
The value of phenobarbital in the child who has had a single febrile seizure: a controlled prospective study.
    Pediatrics, 1977, Volume: 59, Issue:3

    Topics: Child, Preschool; Female; Humans; Infant; Male; Patient Compliance; Phenobarbital; Prospective Studi

1977
Plasma-diazepam in infants after rectal administration in solution and by suppository.
    Acta paediatrica Scandinavica, 1977, Volume: 66, Issue:5

    Topics: Child, Preschool; Diazepam; Humans; Infant; Phenobarbital; Rectum; Seizures, Febrile; Solutions; Sup

1977
A large-scale study of epilepsy in Ecuador: methodological aspects.
    Neuroepidemiology, 1992, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Cross-Sectional Studies; Developing Count

1992
Short-term prophylaxis of febrile convulsions.
    Acta paediatrica Scandinavica, 1991, Volume: 80, Issue:2

    Topics: Child; Child, Preschool; Diazepam; Female; Humans; Infant; Male; Phenobarbital; Prospective Studies;

1991
Phenobarbital for febrile seizures--effects on intelligence and on seizure recurrence.
    The New England journal of medicine, 1990, Feb-08, Volume: 322, Issue:6

    Topics: Child, Preschool; Cognition; Female; Humans; Infant; Intelligence; Male; Phenobarbital; Randomized C

1990
Intention to treat febrile convulsions with rectal diazepam, valproate or phenobarbitone.
    Developmental medicine and child neurology, 1989, Volume: 31, Issue:5

    Topics: Administration, Rectal; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Male; Phenobarbit

1989
Randomised controlled trials of phenobarbitone and valproate in febrile convulsions.
    Archives of disease in childhood, 1988, Volume: 63, Issue:10

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Phenobarbital; Random Allocation;

1988

Other Studies

89 other studies available for phenobarbital and Seizures, Febrile

ArticleYear
50 Years Ago in TheJournalofPediatrics: Intermittent Phenobarbital Treatment to Prevent Recurrent Febrile Seizures.
    The Journal of pediatrics, 2021, Volume: 233

    Topics: Anticonvulsants; History, 20th Century; Humans; Pediatrics; Periodicals as Topic; Phenobarbital; Rec

2021
Evaluation of Patients With Febrile Seizure: Risk Factors, Reccurence, Treatment and Prognosis.
    Pediatric emergency care, 2020, Volume: 36, Issue:4

    Topics: Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Female; Fever; Humans; Infant;

2020
The Case of the Previously Shaky, Unimmunized, Itchy Infant With Rash and Pancytopenia.
    Clinical pediatrics, 2016, Volume: 55, Issue:14

    Topics: Anticonvulsants; Antipyretics; Drug Hypersensitivity Syndrome; Exanthema; Humans; Infant; Male; Panc

2016
Alopecia areata universalis after phenobarbital-induced anti-convulsant hypersensitivity syndrome.
    Immunological investigations, 2009, Volume: 38, Issue:5

    Topics: Alopecia Areata; Anticonvulsants; Child, Preschool; Drug Hypersensitivity; Humans; Male; Phenobarbit

2009
[Prophylactic efficacy of levetiracetam, valproate or phenobarbital on febrile convulsions in rats].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2010, Volume: 12, Issue:7

    Topics: Animals; Anticonvulsants; Levetiracetam; Male; Phenobarbital; Piracetam; Rats; Recurrence; Seizures,

2010
Protective effect of the KCNQ activator flupirtine on a model of repetitive febrile seizures.
    Epilepsy research, 2011, Volume: 97, Issue:1-2

    Topics: Aminopyridines; Analgesics; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography

2011
A critical evaluation of therapy of febrile seizures.
    The Journal of pediatrics, 1960, Volume: 56

    Topics: Child; Fever; Humans; Hydantoins; Infant; Phenobarbital; Seizures; Seizures, Febrile

1960
Prophylaxis of febrile convulsions.
    Lancet (London, England), 1981, Oct-24, Volume: 2, Issue:8252

    Topics: Humans; Infant; Phenobarbital; Phenytoin; Random Allocation; Seizures, Febrile

1981
Phenobarbitone in the prophylaxis of febrile convulsions.
    Lancet (London, England), 1981, Nov-07, Volume: 2, Issue:8254

    Topics: Humans; Phenobarbital; Recurrence; Seizures, Febrile

1981
Febrile seizures in epileptic chicks: the effects of phenobarbital, phenytoin and valproate.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1983, Volume: 10, Issue:2

    Topics: Animals; Chickens; Disease Models, Animal; Phenobarbital; Phenytoin; Reaction Time; Seizures, Febril

1983
[Pharmacotherapy of epilepsy--current problems and controversies].
    Fortschritte der Neurologie-Psychiatrie, 1983, Volume: 51, Issue:11

    Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy,

1983
Effectiveness and toxicity of phenobarbital, primidone, and sodium valproate in the prevention of febrile convulsions, controlled by plasma levels.
    Epilepsia, 1984, Volume: 25, Issue:1

    Topics: Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Male; Phenobarbital; Prim

1984
Effects of anticonvulsants on hyperthermia-induced seizures in the rat pup.
    Epilepsia, 1984, Volume: 25, Issue:1

    Topics: Animals; Animals, Newborn; Behavior, Animal; Body Temperature; Differential Threshold; Disease Model

1984
[Effects of phenobarbital on thyroid function in childhood. Iatrogenic TBG deficiency].
    Minerva pediatrica, 1984, May-31, Volume: 36, Issue:10

    Topics: Child; Child, Preschool; Female; Humans; Iatrogenic Disease; Infant; Male; Phenobarbital; Seizures,

1984
[Continuous oral phenobarbital or intermittent rectal diazepam for the prevention of febrile convulsions].
    Anales espanoles de pediatria, 1984, Volume: 20, Issue:8

    Topics: Administration, Oral; Child, Preschool; Diazepam; Female; Humans; Infant; Longitudinal Studies; Male

1984
[Efficacy and failure of phenobarbital in the prevention of febrile convulsions. Importance of familial antecedents].
    Anales espanoles de pediatria, 1983, Volume: 18, Issue:2

    Topics: Age Factors; Epilepsy; Female; Fetal Hypoxia; Humans; Male; Phenobarbital; Pregnancy; Recurrence; Se

1983
Febrile convulsions: their significance for later intellectual development and behaviour.
    Journal of child psychology and psychiatry, and allied disciplines, 1984, Volume: 25, Issue:1

    Topics: Child; Child Behavior Disorders; Child Development; Child, Preschool; Female; Follow-Up Studies; Hum

1984
Drug treatment of recurrent febrile seizures.
    American journal of diseases of children (1960), 1984, Volume: 138, Issue:5

    Topics: Antacids; Child; Humans; Phenobarbital; Recurrence; Seizures, Febrile

1984
Successful prophylaxis against febrile convulsions with valproic acid or phenobarbitone.
    British medical journal, 1980, Feb-09, Volume: 280, Issue:6211

    Topics: Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Recurrence; Seizures; Seizures, Febri

1980
Prophylaxis against febrile convulsions.
    British medical journal, 1980, Mar-01, Volume: 280, Issue:6214

    Topics: Child; Humans; Phenobarbital; Seizures; Seizures, Febrile; Valproic Acid

1980
Prophylaxis against febrile convulsions.
    British medical journal, 1980, Apr-19, Volume: 280, Issue:6221

    Topics: Child, Preschool; Diagnosis, Differential; Epilepsy; Humans; Infant; Phenobarbital; Seizures; Seizur

1980
Pituitary responsiveness to gonadotrophin-releasing and thyrotrophin-releasing hormones in children receiving phenobarbitone.
    British medical journal, 1980, Nov-01, Volume: 281, Issue:6249

    Topics: Child, Preschool; Follicle Stimulating Hormone; Humans; Infant; Long-Term Care; Luteinizing Hormone;

1980
Prevention of simple febrile convulsions.
    Archives of disease in childhood, 1980, Volume: 55, Issue:10

    Topics: Child; Humans; Phenobarbital; Seizures; Seizures, Febrile; Valproic Acid

1980
Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions.
    Archives of disease in childhood, 1980, Volume: 55, Issue:8

    Topics: Humans; Infant; Infant, Newborn; Phenobarbital; Recurrence; Seizures; Seizures, Febrile; Valproic Ac

1980
Prophylaxis and febrile convulsions.
    Archives of disease in childhood, 1981, Volume: 56, Issue:2

    Topics: Child; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phenobarbital; Recurrence; Seizures; Se

1981
Febrile convulsions: long-term treatment.
    British medical journal (Clinical research ed.), 1981, Feb-28, Volume: 282, Issue:6265

    Topics: Anticonvulsants; Child; Child, Preschool; Humans; Infant; Phenobarbital; Prognosis; Recurrence; Seiz

1981
Sodium valproate versus phenobarbital in the prophylactic treatment of febrile convulsions in childhood.
    European journal of pediatrics, 1981, Volume: 137, Issue:2

    Topics: Child Behavior Disorders; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Seizures, F

1981
Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions.
    Brain & development, 1981, Volume: 3, Issue:4

    Topics: Child, Preschool; Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Primidone; Recurr

1981
Febrile convulsions: intellectual progress in relation to anticonvulsant therapy and to recurrence of fits.
    Archives of disease in childhood, 1982, Volume: 57, Issue:2

    Topics: Child Development; Child, Preschool; Humans; Infant; Intelligence; Intelligence Tests; Phenobarbital

1982
["Fever convulsions" in children. Current viewpoints on diagnosis, therapy and prognosis].
    Fortschritte der Medizin, 1982, Jun-24, Volume: 100, Issue:24

    Topics: Child, Preschool; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Parents; Phenobarbita

1982
[Simple or benign febrile convulsions. Clinical and statistical evaluation].
    Minerva pediatrica, 1982, Feb-28, Volume: 34, Issue:4

    Topics: Age Factors; Child; Humans; Phenobarbital; Seizures, Febrile; Sex Factors

1982
[Continuing treatment with phenemal in prevention of febrile convulsions. A report of children with the first febrile convulsions treated during 2 years].
    Ugeskrift for laeger, 1982, Apr-12, Volume: 144, Issue:15

    Topics: Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Seizures, Febrile

1982
Carbamazepine does not prevent febrile seizures in phenobarbital failures.
    Neurology, 1982, Volume: 32, Issue:3

    Topics: Carbamazepine; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Recurrence; Seizures,

1982
Prophylaxis against febrile convulsions with phenobarbital. A 3-year prospective investigation.
    Acta paediatrica Scandinavica, 1981, Volume: 70, Issue:1

    Topics: Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Male; Phenobarbital; Prospective

1981
A study on serum concentration of phenobarbital in epileptic children and children with febrile convulsions.
    Folia psychiatrica et neurologica japonica, 1980, Volume: 34, Issue:3

    Topics: Child; Epilepsy; Humans; Phenobarbital; Seizures; Seizures, Febrile

1980
Monitoring of phenobarbitone and phenytoin therapy in small children by salivary samples.
    Therapeutic drug monitoring, 1981, Volume: 3, Issue:3

    Topics: Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Phenytoin; Saliva; Seizures, Febril

1981
[Epilepsy after febrile seizures. Predisposing factors and role of phenobarbital in its prophylaxis (author's transl)].
    Anales espanoles de pediatria, 1981, Volume: 15, Issue:4

    Topics: Age Factors; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Infant; Infant, New

1981
Febrile convulsions.
    American family physician, 1980, Volume: 21, Issue:2

    Topics: Child, Preschool; Epilepsy; Humans; Infant; Male; Phenobarbital; Prognosis; Seizures; Seizures, Febr

1980
The first year of life. Convulsions in the older infant.
    British medical journal, 1980, Apr-26, Volume: 280, Issue:6222

    Topics: Diazepam; First Aid; Humans; Hyaluronoglucosaminidase; Infant; Paraldehyde; Phenobarbital; Seizures;

1980
Febrile seizures: long-term management of children with fever-associated seizures. Summary of an NIH consensus statement.
    British medical journal, 1980, Jul-26, Volume: 281, Issue:6235

    Topics: Child, Preschool; Diazepam; Epilepsy; Fever; Humans; Infant; Phenobarbital; Risk; Seizures; Seizures

1980
Phenobarbital in neurologically handicapped children.
    The Journal of pediatrics, 1981, Volume: 98, Issue:1

    Topics: Brain Damage, Chronic; Child; Humans; Intellectual Disability; Nervous System Diseases; Phenobarbita

1981
Childhood febrile convulsions.
    Lancet (London, England), 1994, Feb-19, Volume: 343, Issue:8895

    Topics: Child; Epilepsy; Hippocampus; Humans; Phenobarbital; Sclerosis; Seizures, Febrile

1994
Anti-epileptic therapy and behaviour disturbances in children.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1993, Volume: 9, Issue:5

    Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Chi

1993
Jury finds pharmacy's misfilling of prescription caused child's brain damage.
    Journal of child neurology, 1999, Volume: 14, Issue:4

    Topics: Brain Damage, Chronic; California; Child; Female; Humans; Liability, Legal; Medication Errors; Pharm

1999
Technical report: treatment of the child with simple febrile seizures.
    Pediatrics, 1999, Volume: 103, Issue:6

    Topics: Analgesics, Non-Narcotic; Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phe

1999
[Apparently unprovoked seizures precipitated by prefebrile condition].
    No to hattatsu = Brain and development, 2000, Volume: 32, Issue:1

    Topics: Anticonvulsants; Body Temperature; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Humans; In

2000
Treatment of febrile seizures: the influence of treatment efficacy and side-effect profile on value to parents.
    Pediatrics, 2001, Volume: 108, Issue:5

    Topics: Adult; Anticonvulsants; Anxiety; Attitude; Child, Preschool; Diazepam; Educational Status; Female; H

2001
[Treatment of febrile convulsions].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2002, Volume: 9, Issue:1

    Topics: Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child, Preschool; Diazepam; D

2002
Phenobarbital in the acute management of febrile convulsions.
    Pediatrics, 1977, Volume: 60, Issue:4 Pt 2

    Topics: Child, Preschool; Humans; Infant; Injections, Intramuscular; Phenobarbital; Seizures, Febrile

1977
The initial management of simple febrile seizures.
    The New Zealand medical journal, 1978, Sep-13, Volume: 88, Issue:619

    Topics: Child; Humans; Phenobarbital; Seizures; Seizures, Febrile

1978
A comparative study of the efficacy of newer antiepiletpic drugs on experimentally-induced febrile convulsions.
    Neuropharmacology, 1977, Volume: 16, Issue:11

    Topics: Animals; Anticonvulsants; Body Temperature; Carbamazepine; Clonazepam; Male; Mice; Phenobarbital; Se

1977
Anticonvulsant therapy. Approaches to some common clinical problems.
    Postgraduate medicine, 1979, Volume: 65, Issue:3

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Eth

1979
Continuous phenobarbital treatment after a 'simple febrile convulsion'.
    American journal of diseases of children (1960), 1979, Volume: 133, Issue:2

    Topics: Animals; Child; Epilepsy; Humans; Phenobarbital; Recurrence; Seizures; Seizures, Febrile

1979
[Continuous administration of phenobarbital as prevention of febrile convulsions in children. Critical review].
    Revista clinica espanola, 1979, Jan-31, Volume: 152, Issue:2

    Topics: Child, Preschool; Female; Humans; Infant; Male; Methods; Phenobarbital; Seizures; Seizures, Febrile

1979
Correlation between age and plasma level/dosage ratio for phenobarbital in infants and children.
    Acta paediatrica Scandinavica, 1979, Volume: 68, Issue:3

    Topics: Age Factors; Body Weight; Child; Child, Preschool; Epilepsy; Humans; Infant; Phenobarbital; Seizures

1979
Commentary: side effects of phenobarbital.
    The Journal of pediatrics, 1979, Volume: 95, Issue:3

    Topics: Child, Preschool; Cognition Disorders; Humans; Intelligence; Intelligence Tests; Phenobarbital; Seiz

1979
Febrile convulsions--current controversies.
    Minnesota medicine, 1979, Volume: 62, Issue:6

    Topics: Child, Preschool; Humans; Infant; Infant, Newborn; Phenobarbital; Prognosis; Risk; Seizures; Seizure

1979
Controversies in the treatment of febrile convulsions.
    Neurology, 1979, Volume: 29, Issue:3

    Topics: Child; Epilepsy; Humans; Intelligence; Phenobarbital; Phenytoin; Prognosis; Seizures; Seizures, Febr

1979
Continuous phenobarbital treatment after a 'simple febril convulsion'.
    American journal of diseases of children (1960), 1978, Volume: 132, Issue:1

    Topics: Child; Epilepsy; Humans; Phenobarbital; Seizures; Seizures, Febrile; Time Factors

1978
Phenobarbital for febrile convulsions.
    The Journal of family practice, 1978, Volume: 6, Issue:6

    Topics: Administration, Oral; Child; Humans; Phenobarbital; Seizures; Seizures, Febrile

1978
Behavior disturbance, phenobarbital, and febrile seizures.
    Pediatrics, 1978, Volume: 61, Issue:5

    Topics: Barbiturates; Child Behavior Disorders; Humans; Hyperkinesis; Mephobarbital; Phenobarbital; Recurren

1978
Febrile seizures: an end to confusion.
    Pediatrics, 1978, Volume: 61, Issue:5

    Topics: Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Hyperkinesis; Infant; Infant,

1978
Simple febrile seizures.
    American journal of diseases of children (1960), 1978, Volume: 132, Issue:7

    Topics: Child; Community Participation; Decision Making; Humans; Parents; Phenobarbital; Recurrence; Seizure

1978
'Simple febrile convulsion'.
    American journal of diseases of children (1960), 1978, Volume: 132, Issue:7

    Topics: Humans; Phenobarbital; Recurrence; Seizures; Seizures, Febrile

1978
Phenobarbital and febrile seizures.
    Pediatrics, 1978, Volume: 61, Issue:6

    Topics: Drug Administration Schedule; Humans; Phenobarbital; Recurrence; Seizures; Seizures, Febrile

1978
Preventing febrile convulsions.
    Developmental medicine and child neurology, 1978, Volume: 20, Issue:6

    Topics: Child, Preschool; Diazepam; Humans; Infant; Phenobarbital; Seizures; Seizures, Febrile

1978
Febrile seizures.
    American family physician, 1979, Volume: 19, Issue:1

    Topics: Anticonvulsants; Child; Humans; Phenobarbital; Seizures; Seizures, Febrile

1979
[Phenemal prophylaxis and prognosis].
    Lakartidningen, 1977, Mar-16, Volume: 74, Issue:11

    Topics: Child; Child, Preschool; Epilepsy; Humans; Infant; Phenobarbital; Prognosis; Recurrence; Seizures; S

1977
Effectiveness of daily phenobarbital in the prevention of febrile seizure recurrences in "simple" febrile convulsions and "epilepsy triggered by fever".
    Epilepsia, 1977, Volume: 18, Issue:1

    Topics: Child; Diagnosis, Differential; Epilepsy; Humans; Phenobarbital; Seizures; Seizures, Febrile

1977
Effectiveness of N,N-dimethoxymethyl-phenobarbital (eterobarbital) on febrile seizures.
    Proceedings of the Western Pharmacology Society, 1977, Volume: 20

    Topics: Administration, Oral; Animals; Injections, Intraperitoneal; Male; Mice; Phenobarbital; Seizures; Sei

1977
The effectiveness of phenobarbital in the prevention of recurrent febrile convulsions in children with and without a history of pre-, peri- and postnatal abnormalities.
    Acta paediatrica Scandinavica, 1977, Volume: 66, Issue:5

    Topics: Child; Child, Preschool; Female; Follow-Up Studies; Humans; Obstetric Labor Complications; Phenobarb

1977
[Height alterations and calcium metabolism after prolongated phenobarbital treatment (author's transl)].
    Anales espanoles de pediatria, 1977, Volume: 10, Issue:5

    Topics: Alkaline Phosphatase; Bone Development; Calcium; Growth; Growth Disorders; Humans; Infant; Phenobarb

1977
Seizures in childhood encephalopathy or epilepsy?
    Comprehensive therapy, 1977, Volume: 3, Issue:9

    Topics: Adolescent; Child; Epilepsy; Humans; Metabolic Diseases; Neurologic Examination; Phenobarbital; Prim

1977
[Interval therapy of febrile convulsions for the management of their prognosis. I. Methods and therapeutic advice for interval therapy of febrile convulsions].
    Kinderarztliche Praxis, 1976, Volume: 44, Issue:11

    Topics: Child, Preschool; Epilepsy; Humans; Infant; Periodicity; Phenobarbital; Phenytoin; Recurrence; Seizu

1976
[Interval therapy of febrile convulsions for management of the prognosis. II. Anticonvulsant longtime Fali-Lepsin therapy of complicated febrile convulsions].
    Kinderarztliche Praxis, 1976, Volume: 44, Issue:12

    Topics: Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Phenylpropanolamine; Progno

1976
[Problems in the preventive treatment of repeated febrile convulsions].
    Ceskoslovenska pediatrie, 1976, Volume: 31, Issue:11

    Topics: Child; Child, Preschool; Chronic Disease; Female; Humans; Infant; Male; Phenobarbital; Prognosis; Re

1976
Sixth-month benign familial convulsions.
    Epilepsy research. Supplement, 1992, Volume: 6

    Topics: Electroencephalography; Epilepsies, Partial; Female; Follow-Up Studies; Humans; Infant; Male; Phenob

1992
Phenobarbitone and epilepsy.
    Lancet (London, England), 1990, Sep-15, Volume: 336, Issue:8716

    Topics: Child; Humans; Phenobarbital; Seizures, Febrile

1990
Management of febrile seizures: current concepts and recommendations for phenobarbital and the electroencephalogram.
    Clinical EEG (electroencephalography), 1991, Volume: 22, Issue:1

    Topics: Acute Disease; Child, Preschool; Drug Utilization; Electroencephalography; Family Practice; Humans;

1991
Phenobarbital for febrile seizures.
    The New England journal of medicine, 1990, Aug-16, Volume: 323, Issue:7

    Topics: Child; Humans; Intelligence; Phenobarbital; Seizures, Febrile

1990
Febrile convulsion--a clinical survey and a review of its current concept of management.
    The Journal of the Singapore Paediatric Society, 1989, Volume: 31, Issue:3-4

    Topics: Child; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Retrospective Studies; Seizure

1989
Epilepsy and mental retardation following febrile seizures in childhood.
    Acta paediatrica Scandinavica, 1989, Volume: 78, Issue:2

    Topics: Child; Child, Preschool; Epilepsy; Humans; Infant; Intellectual Disability; Phenobarbital; Recurrenc

1989
[Prognosis of complicated febrile convulsions in therapy with primidone, cathine-phenobarbital and calcium valproinate].
    Kinderarztliche Praxis, 1988, Volume: 56, Issue:10

    Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Male; Phenobarbital; Phe

1988
The value of investigations, the significance of perinatal and family histories and the prevalence of side effects to phenobarbitone in children with recurrent seizures.
    Singapore medical journal, 1986, Volume: 27, Issue:6

    Topics: Child Behavior; Epilepsy; Female; Humans; Infant, Newborn; Male; Phenobarbital; Pregnancy; Recurrenc

1986
Effects of phenobarbital on early intellectual and behavioral development: a concordant twin case study.
    Journal of clinical and experimental neuropsychology, 1987, Volume: 9, Issue:4

    Topics: Child Behavior; Diseases in Twins; Humans; Infant; Intelligence; Phenobarbital; Seizures, Febrile

1987
Management of febrile seizures in a developing country.
    The Journal of tropical medicine and hygiene, 1987, Volume: 90, Issue:4

    Topics: Child; Child, Preschool; Developing Countries; Humans; Infant; Medicine, Ayurvedic; Medicine, Tradit

1987
Carbamazepine in febrile seizures.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:1

    Topics: Carbamazepine; Humans; Infant; Phenobarbital; Seizures, Febrile

1985
Recurrence of febrile convulsions and phenobarbital treatment.
    Acta paediatrica Scandinavica, 1985, Volume: 74, Issue:2

    Topics: Child; Humans; Phenobarbital; Recurrence; Risk; Seizures, Febrile

1985
[Convulsive crises in childhood].
    Anales espanoles de pediatria, 1985, Volume: 23, Issue:8

    Topics: Clonazepam; Crying; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Mi

1985