phenobarbital has been researched along with Scleroderma, Systemic in 3 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
Excerpt | Relevance | Reference |
---|---|---|
"Features of both systemic lupus erythematosus and scleroderma developed in a young Chinese girl while on multiple anticonvulsant therapy." | 1.25 | Lupus-scleroderma syndrome induced by ethosuximide. ( Chan, HL; Teoh, PC, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Teoh, PC | 1 |
Chan, HL | 1 |
August, PJ | 1 |
Durepaire-Fischer, R | 1 |
Goudal, H | 1 |
Bolgert, M | 1 |
3 other studies available for phenobarbital and Scleroderma, Systemic
Article | Year |
---|---|
Lupus-scleroderma syndrome induced by ethosuximide.
Topics: Adolescent; Anemia; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Lupus Erythematosus, Syste | 1975 |
Primary biliary cirrhosis and scleroderma.
Topics: Cholestyramine Resin; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Phenobarbital; Sclerode | 1974 |
[Late cutaneous porphyria with sclerodermic syndrome revealed by taking estrogens, barbiturates and estro-progestational hormones].
Topics: Adult; Amenorrhea; Chemical and Drug Induced Liver Injury; Female; Humans; Lynestrenol; Mestranol; P | 1969 |