phenobarbital has been researched along with Reflex Sympathetic Dystrophy in 23 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Reflex Sympathetic Dystrophy: A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33)
| Excerpt | Relevance | Reference |
|---|---|---|
| " I reviewed the charts of 99 patients treated with PB to assess the incidence, clinical characteristics, investigations, dosage and plasma concentration of PB, and risk factors in the development of CRPS-I." | 1.33 | [Complex regional pain syndrome type I induced by phenobarbital]. ( Tanabe, Y, 2006) |
| " In these patients SHS developed during the first 7 months of therapy and regressed after PB discontinuation or, in 2 cases, after dosage reduction." | 1.31 | Shoulder-hand syndrome in neurosurgical patients treated with barbiturates. A long term evaluation. ( Bello, L; Ceccarelli, G; Cesana, BM; De Santis, A; Spagnoli, D; Villani, RM, 2000) |
| "Amongst 149 cases of reflex sympathetic dystrophy syndrome (RSDS), 25 (16." | 1.27 | Reflex sympathetic dystrophy syndrome and barbiturates. A study of 25 cases treated with barbiturates compared with 124 cases treated without barbiturates. ( Gerster, JC; Horton, P, 1984) |
| "A case of phenobarbital-induced algodystrophy is reported." | 1.27 | [Algodystrophy in the chronic stage following treatment with phenobarbital]. ( Albert, J; Waldburger, M, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (60.87) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 4 (17.39) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanabe, Y | 1 |
| Hamza, SI | 1 |
| Hassen, Z | 1 |
| Loueslati, MH | 1 |
| Toghourti, MN | 1 |
| Belkahia, C | 1 |
| Hamza, M | 1 |
| Zarranz, JJ | 1 |
| Baroja, A | 1 |
| de la Hoz, C | 1 |
| Inclán, G | 1 |
| Forcadas, I | 1 |
| Horton, P | 1 |
| Gerster, JC | 1 |
| Albert, J | 1 |
| Waldburger, M | 1 |
| Lucantoni, C | 1 |
| Grottoli, S | 1 |
| Bianchini, LM | 1 |
| Gaetti, R | 1 |
| Gabriel Botella, F | 1 |
| Labios Gómez, M | 1 |
| Galindo Puerto, MJ | 1 |
| Chapa Villalba, MA | 1 |
| Gómez Aldaravi Gutiérrez, R | 1 |
| Olazarán, J | 1 |
| Farcha, I | 1 |
| Tamayo, JA | 1 |
| León, A | 1 |
| Fernández, O | 1 |
| Rovetta, G | 2 |
| Baratto, L | 2 |
| Monteforte, P | 2 |
| De Santis, A | 1 |
| Ceccarelli, G | 1 |
| Cesana, BM | 1 |
| Bello, L | 1 |
| Spagnoli, D | 1 |
| Villani, RM | 1 |
| Farinelli, G | 1 |
| Taylor, LP | 1 |
| Posner, JB | 1 |
| Reddy, MP | 1 |
| Cuchacovich, M | 1 |
| Kappes, J | 1 |
| Sánchez Navarro, JJ | 1 |
| del Pino Montes, J | 1 |
| Cordero Sánchez, M | 1 |
| Fermoso García, J | 1 |
| Blanquart, F | 1 |
| Houdent, G | 1 |
| Deshayes, P | 1 |
| Walther, G | 1 |
| van der Korst, JK | 1 |
| Colenbrander, H | 1 |
| Cats, A | 1 |
| Arlet, J | 1 |
| Rascol, A | 1 |
| Mole, J | 1 |
| Roger, JM | 1 |
| Lequesne, M | 2 |
1 review available for phenobarbital and Reflex Sympathetic Dystrophy
| Article | Year |
|---|---|
[Reflex sympathetic dystrophy of the upper limb secondary to barbiturate treatment. A report of 3 cases and a review of the literature].
Topics: Aged; Arm; Barbiturates; Female; Humans; Male; Middle Aged; Phenobarbital; Reflex Sympathetic Dystro | 1994 |
1 trial available for phenobarbital and Reflex Sympathetic Dystrophy
| Article | Year |
|---|---|
Low dose gabapentin for shoulder-hand syndrome induced by phenobarbital: a three-month study.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Dr | 1999 |
21 other studies available for phenobarbital and Reflex Sympathetic Dystrophy
| Article | Year |
|---|---|
[Complex regional pain syndrome type I induced by phenobarbital].
Topics: Aged; Anticonvulsants; Female; Humans; Male; Middle Aged; Phenobarbital; Quality of Life; Reflex Sym | 2006 |
[Recurrent bilateral shoulder hand syndrome induced by phenobarbital].
Topics: Aged; Anticonvulsants; Female; Humans; Phenobarbital; Recurrence; Reflex Sympathetic Dystrophy | 2003 |
[Shoulder-hand syndrome and scapulo-humeral periarthritis in adult epileptics treated with phenobarbital].
Topics: Female; Humans; Male; Periarthritis; Phenobarbital; Reflex Sympathetic Dystrophy; Shoulder Joint | 1982 |
Reflex sympathetic dystrophy syndrome and barbiturates. A study of 25 cases treated with barbiturates compared with 124 cases treated without barbiturates.
Topics: Adult; Aged; Barbiturates; Female; Humans; Male; Middle Aged; Nervous System Diseases; Phenobarbital | 1984 |
[Algodystrophy in the chronic stage following treatment with phenobarbital].
Topics: Chronic Disease; Diagnosis, Differential; Humans; Male; Middle Aged; Phenobarbital; Reflex Sympathet | 1983 |
[Reflex sympathetic dystrophy syndrome associated with phenobarbital].
Topics: Aged; Anticonvulsants; Bone Resorption; Brain Injuries; Diphosphonates; Epilepsy, Generalized; Human | 1996 |
[Reflex sympathetic dystrophy due to phenobarbital: a frequent and treatable condition].
Topics: Aged; Anticonvulsants; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Reflex Sympathetic Dystro | 1997 |
[Bilateral sympathetic reflex dystrophy related to phenobarbital].
Topics: Anticonvulsants; Epilepsy; Female; Humans; Middle Aged; Phenobarbital; Reflex Sympathetic Dystrophy | 1998 |
Shoulder-hand syndrome in neurosurgical patients treated with barbiturates. A long term evaluation.
Topics: Adult; Barbiturates; Craniocerebral Trauma; Female; Follow-Up Studies; Humans; Intracranial Aneurysm | 2000 |
Three-month follow-up of shoulder-hand syndrome induced by phenobarbital and treated with gabapentin.
Topics: Acetaminophen; Acetates; Amines; Analgesics; Anticonvulsants; Arthralgia; Cyclohexanecarboxylic Acid | 2001 |
Phenobarbital rheumatism in patients with brain tumor.
Topics: Brain Neoplasms; Humans; Phenobarbital; Reflex Sympathetic Dystrophy | 1989 |
Bilateral shoulder-hand syndrome associated with phenobarbital administration. A case report.
Topics: Female; Humans; Middle Aged; Phenobarbital; Physical Therapy Modalities; Reflex Sympathetic Dystroph | 1985 |
[Algoneurodystrophy caused by phenobarbital].
Topics: Aged; Epilepsy, Absence; Humans; Male; Phenobarbital; Reflex Sympathetic Dystrophy | 1987 |
[Reflex sympathetic dystrophy syndrome caused by phenobarbitol].
Topics: Aged; Female; Humans; Male; Middle Aged; Phenobarbital; Radionuclide Imaging; Reflex Sympathetic Dys | 1987 |
[Iatrogenic algodystrophy caused by phenobarbitone].
Topics: Anxiety Disorders; Diabetes Complications; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbita | 1974 |
[On the technic of block of the stellate ganglion].
Topics: Anesthesia, Local; Anesthetics, Local; Atropine; Brachial Plexus Neuritis; Drug Synergism; Humans; N | 1966 |
Phenobarbital and the shoulder-hand syndrome.
Topics: Adult; Aged; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Reflex Sympathetic Dystroph | 1966 |
Phenobarbitone and the shoulder-hand syndrome.
Topics: Humans; Phenobarbital; Reflex Sympathetic Dystrophy | 1967 |
[Cases of "Gardenal rheumatism"].
Topics: Adult; Aged; Diagnosis, Differential; Female; Humans; Joint Diseases; Male; Middle Aged; Phenobarbit | 1967 |
[Algodystrophy of chemotherapeutic origin. Pseudorheumatism due to isoniazid, ethionamide, phenobarbital and radioactive iodine].
Topics: Adult; Aged; Ethionamide; Female; Humans; Iodine Isotopes; Isoniazid; Male; Middle Aged; Phenobarbit | 1967 |
[Etiology and pathogenesis of algodystrophies].
Topics: Antitubercular Agents; Cardiovascular Diseases; Extremities; Humans; Infections; Lung Diseases; Nerv | 1968 |