Page last updated: 2024-11-02

phenobarbital and Recrudescence

phenobarbital has been researched along with Recrudescence in 121 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
"This study investigated treatment patterns at discharge in infants with neonatal seizures and evaluated the impact of outpatient phenobarbital prophylaxis on the frequency of seizure recurrence and the long-term neurodevelopmental outcome at 1 to 11 years."9.12Seizure recurrence and developmental disabilities after neonatal seizures: outcomes are unrelated to use of phenobarbital prophylaxis. ( Guillet, R; Kwon, J, 2007)
"To determine the efficacy of pyridoxine in treating seizures, 90 infants and children with recurrent convulsions primarily due to acute infectious diseases were enrolled in the present study."9.08Randomized, controlled trial of high-dose intravenous pyridoxine in the treatment of recurrent seizures in children. ( Bai, AN; Cao, YM; Chui, W; Gao, DY; Ge, ZL; Jiao, FY; Li, HR; Lieu, NS; Liu, SB; Liu, ZY; Takuma, Y; Wu, S; Zhang, XK, 1997)
"To review the best evidence comparing phenobarbitone and phenytoin when used as monotherapy in participants with partial onset seizures or generalised tonic-clonic seizures with or without other generalised seizure types."8.89Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures. ( Marson, AG; Nolan, SJ; Pulman, J; Tudur Smith, C, 2013)
"To analyse the impact of both epilepsy and pharmacological modulation of P-glycoprotein on brain uptake and kinetics of positron emission tomography (PET) radiotracers [(11)C]quinidine and [(11)C]laniquidar."7.79[11C]quinidine and [11C]laniquidar PET imaging in a chronic rodent epilepsy model: impact of epilepsy and drug-responsiveness. ( de Lange, EC; Eriksson, J; Koepp, M; Labots, M; Lammertsma, AA; Potschka, H; Rongen, M; Russmann, V; Schuit, R; Seeger, N; Syvänen, S; van Kooij, R; Verbeek, J; Voskuyl, RA; Windhorst, AD; Zellinger, C, 2013)
"The failure of the maximum tolerated dosage to improve seizure control in dogs with phenobarbital-resistant epilepsy argues against the suitability of verapamil add-on treatment to overcome pharmacoresistance."7.77Add-on treatment with verapamil in pharmacoresistant canine epilepsy. ( Jambroszyk, M; Potschka, H; Tipold, A, 2011)
"All of them were generalized convulsive status epilepticus (GCSE)."5.34Very high dose phenobarbital for refractory status epilepticus. ( Arunpongpaisal, S; Auevitchayapat, N; Chaiyakum, A; Jitpimolmard, S; Mayurasakorn, N; Phunikhom, K; Phuttharak, W; Saengsuwan, J; Suko, P; Tiamkao, S; Vannaprasaht, S, 2007)
"Mexiletine has a little first pass hepatic metabolism and a large volume of distribution along with a high lipid solubility, and prolonged central nervous system toxicity may be expected."5.29Mexiletine overdose producing status epilepticus without cardiovascular abnormalities. ( Hoffman, RS; Nelson, LS, 1994)
"This study investigated treatment patterns at discharge in infants with neonatal seizures and evaluated the impact of outpatient phenobarbital prophylaxis on the frequency of seizure recurrence and the long-term neurodevelopmental outcome at 1 to 11 years."5.12Seizure recurrence and developmental disabilities after neonatal seizures: outcomes are unrelated to use of phenobarbital prophylaxis. ( Guillet, R; Kwon, J, 2007)
"Phenobarbital is commonly used to treat status epilepticus in resource-poor countries."5.10Pharmacokinetics and clinical effect of phenobarbital in children with severe falciparum malaria and convulsions. ( Kokwaro, GO; Muchohi, SN; Newton, CR; Ogutu, BR; Otieno, GO, 2003)
"To determine the efficacy of pyridoxine in treating seizures, 90 infants and children with recurrent convulsions primarily due to acute infectious diseases were enrolled in the present study."5.08Randomized, controlled trial of high-dose intravenous pyridoxine in the treatment of recurrent seizures in children. ( Bai, AN; Cao, YM; Chui, W; Gao, DY; Ge, ZL; Jiao, FY; Li, HR; Lieu, NS; Liu, SB; Liu, ZY; Takuma, Y; Wu, S; Zhang, XK, 1997)
"To review the time to treatment failure, remission and first seizure with carbamazepine compared with phenobarbitone when used as monotherapy in people with focal onset seizures (simple or complex focal and secondarily generalised), or generalised onset tonic-clonic seizures (with or without other generalised seizure types)."4.98Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review. ( Marson, AG; Nevitt, SJ; Tudur Smith, C, 2018)
"To review the best evidence comparing phenobarbitone and phenytoin when used as monotherapy in participants with partial onset seizures or generalised tonic-clonic seizures with or without other generalised seizure types."4.89Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures. ( Marson, AG; Nolan, SJ; Pulman, J; Tudur Smith, C, 2013)
" Intermittent diazepam prophylaxis at times of fever may or may not reduce the recurrence rate significantly, but there is no data to suggest that it improves the long-term outcome, as compared with short-term seizure control, in terms of IQ, cognition, academic progress, motor control, and subsequent epilepsy."4.81[Febrile convulsions, Treatment and prognosis]. ( Knudsen, FU, 2001)
"To analyse the impact of both epilepsy and pharmacological modulation of P-glycoprotein on brain uptake and kinetics of positron emission tomography (PET) radiotracers [(11)C]quinidine and [(11)C]laniquidar."3.79[11C]quinidine and [11C]laniquidar PET imaging in a chronic rodent epilepsy model: impact of epilepsy and drug-responsiveness. ( de Lange, EC; Eriksson, J; Koepp, M; Labots, M; Lammertsma, AA; Potschka, H; Rongen, M; Russmann, V; Schuit, R; Seeger, N; Syvänen, S; van Kooij, R; Verbeek, J; Voskuyl, RA; Windhorst, AD; Zellinger, C, 2013)
"The failure of the maximum tolerated dosage to improve seizure control in dogs with phenobarbital-resistant epilepsy argues against the suitability of verapamil add-on treatment to overcome pharmacoresistance."3.77Add-on treatment with verapamil in pharmacoresistant canine epilepsy. ( Jambroszyk, M; Potschka, H; Tipold, A, 2011)
"Rats in experiment 1 received 1% creatine or cyclocreatine chow from age (P) 21-65 days, underwent kainate induced status epilepticus on P35 and were compared, as adults, to kainate alone rats and to normal controls."3.72Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats. ( Abu Rialy, S; Farhat, F; Francis, E; Geha, G; Kurdit, RM; Lteif, L; Maraashli, W; Mikati, MA; Rahmeh, AA, 2004)
"The effect of pretreatment with either tetanus toxin (in ventral hippocampus) or kainic acid (into dorsal hippocampus, with or without suppression of seizures by phenobarbital) on the subsequent development of epilepsy in rats injected with tetanus toxin (into ventral hippocampus) has been studied."3.71Do fits really beget fits? The effect of previous epileptic activity on the subsequent induction of the tetanus toxin model of limbic epilepsy in the rat. ( Mellanby, J; Milward, AJ, 2001)
" Hence we feel that daily low-dose phenobarbital therapy is a safe and effective therapy in preventing episodes of cyclic vomiting in children."3.69Use of barbiturates in the treatment of cyclic vomiting during childhood. ( Brady, L; Gokhale, R; Huttenlocher, PR; Kirschner, BS, 1997)
"Pentobarbital is standard treatment for refractory status epilepticus (SE) and is almost uniformly effective, but the morbidity of treatment and the mortality of refractory SE are high."3.69Relapse and survival after barbiturate anesthetic treatment of refractory status epilepticus. ( Drislane, FW; Krishnamurthy, KB, 1996)
" The administration of daily phenobarbital did not reduce the frequency of epilepsy, in spite of a significant reduction in the incidence of recurrent febrile seizures."3.67Epilepsy and mental retardation following febrile seizures in childhood. ( Forsythe, A; Wolf, SM, 1989)
"Phenobarbital and LZ were similarly effective in the treatment of mild/moderate alcohol withdrawal in the ED and at 48 hours."2.76A prospective, randomized, trial of phenobarbital versus benzodiazepines for acute alcohol withdrawal. ( Barnes, RL; Dery, RA; Hendey, GW; Mentler, P; Snowden, B, 2011)
" Four patients experienced relapse with a decreased dosage of valproate."2.74Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate. ( Amakata, K; Fujii, Y; Hikita, T; Kaga, F; Kaneko, S; Kodama, H; Nakamoto, N; Ogita, K; Yanagawa, Y, 2009)
"The most important factor determining seizure recurrence was continued therapy, which was the case for barbiturates, phenytoin and valproate."2.69Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study. ( Chadwick, D, 1999)
"The proportion of children with recurrence did not differ among the 3 groups."2.68Comparison of phenobarbitone, phenytoin with sodium valproate: randomized, double-blind study. ( Banu, K; Ratnam, RS; Thilothammal, N, 1996)
"Children with simple febrile convulsions were randomly allocated to receive either phenobarbitone or placebo."2.67Role of phenobarbitone in preventing recurrence of febrile convulsions. ( Ahamed, S; Banu, K; Kamala, KG; Krishnamurthy, PV; Thilothammal, N, 1993)
"Phenytoin was an ineffective prophylactic agent."2.65Placebo-controlled study of phenobarbitone and phenytoin in the prophylaxis of febrile convulsions. ( Bacon, CJ; Hierons, AM; Mucklow, JC; Rawlins, MD; Webb, JK; Weightman, D, 1981)
" They were subsequently followed up as outpatients, and Phenobarbital and sodium valproate levels were measured regularly to ascertain compliance with the treatment and to adjust the dosage accordingly."2.65Prevention of recurrent febrile convulsions--a randomized therapeutic assay: sodium valproate, phenobarbital and placebo. ( Gilly, R; Mamelle, JC; Mamelle, N; Plasse, JC; Revol, M, 1984)
" The dosage was phenobarbitone 3-6 mg/kg per day; sodium valproate 30-60 mg/kg per day."2.65Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions. Comparison by a double-blind trial. ( Bower, B; Ngwane, E, 1980)
"New convulsions were of similar duration and severity in both groups."2.64Prophylactic diazepam or phenobarbitone in febrile convulsions: a prospective, controlled study. ( Knudsen, FU; Vestermark, S, 1978)
"13% had seizures which were either lateralized or longer than ten minutes."2.64The value of phenobarbital in the child who has had a single febrile seizure: a controlled prospective study. ( Carr, A; Dale, EP; Davidson, S; Davis, DC; Forsythe, A; Goldenberg, ED; Hanson, R; Lulejian, GA; Nelson, MA; Treitman, P; Weinstein, A; Wolf, SM, 1977)
"The recurrence rate of febrile convulsions is assessed in 108 children who had had either prolonged or repeated initial fits or had both a positive family history and persisting neurological disorder."2.64Continuous phrophylcatic anticonvulsants in selected childrens with febrile convulsions. ( Wallace, SJ, 1975)
"Children with simple febrile seizures only have a slightly increased risk of epilepsy."2.42[Febrile seizures--an update]. ( Püst, B, 2004)
"The risk of recurrences was significantly lower in children receiving continuous phenobarbital therapy than placebo (odds ratio 0."2.40A meta-analytic review of the preventive treatment of recurrences of febrile seizures. ( Rantala, H; Tarkka, R; Uhari, M, 1997)
"Febrile seizures are a common problem."2.37Febrile seizures: emergency department diagnosis and treatment. ( Ater, SB; Bettis, DB, 1985)
"The natural history of febrile seizures, the recurrence rate, and frequency of later epilepsy or intellectual handicap is presented, and controversies in evaluation and treatment are discussed."2.36The natural history of febrile seizures. ( Hirtz, DG; Nelson, KB, 1983)
"He developed electrographic seizures for the first time during the warming phase, which continued in the hours after rewarming."1.38Recooling for rebound seizures after rewarming in neonatal encephalopathy. ( Kendall, GS; Mathieson, S; Meek, J; Rennie, JM, 2012)
"Five days later, febrile convulsions were induced by hyperthermal bath (45 Celcius degree)."1.36[Prophylactic efficacy of levetiracetam, valproate or phenobarbital on febrile convulsions in rats]. ( Cheng, M; Huang, Z; Li, SX, 2010)
"Before treatment with PB, average seizure frequency in PB nonresponders was significantly higher than seizure frequency in responders, which, however, was due to six nonresponders that exhibited > 3 seizures per day."1.36High seizure frequency prior to antiepileptic treatment is a predictor of pharmacoresistant epilepsy in a rat model of temporal lobe epilepsy. ( Brandt, C; Löscher, W, 2010)
"A cat with a history of seizures and clinical suspicion of forebrain disorder underwent a brain magnetic resonance imaging."1.35Toxoplasma gondii brain granuloma in a cat: diagnosis using cytology from an intraoperative sample and sequential magnetic resonance imaging. ( Baroni, M; De Lorenzi, D; Falzone, C; Mandara, MT, 2008)
"All of them were generalized convulsive status epilepticus (GCSE)."1.34Very high dose phenobarbital for refractory status epilepticus. ( Arunpongpaisal, S; Auevitchayapat, N; Chaiyakum, A; Jitpimolmard, S; Mayurasakorn, N; Phunikhom, K; Phuttharak, W; Saengsuwan, J; Suko, P; Tiamkao, S; Vannaprasaht, S, 2007)
"Simple febrile seizures that occur in children ages 6 months to 5 years are common events with few adverse outcomes."1.30Technical report: treatment of the child with simple febrile seizures. ( Baumann, RJ, 1999)
"The first-line treatment for brain abscesses is still a much-debated argument."1.29Stereotactic aspiration and drainage of brain abscesses. Experience with 9 cases. ( Melatini, A; Sidoti, C; Skrap, M; Vassallo, A, 1996)
"Seizure recurrence was present in only three cases (8."1.29Low risk of seizure recurrence after early withdrawal of antiepileptic treatment in the neonatal period. ( Blennow, G; Hellström-Westas, L; Lindroth, M; Rosén, I; Svenningsen, NW, 1995)
"Mexiletine has a little first pass hepatic metabolism and a large volume of distribution along with a high lipid solubility, and prolonged central nervous system toxicity may be expected."1.29Mexiletine overdose producing status epilepticus without cardiovascular abnormalities. ( Hoffman, RS; Nelson, LS, 1994)
" Rats receiving phenobarbital had therapeutic concentrations during most of the 24-hour dosing period, but also experienced supratherapeutic peak concentrations."1.29Phenobarbital modifies seizure-related brain injury in the developing brain. ( Chronopoulos, A; Gatt, A; Holmes, GL; Hyde, P; Liu, Z; Mikati, MA; Stafstrom, CE; Thurber, S; Werner, S, 1994)
"Benign Familial Neonatal Seizures (BFNS) occur in normal newborns without perinatal neurological damage or metabolic abnormalities in the setting of a positive family history for neonatal seizures."1.28Benign Familial Neonatal Seizures. ( Dworsky, ME; Raispis, T, 1992)
"We report a patient with a seizure disorder on anticonvulsant therapy, who developed systemic reactive histiocytosis."1.28Reactive lymphohistiocytosis with recurrence in the optic chiasm. ( Galetta, SL; Hicks, DG; Oberholtzer, JC; Plock, G; Raps, EC; Stadtmauer, EA, 1991)
"There was a greater risk of recurrence among girls."1.28[Factors influencing the effectiveness of preventive treatment of febrile convulsions]. ( Armijo Simón, JA; Arteaga Manjón-Cabeza, R; Herranz Fernández, JL, 1989)
"Benign recurrent intrahepatic cholestasis is characterized by attacks of cholestasis."1.28Benign recurrent intrahepatic cholestasis. A report of 26 cases. ( Benhamou, JP; Brenard, R; Geubel, AP, 1989)
"Percentage of recurrences in phenobarbital treated cases (4 +/- 0,6 mg/Kg/d) was 18,67%, versus 55,89% in untreated children (p less than 0."1.27[Efficacy and failure of phenobarbital in the prevention of febrile convulsions. Importance of familial antecedents]. ( Blanco, A; Cilleruelo, ML; Palencia, R; Tresierra, F, 1983)
"Spontaneous myoclonus in alcohol withdrawal is likely to represent diffuse cerebral hyperirritability during the withdrawal state."1.27Recurrent spontaneous myoclonus in alcohol withdrawal. ( Drake, ME, 1983)
"Diazepam was found to be as effective as oral phenobarbital in the prevention of new febrile seizures."1.27[Continuous oral phenobarbital or intermittent rectal diazepam for the prevention of febrile convulsions]. ( Campos-Castelló, J; Careaga Maldonado, J; Oliete García, F, 1984)
"In the analysis of 128 patients with febrile convulsions, we identified hazards not encountered in the western world, which could alter the ultimate management of the child."1.27Management of febrile seizures in a developing country. ( Canagarayar, UT; Soysa, P, 1987)
"Of 196 children with febrile convulsions, 6."1.26Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions. ( Minagawa, K; Miura, H, 1981)
" Thus in adequate dosage both phenobarbitone and valproic acid were significantly better than no treatment in preventing febrile convulsions (p less than 0."1.26Successful prophylaxis against febrile convulsions with valproic acid or phenobarbitone. ( Smith, JA; Wallace, SJ, 1980)
"In the next three months, two recurrences of this syndrome were verified and successfully treated in a similar manner."1.25Recurrent hyperosmolar nonketotic episodes in a young diabetic. ( Ginsberg-Fellner, F; Primack, WA, 1975)

Research

Studies (121)

TimeframeStudies, this research(%)All Research%
pre-199074 (61.16)18.7374
1990's18 (14.88)18.2507
2000's17 (14.05)29.6817
2010's9 (7.44)24.3611
2020's3 (2.48)2.80

Authors

AuthorsStudies
Narod, SA1
Giannakeas, V1
Sopik, V1
Polavarapu, A1
Moshé, SL1
Renda, R1
Yüksel, D1
Gürer, YKY1
Nevitt, SJ1
Marson, AG2
Tudur Smith, C2
Nolan, SJ1
Pulman, J1
Syvänen, S1
Russmann, V1
Verbeek, J1
Eriksson, J1
Labots, M1
Zellinger, C1
Seeger, N1
Schuit, R1
Rongen, M1
van Kooij, R1
Windhorst, AD1
Lammertsma, AA1
de Lange, EC1
Voskuyl, RA1
Koepp, M1
Potschka, H2
Sachdeva, S1
Bhansali, P1
Fletcher, C1
Jones, A1
Miller, H1
Mittal, V1
Hikita, T1
Kodama, H1
Nakamoto, N1
Kaga, F1
Amakata, K1
Ogita, K1
Kaneko, S1
Fujii, Y1
Yanagawa, Y1
Löscher, W1
Brandt, C1
Striano, P1
Zara, F1
Minetti, C1
Striano, S1
Yadav, P1
Kumar, A1
Saili, A1
Datta, V1
Cheng, M1
Huang, Z1
Li, SX1
Hendey, GW1
Dery, RA1
Barnes, RL1
Snowden, B1
Mentler, P1
Jambroszyk, M1
Tipold, A1
Kendall, GS1
Mathieson, S1
Meek, J1
Rennie, JM1
Kokwaro, GO1
Ogutu, BR1
Muchohi, SN1
Otieno, GO1
Newton, CR1
HAMFELT, A1
KILLANDER, A1
MALERS, E1
DEVERDIER, CH1
Verrotti, A1
Latini, G1
Giannuzzi, R1
Cutarella, R1
Trotta, D1
Morgese, G1
Chiarelli, F1
Püst, B1
Mikati, MA2
Kurdit, RM1
Rahmeh, AA1
Farhat, F1
Abu Rialy, S1
Lteif, L1
Francis, E1
Geha, G1
Maraashli, W1
O'brien, CP1
Guillet, R1
Kwon, J1
Hamza, SI1
Hassen, Z1
Loueslati, MH1
Toghourti, MN1
Belkahia, C1
Hamza, M1
Falzone, C1
Baroni, M1
De Lorenzi, D1
Mandara, MT1
Kenny, JM1
Chipolombwe, MJ1
Molyneux, E1
Tiamkao, S2
Mayurasakorn, N1
Suko, P1
Jitpimolmard, S1
Arunpongpaisal, S1
Phuttharak, W1
Auevitchayapat, N1
Vannaprasaht, S1
Phunikhom, K1
Chaiyakum, A1
Saengsuwan, J1
Bacon, CJ1
Hierons, AM1
Mucklow, JC1
Webb, JK1
Rawlins, MD1
Weightman, D1
Stephenson, JB1
Hirtz, DG2
Nelson, KB2
Antony, JH1
Hawke, SH1
Escorihuela, R1
Sandiumenge, J1
Procopis, PG1
Mamelle, N2
Mamelle, JC2
Plasse, JC2
Revol, M2
Gilly, R2
Oliete García, F1
Campos-Castelló, J1
Careaga Maldonado, J1
Palencia, R1
Cilleruelo, ML1
Tresierra, F1
Blanco, A1
Wallace, SJ6
Haddock, ST1
Smith, JA2
Ngwane, E1
Bower, B1
Giles, HM1
Addy, DP1
Minagawa, K1
Miura, H1
Deering, WM1
Drake, ME1
Holliday, TA1
DeSilva, RA1
Graboys, TB1
Podrid, PJ1
Lown, B1
Gordon, N1
Camfield, PR1
Camfield, CS1
Tibbles, JA1
Pilgaard, S1
Hansen, FJ1
Paerregaard, P1
Wolf, SM5
Forsythe, A4
Stunden, AA1
Friedman, R1
Diamond, H1
Dockter, G1
Müller, J1
Hellström-Westas, L1
Blennow, G1
Lindroth, M1
Rosén, I1
Svenningsen, NW1
Nelson, LS1
Hoffman, RS1
Holmes, GL1
Chronopoulos, A1
Hyde, P1
Thurber, S1
Gatt, A1
Liu, Z1
Werner, S1
Stafstrom, CE1
Thilothammal, N2
Krishnamurthy, PV1
Kamala, KG1
Ahamed, S1
Banu, K2
Krishnamurthy, KB1
Drislane, FW1
Ratnam, RS1
Skrap, M1
Melatini, A1
Vassallo, A1
Sidoti, C1
Gokhale, R1
Huttenlocher, PR1
Brady, L1
Kirschner, BS1
Jiao, FY1
Gao, DY1
Takuma, Y1
Wu, S1
Liu, ZY1
Zhang, XK1
Lieu, NS1
Ge, ZL1
Chui, W1
Li, HR1
Cao, YM1
Bai, AN1
Liu, SB1
Rantala, H1
Tarkka, R1
Uhari, M1
Johnson, KH1
Caton, H1
Chadwick, D1
Baumann, RJ1
Khurana, DS1
Knudsen, FU3
Mellanby, J1
Milward, AJ1
Autret-Leca, E1
Ployet, JL1
Jonville-Bera, AP1
Stieg, RL1
Vestermark, S2
Fishman, MA1
Livingston, S3
Pauli, LL2
Pruce, I2
Kramer, II2
Borgheresi, S1
Luti, E1
Buti Cossi, D1
Mecherini, L1
Bardini, MR1
Burgio, E1
Ciampi, C1
Benocci, M1
Massai, S1
Lini, M1
Grifi, G1
Valenza, T1
Leiber, DU1
Lagenstein, I2
Grüttner, R1
Pascoe, JM1
Schnitzker, WF1
Carr, A1
Davis, DC1
Davidson, S1
Dale, EP1
Goldenberg, ED1
Hanson, R1
Lulejian, GA1
Nelson, MA1
Treitman, P1
Weinstein, A1
Jalling, B1
Wässer, S1
Wässer, R1
Vajnorský, J1
Gutová, M1
Ulrychová, Z1
Javitt, NB1
Thorn, I2
Ginsberg-Fellner, F1
Primack, WA1
Raispis, T1
Dworsky, ME1
Galetta, SL1
Stadtmauer, EA1
Hicks, DG1
Raps, EC1
Plock, G1
Oberholtzer, JC1
Farwell, JR1
Lee, YJ1
Sulzbacher, SI1
Ellenberg, JH1
Webb, R1
Bobele, G1
Hakeem, VF1
Herranz Fernández, JL1
Armijo Simón, JA1
Arteaga Manjón-Cabeza, R1
Brenard, R1
Geubel, AP1
Benhamou, JP1
Newton, RW1
Sehgal, VN1
Srivastava, G1
Huang, SW1
Somasundram, P1
Tan, CL1
Canagarayar, UT1
Soysa, P1
Bettis, DB1
Ater, SB1
Vining, EP1
Freeman, JM1
Rothe, B1
Gold, AP1
Arseni, C1
Marinescu, V1
Ouellette, EM1
Huott, AD1
Madison, DS1
Niedermeyer, E1
Josephson, DA1
Trubnikov, BM1
Lombroso, CT1
Faero, O2
Kastrup, KW2
Lykkegaard Nielsen, E1
Melchior, JC2
Braun, W1
Wöckel, W1
Giertler, U1
Vollmar, F1
Wilson, JT1
Wilkinson, GR1
Thorm, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464]Phase 4142 participants (Anticipated)Interventional2020-07-06Recruiting
Impact of Long Term of Benzodiazepine Use on Psychiatric Manifestation in Neuropsychiatric Disease[NCT04792658]100 participants (Anticipated)Observational2021-03-10Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

18 reviews available for phenobarbital and Recrudescence

ArticleYear
Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review.
    The Cochrane database of systematic reviews, 2018, 10-24, Volume: 10

    Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy,

2018
Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures.
    The Cochrane database of systematic reviews, 2013, Jan-31, Issue:1

    Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; I

2013
[Febrile seizures--an update].
    Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege, 2004, Volume: 23, Issue:8

    Topics: Administration, Oral; Administration, Rectal; Age Factors; Analgesics, Non-Narcotic; Anticonvulsants

2004
Benzodiazepine use, abuse, and dependence.
    The Journal of clinical psychiatry, 2005, Volume: 66 Suppl 2

    Topics: Anti-Anxiety Agents; Benzodiazepines; Delayed-Action Preparations; Humans; Long-Term Care; Phenobarb

2005
The natural history of febrile seizures.
    Annual review of medicine, 1983, Volume: 34

    Topics: Animals; Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Infant

1983
[Use of phenobarbital in febrile convulsive crisis].
    Anales espanoles de pediatria, 1983, Volume: 18, Issue:2

    Topics: Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Nervous System Diseases; Phenobarbital; Recurr

1983
Seizure disorders.
    The Veterinary clinics of North America. Small animal practice, 1980, Volume: 10, Issue:1

    Topics: Animals; Cat Diseases; Cats; Diagnosis, Differential; Diazepam; Dog Diseases; Dogs; Epilepsy; Mephob

1980
Cardioversion and defibrillation.
    American heart journal, 1980, Volume: 100, Issue:6 Pt 1

    Topics: Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Catheterization; Diazepa

1980
A meta-analytic review of the preventive treatment of recurrences of febrile seizures.
    The Journal of pediatrics, 1997, Volume: 131, Issue:6

    Topics: Anticonvulsants; Chi-Square Distribution; Child; Diazepam; Drug Administration Schedule; Fever; Huma

1997
Treatment of status epilepticus.
    Indian journal of pediatrics, 2000, Volume: 67, Issue:1 Suppl

    Topics: Anticonvulsants; Benzodiazepines; Child; Humans; Patient Compliance; Phenobarbital; Phenytoin; Pract

2000
[Febrile convulsions, Treatment and prognosis].
    Ugeskrift for laeger, 2001, Feb-19, Volume: 163, Issue:8

    Topics: Analgesics, Non-Narcotic; Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phe

2001
Febrile seizures: the treatment controversy.
    The Journal of pediatrics, 1979, Volume: 94, Issue:2

    Topics: Child; Epilepsy; Humans; Nervous System Diseases; Phenobarbital; Phenytoin; Recurrence; Seizures; Se

1979
Febrile convulsions: diagnosis, treatment, and prognosis.
    Pediatric annals, 1979, Volume: 8, Issue:3

    Topics: Child; Epilepsy; Humans; Infant; Intellectual Disability; Intelligence; Meningitis; Phenobarbital; P

1979
[Prevention of recurrences and of epilepsy in febrile convulsions. Protocol of the Pediatric Clinic of the Florence and preliminary results].
    Minerva pediatrica, 1979, Nov-30, Volume: 31, Issue:22

    Topics: Age Factors; Child; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phenobarbital; Recurrence;

1979
'Benign' familial neonatal convulsions.
    Journal of child neurology, 1990, Volume: 5, Issue:4

    Topics: Chromosome Aberrations; Chromosome Disorders; Female; Follow-Up Studies; Genes, Dominant; Humans; In

1990
Febrile seizures: emergency department diagnosis and treatment.
    The Journal of emergency medicine, 1985, Volume: 2, Issue:5

    Topics: Blood Cell Count; Blood Glucose; Child, Preschool; Counseling; Diagnosis, Differential; Diazepam; Dr

1985
The child who convulses with fever.
    Pediatric clinics of North America, 1974, Volume: 21, Issue:2

    Topics: Age Factors; Analgesics; Brain Injuries; Central Nervous System Diseases; Child; Child Behavior; Chi

1974
The treatment of status epilepticus.
    Pediatrics, 1974, Volume: 53, Issue:4

    Topics: Anti-Bacterial Agents; Anticonvulsants; Barbiturates; Brain Edema; Central Nervous System Diseases;

1974

Trials

24 trials available for phenobarbital and Recrudescence

ArticleYear
Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate.
    Brain & development, 2009, Volume: 31, Issue:6

    Topics: Anticonvulsants; Child; Child, Preschool; Dehydration; Dose-Response Relationship, Drug; Drug Admini

2009
A prospective, randomized, trial of phenobarbital versus benzodiazepines for acute alcohol withdrawal.
    The American journal of emergency medicine, 2011, Volume: 29, Issue:4

    Topics: Administration, Oral; Alcohol-Related Disorders; Chlordiazepoxide; Female; GABA Modulators; Humans;

2011
Pharmacokinetics and clinical effect of phenobarbital in children with severe falciparum malaria and convulsions.
    British journal of clinical pharmacology, 2003, Volume: 56, Issue:4

    Topics: Anticonvulsants; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Infusio

2003
Factors associated with poor control in partial complex epilepsy.
    Journal of child neurology, 2004, Volume: 19, Issue:4

    Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalograp

2004
Seizure recurrence and developmental disabilities after neonatal seizures: outcomes are unrelated to use of phenobarbital prophylaxis.
    Journal of child neurology, 2007, Volume: 22, Issue:4

    Topics: Anticonvulsants; Child; Child, Preschool; Developmental Disabilities; Epilepsy, Benign Neonatal; Fem

2007
Placebo-controlled study of phenobarbitone and phenytoin in the prophylaxis of febrile convulsions.
    Lancet (London, England), 1981, Sep-19, Volume: 2, Issue:8247

    Topics: Age Factors; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbi

1981
Phenobarbital compared with carbamazepine in prevention of recurrent febrile convulsions. A double-blind study.
    American journal of diseases of children (1960), 1983, Volume: 137, Issue:9

    Topics: Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Inf

1983
Prevention of recurrent febrile convulsions--a randomized therapeutic assay: sodium valproate, phenobarbital and placebo.
    Neuropediatrics, 1984, Volume: 15, Issue:1

    Topics: Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Electroencephalography

1984
Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions. Comparison by a double-blind trial.
    Archives of disease in childhood, 1980, Volume: 55, Issue:3

    Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Random A

1980
[Efficacy of sodium dipropylacetate compared with phenobarbital and placebo in the prevention of recurrence of febrile convulsions].
    Pediatrie, 1982, Volume: 37, Issue:6

    Topics: Child, Preschool; Clinical Trials as Topic; Female; Humans; Infant; Male; Phenobarbital; Placebos; R

1982
Long-term effect of phenobarbital on cognitive function in children with febrile convulsions.
    Pediatrics, 1981, Volume: 68, Issue:6

    Topics: Child; Child, Preschool; Cognition; Female; Humans; Male; Patient Compliance; Phenobarbital; Psychol

1981
Role of phenobarbitone in preventing recurrence of febrile convulsions.
    Indian pediatrics, 1993, Volume: 30, Issue:5

    Topics: Child; Child, Preschool; Double-Blind Method; Drug Tolerance; Epilepsies, Partial; Epilepsy, Tonic-C

1993
Comparison of phenobarbitone, phenytoin with sodium valproate: randomized, double-blind study.
    Indian pediatrics, 1996, Volume: 33, Issue:7

    Topics: Child; Child, Preschool; Epilepsy, Tonic-Clonic; Female; Humans; Phenobarbital; Phenytoin; Recurrenc

1996
Randomized, controlled trial of high-dose intravenous pyridoxine in the treatment of recurrent seizures in children.
    Pediatric neurology, 1997, Volume: 17, Issue:1

    Topics: Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combinatio

1997
Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study.
    Brain : a journal of neurology, 1999, Volume: 122 ( Pt 3)

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Combinations; Epilepsy; Female; Human

1999
Double-blind study of belladonna-ergotamine-phenobarbital for interval treatment of recurrent throbbing headache.
    Headache, 1977, Volume: 17, Issue:3

    Topics: Adult; Atropa belladonna; Clinical Trials as Topic; Drug Therapy, Combination; Ergotamine; Female; H

1977
[Prevention of febrile convulsions with diazepam or phenemal. A prospective controlled study].
    Ugeskrift for laeger, 1978, May-01, Volume: 140, Issue:18

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Humans; Infant; Phenobarbital; Prospect

1978
Prophylactic diazepam or phenobarbitone in febrile convulsions: a prospective, controlled study.
    Archives of disease in childhood, 1978, Volume: 53, Issue:8

    Topics: Child, Preschool; Clinical Trials as Topic; Diazepam; Female; Humans; Infant; Male; Phenobarbital; P

1978
The value of phenobarbital in the child who has had a single febrile seizure: a controlled prospective study.
    Pediatrics, 1977, Volume: 59, Issue:3

    Topics: Child, Preschool; Female; Humans; Infant; Male; Patient Compliance; Phenobarbital; Prospective Studi

1977
Continuous phrophylcatic anticonvulsants in selected childrens with febrile convulsions.
    Acta neurologica Scandinavica. Supplementum, 1975, Volume: 60

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Female; Fever; Follow-Up Studies; Humans; Infant;

1975
A controlled study of profylactic long-term treatment of febrile convulsions with phenobarbital.
    Acta neurologica Scandinavica. Supplementum, 1975, Volume: 60

    Topics: Child, Preschool; Clinical Trials as Topic; Fever; Follow-Up Studies; Humans; Infant; Phenobarbital;

1975
Phenobarbital for febrile seizures--effects on intelligence and on seizure recurrence.
    The New England journal of medicine, 1990, Feb-08, Volume: 322, Issue:6

    Topics: Child, Preschool; Cognition; Female; Humans; Infant; Intelligence; Male; Phenobarbital; Randomized C

1990
Randomised controlled trials of phenobarbitone and valproate in febrile convulsions.
    Archives of disease in childhood, 1988, Volume: 63, Issue:10

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Phenobarbital; Random Allocation;

1988
Successful prophylaxis of febrile convulsions with phenobarbital.
    Epilepsia, 1972, Volume: 13, Issue:2

    Topics: Age Factors; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Female; Fever; Follow-Up S

1972

Other Studies

79 other studies available for phenobarbital and Recrudescence

ArticleYear
Late Recurrences After Estrogen Receptor-Positive Breast Cancer.
    JAMA oncology, 2020, 02-01, Volume: 6, Issue:2

    Topics: Breast Neoplasms; Humans; Phenobarbital; Postmenopause; Receptors, Estrogen; Recurrence; Tamoxifen

2020
50 Years Ago in TheJournalofPediatrics: Intermittent Phenobarbital Treatment to Prevent Recurrent Febrile Seizures.
    The Journal of pediatrics, 2021, Volume: 233

    Topics: Anticonvulsants; History, 20th Century; Humans; Pediatrics; Periodicals as Topic; Phenobarbital; Rec

2021
Evaluation of Patients With Febrile Seizure: Risk Factors, Reccurence, Treatment and Prognosis.
    Pediatric emergency care, 2020, Volume: 36, Issue:4

    Topics: Anticonvulsants; Child, Preschool; Electroencephalography; Epilepsy; Female; Fever; Humans; Infant;

2020
[11C]quinidine and [11C]laniquidar PET imaging in a chronic rodent epilepsy model: impact of epilepsy and drug-responsiveness.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:6

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzazepines; Carbon Radioisotopes

2013
Index of suspicion.
    Pediatrics in review, 2014, Volume: 35, Issue:5

    Topics: Adolescent; Consciousness Disorders; Coronary Vessel Anomalies; Cough; Diagnosis, Differential; Drug

2014
High seizure frequency prior to antiepileptic treatment is a predictor of pharmacoresistant epilepsy in a rat model of temporal lobe epilepsy.
    Epilepsia, 2010, Volume: 51, Issue:1

    Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Diazepam; Disease Models, Animal; Dose-Respons

2010
Chitosan may decrease serum valproate and increase the risk of seizure reappearance.
    BMJ (Clinical research ed.), 2009, Sep-24, Volume: 339

    Topics: Adult; Anti-Obesity Agents; Anticonvulsants; Chitosan; Dietary Supplements; Drug Interactions; Epile

2009
Congenital hypoplasia of the Internal Carotid Artery.
    Indian journal of pediatrics, 2009, Volume: 76, Issue:10

    Topics: Apgar Score; Carotid Artery, Internal; Cerebral Angiography; Follow-Up Studies; Humans; Imaging, Thr

2009
[Prophylactic efficacy of levetiracetam, valproate or phenobarbital on febrile convulsions in rats].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2010, Volume: 12, Issue:7

    Topics: Animals; Anticonvulsants; Levetiracetam; Male; Phenobarbital; Piracetam; Rats; Recurrence; Seizures,

2010
Add-on treatment with verapamil in pharmacoresistant canine epilepsy.
    Epilepsia, 2011, Volume: 52, Issue:2

    Topics: Age of Onset; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blo

2011
Recooling for rebound seizures after rewarming in neonatal encephalopathy.
    Pediatrics, 2012, Volume: 130, Issue:2

    Topics: Anticonvulsants; Combined Modality Therapy; Electroencephalography; Humans; Hypothermia, Induced; Hy

2012
MEGALOBLASTIC ANAEMIA ASSOCIATED WITH ANTICONVULSANT DRUGS: STUDIES ON A CASE WITH FOUR RELAPSES.
    Acta medica Scandinavica, 1965, Volume: 177

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Drug Therapy; Electrophoresis; Epilepsy;

1965
Effects of creatine and cyclocreatine supplementation on kainate induced injury in pre-pubescent rats.
    Brain injury, 2004, Volume: 18, Issue:12

    Topics: Acute Disease; Aggression; Animals; Anticonvulsants; Creatine; Creatinine; Dietary Supplements; Emot

2004
[Recurrent bilateral shoulder hand syndrome induced by phenobarbital].
    La Tunisie medicale, 2003, Volume: 81, Issue:9

    Topics: Aged; Anticonvulsants; Female; Humans; Phenobarbital; Recurrence; Reflex Sympathetic Dystrophy

2003
Toxoplasma gondii brain granuloma in a cat: diagnosis using cytology from an intraoperative sample and sequential magnetic resonance imaging.
    The Journal of small animal practice, 2008, Volume: 49, Issue:2

    Topics: Animals; Cat Diseases; Cats; Clindamycin; Fatal Outcome; Granuloma; Magnetic Resonance Imaging; Male

2008
A case of repeated coma in an 8-year-old boy.
    Tropical doctor, 2007, Volume: 37, Issue:4

    Topics: Anticonvulsants; Child; Coma; Humans; Male; Phenobarbital; Porphyria, Acute Intermittent; Recurrence

2007
Very high dose phenobarbital for refractory status epilepticus.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2007, Volume: 90, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Female; Humans; Male; Middle Aged; Phen

2007
Phenobarbitone in the prophylaxis of febrile convulsions.
    Lancet (London, England), 1981, Nov-07, Volume: 2, Issue:8254

    Topics: Humans; Phenobarbital; Recurrence; Seizures, Febrile

1981
Febrile convulsions.
    Australian family physician, 1983, Volume: 12, Issue:9

    Topics: Anticonvulsants; Child, Preschool; Diazepam; Female; Fever; Humans; Infant; Male; Phenobarbital; Rec

1983
[Continuous oral phenobarbital or intermittent rectal diazepam for the prevention of febrile convulsions].
    Anales espanoles de pediatria, 1984, Volume: 20, Issue:8

    Topics: Administration, Oral; Child, Preschool; Diazepam; Female; Humans; Infant; Longitudinal Studies; Male

1984
[Efficacy and failure of phenobarbital in the prevention of febrile convulsions. Importance of familial antecedents].
    Anales espanoles de pediatria, 1983, Volume: 18, Issue:2

    Topics: Age Factors; Epilepsy; Female; Fetal Hypoxia; Humans; Male; Phenobarbital; Pregnancy; Recurrence; Se

1983
Febrile convulsions: their significance for later intellectual development and behaviour.
    Journal of child psychology and psychiatry, and allied disciplines, 1984, Volume: 25, Issue:1

    Topics: Child; Child Behavior Disorders; Child Development; Child, Preschool; Female; Follow-Up Studies; Hum

1984
Drug treatment of recurrent febrile seizures.
    American journal of diseases of children (1960), 1984, Volume: 138, Issue:5

    Topics: Antacids; Child; Humans; Phenobarbital; Recurrence; Seizures, Febrile

1984
Successful prophylaxis against febrile convulsions with valproic acid or phenobarbitone.
    British medical journal, 1980, Feb-09, Volume: 280, Issue:6211

    Topics: Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Recurrence; Seizures; Seizures, Febri

1980
Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions.
    Archives of disease in childhood, 1980, Volume: 55, Issue:8

    Topics: Humans; Infant; Infant, Newborn; Phenobarbital; Recurrence; Seizures; Seizures, Febrile; Valproic Ac

1980
Consensus statement. Febrile seizures: long-term management of children with fever-associated seizures.
    Pediatrics, 1980, Volume: 66, Issue:6

    Topics: Anticonvulsants; Child, Preschool; Epilepsy; Fever; Humans; Infant; Long-Term Care; National Institu

1980
Prophylaxis and febrile convulsions.
    Archives of disease in childhood, 1981, Volume: 56, Issue:2

    Topics: Child; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phenobarbital; Recurrence; Seizures; Se

1981
Febrile convulsions: long-term treatment.
    British medical journal (Clinical research ed.), 1981, Feb-28, Volume: 282, Issue:6265

    Topics: Anticonvulsants; Child; Child, Preschool; Humans; Infant; Phenobarbital; Prognosis; Recurrence; Seiz

1981
Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions.
    Brain & development, 1981, Volume: 3, Issue:4

    Topics: Child, Preschool; Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Primidone; Recurr

1981
Febrile convulsions: intellectual progress in relation to anticonvulsant therapy and to recurrence of fits.
    Archives of disease in childhood, 1982, Volume: 57, Issue:2

    Topics: Child Development; Child, Preschool; Humans; Infant; Intelligence; Intelligence Tests; Phenobarbital

1982
Neurologic aspects and treatment of La Crosse encephalitis.
    Progress in clinical and biological research, 1983, Volume: 123

    Topics: Brain Edema; Child; Encephalitis, Arbovirus; Encephalitis, California; Humans; Phenobarbital; Phenyt

1983
Recurrent spontaneous myoclonus in alcohol withdrawal.
    Southern medical journal, 1983, Volume: 76, Issue:8

    Topics: Adult; Aged; Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Ethanol; Femal

1983
Duration of treatment for childhood epilepsy.
    Developmental medicine and child neurology, 1982, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Follow-Up Studies; Humans; Infant; Phenobarbit

1982
Carbamazepine does not prevent febrile seizures in phenobarbital failures.
    Neurology, 1982, Volume: 32, Issue:3

    Topics: Carbamazepine; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Recurrence; Seizures,

1982
Prophylaxis against febrile convulsions with phenobarbital. A 3-year prospective investigation.
    Acta paediatrica Scandinavica, 1981, Volume: 70, Issue:1

    Topics: Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Male; Phenobarbital; Prospective

1981
[Familial recurring intrahepatic cholestasis of the Tygstrup-Summerskill-Walshe type].
    Monatsschrift fur Kinderheilkunde, 1980, Volume: 128, Issue:5

    Topics: Adult; Child, Preschool; Cholestasis; Cholestyramine Resin; Female; Humans; Liver; Male; Phenobarbit

1980
Low risk of seizure recurrence after early withdrawal of antiepileptic treatment in the neonatal period.
    Archives of disease in childhood. Fetal and neonatal edition, 1995, Volume: 72, Issue:2

    Topics: Anticonvulsants; Diazepam; Drug Administration Schedule; Electroencephalography; Humans; Infant, Low

1995
Mexiletine overdose producing status epilepticus without cardiovascular abnormalities.
    Journal of toxicology. Clinical toxicology, 1994, Volume: 32, Issue:6

    Topics: Adult; Blood Pressure; Cardiovascular System; Diazepam; Drug Overdose; Drug Therapy, Combination; El

1994
Phenobarbital modifies seizure-related brain injury in the developing brain.
    Annals of neurology, 1994, Volume: 36, Issue:3

    Topics: Aging; Analysis of Variance; Animals; Brain Diseases; Kainic Acid; Male; Phenobarbital; Rats; Rats,

1994
Relapse and survival after barbiturate anesthetic treatment of refractory status epilepticus.
    Epilepsia, 1996, Volume: 37, Issue:9

    Topics: Adult; Anesthetics, Intravenous; Electroencephalography; Humans; Hypotension; Infusions, Intravenous

1996
Stereotactic aspiration and drainage of brain abscesses. Experience with 9 cases.
    Minimally invasive neurosurgery : MIN, 1996, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Aged; Brain Abscess; Catheterization, Peripheral; Ceftriaxone; Cephalosporins; Dr

1996
Use of barbiturates in the treatment of cyclic vomiting during childhood.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 25, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Mal

1997
Initial treatment of generalized convulsive status epilepticus.
    The Journal of family practice, 1999, Volume: 48, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Diazepam; Double-Blind Method; Electroencephalography; Emergenci

1999
Technical report: treatment of the child with simple febrile seizures.
    Pediatrics, 1999, Volume: 103, Issue:6

    Topics: Analgesics, Non-Narcotic; Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phe

1999
Do fits really beget fits? The effect of previous epileptic activity on the subsequent induction of the tetanus toxin model of limbic epilepsy in the rat.
    Neurobiology of disease, 2001, Volume: 8, Issue:4

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists

2001
[Treatment of febrile convulsions].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2002, Volume: 9, Issue:1

    Topics: Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child, Preschool; Diazepam; D

2002
Medical treatment of epilepsy: part I.
    Southern medical journal, 1978, Volume: 71, Issue:3

    Topics: Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combina

1978
Continuous phenobarbital treatment after a 'simple febrile convulsion'.
    American journal of diseases of children (1960), 1979, Volume: 133, Issue:2

    Topics: Animals; Child; Epilepsy; Humans; Phenobarbital; Recurrence; Seizures; Seizures, Febrile

1979
[Benign recurrent cholestasis in monozygotic twin girls (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1979, Volume: 127, Issue:1

    Topics: Child; Child, Preschool; Cholestasis; Cholestyramine Resin; Diseases in Twins; Female; Humans; Pheno

1979
Behavior disturbance, phenobarbital, and febrile seizures.
    Pediatrics, 1978, Volume: 61, Issue:5

    Topics: Barbiturates; Child Behavior Disorders; Humans; Hyperkinesis; Mephobarbital; Phenobarbital; Recurren

1978
Simple febrile seizures.
    American journal of diseases of children (1960), 1978, Volume: 132, Issue:7

    Topics: Child; Community Participation; Decision Making; Humans; Parents; Phenobarbital; Recurrence; Seizure

1978
'Simple febrile convulsion'.
    American journal of diseases of children (1960), 1978, Volume: 132, Issue:7

    Topics: Humans; Phenobarbital; Recurrence; Seizures; Seizures, Febrile

1978
Phenobarbital and febrile seizures.
    Pediatrics, 1978, Volume: 61, Issue:6

    Topics: Drug Administration Schedule; Humans; Phenobarbital; Recurrence; Seizures; Seizures, Febrile

1978
Problems of childhood. Febrile fits.
    British medical journal, 1976, Feb-07, Volume: 1, Issue:6005

    Topics: Age Factors; Child, Preschool; Diazepam; Epilepsy, Tonic-Clonic; Female; Fever; Humans; Infant; Male

1976
[Phenemal prophylaxis and prognosis].
    Lakartidningen, 1977, Mar-16, Volume: 74, Issue:11

    Topics: Child; Child, Preschool; Epilepsy; Humans; Infant; Phenobarbital; Prognosis; Recurrence; Seizures; S

1977
The effectiveness of phenobarbital in the prevention of recurrent febrile convulsions in children with and without a history of pre-, peri- and postnatal abnormalities.
    Acta paediatrica Scandinavica, 1977, Volume: 66, Issue:5

    Topics: Child; Child, Preschool; Female; Follow-Up Studies; Humans; Obstetric Labor Complications; Phenobarb

1977
[Interval therapy of febrile convulsions for the management of their prognosis. I. Methods and therapeutic advice for interval therapy of febrile convulsions].
    Kinderarztliche Praxis, 1976, Volume: 44, Issue:11

    Topics: Child, Preschool; Epilepsy; Humans; Infant; Periodicity; Phenobarbital; Phenytoin; Recurrence; Seizu

1976
[Problems in the preventive treatment of repeated febrile convulsions].
    Ceskoslovenska pediatrie, 1976, Volume: 31, Issue:11

    Topics: Child; Child, Preschool; Chronic Disease; Female; Humans; Infant; Male; Phenobarbital; Prognosis; Re

1976
Cholestasis in infancy. Status report and conceptual approach.
    Gastroenterology, 1976, Volume: 70, Issue:6

    Topics: alpha 1-Antitrypsin Deficiency; Anion Exchange Resins; Bacterial Infections; Bile; Bile Ducts; Bile

1976
Recurrent hyperosmolar nonketotic episodes in a young diabetic.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:2

    Topics: Blood Glucose; Chlorides; Dehydration; Diabetes Mellitus, Type 1; Diabetic Coma; Female; Glucose; Hu

1975
Benign Familial Neonatal Seizures.
    Alabama medicine : journal of the Medical Association of the State of Alabama, 1992, Volume: 62, Issue:5

    Topics: Adult; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 20; Diagnosis, Differe

1992
Reactive lymphohistiocytosis with recurrence in the optic chiasm.
    Journal of clinical neuro-ophthalmology, 1991, Volume: 11, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Cranial Nerve Diseases; Histiocytosis, Non-Langerhans-Cell; Humans;

1991
EEG monitoring of therapy for neonatal seizures.
    Developmental medicine and child neurology, 1990, Volume: 32, Issue:10

    Topics: Anticonvulsants; Chloral Hydrate; Clonazepam; Diazepam; Drug Therapy, Combination; Electroencephalog

1990
[Factors influencing the effectiveness of preventive treatment of febrile convulsions].
    Anales espanoles de pediatria, 1989, Volume: 31, Issue:2

    Topics: Anticonvulsants; Child; Drug Evaluation; Epilepsy; Female; Fever; Humans; Male; Phenobarbital; Primi

1989
Benign recurrent intrahepatic cholestasis. A report of 26 cases.
    Journal of clinical gastroenterology, 1989, Volume: 11, Issue:5

    Topics: Adult; Cholestasis, Intrahepatic; Cholestyramine Resin; Female; Humans; Male; Phenobarbital; Plasmap

1989
Epilepsy and mental retardation following febrile seizures in childhood.
    Acta paediatrica Scandinavica, 1989, Volume: 78, Issue:2

    Topics: Child; Child, Preschool; Epilepsy; Humans; Infant; Intellectual Disability; Phenobarbital; Recurrenc

1989
Corticosteroid-unresponsive pemphigus vulgaris following antiepileptic therapy.
    International journal of dermatology, 1988, Volume: 27, Issue:4

    Topics: Adult; Drug Interactions; Epilepsy; Humans; Male; Pemphigus; Phenobarbital; Phenytoin; Prednisolone;

1988
The value of investigations, the significance of perinatal and family histories and the prevalence of side effects to phenobarbitone in children with recurrent seizures.
    Singapore medical journal, 1986, Volume: 27, Issue:6

    Topics: Child Behavior; Epilepsy; Female; Humans; Infant, Newborn; Male; Phenobarbital; Pregnancy; Recurrenc

1986
Management of febrile seizures in a developing country.
    The Journal of tropical medicine and hygiene, 1987, Volume: 90, Issue:4

    Topics: Child; Child, Preschool; Developing Countries; Humans; Infant; Medicine, Ayurvedic; Medicine, Tradit

1987
Where, why, and what type of therapy.
    Pediatric annals, 1985, Volume: 14, Issue:11

    Topics: Carbamazepine; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Hum

1985
Recurrence of febrile convulsions and phenobarbital treatment.
    Acta paediatrica Scandinavica, 1985, Volume: 74, Issue:2

    Topics: Child; Humans; Phenobarbital; Recurrence; Risk; Seizures, Febrile

1985
Psychomotor epilepsy in childhood.
    Pediatrics, 1974, Volume: 53, Issue:4

    Topics: Bromides; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; E

1974
Epilepsy in cerebral hydatidosis.
    Epilepsia, 1974, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Brain Diseases; Child; Child, Preschool; Dominance, Cerebral; Echinococcosis; Ele

1974
Occipital lobe epilepsy. A clinical and electroencephalographic study.
    European neurology, 1974, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Blindness; Child; Diagnosis, Differential; Electroencephalography; Epilepsy; Epil

1974
Status epilepticus.
    American family physician, 1974, Volume: 10, Issue:4

    Topics: Diazepam; Epilepsy; Humans; Hypocalcemia; Hypoglycemia; Magnesium Deficiency; Paraldehyde; Phenobarb

1974
[Disability and rehabilitation expertise regarding patients with diencephalic autonomic-vascular paroxysms].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1974, Volume: 74, Issue:9

    Topics: Adolescent; Adult; Ambulatory Care; Angina Pectoris; Anti-Bacterial Agents; Atropa belladonna; Blood

1974
[Phenobarbital treatment of benign recurrent intrahepatic cholestasis].
    Schweizerische medizinische Wochenschrift, 1972, Dec-02, Volume: 102, Issue:48

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Biopsy; Cholestasis; Female; Humans; I

1972
Delivery of anticonvulsant drug therapy in epileptic patients assessed by plasma level analyses.
    Neurology, 1974, Volume: 24, Issue:7

    Topics: Adolescent; Adult; Child; Chromatography, Gas; Drug Therapy; Electroencephalography; Epilepsy; Human

1974
Phenobarbital as prophylaxis for febrile convulsions. A preliminary report.
    Epilepsia, 1971, Volume: 12, Issue:1

    Topics: Age Factors; Ataxia; Child, Preschool; Dermatitis, Contact; Female; Fever; Humans; Infant; Male; Phe

1971