phenobarbital has been researched along with Respiratory Distress Syndrome, Newborn in 13 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Respiratory Distress Syndrome, Newborn: A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An 11-month-old boy with multiple surface anomalies and respiratory distress due to upper airway narrowing developed generalized tonic seizures coinciding with apnea." | 7.73 | [High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome]. ( Hayashi, T; Horio, K; Kubota, M; Mimaki, M; Tomita, S, 2006) |
| "An 11-month-old boy with multiple surface anomalies and respiratory distress due to upper airway narrowing developed generalized tonic seizures coinciding with apnea." | 3.73 | [High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome]. ( Hayashi, T; Horio, K; Kubota, M; Mimaki, M; Tomita, S, 2006) |
| " Therefore phenobarbitone does not have seem to have any significant effect on cerebral haemodynamics up to a dosage of 20 mg/kg, so that there is no apparent effect on the risk of cerebral haemorrhage." | 2.66 | [Doppler flow velocities in cerebral arteries in relation to intravenous phenobarbital in premature infants weighing between 500 and 1,500 g]. ( Jorch, G; Michel, E; Rabe, H; Rickers, E; Stöhr, G; Süllwald, A, 1988) |
| "Infant delirium is an under-recognized clinical entity in neonatal intensive care, and earlier identification and treatment could minimize morbidities associated with this condition." | 1.46 | A case of infant delirium in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB, 2017) |
| "Phenobarbital levels were higher in symptomatic infants than asymptomatic infants, although the difference was not statistically significant." | 1.37 | Infants born to mothers under phenobarbital treatment: correlation between serum levels and clinical features of neonates. ( Antichi, E; Cardiello, V; Carducci, C; Catenazzi, P; D'Antuono, A; Piras, A; Pozzoli, G; Romagnoli, C; Scorrano, A; Zuppa, AA, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, LE | 1 |
| Hutchison, LB | 1 |
| Hornik, CD | 1 |
| Smith, PB | 1 |
| Cotten, CM | 1 |
| Bidegain, M | 1 |
| Zuppa, AA | 1 |
| Carducci, C | 1 |
| Scorrano, A | 1 |
| Antichi, E | 1 |
| Catenazzi, P | 1 |
| Piras, A | 1 |
| Pozzoli, G | 1 |
| Cardiello, V | 1 |
| D'Antuono, A | 1 |
| Romagnoli, C | 1 |
| Hayashi, T | 1 |
| Kubota, M | 1 |
| Mimaki, M | 1 |
| Tomita, S | 1 |
| Horio, K | 1 |
| Wimberley, PD | 1 |
| Lou, HC | 1 |
| Pedersen, H | 1 |
| Hejl, M | 1 |
| Lassen, NA | 1 |
| Friis-Hansen, B | 4 |
| Glade, G | 1 |
| Saccar, CL | 1 |
| Pereira, GR | 1 |
| Leviton, A | 1 |
| Kuban, KC | 1 |
| Pagano, M | 1 |
| Allred, EN | 1 |
| Van Marter, L | 1 |
| Koh, KS | 1 |
| Andersen, G | 1 |
| Faerø, O | 2 |
| Osler, M | 2 |
| Trolle, D | 2 |
| Vargas, GC | 1 |
| Pildes, RS | 1 |
| Vidyasagar, D | 1 |
| Keith, LG | 1 |
| Jorch, G | 1 |
| Rickers, E | 1 |
| Rabe, H | 1 |
| Stöhr, G | 1 |
| Süllwald, A | 1 |
| Michel, E | 1 |
| Morales, WJ | 1 |
| Koerten, J | 1 |
1 review available for phenobarbital and Respiratory Distress Syndrome, Newborn
| Article | Year |
|---|---|
Premature labour.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Albuterol; Amnion; Anti-Bacterial Agents; Bacteri | 1976 |
3 trials available for phenobarbital and Respiratory Distress Syndrome, Newborn
| Article | Year |
|---|---|
Antenatal corticosteroids appear to reduce the risk of postnatal germinal matrix hemorrhage in intubated low birth weight newborns.
Topics: Cerebral Hemorrhage; Glucocorticoids; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Pre | 1993 |
[Doppler flow velocities in cerebral arteries in relation to intravenous phenobarbital in premature infants weighing between 500 and 1,500 g].
Topics: Birth Weight; Blood Flow Velocity; Cerebrovascular Circulation; Echoencephalography; Humans; Infant, | 1988 |
Prevention of intraventricular hemorrhage in very low birth weight infants by maternally administered phenobarbital.
Topics: Administration, Oral; Cerebral Hemorrhage; Female; Fetal Monitoring; Fetal Organ Maturity; Humans; I | 1986 |
9 other studies available for phenobarbital and Respiratory Distress Syndrome, Newborn
| Article | Year |
|---|---|
A case of infant delirium in the neonatal intensive care unit.
Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acid | 2017 |
Infants born to mothers under phenobarbital treatment: correlation between serum levels and clinical features of neonates.
Topics: Adult; Anticonvulsants; Cohort Studies; Epilepsy; Female; Hospitals, University; Humans; Infant, New | 2011 |
[High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome].
Topics: Abnormalities, Multiple; Anticonvulsants; Apnea; Cough; Humans; Infant, Newborn; Male; Phenobarbital | 2006 |
Hypertensive peaks in the pathogenesis of intraventricular hemorrhage in the newborn. Abolition by phenobarbitone sedation.
Topics: Blood Pressure; Cerebral Hemorrhage; Female; Humans; Hypertension; Infant, Newborn; Infant, Prematur | 1982 |
Cimetidine in pregnancy: apparent transient liver impairment in the newborn.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cimetidine; Fema | 1980 |
Hypercholesterolemia in the newborn: occurrence after anterpartum treatment with betamethasone-phenobarbital-ritodrine for the prevention of the respiratory distress syndrome.
Topics: Betamethasone; Cholesterol; Female; Humans; Hypercholesterolemia; Infant, Newborn; Infant, Newborn, | 1978 |
Antepartum glucocorticoid therapy combined with phenobarbitone and ritodrine for prevention of respiratory distress syndrome (RDS) in pre-term infants.
Topics: Betamethasone; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Infant Mortality; Infant, | 1979 |
Prevention of the respiratory distress syndrome (RDS) by antepartum glucocorticoid (betamethasone) therapy combined with phenobarbitone and ritodrine.
Topics: Betamethasone; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Obstetric Labor, Prematur | 1978 |
Effect of maternal heroin addiction on 67 liveborn neonates. Withdrawal symptoms, small body size, and small head circumference were frequent findings.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Birth Weight; Blood Glucose; Cephalomet | 1975 |