phenobarbital has been researched along with Respiratory Insufficiency in 13 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital-treated infants were over eight times more likely to experience IVH than were untreated infants." | 2.66 | Effect of phenobarbital on motor activity and intraventricular hemorrhage in preterm infants with respiratory disease weighing less than 1500 grams. ( Marshall, RE; Miller, RH; Moore, JA; Porter, FL, 1985) |
| "Phenobarbital is a safe alternative to diazepam in the treatment of DT." | 1.36 | Phenobarbital versus diazepam for delirium tremens--a retrospective study. ( Allerup, P; Anderson, JE; Fink-Jensen, A; Hjermø, I; Ulrichsen, J, 2010) |
| "22 patients with severe preeclampsia-eclampsia were treated in our Intensive Care Unit from 1972 to 1978." | 1.26 | [Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)]. ( Larsen, R; Radke, J; Turner, E, 1980) |
| "Recurrent acute respiratory failure in an epileptic subject is described." | 1.25 | Respiratory failure as a seizure phenomenon. A case report. ( Malatinský, J; Procházka, M; Sámel, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hjermø, I | 1 |
| Anderson, JE | 1 |
| Fink-Jensen, A | 1 |
| Allerup, P | 1 |
| Ulrichsen, J | 1 |
| HERBERG, D | 1 |
| GEISLER, L | 1 |
| SCHENCK, P | 1 |
| CORDA, M | 1 |
| EKLUND, G | 1 |
| Larsen, R | 1 |
| Turner, E | 1 |
| Radke, J | 1 |
| Melvin, GR | 1 |
| Aceto, T | 1 |
| Barlow, J | 1 |
| Munson, D | 1 |
| Wierda, D | 1 |
| Malatinský, J | 1 |
| Procházka, M | 1 |
| Sámel, M | 1 |
| Kattner, E | 1 |
| Menzies, DG | 1 |
| Busuttil, A | 1 |
| Prescott, LF | 1 |
| Herranz Fernández, JL | 1 |
| Porter, FL | 1 |
| Marshall, RE | 1 |
| Moore, JA | 1 |
| Miller, RH | 1 |
| Picaza, JA | 1 |
| Hunter, SE | 1 |
| Lee, L | 1 |
| Sheffer, AL | 1 |
| Dezoteux, H | 1 |
| Vinceneux, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464] | Phase 4 | 142 participants (Anticipated) | Interventional | 2020-07-06 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for phenobarbital and Respiratory Insufficiency
| Article | Year |
|---|---|
[Findings in newborn infants following drug abuse or drug weaning in the mother].
Topics: Abnormalities, Drug-Induced; Adult; Female; Fetal Growth Retardation; Heroin Dependence; Humans; Inf | 1991 |
1 trial available for phenobarbital and Respiratory Insufficiency
| Article | Year |
|---|---|
Effect of phenobarbital on motor activity and intraventricular hemorrhage in preterm infants with respiratory disease weighing less than 1500 grams.
Topics: Apgar Score; Cerebral Hemorrhage; Cerebral Ventricles; Humans; Infant, Low Birth Weight; Infant, New | 1985 |
11 other studies available for phenobarbital and Respiratory Insufficiency
| Article | Year |
|---|---|
Phenobarbital versus diazepam for delirium tremens--a retrospective study.
Topics: Alcohol Withdrawal Delirium; Diazepam; Female; Humans; Hypnotics and Sedatives; Male; Phenobarbital; | 2010 |
[ON THE INFLUENCE OF SOME FREQUENTLY USED SEDATIVES AND ANALGESICS ON THE HUMAN RESPIRATORY CENTER WITH SPECIAL REFERENCE TO PATIENTS WITH ALVEOLAR HYPOVENTILATION].
Topics: Analgesics; Apnea; Humans; Hypnotics and Sedatives; Hypoventilation; Medulla Oblongata; Meperidine; | 1963 |
EXTERNAL INTERCOSTAL AND PHRENIC ALPHA-MOTOR RESPONSES TO CHANGES IN RESPIRATORY LOAD.
Topics: Cats; Diaphragm; Intercostal Muscles; Muscle Spindles; Neurophysiology; Phenobarbital; Research; Res | 1965 |
[Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)].
Topics: Acute Kidney Injury; Adolescent; Adult; Brain Edema; Critical Care; Diazepam; Dihydralazine; Eclamps | 1980 |
Iatrogenic congenital goiter and hypothyroidism with respiratory distress in a newborn.
Topics: Asthma; Congenital Hypothyroidism; Ephedrine; Female; Goiter; Humans; Hypothyroidism; Infant, Newbor | 1978 |
Respiratory failure as a seizure phenomenon. A case report.
Topics: Brain Edema; Diazepam; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Respiratory Insufficiency | 1975 |
Fatal pulmonary aspiration of oral activated charcoal.
Topics: Charcoal; Death, Sudden; Humans; Male; Middle Aged; Phenobarbital; Pneumonia, Aspiration; Respirator | 1988 |
[Convulsive crises in childhood].
Topics: Clonazepam; Crying; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Mi | 1985 |
Seizures associated with the use of meglumine iothalamate 60 per cent in ventriculography.
Topics: Adult; Brain; Cerebral Ventriculography; Child; Curare; Diazepam; Electroencephalography; Female; Hu | 1972 |
Treatment of anaphylaxis.
Topics: Anaphylaxis; Desensitization, Immunologic; Diphenhydramine; Drug Hypersensitivity; Ephedrine; Epinep | 1973 |
[The lung and massive intentional poisoning by organo-phosphoric substances].
Topics: Adolescent; Adult; DDT; Female; Humans; Insecticides; Lung; Lung Diseases; Male; Parasympatholytics; | 1970 |